Click here to switch to the map view.

The map label for this gene is yhcA [H]

Identifier: 148652912

GI number: 148652912

Start: 1355315

End: 1356799

Strand: Direct

Name: yhcA [H]

Synonym: PsycPRwf_1105

Alternate gene names: 148652912

Gene position: 1355315-1356799 (Clockwise)

Preceding gene: 148652911

Following gene: 148652913

Centisome position: 45.5

GC content: 47.88

Gene sequence:

>1485_bases
ATGACACACTTATCACCGCCGCCTGGCTCGTTATCACAACAAGCCTACCGTGAGGATCCAGATAGCCGCCAAGTACGCCG
AGTGCTGTGGACCTTGCTATTGGGCGGCACAGTGGTCAGCTTTAGCAACAGTGCGTTAAACCCGGCCATCCCTGTTTTTA
TGTCCATATTTTCAGTAGATATTGTGACAGGAAGCTGGCTGTTAAATGGCTATGTACTGGCAATGAGTGTGGGTCTGATG
CTCAGTGGCTATTTGAGCAAGGCCTTTTATTTTAAGCAGGTATATATCTGCGCCATTACTGGATTTATGATGGGCTCAGT
GCTGGGTATGTCAGCTACCAGCTTGTCATTGATTATTATAGCAAGAGTCATTCAAGGACTGGCAGGCGGCTTAATTATCC
CCTTATCCATCGGCCTGTTATATCAGGTGTATCCCAGCGCTCAGCAAGGCCGAGCTATGGCGTTGTGGGGGATAGTCATT
ATGATGTCTTTGGCTTTTGGCCCCTTAGTTGGGGCTTTTTTAGTGGCACATTTTGCATGGTGGACTTTATTTGCCATAAC
CTTACCGCTTAGCGCCTTGGTGGTGGCCATGGCAATGAAGTGGCTGCCCTGGCTACCTGAGCACCAAGCACCAAAAACCC
GCCACAAGCCGTTTGATAAAAAGGGCTTTATGGGATTGCTGCTTTGGCTACTGGCACTAAGCTTATGGCTCAATACCTTA
AAGTCAGATTCTGCGATGCAAAGCAATGGCTTGATTCAATTGGTGCTGCTGGCCGGCTTTGTGATCACGGCTATCATCTG
GTGGCGCTATGAGCAACGACAGTCAAACCCGCTACTCAATGTCAATTTGTTTGCCAATAAAACTTACTTGCACAGCACAA
TATTAAGTATCACCCAGACAATTGGTCTAATGATGGGCCTGCTATTTTTGCCTATTATCATTCAGCAAATAATGCACAAA
AGCGCGATGTGGACAGGCTTGGTGTTAATGTTTGCCACCTTGATTGCCAGTGTGACCACTCATATTGCTGGCGGTATTGT
TGATAAATATGGCGCTAGGGATATTGGCAGTGCAGGGGTGGTTATCAGTGCGGCCTCTATGCTGATGCTAGCTTGGGGCT
TAGCGACGCCTAATATCTGGCTAATGATGCTGGTCATGGGCGTCCAGGGAGTGGGAACAGGATTGGCCTATTTACCCACC
ACAACTGTTGGGTTGAGTAGTCTGGATAAGCCTATGGTGACCGAGGGCGCCGCCTTAAATAATATCAGTCGCCGTATTGT
CTCTACCCTGTTTATTGCGCTCGCAACCTTATATATCAATGGTGAAGGACTGGGGATATTGATAAAGCTCATGCCAAGCT
TATCAGAAGCTCACGCGCTAGTAGCACCGATGCAAGAGGTGTTTGTGGGACTGGCGATGCTATTGTTGATGACGCTTATT
TCTGCCAGACAGCTGCCATCTGGGTTATCAGATAATTCAGAGTAG

Upstream 100 bases:

>100_bases
TGCCGGCAGGCACCATAGCCGCTATCATTGGGGGACTGTACTTTATATGGCTCATTCGGCGCAGTTCGGTTCATCAGTAA
GCTAAGATTAGCATTATCTG

Downstream 100 bases:

>100_bases
ATAGAGATAGATAAGCATGAGTGATAAAAATAATAAGCTAAGACAGCGGCCTAAAATAGCAATTAATGATTGAAATAATT
ATGTTTATTTAACTTTTGGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MTHLSPPPGSLSQQAYREDPDSRQVRRVLWTLLLGGTVVSFSNSALNPAIPVFMSIFSVDIVTGSWLLNGYVLAMSVGLM
LSGYLSKAFYFKQVYICAITGFMMGSVLGMSATSLSLIIIARVIQGLAGGLIIPLSIGLLYQVYPSAQQGRAMALWGIVI
MMSLAFGPLVGAFLVAHFAWWTLFAITLPLSALVVAMAMKWLPWLPEHQAPKTRHKPFDKKGFMGLLLWLLALSLWLNTL
KSDSAMQSNGLIQLVLLAGFVITAIIWWRYEQRQSNPLLNVNLFANKTYLHSTILSITQTIGLMMGLLFLPIIIQQIMHK
SAMWTGLVLMFATLIASVTTHIAGGIVDKYGARDIGSAGVVISAASMLMLAWGLATPNIWLMMLVMGVQGVGTGLAYLPT
TTVGLSSLDKPMVTEGAALNNISRRIVSTLFIALATLYINGEGLGILIKLMPSLSEAHALVAPMQEVFVGLAMLLLMTLI
SARQLPSGLSDNSE

Sequences:

>Translated_494_residues
MTHLSPPPGSLSQQAYREDPDSRQVRRVLWTLLLGGTVVSFSNSALNPAIPVFMSIFSVDIVTGSWLLNGYVLAMSVGLM
LSGYLSKAFYFKQVYICAITGFMMGSVLGMSATSLSLIIIARVIQGLAGGLIIPLSIGLLYQVYPSAQQGRAMALWGIVI
MMSLAFGPLVGAFLVAHFAWWTLFAITLPLSALVVAMAMKWLPWLPEHQAPKTRHKPFDKKGFMGLLLWLLALSLWLNTL
KSDSAMQSNGLIQLVLLAGFVITAIIWWRYEQRQSNPLLNVNLFANKTYLHSTILSITQTIGLMMGLLFLPIIIQQIMHK
SAMWTGLVLMFATLIASVTTHIAGGIVDKYGARDIGSAGVVISAASMLMLAWGLATPNIWLMMLVMGVQGVGTGLAYLPT
TTVGLSSLDKPMVTEGAALNNISRRIVSTLFIALATLYINGEGLGILIKLMPSLSEAHALVAPMQEVFVGLAMLLLMTLI
SARQLPSGLSDNSE
>Mature_493_residues
THLSPPPGSLSQQAYREDPDSRQVRRVLWTLLLGGTVVSFSNSALNPAIPVFMSIFSVDIVTGSWLLNGYVLAMSVGLML
SGYLSKAFYFKQVYICAITGFMMGSVLGMSATSLSLIIIARVIQGLAGGLIIPLSIGLLYQVYPSAQQGRAMALWGIVIM
MSLAFGPLVGAFLVAHFAWWTLFAITLPLSALVVAMAMKWLPWLPEHQAPKTRHKPFDKKGFMGLLLWLLALSLWLNTLK
SDSAMQSNGLIQLVLLAGFVITAIIWWRYEQRQSNPLLNVNLFANKTYLHSTILSITQTIGLMMGLLFLPIIIQQIMHKS
AMWTGLVLMFATLIASVTTHIAGGIVDKYGARDIGSAGVVISAASMLMLAWGLATPNIWLMMLVMGVQGVGTGLAYLPTT
TVGLSSLDKPMVTEGAALNNISRRIVSTLFIALATLYINGEGLGILIKLMPSLSEAHALVAPMQEVFVGLAMLLLMTLIS
ARQLPSGLSDNSE

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=418, Percent_Identity=25.8373205741627, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789042, Length=407, Percent_Identity=23.8329238329238, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788710, Length=411, Percent_Identity=23.6009732360097, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1790195, Length=420, Percent_Identity=19.7619047619048, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788392, Length=409, Percent_Identity=23.2273838630807, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53462; Mature: 53331

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCCC
>Mature Secondary Structure 
THLSPPPGSLSQQAYREDPDSRQVRRVLWTLLLGGTVVSFSNSALNPAIPVFMSIFSVD
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHHH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HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8969498 [H]