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The map label for this gene is trpF [H]

Identifier: 148652563

GI number: 148652563

Start: 899339

End: 899998

Strand: Direct

Name: trpF [H]

Synonym: PsycPRwf_0754

Alternate gene names: 148652563

Gene position: 899339-899998 (Clockwise)

Preceding gene: 148652561

Following gene: 148652564

Centisome position: 30.19

GC content: 48.48

Gene sequence:

>660_bases
ATGCAGATAAAGTTTTGCGGATTTACCCAAATACAAGATGTTAAGCAAGCAGTGGCAGTTGGCGCTGATGCTTTGGGTTT
TGTGTTTTATCCGCCAAGCCCTCGAGCAGTGACCGCCATGCAGGCACGTGAGCTGATGCAGCATATCCCTGCTTTTGTTA
GTGTGGTGGCATTGGTGGTCAATATGAATAAAGACGCGCTGATTGAGCTTGCTAATACTGCTACTTTTGATGTGATTCAG
TTTCATGGTGATGAGACGCCAGAGCAGTGTCAGTCACTAGCCCAAGCCGTGAACAAACGCTGGATTAAAGCACTTCGTAT
TAATAAAGAGCAAGATACGCCTGACTCGATTCGAGCCCAGATTGACGCCTTTGCACAAGCCGGTGCCAGCAGTATCTTAC
TTGATGCCTATCATAAACAGGCGTATGGCGGTACAGGGGAGCGCTTTGATTGGTCGCTCATTCCAAAAGATGCCAGCCTG
CCTATCATTTTGGCAGGCGGGCTAACCCCTGAAAATGTGAGTGAGGTTATTAATCAGAGTTTACCGATACAGGCTGTGGA
TGTAAGCGGTGGCATTGAGTCGGCAAAGGGTATCAAAGATGCGGGCAAGATGGCGGCCTTTGTTCGCGCCGTTAAAAGTA
ATCGATGGCAACACGGTTAG

Upstream 100 bases:

>100_bases
AACAAGTATATTAAGTCAATTAAGTCTGTTAAATCAATTCAACCTACTAATGAATAAAAGAACATCAATTGACTAAAGCA
GATAAATCAATGAGGGCACG

Downstream 100 bases:

>100_bases
TACGATTTGCAGTCGCAGTCATCACCAATATACGCTGCCCATACCCAATAAATAAACACAGTAAGATACAATCATACGGC
GCACAGCGTCAGCCAGCTTA

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MQIKFCGFTQIQDVKQAVAVGADALGFVFYPPSPRAVTAMQARELMQHIPAFVSVVALVVNMNKDALIELANTATFDVIQ
FHGDETPEQCQSLAQAVNKRWIKALRINKEQDTPDSIRAQIDAFAQAGASSILLDAYHKQAYGGTGERFDWSLIPKDASL
PIILAGGLTPENVSEVINQSLPIQAVDVSGGIESAKGIKDAGKMAAFVRAVKSNRWQHG

Sequences:

>Translated_219_residues
MQIKFCGFTQIQDVKQAVAVGADALGFVFYPPSPRAVTAMQARELMQHIPAFVSVVALVVNMNKDALIELANTATFDVIQ
FHGDETPEQCQSLAQAVNKRWIKALRINKEQDTPDSIRAQIDAFAQAGASSILLDAYHKQAYGGTGERFDWSLIPKDASL
PIILAGGLTPENVSEVINQSLPIQAVDVSGGIESAKGIKDAGKMAAFVRAVKSNRWQHG
>Mature_219_residues
MQIKFCGFTQIQDVKQAVAVGADALGFVFYPPSPRAVTAMQARELMQHIPAFVSVVALVVNMNKDALIELANTATFDVIQ
FHGDETPEQCQSLAQAVNKRWIKALRINKEQDTPDSIRAQIDAFAQAGASSILLDAYHKQAYGGTGERFDWSLIPKDASL
PIILAGGLTPENVSEVINQSLPIQAVDVSGGIESAKGIKDAGKMAAFVRAVKSNRWQHG

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=213, Percent_Identity=29.5774647887324, Blast_Score=83, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320210, Length=225, Percent_Identity=32, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 23678; Mature: 23678

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKFCGFTQIQDVKQAVAVGADALGFVFYPPSPRAVTAMQARELMQHIPAFVSVVALVV
CEEEECCCHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NMNKDALIELANTATFDVIQFHGDETPEQCQSLAQAVNKRWIKALRINKEQDTPDSIRAQ
CCCHHHHEEHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
IDAFAQAGASSILLDAYHKQAYGGTGERFDWSLIPKDASLPIILAGGLTPENVSEVINQS
HHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCHHHHHHHHCCC
LPIQAVDVSGGIESAKGIKDAGKMAAFVRAVKSNRWQHG
CCEEEEECCCCCCHHHCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQIKFCGFTQIQDVKQAVAVGADALGFVFYPPSPRAVTAMQARELMQHIPAFVSVVALVV
CEEEECCCHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NMNKDALIELANTATFDVIQFHGDETPEQCQSLAQAVNKRWIKALRINKEQDTPDSIRAQ
CCCHHHHEEHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
IDAFAQAGASSILLDAYHKQAYGGTGERFDWSLIPKDASLPIILAGGLTPENVSEVINQS
HHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCHHHHHHHHCCC
LPIQAVDVSGGIESAKGIKDAGKMAAFVRAVKSNRWQHG
CCEEEEECCCCCCHHHCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2299982; 2211532 [H]