Click here to switch to the map view.

The map label for this gene is trpB [H]

Identifier: 148652564

GI number: 148652564

Start: 900126

End: 901373

Strand: Direct

Name: trpB [H]

Synonym: PsycPRwf_0755

Alternate gene names: 148652564

Gene position: 900126-901373 (Clockwise)

Preceding gene: 148652563

Following gene: 148652565

Centisome position: 30.22

GC content: 49.36

Gene sequence:

>1248_bases
ATGACAACATTTGATAATATTCCGCACAATGATGAGATTGACGATATCCAAGATTTTAATCAGTATCCAGATGCCAGTGG
TCACTTTGGTATCCATGGCGGCCGCTTCGTATCAGAGACTCTAATGGCGGCATTAGAGGAGCTTGAGACCTTATATTATC
AAGTCAAACAAGACCCTGCATTTTGGCAGGAGTACCACAATGACTTAGTCAATTATGTGGGTCGTCCAACGCCGCTTTAT
CATGCCAAGCGTTTGAGTGATGAGATTGGCGGCGCGCAGATTTATTTTAAGCGTGAAGATTTAAACCACACCGGCGCGCA
CAAAGTAAACAACACCATCGGTCAGGCGCTACTGGCTAAGATGAGCGGCAAAAAACGTATTATTGCCGAGACCGGTGCGG
GTCAACATGGCGTGGCAACAGCGACGATTGCAGCACGGCTAGGACTTGAGTGTATTATTTATATGGGCGCAGATGACGTC
GAGCGTCAAAAAATGAACGTGTATCGTATGCGTCTGCTTGGGGCTAAAGTGGTGGCGGTTGAGTCTGGTTCACGGACGCT
AAAAGATGCGATGAACGAGGCGATGCGTGATTGGGTGACCAATGTTGATACCACCTATTATATTATTGGTACGGTCGCAG
GGCCGCACCCTTATCCGTTATTGGTGCGTGATTTTCAGGCCATTATTGGTAAAGAGGCGCGTCTGCAGCATCTAGAGAAA
ACCGGCAAACTGCCTGATGCACTTGTCGCCTGTGTGGGCGGCGGATCCAATGCCATTGGTCTGTTCTATGAGTTCTTAAA
TGATACCGATGTCAAAATGTATGGCGTAGAGGCGACAGGTGATGGTATCGAAACCGGCCGTCACTCAGCGCCGCTAGCGG
CAGGCCGCGTCGGGGTGTTGCATGGCAATCGCACTTATCTGATGGCCGATGATGATGGTCAGATCCTAGAGACGCATTCA
ATCTCAGCAGGTCTTGATTATCCGGGCGTGGGCCCTGAGCACAGCTTCTTAAAAGATGTGAAGCGGGTAGAGTATGTGGG
CTGTACTGATAAAGAGGCGCTACATGGTTTTCATGAAGTGACCCGAAAAGAAGGTATTATTCCGGCGCTTGAGTCCTCGC
ACGCGGTCGCTTATGCCTTACAGCTTGCCAAAACCATGAGTCCTGAGCAGAGCATCATCGTCAATATGTCAGGCCGTGGT
GATAAGGATTTGCACTCGGTAATGAAGGCTGAAGGCATTGAGCTTTAA

Upstream 100 bases:

>100_bases
ATATACGCTGCCCATACCCAATAAATAAACACAGTAAGATACAATCATACGGCGCACAGCGTCAGCCAGCTTAATTAAAA
AAAACAGGGTGAAAAAAATT

Downstream 100 bases:

>100_bases
GCCAATTATTTAATACAGCGGGCGTGTTATAGGCCCGCAGCAGTTATCACCTTATATGTTAAGAGACCATCATGACTCGA
ATTGAAAGCACCTTTGAGAC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTTFDNIPHNDEIDDIQDFNQYPDASGHFGIHGGRFVSETLMAALEELETLYYQVKQDPAFWQEYHNDLVNYVGRPTPLY
HAKRLSDEIGGAQIYFKREDLNHTGAHKVNNTIGQALLAKMSGKKRIIAETGAGQHGVATATIAARLGLECIIYMGADDV
ERQKMNVYRMRLLGAKVVAVESGSRTLKDAMNEAMRDWVTNVDTTYYIIGTVAGPHPYPLLVRDFQAIIGKEARLQHLEK
TGKLPDALVACVGGGSNAIGLFYEFLNDTDVKMYGVEATGDGIETGRHSAPLAAGRVGVLHGNRTYLMADDDGQILETHS
ISAGLDYPGVGPEHSFLKDVKRVEYVGCTDKEALHGFHEVTRKEGIIPALESSHAVAYALQLAKTMSPEQSIIVNMSGRG
DKDLHSVMKAEGIEL

Sequences:

>Translated_415_residues
MTTFDNIPHNDEIDDIQDFNQYPDASGHFGIHGGRFVSETLMAALEELETLYYQVKQDPAFWQEYHNDLVNYVGRPTPLY
HAKRLSDEIGGAQIYFKREDLNHTGAHKVNNTIGQALLAKMSGKKRIIAETGAGQHGVATATIAARLGLECIIYMGADDV
ERQKMNVYRMRLLGAKVVAVESGSRTLKDAMNEAMRDWVTNVDTTYYIIGTVAGPHPYPLLVRDFQAIIGKEARLQHLEK
TGKLPDALVACVGGGSNAIGLFYEFLNDTDVKMYGVEATGDGIETGRHSAPLAAGRVGVLHGNRTYLMADDDGQILETHS
ISAGLDYPGVGPEHSFLKDVKRVEYVGCTDKEALHGFHEVTRKEGIIPALESSHAVAYALQLAKTMSPEQSIIVNMSGRG
DKDLHSVMKAEGIEL
>Mature_414_residues
TTFDNIPHNDEIDDIQDFNQYPDASGHFGIHGGRFVSETLMAALEELETLYYQVKQDPAFWQEYHNDLVNYVGRPTPLYH
AKRLSDEIGGAQIYFKREDLNHTGAHKVNNTIGQALLAKMSGKKRIIAETGAGQHGVATATIAARLGLECIIYMGADDVE
RQKMNVYRMRLLGAKVVAVESGSRTLKDAMNEAMRDWVTNVDTTYYIIGTVAGPHPYPLLVRDFQAIIGKEARLQHLEKT
GKLPDALVACVGGGSNAIGLFYEFLNDTDVKMYGVEATGDGIETGRHSAPLAAGRVGVLHGNRTYLMADDDGQILETHSI
SAGLDYPGVGPEHSFLKDVKRVEYVGCTDKEALHGFHEVTRKEGIIPALESSHAVAYALQLAKTMSPEQSIIVNMSGRGD
KDLHSVMKAEGIEL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=389, Percent_Identity=55.012853470437, Blast_Score=437, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321412, Length=396, Percent_Identity=56.5656565656566, Blast_Score=476, Evalue=1e-135,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 45532; Mature: 45401

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFDNIPHNDEIDDIQDFNQYPDASGHFGIHGGRFVSETLMAALEELETLYYQVKQDPA
CCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
FWQEYHNDLVNYVGRPTPLYHAKRLSDEIGGAQIYFKREDLNHTGAHKVNNTIGQALLAK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH
MSGKKRIIAETGAGQHGVATATIAARLGLECIIYMGADDVERQKMNVYRMRLLGAKVVAV
HCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEE
ESGSRTLKDAMNEAMRDWVTNVDTTYYIIGTVAGPHPYPLLVRDFQAIIGKEARLQHLEK
ECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHH
TGKLPDALVACVGGGSNAIGLFYEFLNDTDVKMYGVEATGDGIETGRHSAPLAAGRVGVL
HCCCCHHHHEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEE
HGNRTYLMADDDGQILETHSISAGLDYPGVGPEHSFLKDVKRVEYVGCTDKEALHGFHEV
ECCEEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
TRKEGIIPALESSHAVAYALQLAKTMSPEQSIIVNMSGRGDKDLHSVMKAEGIEL
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTFDNIPHNDEIDDIQDFNQYPDASGHFGIHGGRFVSETLMAALEELETLYYQVKQDPA
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
FWQEYHNDLVNYVGRPTPLYHAKRLSDEIGGAQIYFKREDLNHTGAHKVNNTIGQALLAK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH
MSGKKRIIAETGAGQHGVATATIAARLGLECIIYMGADDVERQKMNVYRMRLLGAKVVAV
HCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEE
ESGSRTLKDAMNEAMRDWVTNVDTTYYIIGTVAGPHPYPLLVRDFQAIIGKEARLQHLEK
ECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHH
TGKLPDALVACVGGGSNAIGLFYEFLNDTDVKMYGVEATGDGIETGRHSAPLAAGRVGVL
HCCCCHHHHEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEE
HGNRTYLMADDDGQILETHSISAGLDYPGVGPEHSFLKDVKRVEYVGCTDKEALHGFHEV
ECCEEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
TRKEGIIPALESSHAVAYALQLAKTMSPEQSIIVNMSGRGDKDLHSVMKAEGIEL
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA