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The map label for this gene is mutT [C]

Identifier: 148643429

GI number: 148643429

Start: 1389755

End: 1390159

Strand: Reverse

Name: mutT [C]

Synonym: Msm_1369

Alternate gene names: 148643429

Gene position: 1390159-1389755 (Counterclockwise)

Preceding gene: 148643433

Following gene: 148643427

Centisome position: 75.02

GC content: 33.33

Gene sequence:

>405_bases
ATGGATAAACCTTATGGACTTACAATGAGAGGAATAGTCAAAAACAGCAATGACGAAATATTAATACTTAGAAGACATCC
AAAATCCAGAACAAACCCCCACAAATGGGAATTACCCGGAGGAAAGGTAGACCCCGGAGAATTTTTCGATGAAGCATTAG
TACGTGAAATAAAAGAAGAGACTAATTTGGATGGAGCAGTTGGTGACTTCTACGAAGCAATACAAGATGATTATGTCCAT
AAAAGAACTGTTCAAGTTGTTATGTATTTAAAAAATATCACTGGAGATGTAGCTATCAGTGATGAACATGATGAGTGGAT
GTGGGCCAATTTAGAAAAAATAAAAACATTGGAATTATCAACAGCATTTGAAAAAGTTTTAAAAAAGAAAAATTGGAAAA
TTTAA

Upstream 100 bases:

>100_bases
TTATAAATATTACTCTTGAAAAAATACTGAAAATGAACAAAATAAATAGGCAAAATAATTAAATATTCCAATGGCAAAGA
GTAAAACAGGTGAATTTAAA

Downstream 100 bases:

>100_bases
AGAGCTTTGTCTAAAGCTTCAACAAATTTATCAATTTCCTCATTGGTAATTATAAGAGGCGGAACAAATCTTAAAACATT
GCCTGCAGTGCAGTTAATTA

Product: MutT-related protein NUDIX family

Products: 8-Oxo-Dgmp; Pyrophosphate. [C]

Alternate protein names: NUDIX Hydrolase; NUDIX Domain-Containing Protein; MutT-Related Protein NUDIX Family; Mutator MutT Related Protein; MutT-Related Protein; MutT/NUDIX Family Hydrolase /Pyrophosphatase; Mutator MutT Protein; Hydrolase

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MDKPYGLTMRGIVKNSNDEILILRRHPKSRTNPHKWELPGGKVDPGEFFDEALVREIKEETNLDGAVGDFYEAIQDDYVH
KRTVQVVMYLKNITGDVAISDEHDEWMWANLEKIKTLELSTAFEKVLKKKNWKI

Sequences:

>Translated_134_residues
MDKPYGLTMRGIVKNSNDEILILRRHPKSRTNPHKWELPGGKVDPGEFFDEALVREIKEETNLDGAVGDFYEAIQDDYVH
KRTVQVVMYLKNITGDVAISDEHDEWMWANLEKIKTLELSTAFEKVLKKKNWKI
>Mature_134_residues
MDKPYGLTMRGIVKNSNDEILILRRHPKSRTNPHKWELPGGKVDPGEFFDEALVREIKEETNLDGAVGDFYEAIQDDYVH
KRTVQVVMYLKNITGDVAISDEHDEWMWANLEKIKTLELSTAFEKVLKKKNWKI

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 15616; Mature: 15616

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKPYGLTMRGIVKNSNDEILILRRHPKSRTNPHKWELPGGKVDPGEFFDEALVREIKEE
CCCCCCCEEEHEEECCCCCEEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHH
TNLDGAVGDFYEAIQDDYVHKRTVQVVMYLKNITGDVAISDEHDEWMWANLEKIKTLELS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
TAFEKVLKKKNWKI
HHHHHHHHHCCCCC
>Mature Secondary Structure
MDKPYGLTMRGIVKNSNDEILILRRHPKSRTNPHKWELPGGKVDPGEFFDEALVREIKEE
CCCCCCCEEEHEEECCCCCEEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHH
TNLDGAVGDFYEAIQDDYVHKRTVQVVMYLKNITGDVAISDEHDEWMWANLEKIKTLELS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
TAFEKVLKKKNWKI
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 8-Oxo-Dgtp; H2O [C]

Specific reaction: 8-Oxo-Dgtp + H2O = 8-Oxo-Dgmp + Pyrophosphate. [C]

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA