Click here to switch to the map view.

The map label for this gene is ade

Identifier: 148642934

GI number: 148642934

Start: 829183

End: 830898

Strand: Reverse

Name: ade

Synonym: Msm_0874

Alternate gene names: 148642934

Gene position: 830898-829183 (Counterclockwise)

Preceding gene: 148642935

Following gene: 148642932

Centisome position: 44.84

GC content: 33.97

Gene sequence:

>1716_bases
ATGCAATTCAGTGCATATATGTTAGACGTTATAACTGATTCAATTTATCCTGCACGTATTTCAGTTGAAGGCGGATTTTT
TAAAGAGATAGTTCCAATTGTCATTAATGACGACAGTGAATTGGATATTTCAGGGATTATTCTTCCGGGATTTATTGATT
CTCATATTCATATTGAAAGTACCATGCTTACTCCTGCACAGTTTGCAAAACTGGCTGTAAGGTTCGGTACTACTTCAGTT
GTTTGTGATCCTCATGAAATAGCTAATGTTGCAGGTACTGACGGGATAGATTTCATGATTGAAAATTCAAAATCTGTTCC
TTTTAATTTTTATTTTTCAATTCCATCATGTGTTCCTGCAACCTGTTTTGAAACATCAGGAGCTATTTTGGACAGCGAAA
CTATCGGAGAACTTCTTAAAAAAGATGAAGCTGTTGCACTTGGTGAAATGATGAATTTTCCAGGTGTGATAAATGGGGAT
GGGGAAGTTTTGGCCAAACTGGAAAAAGCAAAAGAACTTGGAAAACCTATAGACGGTCATGCGCCTCTGCTTTCAGGAAA
AGATTTGGATAAATATATGGCTGAACATATATCTACTGATCATGAATGCAGTAATTTTGCAGAAGCTATTGAAAAAAAAG
AAAAAGGTATGAAAATAATGGTTCGTGAGGGGTCTTCTGCTAAAAATATGGAAGCTCTTTTTGATTTTAGCGACAGGTTA
GACTACTGGAAAAATCACGAAAGTTTCGGAAAAATGCCCAATGAAGTTCTGGAAAAAAGAATACATCTTCCTATTTTTGA
TTTTATAGTAAGTGATGACAAACACACCACTGACTTAATTAAAGGTCATTTAAATGAATCCATTAAAAAAGCCATTGATT
TGGAAGTCAGTCCGATAAGTGCTATTGAAATGGTTACAGTTAATCCGTCAACACATTATAATTTAAATACTGGTGCTATT
GTAAAAGGAATGCAGGCAGATTATGTTGTTGTAGATAATCTGAATGATTTGAATATTTTAAAGACATATGTTGCAGGCAA
ATGTGTTTTTGATGGTGAAAATGTTTTATTTGATGTGGAAGAAACGGAATTCAAAAATACATTTGATGTTTCCAAAAAAG
AATCTGAAGATTTTGAAATTTCATGTGATGAACCTTCAGCAGATGTTAATGTAATTCGATGTTTCAACGGGGAATTAATA
ACTGAAGCTGAAAGTGCAACATTGGAAACTAAAAAAGGATTTGTACAGCCTGATTTGGAAGAGGATATTTTAAAAATAGC
TGTTGTTGAGCGTTATGGTGGAAATTCAATAGCCAACGGATTTATAACAGGATTCAATCTTAAAAAAGGGGCAATAGCCT
CTTCTGTAGCTCATGATTCCCATAATATTGTAGTTGTAGGAACAAATAGTGAGGACATGGCAAATGCAGTCAACTGTTTA
ATTGATAATGAAGGCGGTTTTGCTATTGTTGACGGTGATTTTGAAGATTCTTTGGCATTGCCTATTGCAGGATTGATGAC
TAATGAAGACAGTCATGAAGTAGCTGAAAAATTAGAGAAATTGCATAAAACAGCTGCTGATTTCGGATGCAAACTGGATT
CTCCGTTTATGACCATGTCATTTATGGCTCTTTTGGTAATTCCAGCTATCAAAATATCTGATAAAGGTTTATTTGACTGT
ATAAACTTTGAATTTATTGATGTAATTAAAAATTAG

Upstream 100 bases:

>100_bases
CAAATTATCTGACAGGGGAAGTGCTCAGGTAGTTAGTATTGTAACAGATATTGGTACATTTTTACCTCTTTTATATGAAT
CCCTACATGAAAGTGATTAG

Downstream 100 bases:

>100_bases
GGTGAATACCCTTTTTTTATTAATTCTTTTTTTATTTCATGAATTGCTTTTTGCTCTTCTTTTGATCCGACTTTATTTAT
TACTCTTTTTGCTTCCCTAA

Product: adenine deaminase, AdeC

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MQFSAYMLDVITDSIYPARISVEGGFFKEIVPIVINDDSELDISGIILPGFIDSHIHIESTMLTPAQFAKLAVRFGTTSV
VCDPHEIANVAGTDGIDFMIENSKSVPFNFYFSIPSCVPATCFETSGAILDSETIGELLKKDEAVALGEMMNFPGVINGD
GEVLAKLEKAKELGKPIDGHAPLLSGKDLDKYMAEHISTDHECSNFAEAIEKKEKGMKIMVREGSSAKNMEALFDFSDRL
DYWKNHESFGKMPNEVLEKRIHLPIFDFIVSDDKHTTDLIKGHLNESIKKAIDLEVSPISAIEMVTVNPSTHYNLNTGAI
VKGMQADYVVVDNLNDLNILKTYVAGKCVFDGENVLFDVEETEFKNTFDVSKKESEDFEISCDEPSADVNVIRCFNGELI
TEAESATLETKKGFVQPDLEEDILKIAVVERYGGNSIANGFITGFNLKKGAIASSVAHDSHNIVVVGTNSEDMANAVNCL
IDNEGGFAIVDGDFEDSLALPIAGLMTNEDSHEVAEKLEKLHKTAADFGCKLDSPFMTMSFMALLVIPAIKISDKGLFDC
INFEFIDVIKN

Sequences:

>Translated_571_residues
MQFSAYMLDVITDSIYPARISVEGGFFKEIVPIVINDDSELDISGIILPGFIDSHIHIESTMLTPAQFAKLAVRFGTTSV
VCDPHEIANVAGTDGIDFMIENSKSVPFNFYFSIPSCVPATCFETSGAILDSETIGELLKKDEAVALGEMMNFPGVINGD
GEVLAKLEKAKELGKPIDGHAPLLSGKDLDKYMAEHISTDHECSNFAEAIEKKEKGMKIMVREGSSAKNMEALFDFSDRL
DYWKNHESFGKMPNEVLEKRIHLPIFDFIVSDDKHTTDLIKGHLNESIKKAIDLEVSPISAIEMVTVNPSTHYNLNTGAI
VKGMQADYVVVDNLNDLNILKTYVAGKCVFDGENVLFDVEETEFKNTFDVSKKESEDFEISCDEPSADVNVIRCFNGELI
TEAESATLETKKGFVQPDLEEDILKIAVVERYGGNSIANGFITGFNLKKGAIASSVAHDSHNIVVVGTNSEDMANAVNCL
IDNEGGFAIVDGDFEDSLALPIAGLMTNEDSHEVAEKLEKLHKTAADFGCKLDSPFMTMSFMALLVIPAIKISDKGLFDC
INFEFIDVIKN
>Mature_571_residues
MQFSAYMLDVITDSIYPARISVEGGFFKEIVPIVINDDSELDISGIILPGFIDSHIHIESTMLTPAQFAKLAVRFGTTSV
VCDPHEIANVAGTDGIDFMIENSKSVPFNFYFSIPSCVPATCFETSGAILDSETIGELLKKDEAVALGEMMNFPGVINGD
GEVLAKLEKAKELGKPIDGHAPLLSGKDLDKYMAEHISTDHECSNFAEAIEKKEKGMKIMVREGSSAKNMEALFDFSDRL
DYWKNHESFGKMPNEVLEKRIHLPIFDFIVSDDKHTTDLIKGHLNESIKKAIDLEVSPISAIEMVTVNPSTHYNLNTGAI
VKGMQADYVVVDNLNDLNILKTYVAGKCVFDGENVLFDVEETEFKNTFDVSKKESEDFEISCDEPSADVNVIRCFNGELI
TEAESATLETKKGFVQPDLEEDILKIAVVERYGGNSIANGFITGFNLKKGAIASSVAHDSHNIVVVGTNSEDMANAVNCL
IDNEGGFAIVDGDFEDSLALPIAGLMTNEDSHEVAEKLEKLHKTAADFGCKLDSPFMTMSFMALLVIPAIKISDKGLFDC
INFEFIDVIKN

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=530, Percent_Identity=33.7735849056604, Blast_Score=291, Evalue=8e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_METS3 (A5ULK1)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273447.1
- ProteinModelPortal:   A5ULK1
- STRING:   A5ULK1
- GeneID:   5217333
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0874
- eggNOG:   arNOG05049
- HOGENOM:   HBG725357
- OMA:   GKIITEH
- ProtClustDB:   CLSK798019
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 62634; Mature: 62634

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSAYMLDVITDSIYPARISVEGGFFKEIVPIVINDDSELDISGIILPGFIDSHIHIES
CCCHHHHHHHHHCCCCCEEEEECCCCHHCEEEEEECCCCCCEEEEEEECCCCCCCEEEEE
TMLTPAQFAKLAVRFGTTSVVCDPHEIANVAGTDGIDFMIENSKSVPFNFYFSIPSCVPA
EECCHHHHHHHHHEECCEEEEECHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCCC
TCFETSGAILDSETIGELLKKDEAVALGEMMNFPGVINGDGEVLAKLEKAKELGKPIDGH
HHHCCCCCEECHHHHHHHHHCCCHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCCCCC
APLLSGKDLDKYMAEHISTDHECSNFAEAIEKKEKGMKIMVREGSSAKNMEALFDFSDRL
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCHHHHH
DYWKNHESFGKMPNEVLEKRIHLPIFDFIVSDDKHTTDLIKGHLNESIKKAIDLEVSPIS
HHHCCCHHHCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
AIEMVTVNPSTHYNLNTGAIVKGMQADYVVVDNLNDLNILKTYVAGKCVFDGENVLFDVE
EEEEEEECCCCCEECCCCCEEECCCCCEEEEECCCCHHHHHHHHCCEEEECCCCEEEECC
ETEFKNTFDVSKKESEDFEISCDEPSADVNVIRCFNGELITEAESATLETKKGFVQPDLE
HHCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCEEECCCCCEEHHHCCCCCCCHH
EDILKIAVVERYGGNSIANGFITGFNLKKGAIASSVAHDSHNIVVVGTNSEDMANAVNCL
HHHHEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHCCCCCCEEEEECCCHHHHHHEEEE
IDNEGGFAIVDGDFEDSLALPIAGLMTNEDSHEVAEKLEKLHKTAADFGCKLDSPFMTMS
EECCCCEEEECCCCCCCCCCCEEHEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
FMALLVIPAIKISDKGLFDCINFEFIDVIKN
HHHHHHHCCEEECCCCCEEECCCEEEHHHCC
>Mature Secondary Structure
MQFSAYMLDVITDSIYPARISVEGGFFKEIVPIVINDDSELDISGIILPGFIDSHIHIES
CCCHHHHHHHHHCCCCCEEEEECCCCHHCEEEEEECCCCCCEEEEEEECCCCCCCEEEEE
TMLTPAQFAKLAVRFGTTSVVCDPHEIANVAGTDGIDFMIENSKSVPFNFYFSIPSCVPA
EECCHHHHHHHHHEECCEEEEECHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCCC
TCFETSGAILDSETIGELLKKDEAVALGEMMNFPGVINGDGEVLAKLEKAKELGKPIDGH
HHHCCCCCEECHHHHHHHHHCCCHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCCCCC
APLLSGKDLDKYMAEHISTDHECSNFAEAIEKKEKGMKIMVREGSSAKNMEALFDFSDRL
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCHHHHH
DYWKNHESFGKMPNEVLEKRIHLPIFDFIVSDDKHTTDLIKGHLNESIKKAIDLEVSPIS
HHHCCCHHHCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
AIEMVTVNPSTHYNLNTGAIVKGMQADYVVVDNLNDLNILKTYVAGKCVFDGENVLFDVE
EEEEEEECCCCCEECCCCCEEECCCCCEEEEECCCCHHHHHHHHCCEEEECCCCEEEECC
ETEFKNTFDVSKKESEDFEISCDEPSADVNVIRCFNGELITEAESATLETKKGFVQPDLE
HHCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCEEECCCCCEEHHHCCCCCCCHH
EDILKIAVVERYGGNSIANGFITGFNLKKGAIASSVAHDSHNIVVVGTNSEDMANAVNCL
HHHHEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHCCCCCCEEEEECCCHHHHHHEEEE
IDNEGGFAIVDGDFEDSLALPIAGLMTNEDSHEVAEKLEKLHKTAADFGCKLDSPFMTMS
EECCCCEEEECCCCCCCCCCCEEHEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
FMALLVIPAIKISDKGLFDCINFEFIDVIKN
HHHHHHHCCEEECCCCCEEECCCEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA