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The map label for this gene is glmS [H]

Identifier: 148642932

GI number: 148642932

Start: 827438

End: 828445

Strand: Reverse

Name: glmS [H]

Synonym: Msm_0872

Alternate gene names: 148642932

Gene position: 828445-827438 (Counterclockwise)

Preceding gene: 148642934

Following gene: 148642931

Centisome position: 44.7

GC content: 31.65

Gene sequence:

>1008_bases
ATGAACTATAAAATGTATGATGAAATGATGGAGCAACCTGATTCACTTAGAAGGACATTTGCAAGCGAAATGTCTAAAAT
GGATAGTGTTTCAGAAGCTGTATCAAAAGCAGATAAAATTTATTTAATTGGTTGTGGCAGTTCTATTTCTACATGTTATA
GTGTTAGGGATGCATTGAGAATGTCCTGTGATATGAGTGTAGAAGTATTTACAGGCTATGAATTTTATTATAATAAAAAA
TTAACTGACGGAGAAAATTCAATAGCTATTTTCACATCACAATCCGGTGAAACTGCAGATACTTTAGCATCTCTTAAAAG
AGCTAATGAATATGGAATTCACACTGTTTCAATTTCTAATGAACCTGATAGTTCAATGATAAAAGAAGCTAAAACTCCAA
TTATAACACAATGTGAAAGGGAAACAGCAATTCTTGGAACTAAAACATATGTAACTCAGTTAGCCTGTCTTTATCAGATT
TTATTTAAAGGATCCAACTATGGCAAGGCAGATGAACTGTTAGATGATTTGAAACATATTCCTGATATTATTGAAGAATT
ATTAAAAACAACAGAAGAAGACAATAAAAAATTAGCTGAAGAGTTTAAGGATGAAGATATCTTCTACTGTTTAGGCAGCG
GACCTAACTTCGGCCTTTCATTTAAATTAGCTATGACTATGCTTATGGAAGGAGCAATTAAACATGCATGTCCTGTTTAC
TCTGCGGAATTTAGGCACGGTTTAATAGAACGTGCAGAAAAAGATGTTCCAATTATTTTCCTGCGTTCAGGTTTTGAATC
AGATGAAATAACTGACAAAGCTATTGAATTTTCTAAAAATTTAGAATTGAAGTCTATTGTTTATAATTTGGAAGATTATG
CAGATATCAATCTGTTATTATCTCCATTAATATTTGTAGTTCCTTTAGAATGGTTTGTTTATTATTTGGCACATTTTAAT
GGTGAAGATCCTGGTGCTACAAGACATATCGGAAAAGTCAGATATTAA

Upstream 100 bases:

>100_bases
TAATATTTACTTAATTAAAGTATCGATTTTTAAAAAACATTTTTATATGTTAATAAACAATAGTATAAGTATTATATATT
AATTTTAAGGAGTTTAAGCA

Downstream 100 bases:

>100_bases
TTTTTTTTAAAAAAAGGAGTCTGTAAAATTTTATAGGCTTATTTGTTTTTTAATTTTTTACAGTTGAACTTTCATTTTGA
TGAAATTTCATTCTAATTTT

Product: glucosamine:fructose-6-phosphate aminotransferase (isomerizing), AgaS

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNYKMYDEMMEQPDSLRRTFASEMSKMDSVSEAVSKADKIYLIGCGSSISTCYSVRDALRMSCDMSVEVFTGYEFYYNKK
LTDGENSIAIFTSQSGETADTLASLKRANEYGIHTVSISNEPDSSMIKEAKTPIITQCERETAILGTKTYVTQLACLYQI
LFKGSNYGKADELLDDLKHIPDIIEELLKTTEEDNKKLAEEFKDEDIFYCLGSGPNFGLSFKLAMTMLMEGAIKHACPVY
SAEFRHGLIERAEKDVPIIFLRSGFESDEITDKAIEFSKNLELKSIVYNLEDYADINLLLSPLIFVVPLEWFVYYLAHFN
GEDPGATRHIGKVRY

Sequences:

>Translated_335_residues
MNYKMYDEMMEQPDSLRRTFASEMSKMDSVSEAVSKADKIYLIGCGSSISTCYSVRDALRMSCDMSVEVFTGYEFYYNKK
LTDGENSIAIFTSQSGETADTLASLKRANEYGIHTVSISNEPDSSMIKEAKTPIITQCERETAILGTKTYVTQLACLYQI
LFKGSNYGKADELLDDLKHIPDIIEELLKTTEEDNKKLAEEFKDEDIFYCLGSGPNFGLSFKLAMTMLMEGAIKHACPVY
SAEFRHGLIERAEKDVPIIFLRSGFESDEITDKAIEFSKNLELKSIVYNLEDYADINLLLSPLIFVVPLEWFVYYLAHFN
GEDPGATRHIGKVRY
>Mature_335_residues
MNYKMYDEMMEQPDSLRRTFASEMSKMDSVSEAVSKADKIYLIGCGSSISTCYSVRDALRMSCDMSVEVFTGYEFYYNKK
LTDGENSIAIFTSQSGETADTLASLKRANEYGIHTVSISNEPDSSMIKEAKTPIITQCERETAILGTKTYVTQLACLYQI
LFKGSNYGKADELLDDLKHIPDIIEELLKTTEEDNKKLAEEFKDEDIFYCLGSGPNFGLSFKLAMTMLMEGAIKHACPVY
SAEFRHGLIERAEKDVPIIFLRSGFESDEITDKAIEFSKNLELKSIVYNLEDYADINLLLSPLIFVVPLEWFVYYLAHFN
GEDPGATRHIGKVRY

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=357, Percent_Identity=23.5294117647059, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI205277386, Length=355, Percent_Identity=23.3802816901408, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI87082251, Length=309, Percent_Identity=29.4498381877023, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790167, Length=355, Percent_Identity=26.7605633802817, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17532899, Length=358, Percent_Identity=22.6256983240223, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17539970, Length=360, Percent_Identity=23.0555555555556, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17532897, Length=358, Percent_Identity=22.6256983240223, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6322745, Length=367, Percent_Identity=26.158038147139, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323731, Length=307, Percent_Identity=24.4299674267101, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357745, Length=368, Percent_Identity=22.2826086956522, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 37930; Mature: 37930

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKMYDEMMEQPDSLRRTFASEMSKMDSVSEAVSKADKIYLIGCGSSISTCYSVRDALR
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
MSCDMSVEVFTGYEFYYNKKLTDGENSIAIFTSQSGETADTLASLKRANEYGIHTVSISN
HHCCCEEEEEECEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECC
EPDSSMIKEAKTPIITQCERETAILGTKTYVTQLACLYQILFKGSNYGKADELLDDLKHI
CCCHHHHHHHCCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
PDIIEELLKTTEEDNKKLAEEFKDEDIFYCLGSGPNFGLSFKLAMTMLMEGAIKHACPVY
HHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCH
SAEFRHGLIERAEKDVPIIFLRSGFESDEITDKAIEFSKNLELKSIVYNLEDYADINLLL
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SPLIFVVPLEWFVYYLAHFNGEDPGATRHIGKVRY
HHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MNYKMYDEMMEQPDSLRRTFASEMSKMDSVSEAVSKADKIYLIGCGSSISTCYSVRDALR
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
MSCDMSVEVFTGYEFYYNKKLTDGENSIAIFTSQSGETADTLASLKRANEYGIHTVSISN
HHCCCEEEEEECEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECC
EPDSSMIKEAKTPIITQCERETAILGTKTYVTQLACLYQILFKGSNYGKADELLDDLKHI
CCCHHHHHHHCCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
PDIIEELLKTTEEDNKKLAEEFKDEDIFYCLGSGPNFGLSFKLAMTMLMEGAIKHACPVY
HHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCH
SAEFRHGLIERAEKDVPIIFLRSGFESDEITDKAIEFSKNLELKSIVYNLEDYADINLLL
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SPLIFVVPLEWFVYYLAHFNGEDPGATRHIGKVRY
HHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]