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The map label for this gene is pelA

Identifier: 148642700

GI number: 148642700

Start: 618552

End: 619613

Strand: Reverse

Name: pelA

Synonym: Msm_0640

Alternate gene names: 148642700

Gene position: 619613-618552 (Counterclockwise)

Preceding gene: 148642706

Following gene: 148642699

Centisome position: 33.44

GC content: 34.65

Gene sequence:

>1062_bases
ATGAAAATTGTAAAACAGGATAAAAAAGAAGGAATTGTGACATTAGTTCCAGAAACTCTTGATGATTTGTGGCATTTGTC
TCATATTGTAGAGGTTGGAGACAGTGTATCTTCCAAAACTACCAGACGTATTCAGGACAATACTGGAGATAAATTAAGAA
GTGACAGAGGGGTCAAAAAAACATTTACTTTAAGAATTGATGTTGAAAATATTACTTTTCATATTTTTACCGGAAAATTA
AGGCTTACCGGGGTAATTACAAAAGGTCCGGAAGATCTTATTCCTTTAGGTTCACACCATACAGTTGAAGTTAAACTTAA
CACTCCAATAACCATTAAAAAGGAAAAGTGGGCAAACTGGGCACTAAAAAGACTCAATCAGGCTATTGAAGCATCTAAAA
AATTAGCTGCAATCATTGTTCTTTTGGAGGATGACACAGCTACTTTAGGTTTGATGAGACAGTTCGGTATTGAATATTAT
GGTCCGATTAAAGGTTCTGTTTCAGGAAAGCGCATTGTGGATAAAAACAGATCAAAGGCAATCGCCCAGTTTTATGAAAA
GGTCATTGAATCAGTCAATAAATTCCATGATATTCAAAATATTGTAGTTGCAGGACCGGGCTTTGTTAAAAATGATTTTT
ATGATTATATTAAAAATAAGCATAAGGATTTAGCTGATAAGGCAATTATTGAAAGTACAGGTTCTGGAGGAAGGGTTGGA
ATTCATGAAGTTCTTAAAAAAGGGACTGTTGAGAAACTAACTGTGGAAAATAGGGTAGCCAGTGAAATGGTTGCCATCAA
CAATCTTCTTGAAGAAATAGGTAAGAATTCATCTAAAGTGGCTTATGGTGAAAAAGAAACTGTTAAAGCAATAAACCTTG
GTGCAGTTAAACAGTTATTGGTACTGGATTCTGCAGTAGCTATTAATGATATGGGAAATTTAATGGACATGGTTGAAAAT
ATGAATGGTGAAGTAATGGTTATCAGTAGCCAGCATGAAGGTGGGGAGCAACTTAAAGGTTTGGGTAGTATGGCAGCTAT
TTTAAGATATGAAATAGCTTAA

Upstream 100 bases:

>100_bases
GGTTTTTCCCAAACCGTCACTTCCGCCTATTATTCCAACTTTCATTTCAATCATTAATAATTTAAGTTATCAGATATATA
AATAATTTAGATGTGGAAAT

Downstream 100 bases:

>100_bases
TTTCTTTTTTAAATAAAGATTTATATAATATTAATTATTATAAGTTATAACTAGTAACAATATTAAAAAATGACTATATT
TTTTAATGAAAAACTGTGAT

Product: cell division protein (RNA-binding), PelA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKIVKQDKKEGIVTLVPETLDDLWHLSHIVEVGDSVSSKTTRRIQDNTGDKLRSDRGVKKTFTLRIDVENITFHIFTGKL
RLTGVITKGPEDLIPLGSHHTVEVKLNTPITIKKEKWANWALKRLNQAIEASKKLAAIIVLLEDDTATLGLMRQFGIEYY
GPIKGSVSGKRIVDKNRSKAIAQFYEKVIESVNKFHDIQNIVVAGPGFVKNDFYDYIKNKHKDLADKAIIESTGSGGRVG
IHEVLKKGTVEKLTVENRVASEMVAINNLLEEIGKNSSKVAYGEKETVKAINLGAVKQLLVLDSAVAINDMGNLMDMVEN
MNGEVMVISSQHEGGEQLKGLGSMAAILRYEIA

Sequences:

>Translated_353_residues
MKIVKQDKKEGIVTLVPETLDDLWHLSHIVEVGDSVSSKTTRRIQDNTGDKLRSDRGVKKTFTLRIDVENITFHIFTGKL
RLTGVITKGPEDLIPLGSHHTVEVKLNTPITIKKEKWANWALKRLNQAIEASKKLAAIIVLLEDDTATLGLMRQFGIEYY
GPIKGSVSGKRIVDKNRSKAIAQFYEKVIESVNKFHDIQNIVVAGPGFVKNDFYDYIKNKHKDLADKAIIESTGSGGRVG
IHEVLKKGTVEKLTVENRVASEMVAINNLLEEIGKNSSKVAYGEKETVKAINLGAVKQLLVLDSAVAINDMGNLMDMVEN
MNGEVMVISSQHEGGEQLKGLGSMAAILRYEIA
>Mature_353_residues
MKIVKQDKKEGIVTLVPETLDDLWHLSHIVEVGDSVSSKTTRRIQDNTGDKLRSDRGVKKTFTLRIDVENITFHIFTGKL
RLTGVITKGPEDLIPLGSHHTVEVKLNTPITIKKEKWANWALKRLNQAIEASKKLAAIIVLLEDDTATLGLMRQFGIEYY
GPIKGSVSGKRIVDKNRSKAIAQFYEKVIESVNKFHDIQNIVVAGPGFVKNDFYDYIKNKHKDLADKAIIESTGSGGRVG
IHEVLKKGTVEKLTVENRVASEMVAINNLLEEIGKNSSKVAYGEKETVKAINLGAVKQLLVLDSAVAINDMGNLMDMVEN
MNGEVMVISSQHEGGEQLKGLGSMAAILRYEIA

Specific function: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has end

COG id: COG1537

COG function: function code R; Predicted RNA-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic release factor 1 family. Pelota subfamily

Homologues:

Organism=Homo sapiens, GI31880783, Length=373, Percent_Identity=28.1501340482574, Blast_Score=153, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17554648, Length=360, Percent_Identity=26.9444444444444, Blast_Score=121, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6324327, Length=370, Percent_Identity=27.027027027027, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136914, Length=363, Percent_Identity=29.4765840220386, Blast_Score=162, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PELO_METS3 (A5UKW7)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273213.1
- STRING:   A5UKW7
- GeneID:   5215932
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0640
- eggNOG:   arNOG04486
- HOGENOM:   HBG646058
- OMA:   MKLVRKD
- ProtClustDB:   CLSK798231
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01853
- InterPro:   IPR005140
- InterPro:   IPR005141
- InterPro:   IPR005142
- InterPro:   IPR004405
- PANTHER:   PTHR10853
- TIGRFAMs:   TIGR00111

Pfam domain/function: PF03463 eRF1_1; PF03464 eRF1_2; PF03465 eRF1_3

EC number: NA

Molecular weight: Translated: 39030; Mature: 39030

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVKQDKKEGIVTLVPETLDDLWHLSHIVEVGDSVSSKTTRRIQDNTGDKLRSDRGVKK
CCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHCCCCCCE
TFTLRIDVENITFHIFTGKLRLTGVITKGPEDLIPLGSHHTVEVKLNTPITIKKEKWANW
EEEEEEEEEEEEEEEEECEEEEEEEEECCCHHCCCCCCCEEEEEEECCCEEEEHHHHHHH
ALKRLNQAIEASKKLAAIIVLLEDDTATLGLMRQFGIEYYGPIKGSVSGKRIVDKNRSKA
HHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCEECCCCCCCCCCCHHCCCHHHH
IAQFYEKVIESVNKFHDIQNIVVAGPGFVKNDFYDYIKNKHKDLADKAIIESTGSGGRVG
HHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IHEVLKKGTVEKLTVENRVASEMVAINNLLEEIGKNSSKVAYGEKETVKAINLGAVKQLL
HHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHH
VLDSAVAINDMGNLMDMVENMNGEVMVISSQHEGGEQLKGLGSMAAILRYEIA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIVKQDKKEGIVTLVPETLDDLWHLSHIVEVGDSVSSKTTRRIQDNTGDKLRSDRGVKK
CCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHCCCCCCE
TFTLRIDVENITFHIFTGKLRLTGVITKGPEDLIPLGSHHTVEVKLNTPITIKKEKWANW
EEEEEEEEEEEEEEEEECEEEEEEEEECCCHHCCCCCCCEEEEEEECCCEEEEHHHHHHH
ALKRLNQAIEASKKLAAIIVLLEDDTATLGLMRQFGIEYYGPIKGSVSGKRIVDKNRSKA
HHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCEECCCCCCCCCCCHHCCCHHHH
IAQFYEKVIESVNKFHDIQNIVVAGPGFVKNDFYDYIKNKHKDLADKAIIESTGSGGRVG
HHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IHEVLKKGTVEKLTVENRVASEMVAINNLLEEIGKNSSKVAYGEKETVKAINLGAVKQLL
HHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHH
VLDSAVAINDMGNLMDMVENMNGEVMVISSQHEGGEQLKGLGSMAAILRYEIA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA