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The map label for this gene is expZ [H]

Identifier: 148380816

GI number: 148380816

Start: 3036690

End: 3038168

Strand: Reverse

Name: expZ [H]

Synonym: CBO2858

Alternate gene names: 148380816

Gene position: 3038168-3036690 (Counterclockwise)

Preceding gene: 148380817

Following gene: 148380815

Centisome position: 78.16

GC content: 31.91

Gene sequence:

>1479_bases
ATGTCTTTAATAAATGTTACAAACCTAACCTTTGCTTATGAAGGTAGCTATGATAATATTTTTGAAAATGTAAGTTTTCA
AATTGATACAGATTGGAAATTGGGGTTTACTGGAAGAAATGGAAGAGGAAAGACTACTTTTCTAAGTCTTTTGCTTGGGA
AATACGAATATAATGGAAACATTTCAGCTGATGTGACTTTTGAATATTTTCCTTATGAGGTGCAGGAGCAGAGCAATTTC
ACCATAGATATCATAAGGGAGATTAGTCCAAATTCAATGGATTGGGAAATAGTAAAAGAATTATCTTTGTTAGATATGGA
CTATGATGCTTTATATAGACAGTTTTATACACTATCTAAAGGAGAGCAGACTAAAGCACTGTTGGCTGCTATGTTTTTAA
AGGAGAGCTCCTTCTTGCTTATTGATGAGCCTACCAATCATTTGGATGCTGAAGCTAGGCAAAAACTAAGTAATTACTTG
AAAAAAAAGAAAGGATTTATTCTGATTTCACATGATAGGTCTTTTTTGGATAATTGTGTTGACCATATCCTGTCTATTAA
TAAAACTAATATTGAAATACAAAAAGGAAATTTTTCTTCATGGTGGAGAAACAAAGAATTACAAGATGGTTTTGAGCTAG
CAGAAAACGAAAAATTGAAAAAAGATATTAACAGACTTTCAAGCTCGGCAAAACGTACATCTACGTGGTCAGATAGTGTT
GAAGGCAGCAAGCATGGAACTACCAATTCTGGGAGCAAATTAGATAAAGGATATGTTGGACATAAAGCTGCAAAAATGAT
GAAGCGTGCTAAAAATATAGAAGCTAGACAACAAAACATGATTGAGGAAAAATCAAAGCTTCTTAAAAATATTGAATCTA
ATGAAAGTTTAAAAATAGTACCGCTTACTTTCCATGATAAAAAGCTTGTAGAACTTACAGATGTTGCAATTGAATATGAT
GATAGAATTGTCTGTGAAGGAGTAAGCTTCACTATAGAGCAAGGTGAAAGAATTGCTATTCAAGGAAAGAATGGTAGCGG
AAAATCAAGTATATTGAAATTAATTTATGGAGAAGACATCCCCCATAGTGGAATTGTAAGAAAGAATAATAAGTTAATCA
TTTCGTATGTTTCACAAGATACTTCAGATTTATATGGTAACTTATCTGAATATGCAGATAAACACTGTATTGACGAGAGT
TTATTTAAATCGATACTTAGAAAGCTTGATTTTTCAAGAGAACAGTTTGAAAAGAATATCGAGGATTTTAGTGGAGGACA
GAAAAAAAAGGTATTGATTGCCAAAAGTTTGTGTGAACGGGCACATTTGTATATTTGGGATGAACCGCTGAATTTTATTG
ATGTCATTTCTCGTATGCAGATTGAGAAATTGTTAATTGAACATGAACCTACAATTTTGTTTATTGAGCATGATAGTGCA
TTTTGTGAAAATGTTGCAACAAAAACAATAAAATTGTAA

Upstream 100 bases:

>100_bases
AGTCGGATATTGCAGGCGACACTTATATGGAGTAATAACAAGGTCGCCTATTGTTCCGACTTTGTTATTTATACTATTAA
ATACAGAGGAGGATAAAAAT

Downstream 100 bases:

>100_bases
AGGCAGAAATGGCGATTAATATGTTTAATGGGAATATAAAAGTAACACACAATAGGCTCCATGCAAAGCCAGATGTTTTG
GGCGACGCTTGCATGGAGTA

Product: drug resistance ABC transporter, RA2 family, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLSLLLGKYEYNGNISADVTFEYFPYEVQEQSNF
TIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSKGEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYL
KKKKGFILISHDRSFLDNCVDHILSINKTNIEIQKGNFSSWWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIVPLTFHDKKLVELTDVAIEYD
DRIVCEGVSFTIEQGERIAIQGKNGSGKSSILKLIYGEDIPHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHCIDES
LFKSILRKLDFSREQFEKNIEDFSGGQKKKVLIAKSLCERAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
FCENVATKTIKL

Sequences:

>Translated_492_residues
MSLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLSLLLGKYEYNGNISADVTFEYFPYEVQEQSNF
TIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSKGEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYL
KKKKGFILISHDRSFLDNCVDHILSINKTNIEIQKGNFSSWWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIVPLTFHDKKLVELTDVAIEYD
DRIVCEGVSFTIEQGERIAIQGKNGSGKSSILKLIYGEDIPHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHCIDES
LFKSILRKLDFSREQFEKNIEDFSGGQKKKVLIAKSLCERAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
FCENVATKTIKL
>Mature_491_residues
SLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLSLLLGKYEYNGNISADVTFEYFPYEVQEQSNFT
IDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSKGEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYLK
KKKGFILISHDRSFLDNCVDHILSINKTNIEIQKGNFSSWWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSVE
GSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIVPLTFHDKKLVELTDVAIEYDD
RIVCEGVSFTIEQGERIAIQGKNGSGKSSILKLIYGEDIPHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHCIDESL
FKSILRKLDFSREQFEKNIEDFSGGQKKKVLIAKSLCERAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSAF
CENVATKTIKL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27881506, Length=529, Percent_Identity=24.3856332703214, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI10947137, Length=529, Percent_Identity=24.3856332703214, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI148612853, Length=535, Percent_Identity=23.7383177570093, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI10947135, Length=400, Percent_Identity=25.25, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI69354671, Length=400, Percent_Identity=25.25, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI157502203, Length=201, Percent_Identity=29.3532338308458, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI157502201, Length=201, Percent_Identity=29.3532338308458, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI90421313, Length=184, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI2367384, Length=529, Percent_Identity=25.7088846880907, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1787041, Length=526, Percent_Identity=25.8555133079848, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789751, Length=505, Percent_Identity=25.9405940594059, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787182, Length=548, Percent_Identity=24.0875912408759, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1787164, Length=192, Percent_Identity=26.5625, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1789962, Length=197, Percent_Identity=26.3959390862944, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=198, Percent_Identity=25.7575757575758, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787029, Length=208, Percent_Identity=23.5576923076923, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=519, Percent_Identity=22.1579961464355, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17555318, Length=384, Percent_Identity=25.5208333333333, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17553372, Length=508, Percent_Identity=23.8188976377953, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320874, Length=539, Percent_Identity=20.4081632653061, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321121, Length=385, Percent_Identity=24.1558441558442, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325030, Length=186, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641342, Length=529, Percent_Identity=26.0869565217391, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24642252, Length=538, Percent_Identity=23.7918215613383, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI18859989, Length=538, Percent_Identity=23.7918215613383, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24666836, Length=519, Percent_Identity=22.7360308285164, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574259, Length=205, Percent_Identity=25.3658536585366, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550390, Length=173, Percent_Identity=26.5895953757225, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 56467; Mature: 56336

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLSLLLGKYEYNGN
CCEEEEEEEEEEEECCHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHHHEEECCC
ISADVTFEYFPYEVQEQSNFTIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSK
CEEEEEEEECCCEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
GEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYLKKKKGFILISHDRSFLDNCV
CCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHH
DHILSINKTNIEIQKGNFSSWWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
HHHHCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCC
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
PLTFHDKKLVELTDVAIEYDDRIVCEGVSFTIEQGERIAIQGKNGSGKSSILKLIYGEDI
EEEECCCHHEEHHHEEEECCCEEEECCCEEEECCCCEEEEECCCCCCHHHHHHHEECCCC
PHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHCIDESLFKSILRKLDFSREQFEKNI
CCCCEEECCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EDFSGGQKKKVLIAKSLCERAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
HHHCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHH
FCENVATKTIKL
HHHHHHHHHCCC
>Mature Secondary Structure 
SLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLSLLLGKYEYNGN
CEEEEEEEEEEEECCHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHHHEEECCC
ISADVTFEYFPYEVQEQSNFTIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSK
CEEEEEEEECCCEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
GEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYLKKKKGFILISHDRSFLDNCV
CCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHH
DHILSINKTNIEIQKGNFSSWWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
HHHHCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCC
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
PLTFHDKKLVELTDVAIEYDDRIVCEGVSFTIEQGERIAIQGKNGSGKSSILKLIYGEDI
EEEECCCHHEEHHHEEEECCCEEEECCCEEEECCCCEEEEECCCCCCHHHHHHHEECCCC
PHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHCIDESLFKSILRKLDFSREQFEKNI
CCCCEEECCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EDFSGGQKKKVLIAKSLCERAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
HHHCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHH
FCENVATKTIKL
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]