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The map label for this gene is hypA [H]

Identifier: 148380172

GI number: 148380172

Start: 2378179

End: 2378520

Strand: Direct

Name: hypA [H]

Synonym: CBO2219

Alternate gene names: 148380172

Gene position: 2378179-2378520 (Clockwise)

Preceding gene: 148380169

Following gene: 148380173

Centisome position: 61.18

GC content: 30.41

Gene sequence:

>342_bases
ATGCATGAAACAGCTGTGATTTGTGAAGTTGTAGATATTGTTTTAAAGACAGCAAAAGATAACTTTCTAGAAAAAATTAC
AAAAGTTATACTGCATATAGGAGAGTTTTCCTGTATTCAAGAAGACCAACTCAAATTTAGTTATAGAATAATTTCTAAGG
ATACTCTACTTGAAAGTTCAGATTTAATTATTGAATGGGTAAAACCACTGGCCTACTGTAGCCATTGTAATGAAACTTTT
CCAGTATCCTTTACTCATAAAGAATGTCCAATTTGTCATAAAGTCAGTGAAAAAATTGTATCTGGGTATGATACCTATGT
ATACAGTATAGAAGGTGATTAA

Upstream 100 bases:

>100_bases
GATGGAGTGATTCATGAAGATCACAAAGTATTTATGCCTGCCCTATCTAAAAATAGAGTACAGGTTAAGAAAAATATGAA
ATTTAAGGTGGCAAAATAAT

Downstream 100 bases:

>100_bases
AAATGAAAACCATAGAAATAAATGAAAGTGTTTATAAGAAAAATAGATCCATTGCCCACCATTTAAAAGATAAACTTCAT
GAAAAAAACATAAAAATGAT

Product: hydrogenase nickel incorporation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHETAVICEVVDIVLKTAKDNFLEKITKVILHIGEFSCIQEDQLKFSYRIISKDTLLESSDLIIEWVKPLAYCSHCNETF
PVSFTHKECPICHKVSEKIVSGYDTYVYSIEGD

Sequences:

>Translated_113_residues
MHETAVICEVVDIVLKTAKDNFLEKITKVILHIGEFSCIQEDQLKFSYRIISKDTLLESSDLIIEWVKPLAYCSHCNETF
PVSFTHKECPICHKVSEKIVSGYDTYVYSIEGD
>Mature_113_residues
MHETAVICEVVDIVLKTAKDNFLEKITKVILHIGEFSCIQEDQLKFSYRIISKDTLLESSDLIIEWVKPLAYCSHCNETF
PVSFTHKECPICHKVSEKIVSGYDTYVYSIEGD

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=111, Percent_Identity=29.7297297297297, Blast_Score=68, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 12962; Mature: 12962

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHETAVICEVVDIVLKTAKDNFLEKITKVILHIGEFSCIQEDQLKFSYRIISKDTLLESS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEEEEECCHHHCCCC
DLIIEWVKPLAYCSHCNETFPVSFTHKECPICHKVSEKIVSGYDTYVYSIEGD
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MHETAVICEVVDIVLKTAKDNFLEKITKVILHIGEFSCIQEDQLKFSYRIISKDTLLESS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEEEEECCHHHCCCC
DLIIEWVKPLAYCSHCNETFPVSFTHKECPICHKVSEKIVSGYDTYVYSIEGD
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA