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The map label for this gene is hypA

Identifier: 148360071

GI number: 148360071

Start: 2967685

End: 2968026

Strand: Reverse

Name: hypA

Synonym: LPC_2002

Alternate gene names: 148360071

Gene position: 2968026-2967685 (Counterclockwise)

Preceding gene: 148360070

Following gene: 148360072

Centisome position: 82.99

GC content: 37.13

Gene sequence:

>342_bases
ATGCATGAATTATGGTTATGTAAGCGTATTGTCGAGATTATCAAGCAACAAGCCACTGGCAATAAATGCCGAATGGTAAA
GAAAATAGTGCTGGAAATAGGGCAGCTAGTAGCAGTCGATAAGCACGCATTGAATTTTAGCTTTAAAGTGATAACTCAAG
GGACGATTGCACAAAATGCAGAATTATCAATTGTAGAAATCCCAGGTGAAGCAATATGCAATTCTTGTCAACAAATTGTA
CCAATGAAACAGTATTATGATGAATGCCTGGTTTGCGGCAATCATTCCTTAACGCTGACAAAAGGTGAAGAATTAAAAGT
GAAATCAATGGTGGTGGAATAA

Upstream 100 bases:

>100_bases
TCTCATTACTTTTCTCAAGATTAGTAGGATTTGGCATTGCTTTTTTTAGCATAGGTATTGCTATAATCAATTGCTGCAAA
TTGCTTTAAACAGGCTAAAA

Downstream 100 bases:

>100_bases
TGTGCGGGATATGCGGATGTTCAGTAGAAAAAGGTCAAACCATGGATAATGAGCACCATGCTACTCACCATGAGCATTCT
GTGCCTCATGAACATTCAAT

Product: hydrogenase nickel incorporation protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHELWLCKRIVEIIKQQATGNKCRMVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIV
PMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE

Sequences:

>Translated_113_residues
MHELWLCKRIVEIIKQQATGNKCRMVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIV
PMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE
>Mature_113_residues
MHELWLCKRIVEIIKQQATGNKCRMVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIV
PMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=41.5929203539823, Blast_Score=92, Evalue=1e-20,
Organism=Escherichia coli, GI1789081, Length=114, Percent_Identity=29.8245614035088, Blast_Score=66, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_LEGPA (Q5X252)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_124846.1
- STRING:   Q5X252
- GeneID:   3116847
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp2541
- LegioList:   lpp2541
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   MHEMSLC
- ProtClustDB:   CLSK833427
- BioCyc:   LPNE297246:LPP2541-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12689; Mature: 12689

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.8 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELWLCKRIVEIIKQQATGNKCRMVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNA
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCC
ELSIVEIPGEAICNSCQQIVPMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE
CEEEEECCHHHHHHHHHHHCCHHHHHHHHHEECCCEEEEECCCCEEHHEEECC
>Mature Secondary Structure
MHELWLCKRIVEIIKQQATGNKCRMVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNA
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCC
ELSIVEIPGEAICNSCQQIVPMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE
CEEEEECCHHHHHHHHHHHCCHHHHHHHHHEECCCEEEEECCCCEEHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA