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The map label for this gene is nixA [H]

Identifier: 148360070

GI number: 148360070

Start: 2968038

End: 2968715

Strand: Reverse

Name: nixA [H]

Synonym: LPC_2001

Alternate gene names: 148360070

Gene position: 2968715-2968038 (Counterclockwise)

Preceding gene: 148360067

Following gene: 148360071

Centisome position: 83.01

GC content: 37.32

Gene sequence:

>678_bases
ATGAATGATTCAGGTTGGTTTTTGATTTCAACTGCTCTTTTGCTTGGCATGCGTCATGGTTTTGATTTGGATCATCTGGC
AACGATCGATGCGATTAGTCGCACGGTTCGTTATAAACCTTCTTTATCGCGCATGGTTGGCTTTTTGTTTTCACTAGGCC
ATGGTTTGGTAGTTATTATTGTGAGTTTGATCATTGGCGGAGGTATTATTTCAGCGAGTACTCCTGAATGGTTAAATGAA
GTGGGAAATATTGTATCAGTTACCTGTTTATTGTTATTTGGGTTTTTAACTTTGTGGAATACGGTTCATTATTCATCTTC
TGCCATCATACCAACCAACTTAAGGAGTTATTTATTCAGGAAGCTTGCTGATAACAATGTACATCCTCTTATGATTCTTC
TCATTGGCGCGCTGTTTGCCTTATCTTTTGATACGATTAGTCAAATTGTATTGTTTTCACTTGCAGCCAGTGCTTTATCA
GGGTTTCTATTTTCCGGGTTATTAGGTTTTGTTTTTATGCTGGGAATGATGATGTCGGATGGATTAAATGGATTTTTTGT
AGCAAGCTTGATTCGGCGTGCTGATGGGATCTCATTACTTTTCTCAAGATTAGTAGGATTTGGCATTGCTTTTTTTAGCA
TAGGTATTGCTATAATCAATTGCTGCAAATTGCTTTAA

Upstream 100 bases:

>100_bases
AACCTACTCTTGGAAGTTGAGTCCATTGAGGGTTATAAATACAGTGAAAGTATTGATATATTGTCCACAGTCTTTAACAT
TAATAATGGCCTTATACTAA

Downstream 100 bases:

>100_bases
ACAGGCTAAAAATGCATGAATTATGGTTATGTAAGCGTATTGTCGAGATTATCAAGCAACAAGCCACTGGCAATAAATGC
CGAATGGTAAAGAAAATAGT

Product: high affinity nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MNDSGWFLISTALLLGMRHGFDLDHLATIDAISRTVRYKPSLSRMVGFLFSLGHGLVVIIVSLIIGGGIISASTPEWLNE
VGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPLMILLIGALFALSFDTISQIVLFSLAASALS
GFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGISLLFSRLVGFGIAFFSIGIAIINCCKLL

Sequences:

>Translated_225_residues
MNDSGWFLISTALLLGMRHGFDLDHLATIDAISRTVRYKPSLSRMVGFLFSLGHGLVVIIVSLIIGGGIISASTPEWLNE
VGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPLMILLIGALFALSFDTISQIVLFSLAASALS
GFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGISLLFSRLVGFGIAFFSIGIAIINCCKLL
>Mature_225_residues
MNDSGWFLISTALLLGMRHGFDLDHLATIDAISRTVRYKPSLSRMVGFLFSLGHGLVVIIVSLIIGGGIISASTPEWLNE
VGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPLMILLIGALFALSFDTISQIVLFSLAASALS
GFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGISLLFSRLVGFGIAFFSIGIAIINCCKLL

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 24379; Mature: 24379

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSGWFLISTALLLGMRHGFDLDHLATIDAISRTVRYKPSLSRMVGFLFSLGHGLVVII
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VSLIIGGGIISASTPEWLNEVGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
KLADNNVHPLMILLIGALFALSFDTISQIVLFSLAASALSGFLFSGLLGFVFMLGMMMSD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLNGFFVASLIRRADGISLLFSRLVGFGIAFFSIGIAIINCCKLL
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNDSGWFLISTALLLGMRHGFDLDHLATIDAISRTVRYKPSLSRMVGFLFSLGHGLVVII
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VSLIIGGGIISASTPEWLNEVGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
KLADNNVHPLMILLIGALFALSFDTISQIVLFSLAASALSGFLFSGLLGFVFMLGMMMSD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLNGFFVASLIRRADGISLLFSRLVGFGIAFFSIGIAIINCCKLL
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]