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The map label for this gene is panC [H]

Identifier: 148358603

GI number: 148358603

Start: 3186101

End: 3186859

Strand: Direct

Name: panC [H]

Synonym: LPC_0477

Alternate gene names: 148358603

Gene position: 3186101-3186859 (Clockwise)

Preceding gene: 148358604

Following gene: 148358602

Centisome position: 89.09

GC content: 39.92

Gene sequence:

>759_bases
ATGCAAATTTTTCATAATTTAAATGAGTGGATTCGCTTTAGAAATACCCTGTCCCCTGATTTATCCCTGGGGTTTGCTCC
AACTATGGGTAACTTGCATGCTGGACATGCTTCTTTGTTTTTAGCCAGTAGCAAAGAAAATCACTATACCGTCTCCAGTT
TGTTTGTTAACCCGACCCAATTTAATAACCCCGATGATTACAAGCATTATCCACGCACAGTCGATGCTGATCTCGAATTA
ATGACTCAGAATGGAGTTGATTTTTGTATACTCCCCAATGAAAATGAAATCTATACCGATGGCTATGCTTATCAAGTCCA
AGAAAACCGGCTTGGGCAATTGATGGAGGGAAAACACCGACCGGGGCATTTTAACGGAGTCCTGACCATCGTCATGAAAC
TCTTTAATTTGGTCAAACCGACCCGTGCTTATTTTGGTGAAAAAGATTACCAACAACTGTTGCTAATTCAAGGAATGGTA
AAAGCATTGTTCATGGATATTGAAATCAAATCTTGCCCCACAGTAAGAGAAAAAAGTGGCCTGGCCTGCAGCTCACGCAA
TAACAGGCTTACTCCAAGCCAAAGAGAAATCGCTGATGAATTTGCAAAAATATTTCATCAAAACAAATCCTCTGCCATGA
TAAGCAAAGAATTGGAAGCGCTTGGAATTACTGTAGAATATATTGAAGAATTCCAGGGCAGACGATTTGCCGCAGTAAAA
ATTGGCGATATCCGTCTCATTGATAATTATTTGCTATGA

Upstream 100 bases:

>100_bases
GAGCCAAAGACCATTTTATTGAAGCCTTAAACAGCTATGTCCAGCAAGTACAACAAATGCATTTCCCAGCTAATGAACAT
TCTTTCTAGGAAAATTATCC

Downstream 100 bases:

>100_bases
TTCAAACCAATTGGTGCGTGATAACAGGTGGACCTTCCTCAGGGAAAACCACTTTAATTAATCATTTGGCAGAGTTGGGA
TACAAAACTGCGCCAGAAAT

Product: pantoate-beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MQIFHNLNEWIRFRNTLSPDLSLGFAPTMGNLHAGHASLFLASSKENHYTVSSLFVNPTQFNNPDDYKHYPRTVDADLEL
MTQNGVDFCILPNENEIYTDGYAYQVQENRLGQLMEGKHRPGHFNGVLTIVMKLFNLVKPTRAYFGEKDYQQLLLIQGMV
KALFMDIEIKSCPTVREKSGLACSSRNNRLTPSQREIADEFAKIFHQNKSSAMISKELEALGITVEYIEEFQGRRFAAVK
IGDIRLIDNYLL

Sequences:

>Translated_252_residues
MQIFHNLNEWIRFRNTLSPDLSLGFAPTMGNLHAGHASLFLASSKENHYTVSSLFVNPTQFNNPDDYKHYPRTVDADLEL
MTQNGVDFCILPNENEIYTDGYAYQVQENRLGQLMEGKHRPGHFNGVLTIVMKLFNLVKPTRAYFGEKDYQQLLLIQGMV
KALFMDIEIKSCPTVREKSGLACSSRNNRLTPSQREIADEFAKIFHQNKSSAMISKELEALGITVEYIEEFQGRRFAAVK
IGDIRLIDNYLL
>Mature_252_residues
MQIFHNLNEWIRFRNTLSPDLSLGFAPTMGNLHAGHASLFLASSKENHYTVSSLFVNPTQFNNPDDYKHYPRTVDADLEL
MTQNGVDFCILPNENEIYTDGYAYQVQENRLGQLMEGKHRPGHFNGVLTIVMKLFNLVKPTRAYFGEKDYQQLLLIQGMV
KALFMDIEIKSCPTVREKSGLACSSRNNRLTPSQREIADEFAKIFHQNKSSAMISKELEALGITVEYIEEFQGRRFAAVK
IGDIRLIDNYLL

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=257, Percent_Identity=39.6887159533074, Blast_Score=171, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6322046, Length=215, Percent_Identity=41.3953488372093, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 28832; Mature: 28832

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIFHNLNEWIRFRNTLSPDLSLGFAPTMGNLHAGHASLFLASSKENHYTVSSLFVNPTQ
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCC
FNNPDDYKHYPRTVDADLELMTQNGVDFCILPNENEIYTDGYAYQVQENRLGQLMEGKHR
CCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCEEECCEEEEECHHHHHHHHCCCCC
PGHFNGVLTIVMKLFNLVKPTRAYFGEKDYQQLLLIQGMVKALFMDIEIKSCPTVREKSG
CCCHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCC
LACSSRNNRLTPSQREIADEFAKIFHQNKSSAMISKELEALGITVEYIEEFQGRRFAAVK
CEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEEE
IGDIRLIDNYLL
ECCEEEECCCCC
>Mature Secondary Structure
MQIFHNLNEWIRFRNTLSPDLSLGFAPTMGNLHAGHASLFLASSKENHYTVSSLFVNPTQ
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCC
FNNPDDYKHYPRTVDADLELMTQNGVDFCILPNENEIYTDGYAYQVQENRLGQLMEGKHR
CCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCEEECCEEEEECHHHHHHHHCCCCC
PGHFNGVLTIVMKLFNLVKPTRAYFGEKDYQQLLLIQGMVKALFMDIEIKSCPTVREKSG
CCCHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCC
LACSSRNNRLTPSQREIADEFAKIFHQNKSSAMISKELEALGITVEYIEEFQGRRFAAVK
CEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEEE
IGDIRLIDNYLL
ECCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA