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The map label for this gene is murG

Identifier: 148284829

GI number: 148284829

Start: 1494373

End: 1495452

Strand: Direct

Name: murG

Synonym: OTBS_1530

Alternate gene names: 148284829

Gene position: 1494373-1495452 (Clockwise)

Preceding gene: 148284828

Following gene: 148284833

Centisome position: 70.26

GC content: 31.3

Gene sequence:

>1080_bases
ATGAAAACAATATTTTTAGTTGGAGGTGGAACAGGTGGGCACTTATTTCCAGCGATTGCATTAGGAGAAGAACTACAGGA
GCGTGGTTATAATGTATACTTGATTACAGACACTAGGTGCGAAAAATATCTCCTAAATTTTAATTATAGTTTTAAAATCC
ATATTATGAATATGGTATCCATCTCTAATACAGGGATTAAAAAACTTTATGCCTATATAAGAATATTAGCTGCTTGTATA
ACTGGATTCAAATTAGTCTACTCAAATTCTCCAAGCCTCATAGTAGCTTTTGGAGGATATACTATTGCTCCTATTATTAT
AAATGGAATATTATTTAGAATTCCATTTATTCTACATGAGCAAAACAGTGTTTTAGGCCTAGCTAATAGGCTTTTTTTAA
GATATGCTAAAGCTATAACTGTAACGTTTGCTAATACTCTCAATTTGAATAATCGCTATAAACATAAAGTAATAGTTACA
GGAACTCCTGTGCGAAAAGCCTTAAGATTTACTCCAAAACGTAATTTTAACTCTAAAAATTTTCAGCTGTTAGTAATTGG
AGGTAGTCAAGGAACCAAAATCTTTTCTACTCTTGTGCCTAATGCAATCAAATTACTAGTCAATTGTGATCATGACTTTA
AAATTACTATTGTTCATCAGGCTGTAGCAAAGGATATTAATTACGTTAAAGCAATGTATACTGAACTAAATATAGAGCAT
GAAGTGAGTGATTTTTTTTACAATATTGCTGACAAGTACAAAAATTCTCATTTAGCAATTTGCAGAGCTGGAGCATCTAC
TATATCTGAAATAATATCTTTATGTCAACCTGCAATATTAGTACCATATCCTGTCTCTGCACAAAATCATCAGCTTTTTA
ATGCAAAAGCTATTGCAGATAATAAAGCTGGTTGGTGTATAGAGCAAAGCACTATCACACCTCATATTTTATTTGAAAAA
ATATTCACATTAATGCAATCACCAACATTATTAGCTTCTACTGAGTTGAAACTGAGAGAGATGAAAATTAATGCCGAAAA
CCTACTAGCTAATGTGGTAGATAAATTTATAGTAACTTAG

Upstream 100 bases:

>100_bases
TGGATCTTCCAGCGTCGCAGTAGCGATAGGAGTTGGAATATTACTTGCTCTTACAAGGCATAAAACTGATCTTAGTAAAT
ATAAACTCAAGATATAAAAT

Downstream 100 bases:

>100_bases
GTAAAATTAGATATAACTAAACCACTATAAAACAGTTATATTATATACTTTTTGAAAGGTATATCTGAGTTGTAGTGATA
GCCAAACTGTTATAACTGTT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNFNYSFKIHIMNMVSISNTGIKKLYAYIRILAACI
TGFKLVYSNSPSLIVAFGGYTIAPIIINGILFRIPFILHEQNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVT
GTPVRKALRFTPKRNFNSKNFQLLVIGGSQGTKIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEH
EVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPVSAQNHQLFNAKAIADNKAGWCIEQSTITPHILFEK
IFTLMQSPTLLASTELKLREMKINAENLLANVVDKFIVT

Sequences:

>Translated_359_residues
MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNFNYSFKIHIMNMVSISNTGIKKLYAYIRILAACI
TGFKLVYSNSPSLIVAFGGYTIAPIIINGILFRIPFILHEQNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVT
GTPVRKALRFTPKRNFNSKNFQLLVIGGSQGTKIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEH
EVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPVSAQNHQLFNAKAIADNKAGWCIEQSTITPHILFEK
IFTLMQSPTLLASTELKLREMKINAENLLANVVDKFIVT
>Mature_359_residues
MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNFNYSFKIHIMNMVSISNTGIKKLYAYIRILAACI
TGFKLVYSNSPSLIVAFGGYTIAPIIINGILFRIPFILHEQNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVT
GTPVRKALRFTPKRNFNSKNFQLLVIGGSQGTKIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEH
EVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPVSAQNHQLFNAKAIADNKAGWCIEQSTITPHILFEK
IFTLMQSPTLLASTELKLREMKINAENLLANVVDKFIVT

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=320, Percent_Identity=29.375, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_ORITB (A5CEL6)

Other databases:

- EMBL:   AM494475
- RefSeq:   YP_001248919.1
- ProteinModelPortal:   A5CEL6
- SMR:   A5CEL6
- STRING:   A5CEL6
- GeneID:   5217909
- GenomeReviews:   AM494475_GR
- KEGG:   ots:OTBS_1530
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   OTSU357244:OTBS_1530-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40203; Mature: 40203

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNFNYSFKIHIMNMVS
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCEEEEEEEEEEEE
ISNTGIKKLYAYIRILAACITGFKLVYSNSPSLIVAFGGYTIAPIIINGILFRIPFILHE
ECCCCHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCEEEHHHHHHHHHHHCCEEEEC
QNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVTGTPVRKALRFTPKRNFNSKN
CCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEEEEECCCHHHHHHCCCCCCCCCCC
FQLLVIGGSQGTKIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEH
EEEEEEECCCCCHHHHHHCCHHEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCH
EVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPVSAQNHQLFNAKAIAD
HHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEEEECC
NKAGWCIEQSTITPHILFEKIFTLMQSPTLLASTELKLREMKINAENLLANVVDKFIVT
CCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEECCEEEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNFNYSFKIHIMNMVS
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCEEEEEEEEEEEE
ISNTGIKKLYAYIRILAACITGFKLVYSNSPSLIVAFGGYTIAPIIINGILFRIPFILHE
ECCCCHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCEEEHHHHHHHHHHHCCEEEEC
QNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVTGTPVRKALRFTPKRNFNSKN
CCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEEEEECCCHHHHHHCCCCCCCCCCC
FQLLVIGGSQGTKIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEH
EEEEEEECCCCCHHHHHHCCHHEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCH
EVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPVSAQNHQLFNAKAIAD
HHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEEEECC
NKAGWCIEQSTITPHILFEKIFTLMQSPTLLASTELKLREMKINAENLLANVVDKFIVT
CCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEECCEEEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA