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The map label for this gene is ftsW [H]

Identifier: 148284828

GI number: 148284828

Start: 1493242

End: 1494369

Strand: Direct

Name: ftsW [H]

Synonym: OTBS_1529

Alternate gene names: 148284828

Gene position: 1493242-1494369 (Clockwise)

Preceding gene: 148284827

Following gene: 148284829

Centisome position: 70.2

GC content: 32.0

Gene sequence:

>1128_bases
ATGAACTATAATTCGACTGAAAAGTTTAGAATATTATGGCGCTGGTGGAAAAGTATAGATCAATACACGGTATTTTTATT
ATGTATTTTATCTGCTTTAAGCCTAATGCTAGTAACAACCTCTGGCGCTGCAGTAGCAAATAGAATAGGAGTTCCACAGT
CGTATTTTGCTAGCAAGCATATATTTTATGTTGTACTAGCAGTAGGTACAACATTTGTTGTATCGTTTCTCAATAAAACT
ACAATAAAGCGTTTAGCTATTTTAGGATTTATTCTAAATATTATATTATTAATATTTATTAAATTTTATGGTAATCCTAT
TAAGGGAGCTAAAAGGTGGATTAATATTGGAGGAATATCATTGCAACCTTCTGAATTTGTAAAACCATTTTTTTTAGTGA
TTACTGGATGGCTTCTTTCAGCTATTCAAAGCAATGAAATTCGCTTTATTGTTACTATTATCTTATATTTAATAGTAGCA
TTACTGCTAATTACTCAGCCTGATTTTGGTATGTTAATAACAATTTCGGTTGCATTTGGAATACAATTATTTATAGCAGG
TATACCGTTACTATGGCTCTTGATTTTGATATGTATATCAATTGCTGGAACAGCAGGAGCATATTCATTATTACCGCATG
TTAAGAGAAGAATTAATAGTTTTTTGGATCCAGCCAATAGCGAAAATTACCAAGTCATGAAGTCTTTACAAGCATTTAAA
AATGGAGGACTATATGGCAAAGGGCCAGGAGAAGGTTTAGTCAAGCACATGTTACCTGATTCTCATACTGACTTTATTTT
TGCTGTTGCTGGTGAAGAGTTAGGAGCTATAGTCTGTTTAATAATTGTAGCAATTTTTACTTTTATTGTTATATATGGAT
TCATCAAATTGCTCTTTGAAGAGGATAATTATACAATTTTTGTATCTTCAGGCATACTTTCACAGTTTGGATTTCAGGCT
ATAGTTAATATGTGTGTTAGTACTAACCTGCTTCCAACTAAAGGTATGACTTTGCCATTTATTAGTTACGGTGGATCTTC
CAGCGTCGCAGTAGCGATAGGAGTTGGAATATTACTTGCTCTTACAAGGCATAAAACTGATCTTAGTAAATATAAACTCA
AGATATAA

Upstream 100 bases:

>100_bases
TGCTCCTGCTTGCGCTTCATTTGATCAGTTTAAGAACTTTGAAGATAGGGGTAATCAATTTATAAAAATATCTCAAAAAT
TTATAACAGAATAAAAATAT

Downstream 100 bases:

>100_bases
AATATGAAAACAATATTTTTAGTTGGAGGTGGAACAGGTGGGCACTTATTTCCAGCGATTGCATTAGGAGAAGAACTACA
GGAGCGTGGTTATAATGTAT

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNYNSTEKFRILWRWWKSIDQYTVFLLCILSALSLMLVTTSGAAVANRIGVPQSYFASKHIFYVVLAVGTTFVVSFLNKT
TIKRLAILGFILNIILLIFIKFYGNPIKGAKRWINIGGISLQPSEFVKPFFLVITGWLLSAIQSNEIRFIVTIILYLIVA
LLLITQPDFGMLITISVAFGIQLFIAGIPLLWLLILICISIAGTAGAYSLLPHVKRRINSFLDPANSENYQVMKSLQAFK
NGGLYGKGPGEGLVKHMLPDSHTDFIFAVAGEELGAIVCLIIVAIFTFIVIYGFIKLLFEEDNYTIFVSSGILSQFGFQA
IVNMCVSTNLLPTKGMTLPFISYGGSSSVAVAIGVGILLALTRHKTDLSKYKLKI

Sequences:

>Translated_375_residues
MNYNSTEKFRILWRWWKSIDQYTVFLLCILSALSLMLVTTSGAAVANRIGVPQSYFASKHIFYVVLAVGTTFVVSFLNKT
TIKRLAILGFILNIILLIFIKFYGNPIKGAKRWINIGGISLQPSEFVKPFFLVITGWLLSAIQSNEIRFIVTIILYLIVA
LLLITQPDFGMLITISVAFGIQLFIAGIPLLWLLILICISIAGTAGAYSLLPHVKRRINSFLDPANSENYQVMKSLQAFK
NGGLYGKGPGEGLVKHMLPDSHTDFIFAVAGEELGAIVCLIIVAIFTFIVIYGFIKLLFEEDNYTIFVSSGILSQFGFQA
IVNMCVSTNLLPTKGMTLPFISYGGSSSVAVAIGVGILLALTRHKTDLSKYKLKI
>Mature_375_residues
MNYNSTEKFRILWRWWKSIDQYTVFLLCILSALSLMLVTTSGAAVANRIGVPQSYFASKHIFYVVLAVGTTFVVSFLNKT
TIKRLAILGFILNIILLIFIKFYGNPIKGAKRWINIGGISLQPSEFVKPFFLVITGWLLSAIQSNEIRFIVTIILYLIVA
LLLITQPDFGMLITISVAFGIQLFIAGIPLLWLLILICISIAGTAGAYSLLPHVKRRINSFLDPANSENYQVMKSLQAFK
NGGLYGKGPGEGLVKHMLPDSHTDFIFAVAGEELGAIVCLIIVAIFTFIVIYGFIKLLFEEDNYTIFVSSGILSQFGFQA
IVNMCVSTNLLPTKGMTLPFISYGGSSSVAVAIGVGILLALTRHKTDLSKYKLKI

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=366, Percent_Identity=31.6939890710383, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786853, Length=292, Percent_Identity=29.1095890410959, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41419; Mature: 41419

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYNSTEKFRILWRWWKSIDQYTVFLLCILSALSLMLVTTSGAAVANRIGVPQSYFASKH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
IFYVVLAVGTTFVVSFLNKTTIKRLAILGFILNIILLIFIKFYGNPIKGAKRWINIGGIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCC
LQPSEFVKPFFLVITGWLLSAIQSNEIRFIVTIILYLIVALLLITQPDFGMLITISVAFG
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHH
IQLFIAGIPLLWLLILICISIAGTAGAYSLLPHVKRRINSFLDPANSENYQVMKSLQAFK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
NGGLYGKGPGEGLVKHMLPDSHTDFIFAVAGEELGAIVCLIIVAIFTFIVIYGFIKLLFE
CCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDNYTIFVSSGILSQFGFQAIVNMCVSTNLLPTKGMTLPFISYGGSSSVAVAIGVGILLA
CCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
LTRHKTDLSKYKLKI
HHHCCCCHHHHEECC
>Mature Secondary Structure
MNYNSTEKFRILWRWWKSIDQYTVFLLCILSALSLMLVTTSGAAVANRIGVPQSYFASKH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
IFYVVLAVGTTFVVSFLNKTTIKRLAILGFILNIILLIFIKFYGNPIKGAKRWINIGGIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCC
LQPSEFVKPFFLVITGWLLSAIQSNEIRFIVTIILYLIVALLLITQPDFGMLITISVAFG
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHH
IQLFIAGIPLLWLLILICISIAGTAGAYSLLPHVKRRINSFLDPANSENYQVMKSLQAFK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
NGGLYGKGPGEGLVKHMLPDSHTDFIFAVAGEELGAIVCLIIVAIFTFIVIYGFIKLLFE
CCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDNYTIFVSSGILSQFGFQAIVNMCVSTNLLPTKGMTLPFISYGGSSSVAVAIGVGILLA
CCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
LTRHKTDLSKYKLKI
HHHCCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]