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The map label for this gene is ygfA

Identifier: 148284833

GI number: 148284833

Start: 1502477

End: 1503049

Strand: Direct

Name: ygfA

Synonym: OTBS_1540

Alternate gene names: NA

Gene position: 1502477-1503049 (Clockwise)

Preceding gene: 148284829

Following gene: 148284834

Centisome position: 70.64

GC content: 28.97

Gene sequence:

>573_bases
ATGCATCAAAATTATTATAAACAAACTCTACGTTCCAAATATAAGAATATACGAATCTTGGCAAATAAACAATTAAAAAG
TTGTTGTCAACAAAGCCATCAAATCTTGTTACAAGCTGTATATATTCTTACTTCATTACTTCCTACTAATTCTGTAATTG
GTATTTATTATCCATTTAAAGGCGAAGTTAATGTATTAGATTTGTTAATGATGATGCCTAACTATAAATTTGCTCTACCA
GCTCTTATTAACAAAAAAATGTTATATAGATACTATTATATAGGCTGCCCAATCAAAAAACAAGAACACGAAATATATAC
TCCAGTTGGTACTGATATAGTGATACCATCTGCATTATTAGTTCCTGGTTTGGTGTTTGATGTTGCTGGTTATAGAATTG
GCTTTGGTAAAGGATATTATGATCAATACATATCGCAAGTCAGAAGTATTAATAGCAATAACATAGCAATTGGAGTATGT
TTTGATGTACAGCTAAGAAACTTTGTACCTAGGGAGTTGCATGATCAAAAAATGGACTATATTATAACAAATAAAATATT
AATTGTAACATGA

Upstream 100 bases:

>100_bases
TGCAATAAACTATTATACATTATACTTAAAATAATTCTAAATTAAGCAATTACTGTGTTTAATAATGTTTTATTACTCAA
TCTGTTAATATAACCTCAGT

Downstream 100 bases:

>100_bases
ATATAATAGATATAATTTCTCTTGTAATCTTTATTAGCGCAATTACCTTAGGGTTTTATAAAGGTGGTTTAAAATTGATT
ATTGGGTCAATTTTTTTTGT

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: 5-Formyltetrahydrofolate Cyclo-Ligase Family Protein; 5 10-Methenyltetrahydrofolate Synthetase; 5-Formyltetrahydrofolate Cyclo-Ligase Protein; Porphobilinogen Deaminase; 5-Formyltetrahydrofolate Cyclo- Ligase; 10-Methenyltetrahydrofolate Synthetase.

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MHQNYYKQTLRSKYKNIRILANKQLKSCCQQSHQILLQAVYILTSLLPTNSVIGIYYPFKGEVNVLDLLMMMPNYKFALP
ALINKKMLYRYYYIGCPIKKQEHEIYTPVGTDIVIPSALLVPGLVFDVAGYRIGFGKGYYDQYISQVRSINSNNIAIGVC
FDVQLRNFVPRELHDQKMDYIITNKILIVT

Sequences:

>Translated_190_residues
MHQNYYKQTLRSKYKNIRILANKQLKSCCQQSHQILLQAVYILTSLLPTNSVIGIYYPFKGEVNVLDLLMMMPNYKFALP
ALINKKMLYRYYYIGCPIKKQEHEIYTPVGTDIVIPSALLVPGLVFDVAGYRIGFGKGYYDQYISQVRSINSNNIAIGVC
FDVQLRNFVPRELHDQKMDYIITNKILIVT
>Mature_190_residues
MHQNYYKQTLRSKYKNIRILANKQLKSCCQQSHQILLQAVYILTSLLPTNSVIGIYYPFKGEVNVLDLLMMMPNYKFALP
ALINKKMLYRYYYIGCPIKKQEHEIYTPVGTDIVIPSALLVPGLVFDVAGYRIGFGKGYYDQYISQVRSINSNNIAIGVC
FDVQLRNFVPRELHDQKMDYIITNKILIVT

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.3.3.2

Molecular weight: Translated: 22001; Mature: 22001

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQNYYKQTLRSKYKNIRILANKQLKSCCQQSHQILLQAVYILTSLLPTNSVIGIYYPFK
CCCHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GEVNVLDLLMMMPNYKFALPALINKKMLYRYYYIGCPIKKQEHEIYTPVGTDIVIPSALL
CCHHHHHHHHHCCCCCEEHHHHHHHHHEEHEEEECCCCCCCCCEEECCCCCCEECCHHHH
VPGLVFDVAGYRIGFGKGYYDQYISQVRSINSNNIAIGVCFDVQLRNFVPRELHDQKMDY
HHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCEEEEEEEEEEHHHCCCHHHHHHHCCE
IITNKILIVT
EEECEEEEEC
>Mature Secondary Structure
MHQNYYKQTLRSKYKNIRILANKQLKSCCQQSHQILLQAVYILTSLLPTNSVIGIYYPFK
CCCHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GEVNVLDLLMMMPNYKFALPALINKKMLYRYYYIGCPIKKQEHEIYTPVGTDIVIPSALL
CCHHHHHHHHHCCCCCEEHHHHHHHHHEEHEEEECCCCCCCCCEEECCCCCCEECCHHHH
VPGLVFDVAGYRIGFGKGYYDQYISQVRSINSNNIAIGVCFDVQLRNFVPRELHDQKMDY
HHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCEEEEEEEEEEHHHCCCHHHHHHHCCE
IITNKILIVT
EEECEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA