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The map label for this gene is gppA [C]

Identifier: 148284273

GI number: 148284273

Start: 439896

End: 441359

Strand: Direct

Name: gppA [C]

Synonym: OTBS_0465

Alternate gene names: 148284273

Gene position: 439896-441359 (Clockwise)

Preceding gene: 148284267

Following gene: 148284274

Centisome position: 20.68

GC content: 28.01

Gene sequence:

>1464_bases
ATGTATTACGCTGTAATGGATATTGGTTCAAATGCTATTAGAGCTGCTATATATAAAAACTTAAATATTGCTAGTGCTAA
AATTTACAGTGATAAATTTAAAGCCGATATTTGGTCCTTACTAGAATGTGATGATATAGATATAACACATCAATCATATC
TTATTATAGAGCATTTTATACATATTTTTAACCGGATTGGAGTTAAAAATGTAAAATGCGTTGCTACTGCTGTACTTAGA
TGGCATCATAAAGCATTAATATTTAAAGATATTATTCAACAAAGATATGGAATTGATGTAGAAATCCTTTCAGGAGAACA
GGAAGCATATTTAACTACTATTGGTTTAATGCTTGGAATTCCTGATGTAGATGGAATTGTAGCTGACCTTGGAGGAGGTA
GCTTAGAATTGATTGAAGTACGACAGTCTAAAATTATTAGTTGTACTTCACTACAGTTAGGCACTAAACTGCTTAATAAT
TTGAAAACTATTAGCATTGATTTTATTAAAGAGCAAATTCAAAAATTTAGTAATGTTGGTTATCAAAATCTATATTTAAT
TGGAGGAGCGTTTCGAATTATTACTAGATTTTATATGATGTTTATTAACTATCCTCTTGTTAATACACACAACTTTAGAG
TTCAGGCTAATAATATTCTGTTATATATTGCTGAGTTAGACAATATAGAAAATATTAATTCAAGTTATCGCAGCAGCAAA
TTTAAAGTAAATGCTCATGCAACAATGATATTACAGGCTTTAATAGAGGTTTTTAATATCAAAACTGTTGTAGTTTCTAA
TTACGGGCTTAAGGAAGGTGTGCATGTACGAAACTGCTTTTTACCTAACAATGAACAATTACCTGCAGATGTTGAAAAGC
TAAACAATAGTTTTGTTAATTTTTTTCATACTGTTAAAAATGATAACATGTTATATAAATACTGTTCTAAATTAGTTAAT
TTGCAGGAAGATGATTGTTATTTAGAGCAATATGTTAAAATGATTTTACCATTATTAATACAACCTAATGAAGCAACTGA
ACAGATTATTAGAGCATCTATTATTCTTGTAAATTATACTCAAGAGATTAATACATTGTTTAGAACAAGCTTTTTATCAG
AATATATTTTAACATCAGATTTACCATTTAGTCATAGTCAAAGAGTAATATTATCTCTAGTTTTAGCTAAGGCTGTTTCT
GATTCAAAATCAGTATTGCGTATTACTAAAATAGCAAAACAAATTTTGCCAAAAACAGAATTTTATAATAGTATGATTAT
TGGTACTGTAATTAGCATTGCTAAAGATATTGATGGGTATCCTCTAAAAAGCCCGTCATTTTCACTACCAGTAAATTATA
AATTTATTGAGCTTAGTACTACTTCTGTATTACCAAAGATGATTTGGACTAAAGTTGTTAGAAAGTTAAAAAAAATATGT
TCCCTTAGATCATATCGGCAATAA

Upstream 100 bases:

>100_bases
TTCTCCTTTTCATATTCTCGTGTTATAAATGAAATTACTACCAATTATTATAATATTGTAATATATATATAATGCTAAGT
CATTTATATAATATATACAT

Downstream 100 bases:

>100_bases
TTTCTGCAAAAGATAAATAGCTGTAAGATATGCAAAAGGTAGTCAAAAAACCACCTGGTTATCATACTTTAATATGCTGA
AAAGATTTAAAGTAGCCAAA

Product: Ppx/GppA family phosphotase

Products: (polyphosphate)n-1; phosphate

Alternate protein names: Exopolyphosphatase; Phosphatase Ppx/GppA Family; Guanosine Pentaphosphate Phosphohydrolase; Ppx/GppA Family Phosphatase; Ppx/Gppa Phosphatase; Ppx/GppA Phosphatase Family; Phosphatase; Guanosine Pentaphosphate Phosphohydrolase Gppa; Guanosine-5-Triphosphate 3'-Diphosphate Pyrophosphatase; Ppx/GppA Phosphatase Family Protein; Bifunctional 3-Dehydroquinate Synthase/Phosphatase; Exopolyphosphatase Protein; Guanosine Pentaphosphate Phosphohydrolase GPPA; Nucleoside Diphosphate Kinase; Ppx/GppA Family Phosphotase; Exopolyphosphatase Homolog; Exopolyphosphatase Ppx; Guanosine Pentaphosphate Phosphohydrolase Phage Proteinpa; Fumarate Reductase

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MYYAVMDIGSNAIRAAIYKNLNIASAKIYSDKFKADIWSLLECDDIDITHQSYLIIEHFIHIFNRIGVKNVKCVATAVLR
WHHKALIFKDIIQQRYGIDVEILSGEQEAYLTTIGLMLGIPDVDGIVADLGGGSLELIEVRQSKIISCTSLQLGTKLLNN
LKTISIDFIKEQIQKFSNVGYQNLYLIGGAFRIITRFYMMFINYPLVNTHNFRVQANNILLYIAELDNIENINSSYRSSK
FKVNAHATMILQALIEVFNIKTVVVSNYGLKEGVHVRNCFLPNNEQLPADVEKLNNSFVNFFHTVKNDNMLYKYCSKLVN
LQEDDCYLEQYVKMILPLLIQPNEATEQIIRASIILVNYTQEINTLFRTSFLSEYILTSDLPFSHSQRVILSLVLAKAVS
DSKSVLRITKIAKQILPKTEFYNSMIIGTVISIAKDIDGYPLKSPSFSLPVNYKFIELSTTSVLPKMIWTKVVRKLKKIC
SLRSYRQ

Sequences:

>Translated_487_residues
MYYAVMDIGSNAIRAAIYKNLNIASAKIYSDKFKADIWSLLECDDIDITHQSYLIIEHFIHIFNRIGVKNVKCVATAVLR
WHHKALIFKDIIQQRYGIDVEILSGEQEAYLTTIGLMLGIPDVDGIVADLGGGSLELIEVRQSKIISCTSLQLGTKLLNN
LKTISIDFIKEQIQKFSNVGYQNLYLIGGAFRIITRFYMMFINYPLVNTHNFRVQANNILLYIAELDNIENINSSYRSSK
FKVNAHATMILQALIEVFNIKTVVVSNYGLKEGVHVRNCFLPNNEQLPADVEKLNNSFVNFFHTVKNDNMLYKYCSKLVN
LQEDDCYLEQYVKMILPLLIQPNEATEQIIRASIILVNYTQEINTLFRTSFLSEYILTSDLPFSHSQRVILSLVLAKAVS
DSKSVLRITKIAKQILPKTEFYNSMIIGTVISIAKDIDGYPLKSPSFSLPVNYKFIELSTTSVLPKMIWTKVVRKLKKIC
SLRSYRQ
>Mature_487_residues
MYYAVMDIGSNAIRAAIYKNLNIASAKIYSDKFKADIWSLLECDDIDITHQSYLIIEHFIHIFNRIGVKNVKCVATAVLR
WHHKALIFKDIIQQRYGIDVEILSGEQEAYLTTIGLMLGIPDVDGIVADLGGGSLELIEVRQSKIISCTSLQLGTKLLNN
LKTISIDFIKEQIQKFSNVGYQNLYLIGGAFRIITRFYMMFINYPLVNTHNFRVQANNILLYIAELDNIENINSSYRSSK
FKVNAHATMILQALIEVFNIKTVVVSNYGLKEGVHVRNCFLPNNEQLPADVEKLNNSFVNFFHTVKNDNMLYKYCSKLVN
LQEDDCYLEQYVKMILPLLIQPNEATEQIIRASIILVNYTQEINTLFRTSFLSEYILTSDLPFSHSQRVILSLVLAKAVS
DSKSVLRITKIAKQILPKTEFYNSMIIGTVISIAKDIDGYPLKSPSFSLPVNYKFIELSTTSVLPKMIWTKVVRKLKKIC
SLRSYRQ

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.11; 3.6.1.40

Molecular weight: Translated: 55626; Mature: 55626

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYAVMDIGSNAIRAAIYKNLNIASAKIYSDKFKADIWSLLECDDIDITHQSYLIIEHFI
CEEEEEECCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
HIFNRIGVKNVKCVATAVLRWHHKALIFKDIIQQRYGIDVEILSGEQEAYLTTIGLMLGI
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCC
PDVDGIVADLGGGSLELIEVRQSKIISCTSLQLGTKLLNNLKTISIDFIKEQIQKFSNVG
CCCCCHHEECCCCCEEEEEEHHHHHEEEHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCC
YQNLYLIGGAFRIITRFYMMFINYPLVNTHNFRVQANNILLYIAELDNIENINSSYRSSK
CCEEEEEHHHHHHHHHHHHHHHCCCEECCCEEEEEECCEEEEEEECCCCHHCCHHHCCCC
FKVNAHATMILQALIEVFNIKTVVVSNYGLKEGVHVRNCFLPNNEQLPADVEKLNNSFVN
EEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
FFHTVKNDNMLYKYCSKLVNLQEDDCYLEQYVKMILPLLIQPNEATEQIIRASIILVNYT
HHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECH
QEINTLFRTSFLSEYILTSDLPFSHSQRVILSLVLAKAVSDSKSVLRITKIAKQILPKTE
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
FYNSMIIGTVISIAKDIDGYPLKSPSFSLPVNYKFIELSTTSVLPKMIWTKVVRKLKKIC
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHH
SLRSYRQ
HHHHCCC
>Mature Secondary Structure
MYYAVMDIGSNAIRAAIYKNLNIASAKIYSDKFKADIWSLLECDDIDITHQSYLIIEHFI
CEEEEEECCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
HIFNRIGVKNVKCVATAVLRWHHKALIFKDIIQQRYGIDVEILSGEQEAYLTTIGLMLGI
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCC
PDVDGIVADLGGGSLELIEVRQSKIISCTSLQLGTKLLNNLKTISIDFIKEQIQKFSNVG
CCCCCHHEECCCCCEEEEEEHHHHHEEEHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCC
YQNLYLIGGAFRIITRFYMMFINYPLVNTHNFRVQANNILLYIAELDNIENINSSYRSSK
CCEEEEEHHHHHHHHHHHHHHHCCCEECCCEEEEEECCEEEEEEECCCCHHCCHHHCCCC
FKVNAHATMILQALIEVFNIKTVVVSNYGLKEGVHVRNCFLPNNEQLPADVEKLNNSFVN
EEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
FFHTVKNDNMLYKYCSKLVNLQEDDCYLEQYVKMILPLLIQPNEATEQIIRASIILVNYT
HHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECH
QEINTLFRTSFLSEYILTSDLPFSHSQRVILSLVLAKAVSDSKSVLRITKIAKQILPKTE
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
FYNSMIIGTVISIAKDIDGYPLKSPSFSLPVNYKFIELSTTSVLPKMIWTKVVRKLKKIC
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHH
SLRSYRQ
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (polyphosphate)n; H2O

Specific reaction: (polyphosphate)n + H2O = (polyphosphate)n-1 + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA