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The map label for this gene is cutL [H]

Identifier: 148261164

GI number: 148261164

Start: 2398168

End: 2400522

Strand: Reverse

Name: cutL [H]

Synonym: Acry_2174

Alternate gene names: 148261164

Gene position: 2400522-2398168 (Counterclockwise)

Preceding gene: 148261165

Following gene: 148261162

Centisome position: 70.83

GC content: 72.44

Gene sequence:

>2355_bases
ATGAACGGCGCCGACCGGCCGATCGGACGGGCGATGGCGCGGCCGGATGCGCGGCGGCTGACCCAGGGGCGCGGGCTGTT
CGCCAGCGATATCGCGCTGCCGCGCATGGTGCATGCGGCGTTCCTGCGATCGCCCTATGCGCATGCCGAGATCAGGGCGA
TCGACCTGGCGCCGGCGCGGGAGATGCCGGGGGTGGTCGGCGTGTTCGACGCGGCGGCGCTGGAGGGGCGGTGCGCGCCG
TGGGTCGGCGTGCTGACGCATCTCAAGGGATTGAAATCGGCGCCGCAATATCCGCTGGCGCGAGGACGGGTCCGGTTCCA
GGGCGAGCCGGTGGCGATGGTGGTGGCGGCGAGCCGGGCCGAGGCGGAGGATGCGGCGGAGCGGATTCTCGTGGAGTACG
CGCCGCTCGCGCCGGTGGTCGATCCGCTGGCGGCGCTCGCGCCGGGGGCGGCGGCGATCCATCCCGAACTCGGGGATAAT
CTCGCGTTCGCGCGGACGATCGAGGCGGGCGGCGGGGCGGCGGCGATCGACGCGGCGGCGGAGCGCGTGGCGCTGGAGTT
CGATTTCGCCCGGCATACCGGGGTGACGCTGGAGCCGCGCGCGCTGGTGGCGGACTGGAACGAGGGCGAGCAGCGGCTGA
CCGTGCATCTCGGCACCCAGGTGCCGCACATGTTCCAGACCGTGCTGGCCACATTGCTCGGCCTCGCCGAGCGGCAAATC
CGGGTGATCGGGCCGGATGTGGGCGGGTCGTTCGGGATCAAGATCCATGTCTATCCCGACGAGATGGCGGCGGTGGCGGC
GAGCCGCATCCTGCGCCGGCCGGTGCGGTTCGTGGCCGACCGGCTGGAGAGTTTCACCGGCGATATCCATGCGCGCGGGC
ACCGGGTGTCGGCGCGGATCGGGGTGGCGGAAGACGGGCGGATCGAGGGGTTCGCGGTGGACGATCTGACCGGGGTGGGG
CCGTATTCGGCCTATCCGCGCACCTCGGCGGTGGAGGCGAACCAGGTGATCAATCTGGTCGGCGGGCCGTATGATTTCGC
GCATTACGCGGCGCGGGCGCGGGTGGTGTTCCAGACCAAGGCGATGATGTCGCAATATCGCGCGGTGGGGCATCCGATCG
CGACCGCGGTGACGGAGGCGCTGGTGGACGAGGCGGCGCGGCGGCGGGGGATCGACCCGGTCGAGATGCGGCGGCGCAAC
CTGATCGCCGACGACGCCTATCCCTGCGCCTCGCCGGCGGGGATGAGGTTCGAGGCGCTGTCGCACCATGCCTGTCTCGA
CGAGCTGGTCCGGCTGATGGACTACGACGCGCTGCGGGCGGAGCAGGCCGGGCTGCGGGCGCGCGGGGTGTGGCGGGGCA
TCGGGATCGCGAGTTTCATCGAGATCACCAATCCGGGGGCGGCGTTCTACGGCGTCGGCGGGGCGCGGATCGCCGCGCAG
GACGGGGCGACGGCGCGGCTCGATGCGGCCGGCGACGTGGTGCTGCATGCCGGCGCCACCGAGCAGGGGCAGGGGACGAC
GACGATCCTCGCCCAGGTGACGGCCGCGGCGATGGGGGTGGACCCGGCGCGGGTGCTGGTGAAGCTCGGCGATACCGACG
CCACACCCTATGGCGGCGGCACCTGGGCCTCGCGCGGGGCGGGGGTGGGCGGCGAGGCGGCGTTTCGCGCCGCATCCGCG
CTGCGGGAGAATGTGCTGGCGCTGGCGGCGAGCATCCTGCAGGCCGCCCCGGAGGCGCTCGACATCAGGGATGGCGCGAT
CGTCGATGCGGCGGGCGGGGCCGAGCGGATGAGCCTCGCCGAGCTGGCGCGCATCGCCCATTTCCGGCCCGACACGTTGC
CGCAGGGGGTGGAGCCGGCGCTGGTCGCGAGCCGGCATTACGTGCCGCGGGAGTATCCCTTCGCCTTCACCAACGGGGTG
CAGGCGGCGGTGGTGGAGGTGGACGCCGAGACCGGCTTCGTGCGGCTGCTGAAGCATTTCGTGGTCGAGGATTGCGGGAC
GATCATCAACCCGCTGCTGGTGGACGAGCAGATTCGCGGCGGCGTGGTGCAGGGGCTGGGGGCGGCGCTGTTCGAGGAAT
GCCGCTACGATTCCGAGGGGCAGATGCTGAACGCGACGATGGCGGATTATCTGGTGCCGATGGCGGCCGAGATGCCGGAC
ATCGTGATCGGCCATGTCTGCACGCCGACGCGGGAAAGCCATATCGGCGCCAAGGGCGTGGGCGAGGCCGGCACGGCGGC
GGCGGCGGCGGCGGTGCTGAACGCGGTGAACGACGCGCTCGCACCGCGAGGCGCGCGGATCACGGCGCTGCCGATCACGC
CCGCGCGCGTGCTGGAAGCCCTCGGCATCGGCTGA

Upstream 100 bases:

>100_bases
CGGCGATCCGCGCGCATCTTTCGGGCAATTACTGCCGCTGCACCGGATATGAGGCGATCGTCGACGCGGTCGAGGCGACG
GCGCGGGCGCGGAGGGCGGC

Downstream 100 bases:

>100_bases
CGCGGAGGGCGCCGGCCGCGGTCAGCGGCCGGTCAGGATCTGACGCGGTCAGCGGCCGGTGAGGATCTGACGCGGTCAGC
GGCCGGTCAGGATCTGACGC

Product: molybdopterin binding aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 784; Mature: 784

Protein sequence:

>784_residues
MNGADRPIGRAMARPDARRLTQGRGLFASDIALPRMVHAAFLRSPYAHAEIRAIDLAPAREMPGVVGVFDAAALEGRCAP
WVGVLTHLKGLKSAPQYPLARGRVRFQGEPVAMVVAASRAEAEDAAERILVEYAPLAPVVDPLAALAPGAAAIHPELGDN
LAFARTIEAGGGAAAIDAAAERVALEFDFARHTGVTLEPRALVADWNEGEQRLTVHLGTQVPHMFQTVLATLLGLAERQI
RVIGPDVGGSFGIKIHVYPDEMAAVAASRILRRPVRFVADRLESFTGDIHARGHRVSARIGVAEDGRIEGFAVDDLTGVG
PYSAYPRTSAVEANQVINLVGGPYDFAHYAARARVVFQTKAMMSQYRAVGHPIATAVTEALVDEAARRRGIDPVEMRRRN
LIADDAYPCASPAGMRFEALSHHACLDELVRLMDYDALRAEQAGLRARGVWRGIGIASFIEITNPGAAFYGVGGARIAAQ
DGATARLDAAGDVVLHAGATEQGQGTTTILAQVTAAAMGVDPARVLVKLGDTDATPYGGGTWASRGAGVGGEAAFRAASA
LRENVLALAASILQAAPEALDIRDGAIVDAAGGAERMSLAELARIAHFRPDTLPQGVEPALVASRHYVPREYPFAFTNGV
QAAVVEVDAETGFVRLLKHFVVEDCGTIINPLLVDEQIRGGVVQGLGAALFEECRYDSEGQMLNATMADYLVPMAAEMPD
IVIGHVCTPTRESHIGAKGVGEAGTAAAAAAVLNAVNDALAPRGARITALPITPARVLEALGIG

Sequences:

>Translated_784_residues
MNGADRPIGRAMARPDARRLTQGRGLFASDIALPRMVHAAFLRSPYAHAEIRAIDLAPAREMPGVVGVFDAAALEGRCAP
WVGVLTHLKGLKSAPQYPLARGRVRFQGEPVAMVVAASRAEAEDAAERILVEYAPLAPVVDPLAALAPGAAAIHPELGDN
LAFARTIEAGGGAAAIDAAAERVALEFDFARHTGVTLEPRALVADWNEGEQRLTVHLGTQVPHMFQTVLATLLGLAERQI
RVIGPDVGGSFGIKIHVYPDEMAAVAASRILRRPVRFVADRLESFTGDIHARGHRVSARIGVAEDGRIEGFAVDDLTGVG
PYSAYPRTSAVEANQVINLVGGPYDFAHYAARARVVFQTKAMMSQYRAVGHPIATAVTEALVDEAARRRGIDPVEMRRRN
LIADDAYPCASPAGMRFEALSHHACLDELVRLMDYDALRAEQAGLRARGVWRGIGIASFIEITNPGAAFYGVGGARIAAQ
DGATARLDAAGDVVLHAGATEQGQGTTTILAQVTAAAMGVDPARVLVKLGDTDATPYGGGTWASRGAGVGGEAAFRAASA
LRENVLALAASILQAAPEALDIRDGAIVDAAGGAERMSLAELARIAHFRPDTLPQGVEPALVASRHYVPREYPFAFTNGV
QAAVVEVDAETGFVRLLKHFVVEDCGTIINPLLVDEQIRGGVVQGLGAALFEECRYDSEGQMLNATMADYLVPMAAEMPD
IVIGHVCTPTRESHIGAKGVGEAGTAAAAAAVLNAVNDALAPRGARITALPITPARVLEALGIG
>Mature_784_residues
MNGADRPIGRAMARPDARRLTQGRGLFASDIALPRMVHAAFLRSPYAHAEIRAIDLAPAREMPGVVGVFDAAALEGRCAP
WVGVLTHLKGLKSAPQYPLARGRVRFQGEPVAMVVAASRAEAEDAAERILVEYAPLAPVVDPLAALAPGAAAIHPELGDN
LAFARTIEAGGGAAAIDAAAERVALEFDFARHTGVTLEPRALVADWNEGEQRLTVHLGTQVPHMFQTVLATLLGLAERQI
RVIGPDVGGSFGIKIHVYPDEMAAVAASRILRRPVRFVADRLESFTGDIHARGHRVSARIGVAEDGRIEGFAVDDLTGVG
PYSAYPRTSAVEANQVINLVGGPYDFAHYAARARVVFQTKAMMSQYRAVGHPIATAVTEALVDEAARRRGIDPVEMRRRN
LIADDAYPCASPAGMRFEALSHHACLDELVRLMDYDALRAEQAGLRARGVWRGIGIASFIEITNPGAAFYGVGGARIAAQ
DGATARLDAAGDVVLHAGATEQGQGTTTILAQVTAAAMGVDPARVLVKLGDTDATPYGGGTWASRGAGVGGEAAFRAASA
LRENVLALAASILQAAPEALDIRDGAIVDAAGGAERMSLAELARIAHFRPDTLPQGVEPALVASRHYVPREYPFAFTNGV
QAAVVEVDAETGFVRLLKHFVVEDCGTIINPLLVDEQIRGGVVQGLGAALFEECRYDSEGQMLNATMADYLVPMAAEMPD
IVIGHVCTPTRESHIGAKGVGEAGTAAAAAAVLNAVNDALAPRGARITALPITPARVLEALGIG

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=793, Percent_Identity=24.5901639344262, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI91823271, Length=770, Percent_Identity=24.6753246753247, Blast_Score=151, Evalue=2e-36,
Organism=Escherichia coli, GI1789230, Length=777, Percent_Identity=31.4028314028314, Blast_Score=289, Evalue=4e-79,
Organism=Escherichia coli, GI1789246, Length=833, Percent_Identity=26.4105642256903, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1786478, Length=779, Percent_Identity=26.8292682926829, Blast_Score=142, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17540638, Length=739, Percent_Identity=24.6278755074425, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17539860, Length=799, Percent_Identity=23.4042553191489, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32566215, Length=793, Percent_Identity=22.5725094577554, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI17737937, Length=773, Percent_Identity=25.8732212160414, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24647199, Length=809, Percent_Identity=23.238566131026, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24647193, Length=801, Percent_Identity=23.3458177278402, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24647201, Length=809, Percent_Identity=22.7441285537701, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 82383; Mature: 82383

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGADRPIGRAMARPDARRLTQGRGLFASDIALPRMVHAAFLRSPYAHAEIRAIDLAPAR
CCCCCCCHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHH
EMPGVVGVFDAAALEGRCAPWVGVLTHLKGLKSAPQYPLARGRVRFQGEPVAMVVAASRA
HCCCCEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEEECCCC
EAEDAAERILVEYAPLAPVVDPLAALAPGAAAIHPELGDNLAFARTIEAGGGAAAIDAAA
CHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCCEEEEEEECCCCHHHHHHHH
ERVALEFDFARHTGVTLEPRALVADWNEGEQRLTVHLGTQVPHMFQTVLATLLGLAERQI
HHEEEEEEHHHCCCCEECCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCE
RVIGPDVGGSFGIKIHVYPDEMAAVAASRILRRPVRFVADRLESFTGDIHARGHRVSARI
EEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEE
GVAEDGRIEGFAVDDLTGVGPYSAYPRTSAVEANQVINLVGGPYDFAHYAARARVVFQTK
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AMMSQYRAVGHPIATAVTEALVDEAARRRGIDPVEMRRRNLIADDAYPCASPAGMRFEAL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHH
SHHACLDELVRLMDYDALRAEQAGLRARGVWRGIGIASFIEITNPGAAFYGVGGARIAAQ
HHHHHHHHHHHHHCHHHHHHHHCCCHHCCHHHHCCHHHEEEECCCCCEEEECCCCEEEEC
DGATARLDAAGDVVLHAGATEQGQGTTTILAQVTAAAMGVDPARVLVKLGDTDATPYGGG
CCCCEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCC
TWASRGAGVGGEAAFRAASALRENVLALAASILQAAPEALDIRDGAIVDAAGGAERMSLA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEECCCCHHHHHHH
ELARIAHFRPDTLPQGVEPALVASRHYVPREYPFAFTNGVQAAVVEVDAETGFVRLLKHF
HHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHH
VVEDCGTIINPLLVDEQIRGGVVQGLGAALFEECRYDSEGQMLNATMADYLVPMAAEMPD
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCC
IVIGHVCTPTRESHIGAKGVGEAGTAAAAAAVLNAVNDALAPRGARITALPITPARVLEA
CEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHH
LGIG
HCCC
>Mature Secondary Structure
MNGADRPIGRAMARPDARRLTQGRGLFASDIALPRMVHAAFLRSPYAHAEIRAIDLAPAR
CCCCCCCHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHH
EMPGVVGVFDAAALEGRCAPWVGVLTHLKGLKSAPQYPLARGRVRFQGEPVAMVVAASRA
HCCCCEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEEECCCC
EAEDAAERILVEYAPLAPVVDPLAALAPGAAAIHPELGDNLAFARTIEAGGGAAAIDAAA
CHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCCEEEEEEECCCCHHHHHHHH
ERVALEFDFARHTGVTLEPRALVADWNEGEQRLTVHLGTQVPHMFQTVLATLLGLAERQI
HHEEEEEEHHHCCCCEECCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCE
RVIGPDVGGSFGIKIHVYPDEMAAVAASRILRRPVRFVADRLESFTGDIHARGHRVSARI
EEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEE
GVAEDGRIEGFAVDDLTGVGPYSAYPRTSAVEANQVINLVGGPYDFAHYAARARVVFQTK
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AMMSQYRAVGHPIATAVTEALVDEAARRRGIDPVEMRRRNLIADDAYPCASPAGMRFEAL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHH
SHHACLDELVRLMDYDALRAEQAGLRARGVWRGIGIASFIEITNPGAAFYGVGGARIAAQ
HHHHHHHHHHHHHCHHHHHHHHCCCHHCCHHHHCCHHHEEEECCCCCEEEECCCCEEEEC
DGATARLDAAGDVVLHAGATEQGQGTTTILAQVTAAAMGVDPARVLVKLGDTDATPYGGG
CCCCEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCC
TWASRGAGVGGEAAFRAASALRENVLALAASILQAAPEALDIRDGAIVDAAGGAERMSLA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEECCCCHHHHHHH
ELARIAHFRPDTLPQGVEPALVASRHYVPREYPFAFTNGVQAAVVEVDAETGFVRLLKHF
HHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHH
VVEDCGTIINPLLVDEQIRGGVVQGLGAALFEECRYDSEGQMLNATMADYLVPMAAEMPD
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCC
IVIGHVCTPTRESHIGAKGVGEAGTAAAAAAVLNAVNDALAPRGARITALPITPARVLEA
CEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHH
LGIG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]