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The map label for this gene is cutS [H]

Identifier: 148261165

GI number: 148261165

Start: 2400519

End: 2401004

Strand: Reverse

Name: cutS [H]

Synonym: Acry_2175

Alternate gene names: 148261165

Gene position: 2401004-2400519 (Counterclockwise)

Preceding gene: 148261166

Following gene: 148261164

Centisome position: 70.84

GC content: 70.78

Gene sequence:

>486_bases
ATGTCTGGCTCCATGACGGCGATTTCCCTGATCGTGAATGGCGAGCGCGTCGAGGCCGAGGTGCCGGCCCGGCTGCATCT
GGCGGATTTCCTGCGCGAGCGGCTCGGCCTGACCGGCACGCATCTCGGCTGCGAGCATGGCGTGTGCGGCGCCTGCACGG
TGCGGCTGGACGGGGCGATCGTGCGCGGCTGCCTCGTCCTCGCGGTGCAGGCGGCGGGGTGCGTGGTCGAGACCATCGAG
GGGGTGTCGGATTCGGGCGAGCTGGCGGATTTGCAGGAGGCGTTCTGGCGCCGCAACGCGCTGCAATGCGGCTATTGCAC
GCCGGGGATGATGCTGGCGGCGGCGGATTTCCTCGCCCATGCGCCCGACCCGACCGACCGCGCGGCGATCCGCGCGCATC
TTTCGGGCAATTACTGCCGCTGCACCGGATATGAGGCGATCGTCGACGCGGTCGAGGCGACGGCGCGGGCGCGGAGGGCG
GCATGA

Upstream 100 bases:

>100_bases
CGGCACTCGCCGGGGATTTGCCGCCGCATGCGGACCCGGAGATTTCGGCGCCGGTGCGGCTGCACCTGGCGCGGGTGCTG
CTGCGGCGGGTGATGAAGGA

Downstream 100 bases:

>100_bases
ACGGCGCCGACCGGCCGATCGGACGGGCGATGGCGCGGCCGGATGCGCGGCGGCTGACCCAGGGGCGCGGGCTGTTCGCC
AGCGATATCGCGCTGCCGCG

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSGSMTAISLIVNGERVEAEVPARLHLADFLRERLGLTGTHLGCEHGVCGACTVRLDGAIVRGCLVLAVQAAGCVVETIE
GVSDSGELADLQEAFWRRNALQCGYCTPGMMLAAADFLAHAPDPTDRAAIRAHLSGNYCRCTGYEAIVDAVEATARARRA
A

Sequences:

>Translated_161_residues
MSGSMTAISLIVNGERVEAEVPARLHLADFLRERLGLTGTHLGCEHGVCGACTVRLDGAIVRGCLVLAVQAAGCVVETIE
GVSDSGELADLQEAFWRRNALQCGYCTPGMMLAAADFLAHAPDPTDRAAIRAHLSGNYCRCTGYEAIVDAVEATARARRA
A
>Mature_160_residues
SGSMTAISLIVNGERVEAEVPARLHLADFLRERLGLTGTHLGCEHGVCGACTVRLDGAIVRGCLVLAVQAAGCVVETIEG
VSDSGELADLQEAFWRRNALQCGYCTPGMMLAAADFLAHAPDPTDRAAIRAHLSGNYCRCTGYEAIVDAVEATARARRAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=166, Percent_Identity=38.5542168674699, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI71773480, Length=151, Percent_Identity=36.4238410596026, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=38.7878787878788, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1789232, Length=145, Percent_Identity=40.6896551724138, Blast_Score=108, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI32566215, Length=158, Percent_Identity=41.1392405063291, Blast_Score=116, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17539860, Length=157, Percent_Identity=40.7643312101911, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=161, Percent_Identity=38.5093167701863, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17737937, Length=165, Percent_Identity=36.969696969697, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24647193, Length=170, Percent_Identity=33.5294117647059, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24647199, Length=140, Percent_Identity=32.8571428571429, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24647201, Length=157, Percent_Identity=29.2993630573248, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=30.6748466257669, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=30.6748466257669, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16960; Mature: 16828

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSMTAISLIVNGERVEAEVPARLHLADFLRERLGLTGTHLGCEHGVCGACTVRLDGAI
CCCCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECHHH
VRGCLVLAVQAAGCVVETIEGVSDSGELADLQEAFWRRNALQCGYCTPGMMLAAADFLAH
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
APDPTDRAAIRAHLSGNYCRCTGYEAIVDAVEATARARRAA
CCCCCCHHHEEHCCCCCEEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGSMTAISLIVNGERVEAEVPARLHLADFLRERLGLTGTHLGCEHGVCGACTVRLDGAI
CCCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECHHH
VRGCLVLAVQAAGCVVETIEGVSDSGELADLQEAFWRRNALQCGYCTPGMMLAAADFLAH
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
APDPTDRAAIRAHLSGNYCRCTGYEAIVDAVEATARARRAA
CCCCCCHHHEEHCCCCCEEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]