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The map label for this gene is moeB [H]

Identifier: 148261162

GI number: 148261162

Start: 2394753

End: 2395520

Strand: Reverse

Name: moeB [H]

Synonym: Acry_2171

Alternate gene names: 148261162

Gene position: 2395520-2394753 (Counterclockwise)

Preceding gene: 148261164

Following gene: 148261161

Centisome position: 70.68

GC content: 71.48

Gene sequence:

>768_bases
ATGGATCTCGACTTCACCGAAACCGAAATCGCCCGGTATTCGCGCCACATCCTGCTGCGCGAGGTGGGCGGCACCGGGCA
GGCGCGGCTGCGCGCGGCCTCGGTGCTGATCGTCGGCGCGGGCGGGCTCGGCTCGCCGGCGGCACTTTATCTCGCGGCCG
CCGGCGTCGGGCGGATTTCCATCGTCGATGACGACGTGCTGGAACTCTCCAACCTGCAGCGGCAGATCGCGCACGGGGTG
GCGTTTCTCGGCGCGCCGAAGGTGGAGAGCGCGGCGGCGGCGATGCGCGGGCTGAACCCGGAGGTGAGCGTCAACCCGGT
CCGCGCCCGGCTGGACGCGGGGAATGTCGGCGCGCTGGTCGCCGCGCACGACATCGTGCTCGACGGGACCGACAATTTCG
CGACCCGCTTCCTCGTCGCCGATGCCTGTGTCGCGGCGCGGCGGACGCTGGTTTCGGCGGCGGTGCTGCGCTTCGAGGGG
CAGCTTTCCACCTTCAAGCCGCATGCGGGGCCGGATTGCCCCTGCTATCGGTGCCTCTATCCCGAGGCGCCGCCGGCGGG
CATGGTGCCGACCTGTTCGGAGGCCGGGGTGCTCGGCCCGGTGACGGGGGTGATGGGCACGTTGCAGGCGACGGAGGCGA
TGAAGGAGATTCTCGGCATCGGCACCTCGCTGGCCGGGCGGCTGCTGCTGTGGGACGCGCTGGATGCGCGGTTCCGCACG
ATCACGATCCCCCGCGTGCCGGACTGTGCCGCCTGTGCGGGCGTCTAG

Upstream 100 bases:

>100_bases
TGGCCGGAACATGCCGGGCGGGCCGGCCGCGATCAAGCGCGATCGGGGGCGTAGATCCGCGCCCTTGCGGCGGGGCGGCG
CGGATGCGATTCTATGCGGC

Downstream 100 bases:

>100_bases
CCGCCTCGCCCGGCTCGGGCTGGTCGTCGTGGCGCTGGCGCTCGGCGCGTGGCACGCGCCGAAGGTCGGGCCGGGACCGG
GGCCGGGCAAGGGGTCGGCC

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MDLDFTETEIARYSRHILLREVGGTGQARLRAASVLIVGAGGLGSPAALYLAAAGVGRISIVDDDVLELSNLQRQIAHGV
AFLGAPKVESAAAAMRGLNPEVSVNPVRARLDAGNVGALVAAHDIVLDGTDNFATRFLVADACVAARRTLVSAAVLRFEG
QLSTFKPHAGPDCPCYRCLYPEAPPAGMVPTCSEAGVLGPVTGVMGTLQATEAMKEILGIGTSLAGRLLLWDALDARFRT
ITIPRVPDCAACAGV

Sequences:

>Translated_255_residues
MDLDFTETEIARYSRHILLREVGGTGQARLRAASVLIVGAGGLGSPAALYLAAAGVGRISIVDDDVLELSNLQRQIAHGV
AFLGAPKVESAAAAMRGLNPEVSVNPVRARLDAGNVGALVAAHDIVLDGTDNFATRFLVADACVAARRTLVSAAVLRFEG
QLSTFKPHAGPDCPCYRCLYPEAPPAGMVPTCSEAGVLGPVTGVMGTLQATEAMKEILGIGTSLAGRLLLWDALDARFRT
ITIPRVPDCAACAGV
>Mature_255_residues
MDLDFTETEIARYSRHILLREVGGTGQARLRAASVLIVGAGGLGSPAALYLAAAGVGRISIVDDDVLELSNLQRQIAHGV
AFLGAPKVESAAAAMRGLNPEVSVNPVRARLDAGNVGALVAAHDIVLDGTDNFATRFLVADACVAARRTLVSAAVLRFEG
QLSTFKPHAGPDCPCYRCLYPEAPPAGMVPTCSEAGVLGPVTGVMGTLQATEAMKEILGIGTSLAGRLLLWDALDARFRT
ITIPRVPDCAACAGV

Specific function: Involved In The Biosynthesis Of A Demolybdo Cofactor (Molybdopterin), Necessary For Molybdoenzymes. Plays A Role In The Activation Of The Small Subunit Of The Molybdopterin Converting Factor (Moad). [C]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=249, Percent_Identity=51.8072289156626, Blast_Score=207, Evalue=8e-54,
Organism=Homo sapiens, GI38045948, Length=167, Percent_Identity=34.1317365269461, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787048, Length=249, Percent_Identity=44.9799196787149, Blast_Score=216, Evalue=9e-58,
Organism=Escherichia coli, GI87082356, Length=250, Percent_Identity=42.8, Blast_Score=166, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17540406, Length=249, Percent_Identity=44.9799196787149, Blast_Score=222, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6321903, Length=256, Percent_Identity=41.796875, Blast_Score=187, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24582879, Length=250, Percent_Identity=46, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24660640, Length=155, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26445; Mature: 26445

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLDFTETEIARYSRHILLREVGGTGQARLRAASVLIVGAGGLGSPAALYLAAAGVGRIS
CCCCCCHHHHHHHHHHHHEEECCCCCHHHEEEEEEEEEECCCCCCHHHHHHHHCCCCEEE
IVDDDVLELSNLQRQIAHGVAFLGAPKVESAAAAMRGLNPEVSVNPVRARLDAGNVGALV
EECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHEEEECCCCCEEEE
AAHDIVLDGTDNFATRFLVADACVAARRTLVSAAVLRFEGQLSTFKPHAGPDCPCYRCLY
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEC
PEAPPAGMVPTCSEAGVLGPVTGVMGTLQATEAMKEILGIGTSLAGRLLLWDALDARFRT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEHHHCCCEEE
ITIPRVPDCAACAGV
EECCCCCCHHHHCCC
>Mature Secondary Structure
MDLDFTETEIARYSRHILLREVGGTGQARLRAASVLIVGAGGLGSPAALYLAAAGVGRIS
CCCCCCHHHHHHHHHHHHEEECCCCCHHHEEEEEEEEEECCCCCCHHHHHHHHCCCCEEE
IVDDDVLELSNLQRQIAHGVAFLGAPKVESAAAAMRGLNPEVSVNPVRARLDAGNVGALV
EECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHEEEECCCCCEEEE
AAHDIVLDGTDNFATRFLVADACVAARRTLVSAAVLRFEGQLSTFKPHAGPDCPCYRCLY
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEC
PEAPPAGMVPTCSEAGVLGPVTGVMGTLQATEAMKEILGIGTSLAGRLLLWDALDARFRT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEHHHCCCEEE
ITIPRVPDCAACAGV
EECCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA