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The map label for this gene is ribBA [H]

Identifier: 148261110

GI number: 148261110

Start: 2346749

End: 2347876

Strand: Reverse

Name: ribBA [H]

Synonym: Acry_2119

Alternate gene names: 148261110

Gene position: 2347876-2346749 (Counterclockwise)

Preceding gene: 148261111

Following gene: 148261109

Centisome position: 69.27

GC content: 68.35

Gene sequence:

>1128_bases
ATGGATCAGCTCAAGACCGCATCGCTGCAGCAATACCTTGCCTCGGCCGAGGAGATCATCGAGGAAGCGCGCGCCGGGCG
GATGTTCATCCTGGTGGATGACGAGGACCGGGAAAACGAGGGCGACCTCGTGATCCCCGCCCAGTTCGCGACGCCAGACG
CCGTGAATTTCATGGCCCGGCACGCGAGGGGGCTGATCTGCCTCGCGCTGACCCGCGCGCGCTGCGAGACGCTCGGGCTC
AAGCTCATGGCGCAGTCGAACGGGTCGCGCCACGAAACCGCCTTCACGGTCTCGATCGAGGCGCGCGAGGGGGTGACCAC
CGGGATTTCCGCGGCCGACCGGGCGCGGACCATCGCGGTCGCCATCAATCCCGAATGCGGCGCCGCGGACATCGTCTCGC
CCGGCCACATCTTTCCGCTGATGGCGCGGGACGGCGGCACGCTGGTCCGCACCGGTCATACCGAGGCGGCGGTGGACATT
GCCCGCCTCGCCGGCCTCACGCCGGCCGGGGTGATCTGCGAGATCATGAACGAGGACGGGACGATGGCGCGGCTGCCGGA
CCTCGTCTCGGTCGCGCAGTACCATAATCTCAAGCTCGGGACGATCGCCGATCTGATCGCCTATCGCCGGCGGATGGAGA
AGCTGGTCCGCCGCGCGGGCGATGGAATGATCACGGATGGCGCGGGGCATCAGTGGCGCAGCGTCGTCTTCGAGAACACG
ATCGACCAGGTCGAGCACGTCGCTCTCATCAAGGGCGACATTGCCGCCGACGAGCCCGTGCTGGTGCGGATGCACGCGAT
CAGCACGATCGACGACATTCTGGGCGGCGACCATATCCGCGACCTGCGCCGGGCGATGGCGCAGATCGCCCAGTCCGGGC
GCGGGGTCGTCGTGCTCATCCGCGAGGCGCGGCCCGATGCGGTCTCCTCGCGGTTGCGGCAGATCGTCGGCGGGGCGCGC
ACCGGCGCCGTGCTGCGCGACTATGGCGTGGGCGCGCAGATCCTCGCGGATCTGGGCGTGCGCGACATGGTGCTGCTCTC
GAACCACAAGCGCGCCGTGGTCGGGCTGGAAGGCTACGGGCTCAACATTGTCGAGCAACTGCCGATCGAGGAGCCTTCGA
AGCCATGA

Upstream 100 bases:

>100_bases
AAACGCACACCAATTTCGCCACGCTGGCGGTCGGCGATGCGGTGAATATCGAAATCGACATGCTGGCCCGCTATGTCGCG
CGGCTGGCGGAGGTAGCCTG

Downstream 100 bases:

>100_bases
GCACGGCCGATGCCCCTGAAGCCGAGGTGCCGGATGTGCCTGGCCCGGCGCCGCGCATCCTGCTGATCCGCGCGCCCTAT
TACCGGCAGATCGTCGACGG

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; GTP cyclohydrolase-2; GTP cyclohydrolase II [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MDQLKTASLQQYLASAEEIIEEARAGRMFILVDDEDRENEGDLVIPAQFATPDAVNFMARHARGLICLALTRARCETLGL
KLMAQSNGSRHETAFTVSIEAREGVTTGISAADRARTIAVAINPECGAADIVSPGHIFPLMARDGGTLVRTGHTEAAVDI
ARLAGLTPAGVICEIMNEDGTMARLPDLVSVAQYHNLKLGTIADLIAYRRRMEKLVRRAGDGMITDGAGHQWRSVVFENT
IDQVEHVALIKGDIAADEPVLVRMHAISTIDDILGGDHIRDLRRAMAQIAQSGRGVVVLIREARPDAVSSRLRQIVGGAR
TGAVLRDYGVGAQILADLGVRDMVLLSNHKRAVVGLEGYGLNIVEQLPIEEPSKP

Sequences:

>Translated_375_residues
MDQLKTASLQQYLASAEEIIEEARAGRMFILVDDEDRENEGDLVIPAQFATPDAVNFMARHARGLICLALTRARCETLGL
KLMAQSNGSRHETAFTVSIEAREGVTTGISAADRARTIAVAINPECGAADIVSPGHIFPLMARDGGTLVRTGHTEAAVDI
ARLAGLTPAGVICEIMNEDGTMARLPDLVSVAQYHNLKLGTIADLIAYRRRMEKLVRRAGDGMITDGAGHQWRSVVFENT
IDQVEHVALIKGDIAADEPVLVRMHAISTIDDILGGDHIRDLRRAMAQIAQSGRGVVVLIREARPDAVSSRLRQIVGGAR
TGAVLRDYGVGAQILADLGVRDMVLLSNHKRAVVGLEGYGLNIVEQLPIEEPSKP
>Mature_375_residues
MDQLKTASLQQYLASAEEIIEEARAGRMFILVDDEDRENEGDLVIPAQFATPDAVNFMARHARGLICLALTRARCETLGL
KLMAQSNGSRHETAFTVSIEAREGVTTGISAADRARTIAVAINPECGAADIVSPGHIFPLMARDGGTLVRTGHTEAAVDI
ARLAGLTPAGVICEIMNEDGTMARLPDLVSVAQYHNLKLGTIADLIAYRRRMEKLVRRAGDGMITDGAGHQWRSVVFENT
IDQVEHVALIKGDIAADEPVLVRMHAISTIDDILGGDHIRDLRRAMAQIAQSGRGVVVLIREARPDAVSSRLRQIVGGAR
TGAVLRDYGVGAQILADLGVRDMVLLSNHKRAVVGLEGYGLNIVEQLPIEEPSKP

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=214, Percent_Identity=46.7289719626168, Blast_Score=204, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320695, Length=203, Percent_Identity=37.9310344827586, Blast_Score=149, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12; =3.5.4.25 [H]

Molecular weight: Translated: 40426; Mature: 40426

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLKTASLQQYLASAEEIIEEARAGRMFILVDDEDRENEGDLVIPAQFATPDAVNFMAR
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHH
HARGLICLALTRARCETLGLKLMAQSNGSRHETAFTVSIEAREGVTTGISAADRARTIAV
HHCCEEEEHHHHHHHHHHCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEE
AINPECGAADIVSPGHIFPLMARDGGTLVRTGHTEAAVDIARLAGLTPAGVICEIMNEDG
EECCCCCCCCCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHCCCCHHHHHEEECCCC
TMARLPDLVSVAQYHNLKLGTIADLIAYRRRMEKLVRRAGDGMITDGAGHQWRSVVFENT
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHH
IDQVEHVALIKGDIAADEPVLVRMHAISTIDDILGGDHIRDLRRAMAQIAQSGRGVVVLI
HHHHHHHHEEECCCCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEE
REARPDAVSSRLRQIVGGARTGAVLRDYGVGAQILADLGVRDMVLLSNHKRAVVGLEGYG
ECCCCHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHCCCCEEEEECCCCEEEEEECCCC
LNIVEQLPIEEPSKP
CCHHHHCCCCCCCCC
>Mature Secondary Structure
MDQLKTASLQQYLASAEEIIEEARAGRMFILVDDEDRENEGDLVIPAQFATPDAVNFMAR
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHH
HARGLICLALTRARCETLGLKLMAQSNGSRHETAFTVSIEAREGVTTGISAADRARTIAV
HHCCEEEEHHHHHHHHHHCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEE
AINPECGAADIVSPGHIFPLMARDGGTLVRTGHTEAAVDIARLAGLTPAGVICEIMNEDG
EECCCCCCCCCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHCCCCHHHHHEEECCCC
TMARLPDLVSVAQYHNLKLGTIADLIAYRRRMEKLVRRAGDGMITDGAGHQWRSVVFENT
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHH
IDQVEHVALIKGDIAADEPVLVRMHAISTIDDILGGDHIRDLRRAMAQIAQSGRGVVVLI
HHHHHHHHEEECCCCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEE
REARPDAVSSRLRQIVGGARTGAVLRDYGVGAQILADLGVRDMVLLSNHKRAVVGLEGYG
ECCCCHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHCCCCEEEEECCCCEEEEEECCCC
LNIVEQLPIEEPSKP
CCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA