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The map label for this gene is ribE [H]

Identifier: 148261111

GI number: 148261111

Start: 2347876

End: 2348490

Strand: Reverse

Name: ribE [H]

Synonym: Acry_2120

Alternate gene names: 148261111

Gene position: 2348490-2347876 (Counterclockwise)

Preceding gene: 148261112

Following gene: 148261110

Centisome position: 69.29

GC content: 68.46

Gene sequence:

>615_bases
ATGTTCACCGGGATCATCACCGGGGTTGGCGATGTGCGCGACGTGCGCCCGGCGGACAGCGTCAGCGATACGCGTCTCGT
CATCGGCGTGCCGGCGGGCAATCCCGACTGGGCCGGGATCGGCGAGGTCGCGCTCGGCGCCTCGATCGCCTGTTCGGGGT
GCTGCCTCACGGTGGTCGAGCGCGGGCCGGACTGGTTCGCCGTCGAGGTTTCCGGCGAGACGCTGTCGAAGACCACGCTC
GGCGCGTGGCGCACCGGCACCAGGATCAATCTCGAGCGCGCGCTGCGCATGGGCGACGAACTGGGCGGCCATGTCGTCTC
CGGCCATGTCGACGGGCTGGGCGAGGTGGTGTCGATGCGGCCGGAGGGCGGCTCGACGCGCTGGCGCTTCCGGGTGTCGC
GGGAACTGGCCCGCTTCATCGCGCCGAAGGGCAGCGTTGCGGTGAACGGTGTCTCGCTGACGGTGAACGAGGTTGACGGC
ACTGAATTCGGGGTGAACATCATCCCGCACACGGAAACGCACACCAATTTCGCCACGCTGGCGGTCGGCGATGCGGTGAA
TATCGAAATCGACATGCTGGCCCGCTATGTCGCGCGGCTGGCGGAGGTAGCCTGA

Upstream 100 bases:

>100_bases
CTTCGGTGTGGAGGAGTTGGGCCGGGCGGCGCGTTTCACGCGCATCGACGCGTCGGTTTGCGGCGGCGACATCCGCACGC
GCTATCGGAGGGATTGAACG

Downstream 100 bases:

>100_bases
TGGATCAGCTCAAGACCGCATCGCTGCAGCAATACCTTGCCTCGGCCGAGGAGATCATCGAGGAAGCGCGCGCCGGGCGG
ATGTTCATCCTGGTGGATGA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MFTGIITGVGDVRDVRPADSVSDTRLVIGVPAGNPDWAGIGEVALGASIACSGCCLTVVERGPDWFAVEVSGETLSKTTL
GAWRTGTRINLERALRMGDELGGHVVSGHVDGLGEVVSMRPEGGSTRWRFRVSRELARFIAPKGSVAVNGVSLTVNEVDG
TEFGVNIIPHTETHTNFATLAVGDAVNIEIDMLARYVARLAEVA

Sequences:

>Translated_204_residues
MFTGIITGVGDVRDVRPADSVSDTRLVIGVPAGNPDWAGIGEVALGASIACSGCCLTVVERGPDWFAVEVSGETLSKTTL
GAWRTGTRINLERALRMGDELGGHVVSGHVDGLGEVVSMRPEGGSTRWRFRVSRELARFIAPKGSVAVNGVSLTVNEVDG
TEFGVNIIPHTETHTNFATLAVGDAVNIEIDMLARYVARLAEVA
>Mature_204_residues
MFTGIITGVGDVRDVRPADSVSDTRLVIGVPAGNPDWAGIGEVALGASIACSGCCLTVVERGPDWFAVEVSGETLSKTTL
GAWRTGTRINLERALRMGDELGGHVVSGHVDGLGEVVSMRPEGGSTRWRFRVSRELARFIAPKGSVAVNGVSLTVNEVDG
TEFGVNIIPHTETHTNFATLAVGDAVNIEIDMLARYVARLAEVA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=204, Percent_Identity=35.2941176470588, Blast_Score=111, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319733, Length=204, Percent_Identity=35.7843137254902, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21502; Mature: 21502

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIITGVGDVRDVRPADSVSDTRLVIGVPAGNPDWAGIGEVALGASIACSGCCLTVVE
CCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCEECCCEEEEEEE
RGPDWFAVEVSGETLSKTTLGAWRTGTRINLERALRMGDELGGHVVSGHVDGLGEVVSMR
CCCCEEEEEECCCEECCCCCCCCCCCCEECHHHHHHHHHHCCCEEEECCCCCCCCEEEEC
PEGGSTRWRFRVSRELARFIAPKGSVAVNGVSLTVNEVDGTEFGVNIIPHTETHTNFATL
CCCCCCEEEEEHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEECEEEEECCCCCCCEEEE
AVGDAVNIEIDMLARYVARLAEVA
EECCEEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTGIITGVGDVRDVRPADSVSDTRLVIGVPAGNPDWAGIGEVALGASIACSGCCLTVVE
CCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCEECCCEEEEEEE
RGPDWFAVEVSGETLSKTTLGAWRTGTRINLERALRMGDELGGHVVSGHVDGLGEVVSMR
CCCCEEEEEECCCEECCCCCCCCCCCCEECHHHHHHHHHHCCCEEEECCCCCCCCEEEEC
PEGGSTRWRFRVSRELARFIAPKGSVAVNGVSLTVNEVDGTEFGVNIIPHTETHTNFATL
CCCCCCEEEEEHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEECEEEEECCCCCCCEEEE
AVGDAVNIEIDMLARYVARLAEVA
EECCEEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]