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The map label for this gene is ribH [H]

Identifier: 148261109

GI number: 148261109

Start: 2346270

End: 2346752

Strand: Reverse

Name: ribH [H]

Synonym: Acry_2118

Alternate gene names: 148261109

Gene position: 2346752-2346270 (Counterclockwise)

Preceding gene: 148261110

Following gene: 148261108

Centisome position: 69.24

GC content: 70.6

Gene sequence:

>483_bases
ATGAGCACGGCCGATGCCCCTGAAGCCGAGGTGCCGGATGTGCCTGGCCCGGCGCCGCGCATCCTGCTGATCCGCGCGCC
CTATTACCGGCAGATCGTCGACGGCATGACGGATGCGGCGGTGCTGCTCCTCGGCCGGGCGAATGCGACGGTCGAGACGG
TCGACGTCGCCGGCGCGTTCGAGCTGCCGCAGGCGCTCGCCATCGCGCTGCGCGGGCGGACGCGCTACGATGGCTATGTG
GCGCTCGGCTGCGTCGTGCGCGGCGAGACGGACCATTACGATTTCATCTGCGATTCGGCGATGAACGGGCTGATGCAGGT
GGCGATCGACTATGCGGCGCCGCTCGGGACGGCGCTGCTGACCGTCGATACCCTGGCTCAGGCGGAGGCGCGCTCGGCCG
AGACCGGATCGAACAAGGGGGCCGAGGCGGCATCGGCCTGTCTGCGGCAGATCGCCCTCGCGCGTCGTCTGGGGGCGGCA
TGA

Upstream 100 bases:

>100_bases
ACATGGTGCTGCTCTCGAACCACAAGCGCGCCGTGGTCGGGCTGGAAGGCTACGGGCTCAACATTGTCGAGCAACTGCCG
ATCGAGGAGCCTTCGAAGCC

Downstream 100 bases:

>100_bases
AACCGGCGGGAAGCAAGGCGCGGCCGCGCACGCTCGCCCGCGCCGCGGCGGTGCAGGCGCTCTACCAGTGCGAGCATGCC
GGCGAGACGGCCGAAACCGT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSTADAPEAEVPDVPGPAPRILLIRAPYYRQIVDGMTDAAVLLLGRANATVETVDVAGAFELPQALAIALRGRTRYDGYV
ALGCVVRGETDHYDFICDSAMNGLMQVAIDYAAPLGTALLTVDTLAQAEARSAETGSNKGAEAASACLRQIALARRLGAA

Sequences:

>Translated_160_residues
MSTADAPEAEVPDVPGPAPRILLIRAPYYRQIVDGMTDAAVLLLGRANATVETVDVAGAFELPQALAIALRGRTRYDGYV
ALGCVVRGETDHYDFICDSAMNGLMQVAIDYAAPLGTALLTVDTLAQAEARSAETGSNKGAEAASACLRQIALARRLGAA
>Mature_159_residues
STADAPEAEVPDVPGPAPRILLIRAPYYRQIVDGMTDAAVLLLGRANATVETVDVAGAFELPQALAIALRGRTRYDGYVA
LGCVVRGETDHYDFICDSAMNGLMQVAIDYAAPLGTALLTVDTLAQAEARSAETGSNKGAEAASACLRQIALARRLGAA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=151, Percent_Identity=35.0993377483444, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16692; Mature: 16561

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTADAPEAEVPDVPGPAPRILLIRAPYYRQIVDGMTDAAVLLLGRANATVETVDVAGAF
CCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHCCCCHHHHEEEECCCCEEEEEECCCCH
ELPQALAIALRGRTRYDGYVALGCVVRGETDHYDFICDSAMNGLMQVAIDYAAPLGTALL
HHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVDTLAQAEARSAETGSNKGAEAASACLRQIALARRLGAA
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STADAPEAEVPDVPGPAPRILLIRAPYYRQIVDGMTDAAVLLLGRANATVETVDVAGAF
CCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHCCCCHHHHEEEECCCCEEEEEECCCCH
ELPQALAIALRGRTRYDGYVALGCVVRGETDHYDFICDSAMNGLMQVAIDYAAPLGTALL
HHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVDTLAQAEARSAETGSNKGAEAASACLRQIALARRLGAA
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA