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The map label for this gene is trpS [H]

Identifier: 148242544

GI number: 148242544

Start: 1284745

End: 1285767

Strand: Direct

Name: trpS [H]

Synonym: SynRCC307_1445

Alternate gene names: 148242544

Gene position: 1284745-1285767 (Clockwise)

Preceding gene: 148242543

Following gene: 148242545

Centisome position: 57.74

GC content: 61.88

Gene sequence:

>1023_bases
ATGGCAAGACCCAGGGTGCTGTCGGGTGTTCAGCCCACAGGGTCTTTGCATCTCGGCAACTGGCTTGGAGCCATCCGCAA
TTGGGTGGACCTGCAACGCAGCCACGACACCTTCTTTTGTGTTGTGGACCTCCATGCCATCACGGTCCCCCACGACCCGA
AGCAACTCGCCGCCGACACGCGCTCGACGGCAGCGCTCTATTTGGCCTGCGGCATCGATCCGGAGCAGGCCACTGTTTTC
GTGCAGAGCCAGGTCCCCGCGCACGCGGAACTGGCGTGGCTCCTCAACTGCGTCACGCCGCTGAACTGGCTTGAGCGAAT
GATCCAGTTCAAGGAAAAAGCCGTTAAGCAGGGCGACAACGTGTCCGTGGGCCTGCTGGATTACCCGGTGTTGATGGCCG
CCGACATCCTTCTCTATGACGCCGACCAAGTGCCGGTTGGCGAAGATCAAAAACAGCACCTCGAACTCGCCCGAGACATT
GCGCAGCAGAGGATCAATAGCCGCTTTGGCAGCGAGGAGACGCCGGTGCTCAAGGTCCCCAAACCGATGATCATGAAAGA
GGGGGCCCGTGTGATGAGCCTCACCGATGGCAGCGCCAAGATGAGCAAAAGCGATCCCAACGAGGGGGCACGGATCAACC
TGCTCGATCCACCGGAGCTGATCACCAAGAAGATCAAGCGCGCCAAAACCGACCCGGTGATGGGCTTGGAATTCGGCAAC
CCTGAGCGCCCTGAGGCCGACAACCTGCTTGGGCTCTATGCGCTACTCAGCGGCCAGAGCCGTGAGCAGGTGTCCAGCGA
ATGTGCCGAGATGGGCTGGGGACGCTTCAAACCCCTGCTCGCCGAGACCACGGTGGAGGCCCTCAGGCCGATTCAGCAGC
GTTACAGCGAAATCAGCGCTGACCGCAGCGGCCTCGATCAGGTTCTGGCGGCGGGGCGGGAACGGGCCAGCGCAGTGGCC
GAGCAAACCCTGCAACGGGTTCAAGAGGCCATGGGCTTCGCCAGACCCGCGACAGCTAATTAG

Upstream 100 bases:

>100_bases
AAGAGACAACAACGGAATCAGCAGCGGCCAGCGAAGAAGCCAGCGAAGAAGCCAGCACCGAAGCGGCCAGCGAGGCCACT
AGCACCGAAGCGGAGGCCTG

Downstream 100 bases:

>100_bases
TTTCTGAAGCAAAGATAAACAGAGGTAATCATTGGGCGCCTCGGCGGCCGTCCTCATCAAACCCTCAGACGCCGATACCC
CTGATCTCAACTCTGTCGCA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MARPRVLSGVQPTGSLHLGNWLGAIRNWVDLQRSHDTFFCVVDLHAITVPHDPKQLAADTRSTAALYLACGIDPEQATVF
VQSQVPAHAELAWLLNCVTPLNWLERMIQFKEKAVKQGDNVSVGLLDYPVLMAADILLYDADQVPVGEDQKQHLELARDI
AQQRINSRFGSEETPVLKVPKPMIMKEGARVMSLTDGSAKMSKSDPNEGARINLLDPPELITKKIKRAKTDPVMGLEFGN
PERPEADNLLGLYALLSGQSREQVSSECAEMGWGRFKPLLAETTVEALRPIQQRYSEISADRSGLDQVLAAGRERASAVA
EQTLQRVQEAMGFARPATAN

Sequences:

>Translated_340_residues
MARPRVLSGVQPTGSLHLGNWLGAIRNWVDLQRSHDTFFCVVDLHAITVPHDPKQLAADTRSTAALYLACGIDPEQATVF
VQSQVPAHAELAWLLNCVTPLNWLERMIQFKEKAVKQGDNVSVGLLDYPVLMAADILLYDADQVPVGEDQKQHLELARDI
AQQRINSRFGSEETPVLKVPKPMIMKEGARVMSLTDGSAKMSKSDPNEGARINLLDPPELITKKIKRAKTDPVMGLEFGN
PERPEADNLLGLYALLSGQSREQVSSECAEMGWGRFKPLLAETTVEALRPIQQRYSEISADRSGLDQVLAAGRERASAVA
EQTLQRVQEAMGFARPATAN
>Mature_339_residues
ARPRVLSGVQPTGSLHLGNWLGAIRNWVDLQRSHDTFFCVVDLHAITVPHDPKQLAADTRSTAALYLACGIDPEQATVFV
QSQVPAHAELAWLLNCVTPLNWLERMIQFKEKAVKQGDNVSVGLLDYPVLMAADILLYDADQVPVGEDQKQHLELARDIA
QQRINSRFGSEETPVLKVPKPMIMKEGARVMSLTDGSAKMSKSDPNEGARINLLDPPELITKKIKRAKTDPVMGLEFGNP
ERPEADNLLGLYALLSGQSREQVSSECAEMGWGRFKPLLAETTVEALRPIQQRYSEISADRSGLDQVLAAGRERASAVAE
QTLQRVQEAMGFARPATAN

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=42.042042042042, Blast_Score=267, Evalue=1e-71,
Organism=Homo sapiens, GI41352700, Length=176, Percent_Identity=52.2727272727273, Blast_Score=185, Evalue=5e-47,
Organism=Escherichia coli, GI1789786, Length=341, Percent_Identity=48.6803519061584, Blast_Score=320, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI71982800, Length=336, Percent_Identity=36.0119047619048, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71982793, Length=336, Percent_Identity=36.0119047619048, Blast_Score=194, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6320474, Length=349, Percent_Identity=38.6819484240688, Blast_Score=221, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24666151, Length=337, Percent_Identity=45.1038575667656, Blast_Score=271, Evalue=5e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37441; Mature: 37310

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPRVLSGVQPTGSLHLGNWLGAIRNWVDLQRSHDTFFCVVDLHAITVPHDPKQLAADT
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHCC
RSTAALYLACGIDPEQATVFVQSQVPAHAELAWLLNCVTPLNWLERMIQFKEKAVKQGDN
CCCEEEEEEECCCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VSVGLLDYPVLMAADILLYDADQVPVGEDQKQHLELARDIAQQRINSRFGSEETPVLKVP
CEEEHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
KPMIMKEGARVMSLTDGSAKMSKSDPNEGARINLLDPPELITKKIKRAKTDPVMGLEFGN
CHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCC
PERPEADNLLGLYALLSGQSREQVSSECAEMGWGRFKPLLAETTVEALRPIQQRYSEISA
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
DRSGLDQVLAAGRERASAVAEQTLQRVQEAMGFARPATAN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ARPRVLSGVQPTGSLHLGNWLGAIRNWVDLQRSHDTFFCVVDLHAITVPHDPKQLAADT
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHCC
RSTAALYLACGIDPEQATVFVQSQVPAHAELAWLLNCVTPLNWLERMIQFKEKAVKQGDN
CCCEEEEEEECCCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VSVGLLDYPVLMAADILLYDADQVPVGEDQKQHLELARDIAQQRINSRFGSEETPVLKVP
CEEEHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
KPMIMKEGARVMSLTDGSAKMSKSDPNEGARINLLDPPELITKKIKRAKTDPVMGLEFGN
CHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCC
PERPEADNLLGLYALLSGQSREQVSSECAEMGWGRFKPLLAETTVEALRPIQQRYSEISA
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
DRSGLDQVLAAGRERASAVAEQTLQRVQEAMGFARPATAN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]