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The map label for this gene is cysH [H]

Identifier: 148241489

GI number: 148241489

Start: 370160

End: 370876

Strand: Direct

Name: cysH [H]

Synonym: SynRCC307_0390

Alternate gene names: 148241489

Gene position: 370160-370876 (Clockwise)

Preceding gene: 148241486

Following gene: 148241490

Centisome position: 16.64

GC content: 62.2

Gene sequence:

>717_bases
GTGCAGCTGGTTCAGGATCTGGAAGCCACCCAGGCTGAGCTGGAGGCGCTTGAGGCCCCTGAGCAATTGCGCTGGGCCAA
TGATCATTTCGGCAGCGGCTTTGCTGTCACCACCAGCTTTGGCACCCAGTCAGCCGTTTTGCTGCATCTGTTGGTGGCTG
TGGCGCCAGATGTGCCCGTCTACTGGATTGATACGGGGTATCTATTCCCTGAGACCTACCAATACGCCGCGGATTTAACG
CAGCGCCTCAAGCTGAATCTCAAGGTGGTGCAGCCTGAGTTGAGCCCAGCGCGCATGGAAGCGCTGCTCGGCCGGCTTTG
GGAGAGCGAAAACCCCGACGACCTGGTGACCTACCACCGGCTGCGCAAGGTGGAGCCCTTGGATCAGGCCTTGGATGCTG
CTGAGGTGAGCTGCTGGGCTAGCGGTGTGCGGGCTGGTCAAACTGATAACCGCGCCGCCATGCGGCCGCTGGAGCGTTTG
CGCGGGCGTTGGAGTTTGCGGCCGCTGCTGCGCTGGACCCGGCGCGACGTCTACTACTACATGGAGAAGCACGAGCTGCC
TCAACATCCCCTGTTCGAGCAGGGCTACAGCACCGTGGGTGACTGGCACTCCAGTGCACCCGACGATGGTTTGGGTCGGG
CTAGCCGCTTTGGCGGTCGCCATCAGGAGTGCGGCTTGCATCTGCCGGAACCTTTGGTGGAAGGCGCCGGGATTTGA

Upstream 100 bases:

>100_bases
TCACGATGGGAGAGGTCACCGTTTGCTCGGAACTGGGGCGAGGCTAAGAGGCCAGAGCCGGGTGATGCGGCAGGCTGTCT
AGAGCTGGGGAGGGTCTGCG

Downstream 100 bases:

>100_bases
GCGATGCGGCGTTGGCTGCTGATTGGCAACAGCCGCTGGCATTGGGCGGCTCTGGCGCCTGATCAGTCGCTTCAGCTCTG
GCACACCAGTGCGGCCGCTG

Product: phosphoadenosine phosphosulfate reductase (PAPS reductase)

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MQLVQDLEATQAELEALEAPEQLRWANDHFGSGFAVTTSFGTQSAVLLHLLVAVAPDVPVYWIDTGYLFPETYQYAADLT
QRLKLNLKVVQPELSPARMEALLGRLWESENPDDLVTYHRLRKVEPLDQALDAAEVSCWASGVRAGQTDNRAAMRPLERL
RGRWSLRPLLRWTRRDVYYYMEKHELPQHPLFEQGYSTVGDWHSSAPDDGLGRASRFGGRHQECGLHLPEPLVEGAGI

Sequences:

>Translated_238_residues
MQLVQDLEATQAELEALEAPEQLRWANDHFGSGFAVTTSFGTQSAVLLHLLVAVAPDVPVYWIDTGYLFPETYQYAADLT
QRLKLNLKVVQPELSPARMEALLGRLWESENPDDLVTYHRLRKVEPLDQALDAAEVSCWASGVRAGQTDNRAAMRPLERL
RGRWSLRPLLRWTRRDVYYYMEKHELPQHPLFEQGYSTVGDWHSSAPDDGLGRASRFGGRHQECGLHLPEPLVEGAGI
>Mature_238_residues
MQLVQDLEATQAELEALEAPEQLRWANDHFGSGFAVTTSFGTQSAVLLHLLVAVAPDVPVYWIDTGYLFPETYQYAADLT
QRLKLNLKVVQPELSPARMEALLGRLWESENPDDLVTYHRLRKVEPLDQALDAAEVSCWASGVRAGQTDNRAAMRPLERL
RGRWSLRPLLRWTRRDVYYYMEKHELPQHPLFEQGYSTVGDWHSSAPDDGLGRASRFGGRHQECGLHLPEPLVEGAGI

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=223, Percent_Identity=41.7040358744395, Blast_Score=178, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6325425, Length=249, Percent_Identity=28.5140562248996, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26934; Mature: 26934

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLVQDLEATQAELEALEAPEQLRWANDHFGSGFAVTTSFGTQSAVLLHLLVAVAPDVPV
CCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCE
YWIDTGYLFPETYQYAADLTQRLKLNLKVVQPELSPARMEALLGRLWESENPDDLVTYHR
EEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
LRKVEPLDQALDAAEVSCWASGVRAGQTDNRAAMRPLERLRGRWSLRPLLRWTRRDVYYY
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MEKHELPQHPLFEQGYSTVGDWHSSAPDDGLGRASRFGGRHQECGLHLPEPLVEGAGI
HHHHCCCCCCCHHHCCHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MQLVQDLEATQAELEALEAPEQLRWANDHFGSGFAVTTSFGTQSAVLLHLLVAVAPDVPV
CCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCE
YWIDTGYLFPETYQYAADLTQRLKLNLKVVQPELSPARMEALLGRLWESENPDDLVTYHR
EEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
LRKVEPLDQALDAAEVSCWASGVRAGQTDNRAAMRPLERLRGRWSLRPLLRWTRRDVYYY
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MEKHELPQHPLFEQGYSTVGDWHSSAPDDGLGRASRFGGRHQECGLHLPEPLVEGAGI
HHHHCCCCCCCHHHCCHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1463852 [H]