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The map label for this gene is epd [H]

Identifier: 229259769

GI number: 229259769

Start: 25031

End: 26056

Strand: Direct

Name: epd [H]

Synonym: VC0395_A0029

Alternate gene names: 229259769

Gene position: 25031-26056 (Clockwise)

Preceding gene: 147674899

Following gene: 147673541

Centisome position: 0.83

GC content: 46.0

Gene sequence:

>1026_bases
ATGCTGAGGGTAGCAATTAACGGCTTTGGGCGCATTGGGCGTAATGTGTTACGCGCTGTGTATGAAAGTGGTAAACGTGA
CCGCATTCAAGTGGTTGCGGTGAACGAGCTTGCCAAGCCAGATGCGATGGCACACCTCCTGCAGTACGATACGAGCCACG
GTCGCTTTGGCAAAAAAATCAGCCATGATCAGCAGCATATCTATGTTCACCATCAAAATGGTGAGTATGACTCAATCCGC
ATTCTGCATCTTTCGGAAATTCCTCTCTTACCTTGGCGTGATTTAGGCGTGGATTTAGTCCTCGACTGCACAGGTGTGTA
TGGTTGCCAAGAGGATGGTCAGCAACATATTGATGCGGGCGCGAAGTTAGTTTTATTTTCCCATCCTGGTGCTAGCGATC
TCGACAACACCATCATCTATGGCGTGAATCATGAGACGCTCACTGCTGAGCATAAAATCGTCTCTAACGGTTCTTGTACC
ACCAACTGCATTGTGCCCATCATCAAGGTATTGGATGACGCATTCGGCATTGATTCTGGCACCATCACCACCATCCATTC
CTCGATGAACGATCAACAAGTGATTGATGCGTATCATAATGACTTACGACGCACACGAGCGGCCAGTCAATCTATCATTC
CGGTTGATACTAAGTTGCATAAAGGTATTGAAAGAATATTTCCGAAATTTTCTAACAAATTTGAAGCGATTTCGGTGCGT
GTACCAACAGTAAATGTGACCGCGATGGATTTAAGTGTCACAATTAAATCAAATGTGAAAGTTAATGACGTAAATCAAAC
CATTGTGAACGCATCTCAGTGTACATTACGTGGCATTGTTGACTATACTGAAGCGCCTTTGGTTTCCATCGATTTTAACC
ACGATCCGCACAGCGCGATTGTGGATGGGACGCAAACGAGAGTCAGTAACGGGCAGTTAGTAAAAATGCTCGTTTGGTGT
GATAACGAATGGGGCTTTGCCAACCGGATGTTAGATACCGCATTGGCAATGCAGGCCACGCAGTAG

Upstream 100 bases:

>100_bases
CGATCGGCGGTGGAATCATTTATTGCACAGGATCGCCGTGCCAAAGCCTAGAGTATCGGTTACTATTGCCAACCAATCTG
AGAGCGATAGGCGAGATACG

Downstream 100 bases:

>100_bases
CGGCTAAGCATGCACTTCAAATCAGGTTTGAACATTGAAACCCGAAGGACGCATCCCCATATCGGTGAACAGCTAAGATT
TTACCGACTCGGCAGGGTCG

Product: erythrose 4-phosphate dehydrogenase

Products: NA

Alternate protein names: E4PDH [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MLRVAINGFGRIGRNVLRAVYESGKRDRIQVVAVNELAKPDAMAHLLQYDTSHGRFGKKISHDQQHIYVHHQNGEYDSIR
ILHLSEIPLLPWRDLGVDLVLDCTGVYGCQEDGQQHIDAGAKLVLFSHPGASDLDNTIIYGVNHETLTAEHKIVSNGSCT
TNCIVPIIKVLDDAFGIDSGTITTIHSSMNDQQVIDAYHNDLRRTRAASQSIIPVDTKLHKGIERIFPKFSNKFEAISVR
VPTVNVTAMDLSVTIKSNVKVNDVNQTIVNASQCTLRGIVDYTEAPLVSIDFNHDPHSAIVDGTQTRVSNGQLVKMLVWC
DNEWGFANRMLDTALAMQATQ

Sequences:

>Translated_341_residues
MLRVAINGFGRIGRNVLRAVYESGKRDRIQVVAVNELAKPDAMAHLLQYDTSHGRFGKKISHDQQHIYVHHQNGEYDSIR
ILHLSEIPLLPWRDLGVDLVLDCTGVYGCQEDGQQHIDAGAKLVLFSHPGASDLDNTIIYGVNHETLTAEHKIVSNGSCT
TNCIVPIIKVLDDAFGIDSGTITTIHSSMNDQQVIDAYHNDLRRTRAASQSIIPVDTKLHKGIERIFPKFSNKFEAISVR
VPTVNVTAMDLSVTIKSNVKVNDVNQTIVNASQCTLRGIVDYTEAPLVSIDFNHDPHSAIVDGTQTRVSNGQLVKMLVWC
DNEWGFANRMLDTALAMQATQ
>Mature_341_residues
MLRVAINGFGRIGRNVLRAVYESGKRDRIQVVAVNELAKPDAMAHLLQYDTSHGRFGKKISHDQQHIYVHHQNGEYDSIR
ILHLSEIPLLPWRDLGVDLVLDCTGVYGCQEDGQQHIDAGAKLVLFSHPGASDLDNTIIYGVNHETLTAEHKIVSNGSCT
TNCIVPIIKVLDDAFGIDSGTITTIHSSMNDQQVIDAYHNDLRRTRAASQSIIPVDTKLHKGIERIFPKFSNKFEAISVR
VPTVNVTAMDLSVTIKSNVKVNDVNQTIVNASQCTLRGIVDYTEAPLVSIDFNHDPHSAIVDGTQTRVSNGQLVKMLVWC
DNEWGFANRMLDTALAMQATQ

Specific function: Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=346, Percent_Identity=36.7052023121387, Blast_Score=235, Evalue=5e-62,
Organism=Homo sapiens, GI7657116, Length=334, Percent_Identity=35.6287425149701, Blast_Score=213, Evalue=2e-55,
Organism=Escherichia coli, GI1789295, Length=336, Percent_Identity=69.6428571428571, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=38.0239520958084, Blast_Score=238, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17534677, Length=332, Percent_Identity=37.3493975903614, Blast_Score=240, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI17534679, Length=332, Percent_Identity=37.0481927710843, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI32566163, Length=332, Percent_Identity=37.3493975903614, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=37.3493975903614, Blast_Score=233, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=39.5833333333333, Blast_Score=256, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=38.9221556886228, Blast_Score=255, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=39.2215568862275, Blast_Score=254, Evalue=1e-68,
Organism=Drosophila melanogaster, GI19922412, Length=340, Percent_Identity=36.1764705882353, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI85725000, Length=341, Percent_Identity=34.6041055718475, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI22023983, Length=341, Percent_Identity=34.6041055718475, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI17933600, Length=341, Percent_Identity=34.0175953079179, Blast_Score=218, Evalue=5e-57,
Organism=Drosophila melanogaster, GI18110149, Length=341, Percent_Identity=34.0175953079179, Blast_Score=218, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006422
- InterPro:   IPR020831
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.72 [H]

Molecular weight: Translated: 37773; Mature: 37773

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRVAINGFGRIGRNVLRAVYESGKRDRIQVVAVNELAKPDAMAHLLQYDTSHGRFGKKI
CEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
SHDQQHIYVHHQNGEYDSIRILHLSEIPLLPWRDLGVDLVLDCTGVYGCQEDGQQHIDAG
CCCCEEEEEEECCCCCCCEEEEEECCCCCCCCHHCCEEEEEEECCCCCCCCCCHHHHCCC
AKLVLFSHPGASDLDNTIIYGVNHETLTAEHKIVSNGSCTTNCIVPIIKVLDDAFGIDSG
CEEEEEECCCCCCCCCCEEEECCCCEEEECEEEECCCCCCHHHHHHHHHHHHHHHCCCCC
TITTIHSSMNDQQVIDAYHNDLRRTRAASQSIIPVDTKLHKGIERIFPKFSNKFEAISVR
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE
VPTVNVTAMDLSVTIKSNVKVNDVNQTIVNASQCTLRGIVDYTEAPLVSIDFNHDPHSAI
ECEEEEEEEEEEEEEECCEEEECCHHHHHCCCHHEEEEEECCCCCCEEEEECCCCCCCCE
VDGTQTRVSNGQLVKMLVWCDNEWGFANRMLDTALAMQATQ
ECCCCEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRVAINGFGRIGRNVLRAVYESGKRDRIQVVAVNELAKPDAMAHLLQYDTSHGRFGKKI
CEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
SHDQQHIYVHHQNGEYDSIRILHLSEIPLLPWRDLGVDLVLDCTGVYGCQEDGQQHIDAG
CCCCEEEEEEECCCCCCCEEEEEECCCCCCCCHHCCEEEEEEECCCCCCCCCCHHHHCCC
AKLVLFSHPGASDLDNTIIYGVNHETLTAEHKIVSNGSCTTNCIVPIIKVLDDAFGIDSG
CEEEEEECCCCCCCCCCEEEECCCCEEEECEEEECCCCCCHHHHHHHHHHHHHHHCCCCC
TITTIHSSMNDQQVIDAYHNDLRRTRAASQSIIPVDTKLHKGIERIFPKFSNKFEAISVR
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE
VPTVNVTAMDLSVTIKSNVKVNDVNQTIVNASQCTLRGIVDYTEAPLVSIDFNHDPHSAI
ECEEEEEEEEEEEEEECCEEEECCHHHHHCCCHHEEEEEECCCCCCEEEEECCCCCCCCE
VDGTQTRVSNGQLVKMLVWCDNEWGFANRMLDTALAMQATQ
ECCCCEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA