Click here to switch to the map view.

The map label for this gene is argB

Identifier: 147675582

GI number: 147675582

Start: 2369091

End: 2369879

Strand: Reverse

Name: argB

Synonym: VC0395_A2219

Alternate gene names: 147675582

Gene position: 2369879-2369091 (Counterclockwise)

Preceding gene: 147675531

Following gene: 147673961

Centisome position: 78.37

GC content: 53.61

Gene sequence:

>789_bases
ATGTCAGATCTTAAGCTCAGTCCTTTAGTGATTAAGTTAGGCGGTGCGGCGCTCGATTGCGCAGAGACACTTAGCAAATT
GTTTGGTGCGATTGCCCAATACCAGAACCAAGCCCAACGACGCATCGTGATCGTGCATGGCGGTGGTTATCTGGTCGACG
ACTTGATGGCGAAGCTGCAACTCAAATCGGTCAAGAAAGACGGTTTGCGCGTCACTCCGTATGATCAAATTCCGATCATT
GCCGGCGCTCTCGCAGGTACAGCCAACAAGATGCTGCAAGGCCAAGCGATCAAAGATGGCATCAATGCCGTAGGTTTGTC
ACTGGCGGATGGTGGTTTGTGCCACGTCGAGGAATTAGATCCTGAACTGGGCGCAGTCGGTAAAGCCACGCCGGGAGATT
CCACTTTGCTGCAAGCGATTTTGGCTACCGGTGCGATGCCCATCATTAGCTCGATTGGCCTAACTGCGCAAGGGCAGATG
ATGAACGTCAACGCTGATCAAGCGGCGGTGGCTGTGGCGGGTGCTCTGGATGCGGAATTGGTCCTGCTCTCGGATGTCAG
CGGTGTACTGGATGGCAAAGGCCACCTCATCGCCACCTTAGATGCTAAACAAGCGGATGCACTGATTGCCGGCAAAGTGA
TTACCGACGGCATGATCGTCAAAGTGAAAGCGGCATTGGAAGCGGCGCAAGATTTAGGACGTCCGATTGAAGTGGCTACC
TGGCGTTACCCAGAGAAGCTCGCCAAGTTATTTGGCGGCGAAAGCATCGGCACCCGTTTTCTACCTTAA

Upstream 100 bases:

>100_bases
TATCGACAATTTATTGAAAGGCGCATCGAGTCAAGCGATGCAGTGTTTAAATATTCACTACGGTTTCGATGAATTAACCG
CGTTGGTGTAAGGGTTCAAC

Downstream 100 bases:

>100_bases
GATTTTAAGTCACTAATTTGATTAAACCTGAGCACTGACCGCCAAGCGCAGAGCCAGGAATATGGAGATACATCAATGAG
TAAAGTACAAGTTAAAAAAG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSDLKLSPLVIKLGGAALDCAETLSKLFGAIAQYQNQAQRRIVIVHGGGYLVDDLMAKLQLKSVKKDGLRVTPYDQIPII
AGALAGTANKMLQGQAIKDGINAVGLSLADGGLCHVEELDPELGAVGKATPGDSTLLQAILATGAMPIISSIGLTAQGQM
MNVNADQAAVAVAGALDAELVLLSDVSGVLDGKGHLIATLDAKQADALIAGKVITDGMIVKVKAALEAAQDLGRPIEVAT
WRYPEKLAKLFGGESIGTRFLP

Sequences:

>Translated_262_residues
MSDLKLSPLVIKLGGAALDCAETLSKLFGAIAQYQNQAQRRIVIVHGGGYLVDDLMAKLQLKSVKKDGLRVTPYDQIPII
AGALAGTANKMLQGQAIKDGINAVGLSLADGGLCHVEELDPELGAVGKATPGDSTLLQAILATGAMPIISSIGLTAQGQM
MNVNADQAAVAVAGALDAELVLLSDVSGVLDGKGHLIATLDAKQADALIAGKVITDGMIVKVKAALEAAQDLGRPIEVAT
WRYPEKLAKLFGGESIGTRFLP
>Mature_261_residues
SDLKLSPLVIKLGGAALDCAETLSKLFGAIAQYQNQAQRRIVIVHGGGYLVDDLMAKLQLKSVKKDGLRVTPYDQIPIIA
GALAGTANKMLQGQAIKDGINAVGLSLADGGLCHVEELDPELGAVGKATPGDSTLLQAILATGAMPIISSIGLTAQGQMM
NVNADQAAVAVAGALDAELVLLSDVSGVLDGKGHLIATLDAKQADALIAGKVITDGMIVKVKAALEAAQDLGRPIEVATW
RYPEKLAKLFGGESIGTRFLP

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=256, Percent_Identity=57.421875, Blast_Score=270, Evalue=8e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_VIBC3 (A5F4Z5)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F4Z5
- SMR:   A5F4Z5
- STRING:   A5F4Z5
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A2219
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- ProtClustDB:   PRK00942
- BioCyc:   VCHO345073:VC0395_A2219-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 27013; Mature: 26882

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: BINDING 70-70 BINDING 162-162

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLKLSPLVIKLGGAALDCAETLSKLFGAIAQYQNQAQRRIVIVHGGGYLVDDLMAKLQ
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEHHHHHHHHH
LKSVKKDGLRVTPYDQIPIIAGALAGTANKMLQGQAIKDGINAVGLSLADGGLCHVEELD
HHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHCCHHHHHCHHHHEEEECCCCEEEHHHCC
PELGAVGKATPGDSTLLQAILATGAMPIISSIGLTAQGQMMNVNADQAAVAVAGALDAEL
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCEEECCCCHHHHHHHCCCCCEE
VLLSDVSGVLDGKGHLIATLDAKQADALIAGKVITDGMIVKVKAALEAAQDLGRPIEVAT
EEEECCCHHCCCCCCEEEEECCCCCCCEEECCEECCCEEEEHHHHHHHHHHCCCCEEEEE
WRYPEKLAKLFGGESIGTRFLP
CCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SDLKLSPLVIKLGGAALDCAETLSKLFGAIAQYQNQAQRRIVIVHGGGYLVDDLMAKLQ
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEHHHHHHHHH
LKSVKKDGLRVTPYDQIPIIAGALAGTANKMLQGQAIKDGINAVGLSLADGGLCHVEELD
HHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHCCHHHHHCHHHHEEEECCCCEEEHHHCC
PELGAVGKATPGDSTLLQAILATGAMPIISSIGLTAQGQMMNVNADQAAVAVAGALDAEL
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCEEECCCCHHHHHHHCCCCCEE
VLLSDVSGVLDGKGHLIATLDAKQADALIAGKVITDGMIVKVKAALEAAQDLGRPIEVAT
EEEECCCHHCCCCCCEEEEECCCCCCCEEECCEECCCEEEEHHHHHHHHHHCCCCEEEEE
WRYPEKLAKLFGGESIGTRFLP
CCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA