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The map label for this gene is argC [H]

Identifier: 147675531

GI number: 147675531

Start: 2369889

End: 2370929

Strand: Reverse

Name: argC [H]

Synonym: VC0395_A2220

Alternate gene names: 147675531

Gene position: 2370929-2369889 (Counterclockwise)

Preceding gene: 147673248

Following gene: 147675582

Centisome position: 78.4

GC content: 50.14

Gene sequence:

>1041_bases
TTGTTCGCTCTCTTTCACCACTTAATACGGATGTTTTTGATGTTAAAAACCACCATCATCGGCGCAAGCGGTTACACCGG
AGCAGAACTGGCTCTTATGGTGCACAAACACCCACAACTCACGCTATCAGGTTTATACGTTTCCGCCAACAGTGTGGATG
CGGGCAAATCGCTGGCGCAGTTGCATGGTCGAGTGGCAGGGCTGATTGATATGCCAGTGCAAGCCTTGACTGATGTGGAT
ACTGTTGCGGCCGAGTGTGATGTGGTCTTTCTGGCCACCGCGCATGAAGTGAGTCATGACCTCGCGCCGCAATTTCTCGC
TCAAGGTTGTCAGGTCTTTGATCTGTCTGGTGCATTTCGGGTGCAGAGCGAAGCGTTTTATCCAACCTTTTATGGCTTTG
CGCATCAGCATTCTGAATGGTTGGAAAAAGCGGTGTATGGCCTGGCTGAGTGGAATGCGGAAGCAATCAAAACCAGCCCT
ATGATTGCTGTTGCGGGTTGCTACCCAACGGCATCGCAACTGGCGATTAAGCCTCTGTTGGTGGATGGGTTAATCGACAC
TACCCAATGGCCAGTGATTAACGCGGTGAGTGGTGTCTCTGGTGCGGGGCGTAAAGCCACCATGACCAACAGCTTCTGTG
AAGTGAGCTTGCAGCCCTACGGTGTGTTTAACCACCGTCATCAACCAGAAATTGCGACTCATCTAGGCTGTGAGGTGATC
TTCACCCCGCATCTTGGCAACTTTAAGCGCGGGATTCTGGCCACCATCACAATGAAATTAGCGGATGGTGTCACCGAGCA
GCAAGTCGCAGAAGCTTTTAGCAAGGCGTATCAAGATAAGCCATTGGTGCGTTTCAGCAATGGTTTACCACGGATTCAAG
ATGTCGAGTTTACCCCATTTTGTGACCTCGGCTGGAAGGTACAAGGACGTCACATCATAGTGGTGTCTGCTATCGACAAT
TTATTGAAAGGCGCATCGAGTCAAGCGATGCAGTGTTTAAATATTCACTACGGTTTCGATGAATTAACCGCGTTGGTGTA
A

Upstream 100 bases:

>100_bases
CTATTGACAGAGTGTCGGTGAAACGGTAAAACACATATTAAATCACTTTAAGTGAATAAAAAAACAATTAATCGCAATTT
TGAAAGATGAATAGTCAGCG

Downstream 100 bases:

>100_bases
GGGTTCAACATGTCAGATCTTAAGCTCAGTCCTTTAGTGATTAAGTTAGGCGGTGCGGCGCTCGATTGCGCAGAGACACT
TAGCAAATTGTTTGGTGCGA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MFALFHHLIRMFLMLKTTIIGASGYTGAELALMVHKHPQLTLSGLYVSANSVDAGKSLAQLHGRVAGLIDMPVQALTDVD
TVAAECDVVFLATAHEVSHDLAPQFLAQGCQVFDLSGAFRVQSEAFYPTFYGFAHQHSEWLEKAVYGLAEWNAEAIKTSP
MIAVAGCYPTASQLAIKPLLVDGLIDTTQWPVINAVSGVSGAGRKATMTNSFCEVSLQPYGVFNHRHQPEIATHLGCEVI
FTPHLGNFKRGILATITMKLADGVTEQQVAEAFSKAYQDKPLVRFSNGLPRIQDVEFTPFCDLGWKVQGRHIIVVSAIDN
LLKGASSQAMQCLNIHYGFDELTALV

Sequences:

>Translated_346_residues
MFALFHHLIRMFLMLKTTIIGASGYTGAELALMVHKHPQLTLSGLYVSANSVDAGKSLAQLHGRVAGLIDMPVQALTDVD
TVAAECDVVFLATAHEVSHDLAPQFLAQGCQVFDLSGAFRVQSEAFYPTFYGFAHQHSEWLEKAVYGLAEWNAEAIKTSP
MIAVAGCYPTASQLAIKPLLVDGLIDTTQWPVINAVSGVSGAGRKATMTNSFCEVSLQPYGVFNHRHQPEIATHLGCEVI
FTPHLGNFKRGILATITMKLADGVTEQQVAEAFSKAYQDKPLVRFSNGLPRIQDVEFTPFCDLGWKVQGRHIIVVSAIDN
LLKGASSQAMQCLNIHYGFDELTALV
>Mature_346_residues
MFALFHHLIRMFLMLKTTIIGASGYTGAELALMVHKHPQLTLSGLYVSANSVDAGKSLAQLHGRVAGLIDMPVQALTDVD
TVAAECDVVFLATAHEVSHDLAPQFLAQGCQVFDLSGAFRVQSEAFYPTFYGFAHQHSEWLEKAVYGLAEWNAEAIKTSP
MIAVAGCYPTASQLAIKPLLVDGLIDTTQWPVINAVSGVSGAGRKATMTNSFCEVSLQPYGVFNHRHQPEIATHLGCEVI
FTPHLGNFKRGILATITMKLADGVTEQQVAEAFSKAYQDKPLVRFSNGLPRIQDVEFTPFCDLGWKVQGRHIIVVSAIDN
LLKGASSQAMQCLNIHYGFDELTALV

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=334, Percent_Identity=60.7784431137725, Blast_Score=423, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6320913, Length=343, Percent_Identity=29.1545189504373, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 37650; Mature: 37650

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS01224 ARGC ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFALFHHLIRMFLMLKTTIIGASGYTGAELALMVHKHPQLTLSGLYVSANSVDAGKSLAQ
CHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHH
LHGRVAGLIDMPVQALTDVDTVAAECDVVFLATAHEVSHDLAPQFLAQGCQVFDLSGAFR
HHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCCEEEECCCCEE
VQSEAFYPTFYGFAHQHSEWLEKAVYGLAEWNAEAIKTSPMIAVAGCYPTASQLAIKPLL
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCEEEEECCCCHHHHHHHHHH
VDGLIDTTQWPVINAVSGVSGAGRKATMTNSFCEVSLQPYGVFNHRHQPEIATHLGCEVI
HHCCCCCCCCCHHHHHCCCCCCCCCEEECCCEEEEEECCCEECCCCCCCCHHHHCCCEEE
FTPHLGNFKRGILATITMKLADGVTEQQVAEAFSKAYQDKPLVRFSNGLPRIQDVEFTPF
EECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCC
CDLGWKVQGRHIIVVSAIDNLLKGASSQAMQCLNIHYGFDELTALV
CCCCCEECCCEEEEEHHHHHHHCCCCHHHHHHHHEECCHHHHHHCC
>Mature Secondary Structure
MFALFHHLIRMFLMLKTTIIGASGYTGAELALMVHKHPQLTLSGLYVSANSVDAGKSLAQ
CHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHH
LHGRVAGLIDMPVQALTDVDTVAAECDVVFLATAHEVSHDLAPQFLAQGCQVFDLSGAFR
HHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCCEEEECCCCEE
VQSEAFYPTFYGFAHQHSEWLEKAVYGLAEWNAEAIKTSPMIAVAGCYPTASQLAIKPLL
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCEEEEECCCCHHHHHHHHHH
VDGLIDTTQWPVINAVSGVSGAGRKATMTNSFCEVSLQPYGVFNHRHQPEIATHLGCEVI
HHCCCCCCCCCHHHHHCCCCCCCCCEEECCCEEEEEECCCEECCCCCCCCHHHHCCCEEE
FTPHLGNFKRGILATITMKLADGVTEQQVAEAFSKAYQDKPLVRFSNGLPRIQDVEFTPF
EECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCC
CDLGWKVQGRHIIVVSAIDNLLKGASSQAMQCLNIHYGFDELTALV
CCCCCEECCCEEEEEHHHHHHHCCCCHHHHHHHHEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]