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The map label for this gene is nrdR [H]

Identifier: 146341345

GI number: 146341345

Start: 4632601

End: 4633086

Strand: Reverse

Name: nrdR [H]

Synonym: BRADO4429

Alternate gene names: 146341345

Gene position: 4633086-4632601 (Counterclockwise)

Preceding gene: 146341346

Following gene: 146341344

Centisome position: 62.13

GC content: 65.64

Gene sequence:

>486_bases
ATGCGCTGCCCGAGCTGCAACAGCCTCGATACGCAGGTGAAGGACTCCCGCCCCACCGAGGATTCCTCGGTGATCCGGCG
GCGGCGGGTCTGCGTCACCTGCAACTTCCGCTTCACGACCTTCGAGCGGGTGCAGCTGCGCGAACTCACCGTCATCAAGC
GCAACGGCCGTCGCGTGCCGTTCGACCGCGACAAGCTGATGCGCTCGGTGCAGATCTCGCTGCGCAAGCGCTCGGTCGAT
CCGGAGCGGGTCGAGAAGATGGTGTCGGCGATCGTGCGCGAGCTCGAGAGCGGCGGTGAATCAGAAGTCTCGTCGGAGGC
GATCGGCGAGATCGTGATGGAGCATCTGCGCGATCTCGACGACGTCGCCTATGTCCGCTTCGCCTCGGTTTACCGCAATT
TCCGCGAGGCCAAGGATTTCGAGGCGGTGCTCGGCGAGCTCTCGGCGGAGGACGAAACCCCGCGGCTGGCGCCGGTCCGC
AAATGA

Upstream 100 bases:

>100_bases
GGCCCTGACGGCAGCGCGCCGCTGGTCGAAGCCGCGGTCAAGGAGAAGGTGAAGGCGCTGACCGACCGGTTCCCGATCTA
TCAGTAAGGCGTAAGGCGAC

Downstream 100 bases:

>100_bases
TCTTCCGGGTGCTGGTCGATCAGGTCGGCGAGAAGCTGAAGGCGCAGAAGGACGCCGACCGCCGCTTCATGCAGTTGGCG
CTGACGCTCGGCCGTCGCGG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MRCPSCNSLDTQVKDSRPTEDSSVIRRRRVCVTCNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLMRSVQISLRKRSVD
PERVEKMVSAIVRELESGGESEVSSEAIGEIVMEHLRDLDDVAYVRFASVYRNFREAKDFEAVLGELSAEDETPRLAPVR
K

Sequences:

>Translated_161_residues
MRCPSCNSLDTQVKDSRPTEDSSVIRRRRVCVTCNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLMRSVQISLRKRSVD
PERVEKMVSAIVRELESGGESEVSSEAIGEIVMEHLRDLDDVAYVRFASVYRNFREAKDFEAVLGELSAEDETPRLAPVR
K
>Mature_161_residues
MRCPSCNSLDTQVKDSRPTEDSSVIRRRRVCVTCNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLMRSVQISLRKRSVD
PERVEKMVSAIVRELESGGESEVSSEAIGEIVMEHLRDLDDVAYVRFASVYRNFREAKDFEAVLGELSAEDETPRLAPVR
K

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=47.8571428571429, Blast_Score=127, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 18655; Mature: 18655

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPSCNSLDTQVKDSRPTEDSSVIRRRRVCVTCNFRFTTFERVQLRELTVIKRNGRRVP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCEECHHHHHHHHHHHHHHCCCCCCC
FDRDKLMRSVQISLRKRSVDPERVEKMVSAIVRELESGGESEVSSEAIGEIVMEHLRDLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DVAYVRFASVYRNFREAKDFEAVLGELSAEDETPRLAPVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRCPSCNSLDTQVKDSRPTEDSSVIRRRRVCVTCNFRFTTFERVQLRELTVIKRNGRRVP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCEECHHHHHHHHHHHHHHCCCCCCC
FDRDKLMRSVQISLRKRSVDPERVEKMVSAIVRELESGGESEVSSEAIGEIVMEHLRDLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DVAYVRFASVYRNFREAKDFEAVLGELSAEDETPRLAPVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA