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The map label for this gene is ribD [H]

Identifier: 146341344

GI number: 146341344

Start: 4631453

End: 4632604

Strand: Reverse

Name: ribD [H]

Synonym: BRADO4428

Alternate gene names: 146341344

Gene position: 4632604-4631453 (Counterclockwise)

Preceding gene: 146341345

Following gene: 146341343

Centisome position: 62.13

GC content: 70.05

Gene sequence:

>1152_bases
ATGATCTTCCGGGTGCTGGTCGATCAGGTCGGCGAGAAGCTGAAGGCGCAGAAGGACGCCGACCGCCGCTTCATGCAGTT
GGCGCTGACGCTCGGCCGTCGCGGGCAGGGGCGGACGTGGCCGAACCCGGCCGTCGGTGCCGTCGTGGTCAAGGATGGCG
TGATCGTCGGTCGCGGCTGGACCCAGCCGGGCGGCCGGCCGCATGCCGAGCCGGAGGCGCTGCGGCGCGCGGGCGAGGCG
GCCAAGGGCGCCACGCTCTATGTGACCTTGGAGCCGTGCTCGCATTTCGGCAAGTCGCCGCCCTGCGCCGACGCGGTGAT
CGCCGCCGGCATCAGCCGCGTCGTGTCGGCAGTCGAGGATCCCAATCCGGAGGTCGCGGCGCAGGGGCACGCCAAGCTCA
GGGCGGCCGGCATTCAGGTCGAGGTCGGACTGTGCTCGGCGGACGCCAAGCGCGACCATGCCGGGCATTTCCGCCGCATC
CGCGATGGGCGGCCGCAGGTGATCCTCAAGCTGGCCGTCTCGGCGGACGACAAGATCGCCGCCGCAGGCAGCAAGCCGGT
TGCGATTACCGGCGAAGCCGCGCGCACGCGCGTGCATCTGCTGCGCGCGCAGAGCGATGCGATCCTCATTGGGGTGCGCA
CCGCGATCGCCGATGATCCCTTGCTGACCTGCCGCCTGCCGGGCATGGAGCCGCGGTCGCCTGTTCGCGTCGTGCTCGAT
CCGATGCTGCGGCTTCCGTCGGCCAGCCGTCTGATACAGTCCGCGCGCACCACGCCGCTGTGGCTCGTCGCGTCCGAGGT
GGCGGAGCCTGCGACCGCGACAAGGCTAGGCGCCGCCGGTGCGCAGGTGATCCGCGTGCCGCCGCAGGCCGACCCTTCCG
CGCTCGAGCCGCCCGCCGTGCTCAAGGCTCTCGCCGAGAAGGGTATCACGCGCCTGATGATCGAAGGCGGCAGCCGCGTA
GCATCATCTTTCATGCAGAGCGGCCTCGTCGATGAGATCTGGCTGCTGCGCGGCCCCCGCGAGATCGGCGCCGATGGCAT
CGCTGCGCTGGACGCATTGCCGCTGACCGCAATCACGCAGTCGCCCGCTTATCGCGTTCGTGCTAGCGAAACGCTCGATC
CCGACATCCTTACGATTTACGAGCGCGTGTAA

Upstream 100 bases:

>100_bases
CCTCGGTTTACCGCAATTTCCGCGAGGCCAAGGATTTCGAGGCGGTGCTCGGCGAGCTCTCGGCGGAGGACGAAACCCCG
CGGCTGGCGCCGGTCCGCAA

Downstream 100 bases:

>100_bases
TGTTTACCGGCATCGTCACCGACATCGGCGAGATCGTCAGCCTGACGCCGCGGACCGAGGGCAAGCTGCACCGGCTGCGC
ATCGCCAGCGCTTACGACCA

Product: bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino) uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MIFRVLVDQVGEKLKAQKDADRRFMQLALTLGRRGQGRTWPNPAVGAVVVKDGVIVGRGWTQPGGRPHAEPEALRRAGEA
AKGATLYVTLEPCSHFGKSPPCADAVIAAGISRVVSAVEDPNPEVAAQGHAKLRAAGIQVEVGLCSADAKRDHAGHFRRI
RDGRPQVILKLAVSADDKIAAAGSKPVAITGEAARTRVHLLRAQSDAILIGVRTAIADDPLLTCRLPGMEPRSPVRVVLD
PMLRLPSASRLIQSARTTPLWLVASEVAEPATATRLGAAGAQVIRVPPQADPSALEPPAVLKALAEKGITRLMIEGGSRV
ASSFMQSGLVDEIWLLRGPREIGADGIAALDALPLTAITQSPAYRVRASETLDPDILTIYERV

Sequences:

>Translated_383_residues
MIFRVLVDQVGEKLKAQKDADRRFMQLALTLGRRGQGRTWPNPAVGAVVVKDGVIVGRGWTQPGGRPHAEPEALRRAGEA
AKGATLYVTLEPCSHFGKSPPCADAVIAAGISRVVSAVEDPNPEVAAQGHAKLRAAGIQVEVGLCSADAKRDHAGHFRRI
RDGRPQVILKLAVSADDKIAAAGSKPVAITGEAARTRVHLLRAQSDAILIGVRTAIADDPLLTCRLPGMEPRSPVRVVLD
PMLRLPSASRLIQSARTTPLWLVASEVAEPATATRLGAAGAQVIRVPPQADPSALEPPAVLKALAEKGITRLMIEGGSRV
ASSFMQSGLVDEIWLLRGPREIGADGIAALDALPLTAITQSPAYRVRASETLDPDILTIYERV
>Mature_383_residues
MIFRVLVDQVGEKLKAQKDADRRFMQLALTLGRRGQGRTWPNPAVGAVVVKDGVIVGRGWTQPGGRPHAEPEALRRAGEA
AKGATLYVTLEPCSHFGKSPPCADAVIAAGISRVVSAVEDPNPEVAAQGHAKLRAAGIQVEVGLCSADAKRDHAGHFRRI
RDGRPQVILKLAVSADDKIAAAGSKPVAITGEAARTRVHLLRAQSDAILIGVRTAIADDPLLTCRLPGMEPRSPVRVVLD
PMLRLPSASRLIQSARTTPLWLVASEVAEPATATRLGAAGAQVIRVPPQADPSALEPPAVLKALAEKGITRLMIEGGSRV
ASSFMQSGLVDEIWLLRGPREIGADGIAALDALPLTAITQSPAYRVRASETLDPDILTIYERV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=368, Percent_Identity=39.4021739130435, Blast_Score=248, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40565; Mature: 40565

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFRVLVDQVGEKLKAQKDADRRFMQLALTLGRRGQGRTWPNPAVGAVVVKDGVIVGRGW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCEEEECCC
TQPGGRPHAEPEALRRAGEAAKGATLYVTLEPCSHFGKSPPCADAVIAAGISRVVSAVED
CCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCC
PNPEVAAQGHAKLRAAGIQVEVGLCSADAKRDHAGHFRRIRDGRPQVILKLAVSADDKIA
CCCCCCCCCCCEEEEECEEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCEE
AAGSKPVAITGEAARTRVHLLRAQSDAILIGVRTAIADDPLLTCRLPGMEPRSPVRVVLD
ECCCCCEEEECHHHHHHHHHEECCCCEEEEEEEHHHCCCCEEEEECCCCCCCCCHHHHHH
PMLRLPSASRLIQSARTTPLWLVASEVAEPATATRLGAAGAQVIRVPPQADPSALEPPAV
HHHHCCCHHHHHHHCCCCEEEEEEHHHCCCHHHHHHCCCCCEEEECCCCCCCCCCCCHHH
LKALAEKGITRLMIEGGSRVASSFMQSGLVDEIWLLRGPREIGADGIAALDALPLTAITQ
HHHHHHCCCEEEEECCCHHHHHHHHHCCCHHHHHHHCCCHHHCCCHHHHHHCCCHHHCCC
SPAYRVRASETLDPDILTIYERV
CCCEEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MIFRVLVDQVGEKLKAQKDADRRFMQLALTLGRRGQGRTWPNPAVGAVVVKDGVIVGRGW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCEEEECCC
TQPGGRPHAEPEALRRAGEAAKGATLYVTLEPCSHFGKSPPCADAVIAAGISRVVSAVED
CCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCC
PNPEVAAQGHAKLRAAGIQVEVGLCSADAKRDHAGHFRRIRDGRPQVILKLAVSADDKIA
CCCCCCCCCCCEEEEECEEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCEE
AAGSKPVAITGEAARTRVHLLRAQSDAILIGVRTAIADDPLLTCRLPGMEPRSPVRVVLD
ECCCCCEEEECHHHHHHHHHEECCCCEEEEEEEHHHCCCCEEEEECCCCCCCCCHHHHHH
PMLRLPSASRLIQSARTTPLWLVASEVAEPATATRLGAAGAQVIRVPPQADPSALEPPAV
HHHHCCCHHHHHHHCCCCEEEEEEHHHCCCHHHHHHCCCCCEEEECCCCCCCCCCCCHHH
LKALAEKGITRLMIEGGSRVASSFMQSGLVDEIWLLRGPREIGADGIAALDALPLTAITQ
HHHHHHCCCEEEEECCCHHHHHHHHHCCCHHHHHHHCCCHHHCCCHHHHHHCCCHHHCCC
SPAYRVRASETLDPDILTIYERV
CCCEEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]