| Definition | Bradyrhizobium sp. ORS278 chromosome, complete genome. |
|---|---|
| Accession | NC_009445 |
| Length | 7,456,587 |
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The map label for this gene is fabG [C]
Identifier: 146338090
GI number: 146338090
Start: 1048062
End: 1048835
Strand: Direct
Name: fabG [C]
Synonym: BRADO0986
Alternate gene names: 146338090
Gene position: 1048062-1048835 (Clockwise)
Preceding gene: 146338089
Following gene: 146338091
Centisome position: 14.06
GC content: 68.22
Gene sequence:
>774_bases ATGACCCCCAACCCCTTCAATCTCGCCGGCCAGGTCGCCGTGATCACCGGCTCCAGCCGCGGCATCGGCCGGGCGTCGGC GGAGTTGCTCGCGCAACTCGGCGCCAAGGTCGTGATCTCCAGCCGCAAGGTCGACGTCTGCGAGGAGGTCGCCGCCGGCA TACGCGCCAATGGCGGCGACGCCCATGTCATCCCCTGCAACATCTCGCGCCGGTCCGAGGTCGACGCGCTGATCGACGGC GCGGTGAAGCACTACGGCCAGGTCGACATCCTCGTCTGCAACGCCGCGGTGAACCCTTACTATGGTCCGCTGCTCGACAT CACCGACGAGGCCTTCGACAAGATCATGGCCTCCAACGTGAAGAGCAACCTGTGGCTCTGCGCCAAGGCGATCCCGCCGA TGGCCGCGCGCGGCAAAGGCTCGGTCGTCATCGTCTCCTCGATCGGCGGCCTGCGCGGCTCCACCGTGATCGGCGCCTAT GGCATTTCCAAAGCAGCCGACTTTTCGCTGTGCCGCAGCCTCGCCGGCGAATGGGGCCCGCAAGGCGTGCGCGTCAACTG CGTCGCGCCCGGCCTGGTCAAGACCGACTTCGCCCGCGCGCTGTGGGAGGACGAAGCCCGCCTGAAGCAGCGCTGCGCAA CGACACCGCTCCGCCGCATCGGCGAACCGCACGAGATCGCCGGCGCGGTGGCGTATCTGGCGTCGGATGCGTCCACCTTC ATGACGGGCCAGACGATCGTGGTCGATGGCGGTGTGACGACGGCGGCGGTGTAG
Upstream 100 bases:
>100_bases CGGATGAGCGCAGCGATATCCGGGTTCATCGCCAGAGCTCGTGAGACCCCGGATGTCGCTACGCTCATCCGGGCTACGTT GTCGGTGCGGAGCAATCATC
Downstream 100 bases:
>100_bases TCTCTCTCCGCACGACGGCTGCACCCTCTCCCCTTGTGGGAGAGGGTGGCTTCGATGCAAAGCATCGAAGCCGGGTGAGG GGTCTCTTTCCTCATACTCA
Product: SDR family dehydrogenase/reductase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 257; Mature: 256
Protein sequence:
>257_residues MTPNPFNLAGQVAVITGSSRGIGRASAELLAQLGAKVVISSRKVDVCEEVAAGIRANGGDAHVIPCNISRRSEVDALIDG AVKHYGQVDILVCNAAVNPYYGPLLDITDEAFDKIMASNVKSNLWLCAKAIPPMAARGKGSVVIVSSIGGLRGSTVIGAY GISKAADFSLCRSLAGEWGPQGVRVNCVAPGLVKTDFARALWEDEARLKQRCATTPLRRIGEPHEIAGAVAYLASDASTF MTGQTIVVDGGVTTAAV
Sequences:
>Translated_257_residues MTPNPFNLAGQVAVITGSSRGIGRASAELLAQLGAKVVISSRKVDVCEEVAAGIRANGGDAHVIPCNISRRSEVDALIDG AVKHYGQVDILVCNAAVNPYYGPLLDITDEAFDKIMASNVKSNLWLCAKAIPPMAARGKGSVVIVSSIGGLRGSTVIGAY GISKAADFSLCRSLAGEWGPQGVRVNCVAPGLVKTDFARALWEDEARLKQRCATTPLRRIGEPHEIAGAVAYLASDASTF MTGQTIVVDGGVTTAAV >Mature_256_residues TPNPFNLAGQVAVITGSSRGIGRASAELLAQLGAKVVISSRKVDVCEEVAAGIRANGGDAHVIPCNISRRSEVDALIDGA VKHYGQVDILVCNAAVNPYYGPLLDITDEAFDKIMASNVKSNLWLCAKAIPPMAARGKGSVVIVSSIGGLRGSTVIGAYG ISKAADFSLCRSLAGEWGPQGVRVNCVAPGLVKTDFARALWEDEARLKQRCATTPLRRIGEPHEIAGAVAYLASDASTFM TGQTIVVDGGVTTAAV
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=43.0327868852459, Blast_Score=204, Evalue=6e-53, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=40.2439024390244, Blast_Score=175, Evalue=4e-44, Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=34.8178137651822, Blast_Score=158, Evalue=4e-39, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=42.2680412371134, Blast_Score=148, Evalue=5e-36, Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=33.0739299610895, Blast_Score=135, Evalue=3e-32, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=41.4364640883978, Blast_Score=134, Evalue=6e-32, Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=33.4710743801653, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=33.4661354581673, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=33.2, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI302344755, Length=108, Percent_Identity=47.2222222222222, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI4503301, Length=254, Percent_Identity=29.9212598425197, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=28.8888888888889, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI210032110, Length=203, Percent_Identity=30.5418719211823, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI40807363, Length=200, Percent_Identity=32, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=29.3650793650794, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI142976729, Length=196, Percent_Identity=29.0816326530612, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=26.4822134387352, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI209862901, Length=216, Percent_Identity=31.9444444444444, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI19923983, Length=216, Percent_Identity=31.9444444444444, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI310128830, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI310115468, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI32455239, Length=222, Percent_Identity=28.8288288288288, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI5031765, Length=222, Percent_Identity=28.8288288288288, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI20149619, Length=230, Percent_Identity=27.3913043478261, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=28.8065843621399, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI7705855, Length=195, Percent_Identity=29.7435897435897, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI31542939, Length=207, Percent_Identity=28.0193236714976, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=27.5510204081633, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI25282469, Length=225, Percent_Identity=27.1111111111111, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI223718074, Length=196, Percent_Identity=31.1224489795918, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4503817, Length=195, Percent_Identity=29.2307692307692, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI4504505, Length=201, Percent_Identity=26.865671641791, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=34.4, Blast_Score=140, Evalue=7e-35, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=33.0677290836653, Blast_Score=140, Evalue=1e-34, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=34.5098039215686, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=34.8178137651822, Blast_Score=124, Evalue=4e-30, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=31.496062992126, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=33.469387755102, Blast_Score=117, Evalue=7e-28, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=33.1983805668016, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=28.4552845528455, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=30.5220883534137, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=30.327868852459, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=29.6577946768061, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1787545, Length=262, Percent_Identity=26.7175572519084, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=26.6393442622951, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786701, Length=189, Percent_Identity=31.2169312169312, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=25.8823529411765, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=39.8406374501992, Blast_Score=197, Evalue=5e-51, Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=34.6303501945525, Blast_Score=155, Evalue=2e-38, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=38.1679389312977, Blast_Score=141, Evalue=4e-34, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=36.8421052631579, Blast_Score=137, Evalue=6e-33, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=36.6935483870968, Blast_Score=134, Evalue=3e-32, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=38.6973180076628, Blast_Score=134, Evalue=3e-32, Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=37.4517374517375, Blast_Score=127, Evalue=4e-30, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=35.1145038167939, Blast_Score=123, Evalue=7e-29, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=34.0996168582375, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=32.962962962963, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=35.2490421455939, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=34.7490347490347, Blast_Score=120, Evalue=9e-28, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=35.4961832061069, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=34.7490347490347, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=32.8301886792453, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=33.976833976834, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=31.4176245210728, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=33.2046332046332, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=31.6602316602317, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=31.6602316602317, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=29.5546558704453, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=32.4, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI115534694, Length=259, Percent_Identity=30.8880308880309, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=32.8185328185328, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=30.6772908366534, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17561272, Length=256, Percent_Identity=31.640625, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=32.0754716981132, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=30.1526717557252, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=29.2, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=28.8973384030418, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17555612, Length=264, Percent_Identity=31.8181818181818, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71997099, Length=262, Percent_Identity=30.1526717557252, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=30.1587301587302, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17567345, Length=217, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=26.5625, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17568967, Length=237, Percent_Identity=27.0042194092827, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=28.125, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=28.2722513089005, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=30.3149606299213, Blast_Score=106, Evalue=3e-24, Organism=Saccharomyces cerevisiae, GI6323882, Length=250, Percent_Identity=26.8, Blast_Score=76, Evalue=4e-15, Organism=Saccharomyces cerevisiae, GI6322226, Length=196, Percent_Identity=32.1428571428571, Blast_Score=70, Evalue=4e-13, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=39.4308943089431, Blast_Score=190, Evalue=8e-49, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=36.9918699186992, Blast_Score=145, Evalue=2e-35, Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=37.5, Blast_Score=140, Evalue=9e-34, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=34.8, Blast_Score=139, Evalue=2e-33, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=34.2629482071713, Blast_Score=130, Evalue=1e-30, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=37.0517928286853, Blast_Score=124, Evalue=6e-29, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=31.7269076305221, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI24640492, Length=197, Percent_Identity=28.9340101522843, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI281364892, Length=202, Percent_Identity=29.7029702970297, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=27.6381909547739, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=26.5873015873016, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=29.6482412060301, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=30.4568527918782, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI28571387, Length=198, Percent_Identity=28.2828282828283, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 26693; Mature: 26562
Theoretical pI: Translated: 8.04; Mature: 8.04
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.7 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 2.7 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTPNPFNLAGQVAVITGSSRGIGRASAELLAQLGAKVVISSRKVDVCEEVAAGIRANGGD CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCC AHVIPCNISRRSEVDALIDGAVKHYGQVDILVCNAAVNPYYGPLLDITDEAFDKIMASNV EEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCC KSNLWLCAKAIPPMAARGKGSVVIVSSIGGLRGSTVIGAYGISKAADFSLCRSLAGEWGP CCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCC QGVRVNCVAPGLVKTDFARALWEDEARLKQRCATTPLRRIGEPHEIAGAVAYLASDASTF CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCHHE MTGQTIVVDGGVTTAAV ECCCEEEEECCCCCCCC >Mature Secondary Structure TPNPFNLAGQVAVITGSSRGIGRASAELLAQLGAKVVISSRKVDVCEEVAAGIRANGGD CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCC AHVIPCNISRRSEVDALIDGAVKHYGQVDILVCNAAVNPYYGPLLDITDEAFDKIMASNV EEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCC KSNLWLCAKAIPPMAARGKGSVVIVSSIGGLRGSTVIGAYGISKAADFSLCRSLAGEWGP CCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCC QGVRVNCVAPGLVKTDFARALWEDEARLKQRCATTPLRRIGEPHEIAGAVAYLASDASTF CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCHHE MTGQTIVVDGGVTTAAV ECCCEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]