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The map label for this gene is yafC [C]

Identifier: 146337973

GI number: 146337973

Start: 917544

End: 918437

Strand: Direct

Name: yafC [C]

Synonym: BRADO0865

Alternate gene names: 146337973

Gene position: 917544-918437 (Clockwise)

Preceding gene: 146337969

Following gene: 146337974

Centisome position: 12.31

GC content: 66.67

Gene sequence:

>894_bases
ATGGACAAGCTCAGCAGCCTCAGGGCTTTCGTGAAGGTGGTCGAGAGCGGCAGCTTCGCCGAAGCGGGTCGTCAGCTGCG
GCTGTCGCGCTCGGCGATCTCGAAATATATCGGCGAGCTCGAGCAGAGCCTCGGCGTGCAGCTGATCGTCCGGACCACCC
GCCACGCCAGCCCGACCGAGACCGGCCAGCGCTATTTCGAGCGCGCCGTCGCGATTCTTGCCGAGCTCGATGCCGCTGAC
CAGGCCGTCAGCCAGTCGCAGGCCGCACCGCGCGGGCTGTTGCGCGTCAATGCCCCGATGTCGTTCGGCACGATGCGGCT
CGGGCCGGTCGTGGCCGACTTCATGGTCCGCTTTCCCGAGCTGCAGTTGCAGATCGTGTTGAGCGACGACCTGCTCGATC
CGGTGCAGGACGGCTTCGACGTGACATTGCGGATCGCCGAGCTGGAATCGTCGAGCCTGGTGGCGCGCCGGATCACGCCG
GTGGACCGGGTTATCTGCGCCGCGCCCGCTTATCTGGCCCGGCATGGCACGCCCGAGAGTCCGGAAGAGCTGCGCCGCCA
TTCCTCCCTGACCTACGGCTTTCTGCTGACCGGCAACCAATGGAAGCTCACCGGCCGGGACGGCAATCACTGGATCCAGC
CGGCCTGGAGCCTGTGCGTCAACAACGCCGAGGTGCTGCGCGACGTCGCCATCAAGGGGCAGGGGATTGCGCTGATCCCG
CGCTTCATCGCCGCGGATGCGCTCGCCAGCGGCGCGCTCACCGCAATCCTCTCCGACTACACCGCGCCCCCATTGGCGCT
CTACGCCATCTATCCGCCGACGCGGCACCTCTCGGTGAAGGTACGATTGTTCATCGACTTTCTGGTCGAGCGCTTCGGCA
AGGGGTCGGGTTGA

Upstream 100 bases:

>100_bases
CGAATGTCTGAACGCAATATTGGCCGGCTTTGATCTGGAGACAATCCGTGCTCTTGTGACGTGTCTGTCTACGATTTGGC
GACAATGGCGCCTGGAGACC

Downstream 100 bases:

>100_bases
CCAGTCAGTGGGCCCCGGGTGAGGCGCAAATCGCCTCGAACCTTTAACCGCGCGCTGATAGTGTCGACGGGTCAGGAGAA
AGGACGGACGTATGGGGCGG

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MDKLSSLRAFVKVVESGSFAEAGRQLRLSRSAISKYIGELEQSLGVQLIVRTTRHASPTETGQRYFERAVAILAELDAAD
QAVSQSQAAPRGLLRVNAPMSFGTMRLGPVVADFMVRFPELQLQIVLSDDLLDPVQDGFDVTLRIAELESSSLVARRITP
VDRVICAAPAYLARHGTPESPEELRRHSSLTYGFLLTGNQWKLTGRDGNHWIQPAWSLCVNNAEVLRDVAIKGQGIALIP
RFIAADALASGALTAILSDYTAPPLALYAIYPPTRHLSVKVRLFIDFLVERFGKGSG

Sequences:

>Translated_297_residues
MDKLSSLRAFVKVVESGSFAEAGRQLRLSRSAISKYIGELEQSLGVQLIVRTTRHASPTETGQRYFERAVAILAELDAAD
QAVSQSQAAPRGLLRVNAPMSFGTMRLGPVVADFMVRFPELQLQIVLSDDLLDPVQDGFDVTLRIAELESSSLVARRITP
VDRVICAAPAYLARHGTPESPEELRRHSSLTYGFLLTGNQWKLTGRDGNHWIQPAWSLCVNNAEVLRDVAIKGQGIALIP
RFIAADALASGALTAILSDYTAPPLALYAIYPPTRHLSVKVRLFIDFLVERFGKGSG
>Mature_297_residues
MDKLSSLRAFVKVVESGSFAEAGRQLRLSRSAISKYIGELEQSLGVQLIVRTTRHASPTETGQRYFERAVAILAELDAAD
QAVSQSQAAPRGLLRVNAPMSFGTMRLGPVVADFMVRFPELQLQIVLSDDLLDPVQDGFDVTLRIAELESSSLVARRITP
VDRVICAAPAYLARHGTPESPEELRRHSSLTYGFLLTGNQWKLTGRDGNHWIQPAWSLCVNNAEVLRDVAIKGQGIALIP
RFIAADALASGALTAILSDYTAPPLALYAIYPPTRHLSVKVRLFIDFLVERFGKGSG

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=36.1774744027304, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=33.448275862069, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=31.5254237288136, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=31.740614334471, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=31.5254237288136, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=28.6206896551724, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787128, Length=294, Percent_Identity=27.2108843537415, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788706, Length=304, Percent_Identity=26.6447368421053, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=149, Percent_Identity=35.5704697986577, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788481, Length=300, Percent_Identity=26, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786448, Length=305, Percent_Identity=26.2295081967213, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789173, Length=273, Percent_Identity=26.3736263736264, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=124, Percent_Identity=32.258064516129, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788297, Length=134, Percent_Identity=29.8507462686567, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32498; Mature: 32498

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLSSLRAFVKVVESGSFAEAGRQLRLSRSAISKYIGELEQSLGVQLIVRTTRHASPTE
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCH
TGQRYFERAVAILAELDAADQAVSQSQAAPRGLLRVNAPMSFGTMRLGPVVADFMVRFPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
LQLQIVLSDDLLDPVQDGFDVTLRIAELESSSLVARRITPVDRVICAAPAYLARHGTPES
EEEEEEECCCCCCHHHCCCEEEEEEEECCCCHHHHHHCCHHHHHHHHCHHHHHHCCCCCC
PEELRRHSSLTYGFLLTGNQWKLTGRDGNHWIQPAWSLCVNNAEVLRDVAIKGQGIALIP
HHHHHHHCCCEEEEEEECCEEEEECCCCCCHHCHHHHHHCCCHHHHHHHHHCCCCHHHHH
RFIAADALASGALTAILSDYTAPPLALYAIYPPTRHLSVKVRLFIDFLVERFGKGSG
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDKLSSLRAFVKVVESGSFAEAGRQLRLSRSAISKYIGELEQSLGVQLIVRTTRHASPTE
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCH
TGQRYFERAVAILAELDAADQAVSQSQAAPRGLLRVNAPMSFGTMRLGPVVADFMVRFPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
LQLQIVLSDDLLDPVQDGFDVTLRIAELESSSLVARRITPVDRVICAAPAYLARHGTPES
EEEEEEECCCCCCHHHCCCEEEEEEEECCCCHHHHHHCCHHHHHHHHCHHHHHHCCCCCC
PEELRRHSSLTYGFLLTGNQWKLTGRDGNHWIQPAWSLCVNNAEVLRDVAIKGQGIALIP
HHHHHHHCCCEEEEEEECCEEEEECCCCCCHHCHHHHHHCCCHHHHHHHHHCCCCHHHHH
RFIAADALASGALTAILSDYTAPPLALYAIYPPTRHLSVKVRLFIDFLVERFGKGSG
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]