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The map label for this gene is yedX [C]

Identifier: 146337974

GI number: 146337974

Start: 918529

End: 918885

Strand: Direct

Name: yedX [C]

Synonym: BRADO0866

Alternate gene names: 146337974

Gene position: 918529-918885 (Clockwise)

Preceding gene: 146337973

Following gene: 146337975

Centisome position: 12.32

GC content: 63.87

Gene sequence:

>357_bases
ATGGGGCGGTTGAGTACGCATATTCTGGATACGGTCAGGGGCAAGCCGGCCGTCGATGTCGCGATTGATCTCGACATGCT
CCAGCCGGACGGCTCCTGGCACCGGATCAAGCAGGTCCTGACCAACGCCGATGGACGCACCGACCAGCCGCTGCTGGCAG
GCGACGAGTTTACCACCGGCACCTACATGCTCACGTTCCATATGGGCGCATACTTCAAGGCCCACGGCCTCGCCTCCGGC
GATCCGCTGTTCCTCGACCTGATCCCGCTCCGCTTTGCGGTCGCCGATGCCGGCGCGCATTATCACGTGCCGCTGCTCGC
GACGCCCTGGAGCTATCAGACCTATCGCGGGAGTTGA

Upstream 100 bases:

>100_bases
TCGGGTTGACCAGTCAGTGGGCCCCGGGTGAGGCGCAAATCGCCTCGAACCTTTAACCGCGCGCTGATAGTGTCGACGGG
TCAGGAGAAAGGACGGACGT

Downstream 100 bases:

>100_bases
GTGAGATGAGCGCTGACGTTTACCCGCGCGACATGGTCGGTTACGGCCGCACGCCGCCGCATCCGCGCTGGCCAGGCGAC
GCCCGCATCGCCGTGCAGTT

Product: putative transthyretin-like protein

Products: NA

Alternate protein names: HIU hydrolase; HIUHase [H]

Number of amino acids: Translated: 118; Mature: 117

Protein sequence:

>118_residues
MGRLSTHILDTVRGKPAVDVAIDLDMLQPDGSWHRIKQVLTNADGRTDQPLLAGDEFTTGTYMLTFHMGAYFKAHGLASG
DPLFLDLIPLRFAVADAGAHYHVPLLATPWSYQTYRGS

Sequences:

>Translated_118_residues
MGRLSTHILDTVRGKPAVDVAIDLDMLQPDGSWHRIKQVLTNADGRTDQPLLAGDEFTTGTYMLTFHMGAYFKAHGLASG
DPLFLDLIPLRFAVADAGAHYHVPLLATPWSYQTYRGS
>Mature_117_residues
GRLSTHILDTVRGKPAVDVAIDLDMLQPDGSWHRIKQVLTNADGRTDQPLLAGDEFTTGTYMLTFHMGAYFKAHGLASGD
PLFLDLIPLRFAVADAGAHYHVPLLATPWSYQTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=115, Percent_Identity=40.8695652173913, Blast_Score=84, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115532922, Length=117, Percent_Identity=38.4615384615385, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115532920, Length=119, Percent_Identity=37.8151260504202, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534555, Length=119, Percent_Identity=35.2941176470588, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24652571, Length=116, Percent_Identity=38.7931034482759, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 12985; Mature: 12854

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00768 TRANSTHYRETIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLSTHILDTVRGKPAVDVAIDLDMLQPDGSWHRIKQVLTNADGRTDQPLLAGDEFTTG
CCCCHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCEECCCCCCCC
TYMLTFHMGAYFKAHGLASGDPLFLDLIPLRFAVADAGAHYHVPLLATPWSYQTYRGS
EEEEEEECCCEEEECCCCCCCCEEEEEEHHEEEEECCCCEEEEEEEECCCCCEEECCC
>Mature Secondary Structure 
GRLSTHILDTVRGKPAVDVAIDLDMLQPDGSWHRIKQVLTNADGRTDQPLLAGDEFTTG
CCCHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCEECCCCCCCC
TYMLTFHMGAYFKAHGLASGDPLFLDLIPLRFAVADAGAHYHVPLLATPWSYQTYRGS
EEEEEEECCCEEEECCCCCCCCEEEEEEHHEEEEECCCCEEEEEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]