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The map label for this gene is fmt [H]

Identifier: 146337886

GI number: 146337886

Start: 815861

End: 816796

Strand: Direct

Name: fmt [H]

Synonym: BRADO0771

Alternate gene names: 146337886

Gene position: 815861-816796 (Clockwise)

Preceding gene: 146337885

Following gene: 146337887

Centisome position: 10.94

GC content: 69.34

Gene sequence:

>936_bases
ATGCCGCTTCGCCTGATCTTCATGGGCACGCCGGACTTCGCCGTGCCGACCCTGCTCGAGCTCGCCGGCCACGGCCACGA
GATCGTGGCCGTCTACACCCGCGCGCCGAAACCCGGAGGCCGCCGCGGTCTCGCGCTGGTGCCGACCCCGATCGAGTCCG
AGGCGCGCCGGCTCGGCATTCCCGTGCTCACGCCGAAGACGCTGAAGACCGAGGAGGCCTTGGCCGAATTCCGCGCGCAT
GAGGCCGATGCCGCGGTGGTCGTCGCCTATGGCATGATCCTGCCGCAGGCGATTCTCGATGCGCCGAAGCTCGGCTGCTA
CAACCTGCATGCCTCGCTGCTGCCGCGCTGGCGCGGTGCCGCGCCGATCAACCGCGCGATCATGGCAGGTGACGCCGAGA
GCGGCGTCATGGTCATGAAGATGGATGTCGGGCTCGACACCGGCGACGTCGCGATGGCCGAACTCCTCGCCATCACCGAC
GCGATGACCGCATCCGATCTGCACGACAAGCTGTCCCGCATCGGCGCGGACCTGATGGTTCGCGCGATGGCGGCGCTGGA
GCGCGGCGGACTGACATTGACCAAGCAGGCCGAGGACGGCGTGACTTACGCCGCCAAGATCGAGAAGGCGGAGGCGCGGA
TCGACTGGACGAAGCCCGCGCATGCTGTGCTGCGCCACATCCACGGCCTGTCGCCGTTTCCCGGCGCCTGGAGCGAGATC
ACGATCGACGGCGAGGCGGTGCGGCTGAAGATCCTGCGATGCGCCCTCGCTCGCGGCACGGGCGAGCCGGGTACCGTTGT
CGACGACGAGCTCACCATCGCTTGTGCCGACAGCGCGATCCGCATCACCGAGCTGCAGCGCGCCGGCAAGAGCCCGATGA
AGGCCGCGGACTTCCTGCGCGGCACCCGCGTTGCGCCGGGCCTGCGCTTCGGTTGA

Upstream 100 bases:

>100_bases
GCATCCACGTCTCTCCATCCGGCACTGCCGCGAGACGTGGATGGCCGGGACAAGCCCGGCCATGACGGCGGGGTAGAGGC
TTTGCAGGGTCTCCGACCAC

Downstream 100 bases:

>100_bases
CCACCACAGCTCGTCAGCCGCGGGCTTGACCCGCGCATCCATCTCGCGAACAAGCTTCATGCTTGGATGGATTGCCGGGT
CGAGCCCGGCAATGACGGCC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MPLRLIFMGTPDFAVPTLLELAGHGHEIVAVYTRAPKPGGRRGLALVPTPIESEARRLGIPVLTPKTLKTEEALAEFRAH
EADAAVVVAYGMILPQAILDAPKLGCYNLHASLLPRWRGAAPINRAIMAGDAESGVMVMKMDVGLDTGDVAMAELLAITD
AMTASDLHDKLSRIGADLMVRAMAALERGGLTLTKQAEDGVTYAAKIEKAEARIDWTKPAHAVLRHIHGLSPFPGAWSEI
TIDGEAVRLKILRCALARGTGEPGTVVDDELTIACADSAIRITELQRAGKSPMKAADFLRGTRVAPGLRFG

Sequences:

>Translated_311_residues
MPLRLIFMGTPDFAVPTLLELAGHGHEIVAVYTRAPKPGGRRGLALVPTPIESEARRLGIPVLTPKTLKTEEALAEFRAH
EADAAVVVAYGMILPQAILDAPKLGCYNLHASLLPRWRGAAPINRAIMAGDAESGVMVMKMDVGLDTGDVAMAELLAITD
AMTASDLHDKLSRIGADLMVRAMAALERGGLTLTKQAEDGVTYAAKIEKAEARIDWTKPAHAVLRHIHGLSPFPGAWSEI
TIDGEAVRLKILRCALARGTGEPGTVVDDELTIACADSAIRITELQRAGKSPMKAADFLRGTRVAPGLRFG
>Mature_310_residues
PLRLIFMGTPDFAVPTLLELAGHGHEIVAVYTRAPKPGGRRGLALVPTPIESEARRLGIPVLTPKTLKTEEALAEFRAHE
ADAAVVVAYGMILPQAILDAPKLGCYNLHASLLPRWRGAAPINRAIMAGDAESGVMVMKMDVGLDTGDVAMAELLAITDA
MTASDLHDKLSRIGADLMVRAMAALERGGLTLTKQAEDGVTYAAKIEKAEARIDWTKPAHAVLRHIHGLSPFPGAWSEIT
IDGEAVRLKILRCALARGTGEPGTVVDDELTIACADSAIRITELQRAGKSPMKAADFLRGTRVAPGLRFG

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=243, Percent_Identity=31.2757201646091, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI238814322, Length=314, Percent_Identity=29.6178343949045, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI164663775, Length=323, Percent_Identity=27.2445820433437, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1789683, Length=313, Percent_Identity=42.1725239616613, Blast_Score=237, Evalue=7e-64,
Organism=Escherichia coli, GI1788589, Length=289, Percent_Identity=26.2975778546713, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI133930964, Length=261, Percent_Identity=30.2681992337165, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319458, Length=361, Percent_Identity=25.7617728531856, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45550868, Length=320, Percent_Identity=30, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI28571984, Length=234, Percent_Identity=33.7606837606838, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24585660, Length=244, Percent_Identity=26.2295081967213, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 33144; Mature: 33013

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRLIFMGTPDFAVPTLLELAGHGHEIVAVYTRAPKPGGRRGLALVPTPIESEARRLGI
CCEEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCHHHHHHCCC
PVLTPKTLKTEEALAEFRAHEADAAVVVAYGMILPQAILDAPKLGCYNLHASLLPRWRGA
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECHHHHCCCCCCC
APINRAIMAGDAESGVMVMKMDVGLDTGDVAMAELLAITDAMTASDLHDKLSRIGADLMV
CCCCCEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAMAALERGGLTLTKQAEDGVTYAAKIEKAEARIDWTKPAHAVLRHIHGLSPFPGAWSEI
HHHHHHHHCCEEEEECCCCCCEEEEEEHHHHHEECCCCHHHHHHHHHCCCCCCCCCCCEE
TIDGEAVRLKILRCALARGTGEPGTVVDDELTIACADSAIRITELQRAGKSPMKAADFLR
EECCHHHHHHHHHHHHHCCCCCCCCEECCCEEEEECCCCCHHHHHHHCCCCCHHHHHHHH
GTRVAPGLRFG
CCCCCCCCCCC
>Mature Secondary Structure 
PLRLIFMGTPDFAVPTLLELAGHGHEIVAVYTRAPKPGGRRGLALVPTPIESEARRLGI
CEEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCHHHHHHCCC
PVLTPKTLKTEEALAEFRAHEADAAVVVAYGMILPQAILDAPKLGCYNLHASLLPRWRGA
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECHHHHCCCCCCC
APINRAIMAGDAESGVMVMKMDVGLDTGDVAMAELLAITDAMTASDLHDKLSRIGADLMV
CCCCCEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAMAALERGGLTLTKQAEDGVTYAAKIEKAEARIDWTKPAHAVLRHIHGLSPFPGAWSEI
HHHHHHHHCCEEEEECCCCCCEEEEEEHHHHHEECCCCHHHHHHHHHCCCCCCCCCCCEE
TIDGEAVRLKILRCALARGTGEPGTVVDDELTIACADSAIRITELQRAGKSPMKAADFLR
EECCHHHHHHHHHHHHHCCCCCCCCEECCCEEEEECCCCCHHHHHHHCCCCCHHHHHHHH
GTRVAPGLRFG
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA