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The map label for this gene is ydeN [H]

Identifier: 146302377

GI number: 146302377

Start: 5623339

End: 5624958

Strand: Direct

Name: ydeN [H]

Synonym: Fjoh_4650

Alternate gene names: 146302377

Gene position: 5623339-5624958 (Clockwise)

Preceding gene: 146302376

Following gene: 146302378

Centisome position: 92.23

GC content: 38.27

Gene sequence:

>1620_bases
ATGGCAGTCTATAAAAAAATAACCAAAATTGTAATATCCATTTTAATAGTGCTTCTTATTCTGGCAGCATTTTTATTCTG
GCCCATTAATACCGATGGAACGTTAATACAACCCGACCAAAAATTAGCCGAAGGAAAAGCAGCATTTCTTTCCCAGAAAG
ATACTTCTGCAGCTTCAGAAAAAAAGCCCAACATTATCATTCTCCTTGCCGATGATTTAGGCAAATATGATATTTCTTTA
TACGGGGGAAAATCAACGCCAACGCCACAAATTGATTCACTTGCTGCATCTGGCGTAACTTTTACAGACGGCTATGTTTC
GTCTTCTATTTGTTCGCCTTCACGCGCAGGATTGTTAACCGGCCGTTATCAGGAACGTTTCGGACATGAATATCAGCCCG
GAGACCGATATCCTAAAAACAACTTAGAATATTATGCTTTTAAGTATCTTCTCAATACAAACAGCTGGCGTTTAAATCCA
AAAATTGAATATCCAAACGATGCCTCAATCGCTACTCAGGGACTTCCAAAATCTGAAATTACTTTTGCTGATTTAGCCAA
AAAACAAGGTTATAGTACCGCCATTATCGGAAAATGGCATTTGGGACATACCAAAGGATTTTTTCCTTTAGACCGAGGCT
TCGATTATCATTACGGCTTTTATCAGGCATTTTCACTTTTTGCGCCGGAAGATAATAATCCTGATATTATCAACCATCAC
CATACCGATTTTACCGATAAAACAATTTGGGGCAATGGCCGTGTAGGAACTGGACAAATCCGCCGAGACAGCACCATTAT
TGACGAAAAGAAATACCTGACTGAAAAATTTGCAGAAGAAGCCGAAGCTTTTATCGATAAAAACAAAAACAAACCGTTTT
TGCTTTACGTTCCGTTTAATGCGCCGCACACGCCGTTTCAGGTTCGCAAAAAATATTACGATCGTTTCCCGAATGTAAAA
GACGAAAACAAACGGGTTTATTTTGCCATGATCAGCGCACTTGATGACGCTATTGGACTAATAAGAGCCAAAGTTAAAAA
AGAAGGTCTGGAAGAAAACACCTTAATTTTCTTCGCCAGCGACAACGGCGGTGCCGATTATACTTATGCGACAACAAACG
CACCATTAAAAGGAGGCAAATTTTCTCATTTTGAAGGCGGTGTAAATGTTCCGTTTGCACTTTCGTGGAAAGGAAAAATC
AAACCGCATACTATTTATAAAACACCTGTAAGTTCACTGGATATTTTCAGCACTATTGCAGCCGTTACACATTCAGGTTT
GCCAAAAGACCGAGTTTACGACGGAGTCGATTTAGTAGATGTGGTCAATAACAATAAACAAGCACATCAAAATTTATACT
GGCGTTCCGGCGATGCAAAAGCTATTAGAAGCGGTGACTGGAAATTAATCATCAGCGGTAAAACCCATGAAACCTGGTTA
TACAATTTAGCCAAAGACAAATCTGAAACTACGGATCTGGCTTCAAAAAATCCTGAAAAAGTAAAAGAATTACAAACTGC
TTTACAAAACTGGGAAAAAGGATTAATTAAACCTTTATGGCCAAATCTAACTTATTACGAATTCGATTTTGGTAAACAAA
AATACTTTGTTGATTTGTAA

Upstream 100 bases:

>100_bases
CAAAATTGTTTTCAAAAAAGACGGCTTCAACGATTTAAAAAAAGATGTTGATGTGGCTTTGGCTTCTAAATAAACTTAAT
TCAAAACTAAACTAACCATA

Downstream 100 bases:

>100_bases
TTAAACATAACAAACCCGACAGGTTTTTCATATCAAAAATAAATTACCTCCAGCTTTAGCTGGAGGTTTTAAAAATTAAA
AGTAAAGAAGGCTTTAGCTA

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MAVYKKITKIVISILIVLLILAAFLFWPINTDGTLIQPDQKLAEGKAAFLSQKDTSAASEKKPNIIILLADDLGKYDISL
YGGKSTPTPQIDSLAASGVTFTDGYVSSSICSPSRAGLLTGRYQERFGHEYQPGDRYPKNNLEYYAFKYLLNTNSWRLNP
KIEYPNDASIATQGLPKSEITFADLAKKQGYSTAIIGKWHLGHTKGFFPLDRGFDYHYGFYQAFSLFAPEDNNPDIINHH
HTDFTDKTIWGNGRVGTGQIRRDSTIIDEKKYLTEKFAEEAEAFIDKNKNKPFLLYVPFNAPHTPFQVRKKYYDRFPNVK
DENKRVYFAMISALDDAIGLIRAKVKKEGLEENTLIFFASDNGGADYTYATTNAPLKGGKFSHFEGGVNVPFALSWKGKI
KPHTIYKTPVSSLDIFSTIAAVTHSGLPKDRVYDGVDLVDVVNNNKQAHQNLYWRSGDAKAIRSGDWKLIISGKTHETWL
YNLAKDKSETTDLASKNPEKVKELQTALQNWEKGLIKPLWPNLTYYEFDFGKQKYFVDL

Sequences:

>Translated_539_residues
MAVYKKITKIVISILIVLLILAAFLFWPINTDGTLIQPDQKLAEGKAAFLSQKDTSAASEKKPNIIILLADDLGKYDISL
YGGKSTPTPQIDSLAASGVTFTDGYVSSSICSPSRAGLLTGRYQERFGHEYQPGDRYPKNNLEYYAFKYLLNTNSWRLNP
KIEYPNDASIATQGLPKSEITFADLAKKQGYSTAIIGKWHLGHTKGFFPLDRGFDYHYGFYQAFSLFAPEDNNPDIINHH
HTDFTDKTIWGNGRVGTGQIRRDSTIIDEKKYLTEKFAEEAEAFIDKNKNKPFLLYVPFNAPHTPFQVRKKYYDRFPNVK
DENKRVYFAMISALDDAIGLIRAKVKKEGLEENTLIFFASDNGGADYTYATTNAPLKGGKFSHFEGGVNVPFALSWKGKI
KPHTIYKTPVSSLDIFSTIAAVTHSGLPKDRVYDGVDLVDVVNNNKQAHQNLYWRSGDAKAIRSGDWKLIISGKTHETWL
YNLAKDKSETTDLASKNPEKVKELQTALQNWEKGLIKPLWPNLTYYEFDFGKQKYFVDL
>Mature_538_residues
AVYKKITKIVISILIVLLILAAFLFWPINTDGTLIQPDQKLAEGKAAFLSQKDTSAASEKKPNIIILLADDLGKYDISLY
GGKSTPTPQIDSLAASGVTFTDGYVSSSICSPSRAGLLTGRYQERFGHEYQPGDRYPKNNLEYYAFKYLLNTNSWRLNPK
IEYPNDASIATQGLPKSEITFADLAKKQGYSTAIIGKWHLGHTKGFFPLDRGFDYHYGFYQAFSLFAPEDNNPDIINHHH
TDFTDKTIWGNGRVGTGQIRRDSTIIDEKKYLTEKFAEEAEAFIDKNKNKPFLLYVPFNAPHTPFQVRKKYYDRFPNVKD
ENKRVYFAMISALDDAIGLIRAKVKKEGLEENTLIFFASDNGGADYTYATTNAPLKGGKFSHFEGGVNVPFALSWKGKIK
PHTIYKTPVSSLDIFSTIAAVTHSGLPKDRVYDGVDLVDVVNNNKQAHQNLYWRSGDAKAIRSGDWKLIISGKTHETWLY
NLAKDKSETTDLASKNPEKVKELQTALQNWEKGLIKPLWPNLTYYEFDFGKQKYFVDL

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=409, Percent_Identity=29.8288508557457, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI38569405, Length=524, Percent_Identity=27.4809160305344, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI45430057, Length=415, Percent_Identity=29.6385542168675, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI109389362, Length=523, Percent_Identity=27.5334608030593, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI38569407, Length=340, Percent_Identity=32.0588235294118, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI59797060, Length=512, Percent_Identity=27.1484375, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI146229331, Length=482, Percent_Identity=27.8008298755187, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI146229329, Length=482, Percent_Identity=27.8008298755187, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI6005990, Length=482, Percent_Identity=27.8008298755187, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI146229324, Length=482, Percent_Identity=27.8008298755187, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI71852584, Length=480, Percent_Identity=26.4583333333333, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI58743319, Length=460, Percent_Identity=27.1739130434783, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI157266309, Length=453, Percent_Identity=27.5938189845475, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI53831991, Length=177, Percent_Identity=41.8079096045198, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI71852586, Length=311, Percent_Identity=28.2958199356913, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI31742482, Length=180, Percent_Identity=37.2222222222222, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI146229327, Length=369, Percent_Identity=25.7452574525745, Blast_Score=91, Evalue=4e-18,
Organism=Escherichia coli, GI87081924, Length=551, Percent_Identity=26.497277676951, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI1790233, Length=525, Percent_Identity=26.8571428571429, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1790112, Length=408, Percent_Identity=24.7549019607843, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115533416, Length=511, Percent_Identity=27.5929549902153, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI115533418, Length=500, Percent_Identity=27.6, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17559078, Length=178, Percent_Identity=35.3932584269663, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24666175, Length=399, Percent_Identity=29.5739348370927, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281366397, Length=491, Percent_Identity=28.5132382892057, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI281366395, Length=491, Percent_Identity=28.5132382892057, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24666163, Length=491, Percent_Identity=28.5132382892057, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24666109, Length=441, Percent_Identity=29.4784580498866, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281363223, Length=441, Percent_Identity=28.3446712018141, Blast_Score=149, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 60885; Mature: 60754

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYKKITKIVISILIVLLILAAFLFWPINTDGTLIQPDQKLAEGKAAFLSQKDTSAASE
CHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCHHHHCCHHHHHCCCCCCCHHC
KKPNIIILLADDLGKYDISLYGGKSTPTPQIDSLAASGVTFTDGYVSSSICSPSRAGLLT
CCCCEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHCCCEEECCCCHHCCCCCCCCCEEE
GRYQERFGHEYQPGDRYPKNNLEYYAFKYLLNTNSWRLNPKIEYPNDASIATQGLPKSEI
CHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEECCEECCCCCCCHHHCCCCCCCC
TFADLAKKQGYSTAIIGKWHLGHTKGFFPLDRGFDYHYGFYQAFSLFAPEDNNPDIINHH
HHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHEEECCCCCCCCCCCCC
HTDFTDKTIWGNGRVGTGQIRRDSTIIDEKKYLTEKFAEEAEAFIDKNKNKPFLLYVPFN
CCCCCCCEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
APHTPFQVRKKYYDRFPNVKDENKRVYFAMISALDDAIGLIRAKVKKEGLEENTLIFFAS
CCCCHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
DNGGADYTYATTNAPLKGGKFSHFEGGVNVPFALSWKGKIKPHTIYKTPVSSLDIFSTIA
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCHHHHHHHHH
AVTHSGLPKDRVYDGVDLVDVVNNNKQAHQNLYWRSGDAKAIRSGDWKLIISGKTHETWL
HHHHCCCCHHHHCCCCCEEEECCCCHHHHHCCEEECCCCCEEECCCEEEEEECCCCCHHH
YNLAKDKSETTDLASKNPEKVKELQTALQNWEKGLIKPLWPNLTYYEFDFGKQKYFVDL
HHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEC
>Mature Secondary Structure 
AVYKKITKIVISILIVLLILAAFLFWPINTDGTLIQPDQKLAEGKAAFLSQKDTSAASE
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCHHHHCCHHHHHCCCCCCCHHC
KKPNIIILLADDLGKYDISLYGGKSTPTPQIDSLAASGVTFTDGYVSSSICSPSRAGLLT
CCCCEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHCCCEEECCCCHHCCCCCCCCCEEE
GRYQERFGHEYQPGDRYPKNNLEYYAFKYLLNTNSWRLNPKIEYPNDASIATQGLPKSEI
CHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEECCEECCCCCCCHHHCCCCCCCC
TFADLAKKQGYSTAIIGKWHLGHTKGFFPLDRGFDYHYGFYQAFSLFAPEDNNPDIINHH
HHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHEEECCCCCCCCCCCCC
HTDFTDKTIWGNGRVGTGQIRRDSTIIDEKKYLTEKFAEEAEAFIDKNKNKPFLLYVPFN
CCCCCCCEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
APHTPFQVRKKYYDRFPNVKDENKRVYFAMISALDDAIGLIRAKVKKEGLEENTLIFFAS
CCCCHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
DNGGADYTYATTNAPLKGGKFSHFEGGVNVPFALSWKGKIKPHTIYKTPVSSLDIFSTIA
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCHHHHHHHHH
AVTHSGLPKDRVYDGVDLVDVVNNNKQAHQNLYWRSGDAKAIRSGDWKLIISGKTHETWL
HHHHCCCCHHHHCCCCCEEEECCCCHHHHHCCEEECCCCCEEECCCEEEEEECCCCCHHH
YNLAKDKSETTDLASKNPEKVKELQTALQNWEKGLIKPLWPNLTYYEFDFGKQKYFVDL
HHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]