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The map label for this gene is anr [H]

Identifier: 146302359

GI number: 146302359

Start: 5599046

End: 5599750

Strand: Reverse

Name: anr [H]

Synonym: Fjoh_4632

Alternate gene names: 146302359

Gene position: 5599750-5599046 (Counterclockwise)

Preceding gene: 146302363

Following gene: 146302350

Centisome position: 91.85

GC content: 34.18

Gene sequence:

>705_bases
ATGAAAGAAGAGCAAGCCATTTGTTATTCCTGTGTCAATGAAAATTGTTTTATAAAAAAACACTTGTATTTGGAGCAGAT
GAAAGCTTATATTTCTAAAAAGCAAAGTATTATTTGTAAAAAATCAGATCGGTTTATTACAGAAGGCGCTCCTTTGCAGG
GACTTTATTTTATATGTAAAGGAAAAGCCAAAACCATAAAAACGGGTATTAATGGCCGTGAGCAAATCGTTCGTTTAACT
ACTAATGGTGATATTATTGGTTTTCGCGGATTTGGAACGAGTAAACGTTATTTAATTGGTGCTTATGCACTAGAAGATAC
TGTTTTATGCAATTTCAGCAACGAGACTATGCTTGAAATTTTACAGCACGTTCCTGAGTTTACGTATGCTTTAATGTTGT
TCTATGCCGAAGAATTGAACAAAAGTGAAAATAACATCCGCAAGATTGCGCACATGAATGTTCGTGAACGTGTAATTGAT
TTGTTACTTTATATCCATCGTAAATTCGGACAAACGAATGGTTTGATTGATATTGAGCTTTCTCGAAAAGAAATTGCGGA
TTTTGCAGGAACTACAGAAGAACAGGCAATCCGTATTTTATCAAGTCTCAAAAAAGAATCGTTGATTAAAACGGAAGGGA
AACGTGTTGGGATTTTGGATGTTGAGGAATTACGTTCTGAAATTATGGAGCATAAGTATTTTTAG

Upstream 100 bases:

>100_bases
CGTATTTATACGTATTTTTTTGATTTATTTTTTTATTTTTGATTGAAAATAAATGAGGAACAACATCTTAGTTTTTTAAT
ATACTTAAAGTTTAAGACTC

Downstream 100 bases:

>100_bases
TGAGGGACAAAGTTACAAAGGGGCAAAGCTGCAAAGGTTTTTGATTGTAGAGACGCACTGCAGTGAGTTTTTACTGTATG
CGTCTCTACGTCGAGTGTAA

Product: CRP/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKEEQAICYSCVNENCFIKKHLYLEQMKAYISKKQSIICKKSDRFITEGAPLQGLYFICKGKAKTIKTGINGREQIVRLT
TNGDIIGFRGFGTSKRYLIGAYALEDTVLCNFSNETMLEILQHVPEFTYALMLFYAEELNKSENNIRKIAHMNVRERVID
LLLYIHRKFGQTNGLIDIELSRKEIADFAGTTEEQAIRILSSLKKESLIKTEGKRVGILDVEELRSEIMEHKYF

Sequences:

>Translated_234_residues
MKEEQAICYSCVNENCFIKKHLYLEQMKAYISKKQSIICKKSDRFITEGAPLQGLYFICKGKAKTIKTGINGREQIVRLT
TNGDIIGFRGFGTSKRYLIGAYALEDTVLCNFSNETMLEILQHVPEFTYALMLFYAEELNKSENNIRKIAHMNVRERVID
LLLYIHRKFGQTNGLIDIELSRKEIADFAGTTEEQAIRILSSLKKESLIKTEGKRVGILDVEELRSEIMEHKYF
>Mature_234_residues
MKEEQAICYSCVNENCFIKKHLYLEQMKAYISKKQSIICKKSDRFITEGAPLQGLYFICKGKAKTIKTGINGREQIVRLT
TNGDIIGFRGFGTSKRYLIGAYALEDTVLCNFSNETMLEILQHVPEFTYALMLFYAEELNKSENNIRKIAHMNVRERVID
LLLYIHRKFGQTNGLIDIELSRKEIADFAGTTEEQAIRILSSLKKESLIKTEGKRVGILDVEELRSEIMEHKYF

Specific function: Transcriptional activator of anaerobic gene expression [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=223, Percent_Identity=25.1121076233184, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26996; Mature: 26996

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEEQAICYSCVNENCFIKKHLYLEQMKAYISKKQSIICKKSDRFITEGAPLQGLYFICK
CCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCCCCCEEEEEC
GKAKTIKTGINGREQIVRLTTNGDIIGFRGFGTSKRYLIGAYALEDTVLCNFSNETMLEI
CCCCEEECCCCCCHHEEEEECCCCEEEEECCCCCCCEEEEEEEECCEEEEECCCHHHHHH
LQHVPEFTYALMLFYAEELNKSENNIRKIAHMNVRERVIDLLLYIHRKFGQTNGLIDIEL
HHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
SRKEIADFAGTTEEQAIRILSSLKKESLIKTEGKRVGILDVEELRSEIMEHKYF
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEEQAICYSCVNENCFIKKHLYLEQMKAYISKKQSIICKKSDRFITEGAPLQGLYFICK
CCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCCCCCEEEEEC
GKAKTIKTGINGREQIVRLTTNGDIIGFRGFGTSKRYLIGAYALEDTVLCNFSNETMLEI
CCCCEEECCCCCCHHEEEEECCCCEEEEECCCCCCCEEEEEEEECCEEEEECCCHHHHHH
LQHVPEFTYALMLFYAEELNKSENNIRKIAHMNVRERVIDLLLYIHRKFGQTNGLIDIEL
HHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
SRKEIADFAGTTEEQAIRILSSLKKESLIKTEGKRVGILDVEELRSEIMEHKYF
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1787797; 1787798; 10984043 [H]