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The map label for this gene is argD [H]

Identifier: 146301175

GI number: 146301175

Start: 4100708

End: 4101847

Strand: Reverse

Name: argD [H]

Synonym: Fjoh_3433

Alternate gene names: 146301175

Gene position: 4101847-4100708 (Counterclockwise)

Preceding gene: 146301176

Following gene: 146301174

Centisome position: 67.28

GC content: 34.39

Gene sequence:

>1140_bases
ATGAACTTATTCAACGTTTACCCATTATACGACATAACTCCAGTAAAAGCAGTAGATTGTACCATTATTGACGACAAAGG
AGTAGAATATTTAGATTTATACAGCGGACATGGTGTGATTTCTATCGGACACACACAGCCGGATTATGTAGCAAAATTGA
AAAATCAATTAGACCATTTAGGATTTTATTCGAATGCAATTCAGAATCCTTTGCAGGTAGAATTGGCTCAGAAATTAGGA
AAACTTTCTGGTCTTGAAGATTACGAATTGTTTTTATGCAGTTCTGGTGCTGAAGCCAACGAAAATGCTTTAAAATTAGC
TTCTTTCCACAACGGAAAATCAAGAGTTGTAGCTTTTGATAATTCTTTCCACGGAAGAACTTCTGCGGCAGTTGCAGTTA
CTGATAACAAAAAAATCGTTGCGCCATTAAATGCACAACAAAAAGTTACTTTTTTACCACTAAACCAAATCGAATTAGTT
GAAGCTGAATTAGCTAAAGGAGATGTTACAGCAGTAATTATCGAAGGAATTCAAGGAGTTGGAGGTTTAGACCAAGGAAC
AACAGAGTTTTTTCAGGCTTTAGAAAAAGCATGTAAAAAACACGATGTTGTTTTTATTTTAGACGAAGTACAGTCAGGAT
ACGGAAGAAGCGGAAAATTCTTCGCTTTCCAACATCACGGAATCAACGCTGATATAATTTCAGTTGCGAAAGGAATGGGG
AACGGTTTCCCTGTTGGAGCGATTCTAATTTCTCCAAAATTTGAAGCAAGTTTTGGATTATTAGGCACTACTTTCGGCGG
AAGCCATTTGTCTTGTGCTGCAGGAATTGCAGTTTTAGATGTAATTGAAAAACTGGATTTACAGAAAAATGTAAATGAAG
TTTATGAATATTTCTTAGAAAAAATCAAAGAAGTTGACGGAATCAAACAAGTAAAAGGAAAAGGCTTAATGCTTGGAGTA
GAGTTTGATTTTGATGTTGCAGCTTTAAGAAAGAAATTAATCATCGAAAAACACATTTTTACAGGAAGCGCAAACAATAA
AAATCTATTAAGAATTTTACCGCCTTTGACTGTCAAAAAAGCAGATATCGATACGTTTGTAAAAGCTTTAAAAGAAAGTT
TAGAAGAATTAAAAAACTAA

Upstream 100 bases:

>100_bases
TTTTAATTTTAGTTGATAGTTGTTGGTTTATAGTTGATAGATATCGAACAAAAACCAACAACCATCAACCATCAACAATA
AACTAACAACTAAAAAAAAG

Downstream 100 bases:

>100_bases
TTCTCGTTACGTTAAACCTGACGGGTTTTTAAAACCCGTTAGGTTTAAAATAAAGTTTCCGAAAAAGAAACAACCAAAAA
ACAACCAACCCACTTGAAAT

Product: class III aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNLFNVYPLYDITPVKAVDCTIIDDKGVEYLDLYSGHGVISIGHTQPDYVAKLKNQLDHLGFYSNAIQNPLQVELAQKLG
KLSGLEDYELFLCSSGAEANENALKLASFHNGKSRVVAFDNSFHGRTSAAVAVTDNKKIVAPLNAQQKVTFLPLNQIELV
EAELAKGDVTAVIIEGIQGVGGLDQGTTEFFQALEKACKKHDVVFILDEVQSGYGRSGKFFAFQHHGINADIISVAKGMG
NGFPVGAILISPKFEASFGLLGTTFGGSHLSCAAGIAVLDVIEKLDLQKNVNEVYEYFLEKIKEVDGIKQVKGKGLMLGV
EFDFDVAALRKKLIIEKHIFTGSANNKNLLRILPPLTVKKADIDTFVKALKESLEELKN

Sequences:

>Translated_379_residues
MNLFNVYPLYDITPVKAVDCTIIDDKGVEYLDLYSGHGVISIGHTQPDYVAKLKNQLDHLGFYSNAIQNPLQVELAQKLG
KLSGLEDYELFLCSSGAEANENALKLASFHNGKSRVVAFDNSFHGRTSAAVAVTDNKKIVAPLNAQQKVTFLPLNQIELV
EAELAKGDVTAVIIEGIQGVGGLDQGTTEFFQALEKACKKHDVVFILDEVQSGYGRSGKFFAFQHHGINADIISVAKGMG
NGFPVGAILISPKFEASFGLLGTTFGGSHLSCAAGIAVLDVIEKLDLQKNVNEVYEYFLEKIKEVDGIKQVKGKGLMLGV
EFDFDVAALRKKLIIEKHIFTGSANNKNLLRILPPLTVKKADIDTFVKALKESLEELKN
>Mature_379_residues
MNLFNVYPLYDITPVKAVDCTIIDDKGVEYLDLYSGHGVISIGHTQPDYVAKLKNQLDHLGFYSNAIQNPLQVELAQKLG
KLSGLEDYELFLCSSGAEANENALKLASFHNGKSRVVAFDNSFHGRTSAAVAVTDNKKIVAPLNAQQKVTFLPLNQIELV
EAELAKGDVTAVIIEGIQGVGGLDQGTTEFFQALEKACKKHDVVFILDEVQSGYGRSGKFFAFQHHGINADIISVAKGMG
NGFPVGAILISPKFEASFGLLGTTFGGSHLSCAAGIAVLDVIEKLDLQKNVNEVYEYFLEKIKEVDGIKQVKGKGLMLGV
EFDFDVAALRKKLIIEKHIFTGSANNKNLLRILPPLTVKKADIDTFVKALKESLEELKN

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=414, Percent_Identity=28.743961352657, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4557809, Length=372, Percent_Identity=26.6129032258064, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI37574042, Length=407, Percent_Identity=28.992628992629, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI24119277, Length=415, Percent_Identity=28.433734939759, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442705, Length=412, Percent_Identity=29.126213592233, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI226442709, Length=380, Percent_Identity=28.9473684210526, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=26.3333333333333, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI188536080, Length=423, Percent_Identity=24.822695035461, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38679950, Length=423, Percent_Identity=24.822695035461, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38679946, Length=423, Percent_Identity=24.822695035461, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1789759, Length=378, Percent_Identity=31.2169312169312, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI145693181, Length=385, Percent_Identity=30.9090909090909, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1788044, Length=396, Percent_Identity=31.3131313131313, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=31.8518518518519, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789016, Length=403, Percent_Identity=29.2803970223325, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1786991, Length=418, Percent_Identity=25.8373205741627, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786349, Length=334, Percent_Identity=23.0538922155689, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32564660, Length=413, Percent_Identity=30.9927360774818, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25144271, Length=374, Percent_Identity=28.0748663101604, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=257, Percent_Identity=29.9610894941634, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71992977, Length=409, Percent_Identity=26.4058679706601, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17541228, Length=429, Percent_Identity=25.4079254079254, Blast_Score=95, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=391, Percent_Identity=34.0153452685422, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6323470, Length=410, Percent_Identity=27.5609756097561, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324386, Length=454, Percent_Identity=27.5330396475771, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=447, Percent_Identity=24.8322147651007, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28574759, Length=417, Percent_Identity=30.6954436450839, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI161085790, Length=412, Percent_Identity=29.8543689320388, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21356575, Length=403, Percent_Identity=28.5359801488834, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357415, Length=389, Percent_Identity=24.1645244215938, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281366494, Length=286, Percent_Identity=24.4755244755245, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24667139, Length=286, Percent_Identity=24.4755244755245, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24667143, Length=286, Percent_Identity=24.4755244755245, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41275; Mature: 41275

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFNVYPLYDITPVKAVDCTIIDDKGVEYLDLYSGHGVISIGHTQPDYVAKLKNQLDHL
CCCEEECCCCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHC
GFYSNAIQNPLQVELAQKLGKLSGLEDYELFLCSSGAEANENALKLASFHNGKSRVVAFD
CHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEECCCCEEEEEEC
NSFHGRTSAAVAVTDNKKIVAPLNAQQKVTFLPLNQIELVEAELAKGDVTAVIIEGIQGV
CCCCCCCCEEEEEECCCEEEECCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCC
GGLDQGTTEFFQALEKACKKHDVVFILDEVQSGYGRSGKFFAFQHHGINADIISVAKGMG
CCCCCCHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCCEEEEEECCCCHHHHHHHHHCC
NGFPVGAILISPKFEASFGLLGTTFGGSHLSCAAGIAVLDVIEKLDLQKNVNEVYEYFLE
CCCCEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KIKEVDGIKQVKGKGLMLGVEFDFDVAALRKKLIIEKHIFTGSANNKNLLRILPPLTVKK
HHHHHCCHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHEEECCCCCCCEEEECCCCEEEC
ADIDTFVKALKESLEELKN
CCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLFNVYPLYDITPVKAVDCTIIDDKGVEYLDLYSGHGVISIGHTQPDYVAKLKNQLDHL
CCCEEECCCCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHC
GFYSNAIQNPLQVELAQKLGKLSGLEDYELFLCSSGAEANENALKLASFHNGKSRVVAFD
CHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEECCCCEEEEEEC
NSFHGRTSAAVAVTDNKKIVAPLNAQQKVTFLPLNQIELVEAELAKGDVTAVIIEGIQGV
CCCCCCCCEEEEEECCCEEEECCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCC
GGLDQGTTEFFQALEKACKKHDVVFILDEVQSGYGRSGKFFAFQHHGINADIISVAKGMG
CCCCCCHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCCEEEEEECCCCHHHHHHHHHCC
NGFPVGAILISPKFEASFGLLGTTFGGSHLSCAAGIAVLDVIEKLDLQKNVNEVYEYFLE
CCCCEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KIKEVDGIKQVKGKGLMLGVEFDFDVAALRKKLIIEKHIFTGSANNKNLLRILPPLTVKK
HHHHHCCHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHEEECCCCCCCEEEECCCCEEEC
ADIDTFVKALKESLEELKN
CCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025667; 9384377 [H]