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The map label for this gene is argC

Identifier: 146301176

GI number: 146301176

Start: 4101942

End: 4102919

Strand: Reverse

Name: argC

Synonym: Fjoh_3434

Alternate gene names: 146301176

Gene position: 4102919-4101942 (Counterclockwise)

Preceding gene: 146301177

Following gene: 146301175

Centisome position: 67.3

GC content: 35.28

Gene sequence:

>978_bases
ATGATTAATGTCGGAATTATTGGTGGTTCGGGCTACACGGCCGGAGAACTCATCAGAATTTTAATGTATCACCCAAAAGT
AAACATCGATTTTGTTTACAGTACAACAAACGCCGGGAAACCGCTTTCTGTAGCGCACCACGATTTGATGGGTGATATTG
AAATGAATTTCACAGCTGAAATTAATCCAAATGTGAACGTTGTTTTCTTGTGTTTAGGACATGGAAAATCGATTTCATTT
TTGAAAGAAAATCAGTTCGCAAGTCACACCAAAATCATCGATTTAGGAAATGATTTCAGATTGAATAAAGACGCTCATTT
CGAAGGAAAAGATTTTGTTTACGGATTGCCAGAGATCAATAAAGCGGAAATCAAAAAGACAAATTATATCGCCAATCCAG
GCTGTTTTGCAACTGCTATTCAGTTGGCTTTATTACCTTTAGCAAAACACAATTTGTTGAATAATGATGTTCATATTAAT
GCTACAACCGGAAGTACAGGAGCAGGAGTAAGTCTTTCAGAAACTTCTCATTTCAGTTGGAGAAACAACAATATGTCGCA
TTATAAAGCTTTTGAGCATCAACATTTGGGAGAAATCGGAGAAAGCTTAGTTCAGTTGCAAGACGATTTTGACAGCGAGT
TGCTTTTTATTCCGAATAGAGGAGATTTTCCAAGAGGAATTTTTGCAACCTTATATACATTATGTGATGATAGTTTGGAA
CAATTGGTTGCAAAATATGAAGAGTTCTATAAAAATGAGCCTTTCGTAACTGTTACCACAACAAACATCAACATGAAACA
AGTGGTGCAAACGAATAAATGTATTATTAGTTTATTGAAAAAAGGAAACCGGGTTCTTATAACATCAATTATCGATAACT
TAACCAAAGGTGCTTCAGGACAAGCGATTCAAAACATGAATTTAATGTTCGGTTTAGAAGAAACCACAGGTTTACATTTG
AAACCAAGCGGATTTTAA

Upstream 100 bases:

>100_bases
GGCGAAATGAACAATGCCTGGACATCTGACGATGCAAAAGGATTTATCAAGATTTTAGGAAATGCACAAAACATATTCTC
ATCTGTAAACAAATTAGATC

Downstream 100 bases:

>100_bases
TTTTAGTTGATAGTTGTTGGTTTATAGTTGATAGATATCGAACAAAAACCAACAACCATCAACCATCAACAATAAACTAA
CAACTAAAAAAAAGATGAAC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MINVGIIGGSGYTAGELIRILMYHPKVNIDFVYSTTNAGKPLSVAHHDLMGDIEMNFTAEINPNVNVVFLCLGHGKSISF
LKENQFASHTKIIDLGNDFRLNKDAHFEGKDFVYGLPEINKAEIKKTNYIANPGCFATAIQLALLPLAKHNLLNNDVHIN
ATTGSTGAGVSLSETSHFSWRNNNMSHYKAFEHQHLGEIGESLVQLQDDFDSELLFIPNRGDFPRGIFATLYTLCDDSLE
QLVAKYEEFYKNEPFVTVTTTNINMKQVVQTNKCIISLLKKGNRVLITSIIDNLTKGASGQAIQNMNLMFGLEETTGLHL
KPSGF

Sequences:

>Translated_325_residues
MINVGIIGGSGYTAGELIRILMYHPKVNIDFVYSTTNAGKPLSVAHHDLMGDIEMNFTAEINPNVNVVFLCLGHGKSISF
LKENQFASHTKIIDLGNDFRLNKDAHFEGKDFVYGLPEINKAEIKKTNYIANPGCFATAIQLALLPLAKHNLLNNDVHIN
ATTGSTGAGVSLSETSHFSWRNNNMSHYKAFEHQHLGEIGESLVQLQDDFDSELLFIPNRGDFPRGIFATLYTLCDDSLE
QLVAKYEEFYKNEPFVTVTTTNINMKQVVQTNKCIISLLKKGNRVLITSIIDNLTKGASGQAIQNMNLMFGLEETTGLHL
KPSGF
>Mature_325_residues
MINVGIIGGSGYTAGELIRILMYHPKVNIDFVYSTTNAGKPLSVAHHDLMGDIEMNFTAEINPNVNVVFLCLGHGKSISF
LKENQFASHTKIIDLGNDFRLNKDAHFEGKDFVYGLPEINKAEIKKTNYIANPGCFATAIQLALLPLAKHNLLNNDVHIN
ATTGSTGAGVSLSETSHFSWRNNNMSHYKAFEHQHLGEIGESLVQLQDDFDSELLFIPNRGDFPRGIFATLYTLCDDSLE
QLVAKYEEFYKNEPFVTVTTTNINMKQVVQTNKCIISLLKKGNRVLITSIIDNLTKGASGQAIQNMNLMFGLEETTGLHL
KPSGF

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=33.0434782608696, Blast_Score=146, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320913, Length=330, Percent_Identity=29.3939393939394, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_FLAJ1 (A5FEC6)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001195767.1
- ProteinModelPortal:   A5FEC6
- SMR:   A5FEC6
- STRING:   A5FEC6
- GeneID:   5093682
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_3434
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   DTKKFME
- ProtClustDB:   PRK00436
- BioCyc:   FJOH376686:FJOH_3434-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh

EC number: =1.2.1.38

Molecular weight: Translated: 36015; Mature: 36015

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 135-135

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINVGIIGGSGYTAGELIRILMYHPKVNIDFVYSTTNAGKPLSVAHHDLMGDIEMNFTAE
CEEEEEECCCCCCHHHHHHHHEECCCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEEEEE
INPNVNVVFLCLGHGKSISFLKENQFASHTKIIDLGNDFRLNKDAHFEGKDFVYGLPEIN
ECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEECCCCEEECCCCCCCCCCEEEECCCCC
KAEIKKTNYIANPGCFATAIQLALLPLAKHNLLNNDVHINATTGSTGAGVSLSETSHFSW
HHHEECCCEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCEEE
RNNNMSHYKAFEHQHLGEIGESLVQLQDDFDSELLFIPNRGDFPRGIFATLYTLCDDSLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
QLVAKYEEFYKNEPFVTVTTTNINMKQVVQTNKCIISLLKKGNRVLITSIIDNLTKGASG
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCC
QAIQNMNLMFGLEETTGLHLKPSGF
CEEECCEEEEEECCCCCEEECCCCC
>Mature Secondary Structure
MINVGIIGGSGYTAGELIRILMYHPKVNIDFVYSTTNAGKPLSVAHHDLMGDIEMNFTAE
CEEEEEECCCCCCHHHHHHHHEECCCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEEEEE
INPNVNVVFLCLGHGKSISFLKENQFASHTKIIDLGNDFRLNKDAHFEGKDFVYGLPEIN
ECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEECCCCEEECCCCCCCCCCEEEECCCCC
KAEIKKTNYIANPGCFATAIQLALLPLAKHNLLNNDVHINATTGSTGAGVSLSETSHFSW
HHHEECCCEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCEEE
RNNNMSHYKAFEHQHLGEIGESLVQLQDDFDSELLFIPNRGDFPRGIFATLYTLCDDSLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
QLVAKYEEFYKNEPFVTVTTTNINMKQVVQTNKCIISLLKKGNRVLITSIIDNLTKGASG
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCC
QAIQNMNLMFGLEETTGLHLKPSGF
CEEECCEEEEEECCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA