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The map label for this gene is ptrB [H]

Identifier: 146300311

GI number: 146300311

Start: 3039258

End: 3041318

Strand: Direct

Name: ptrB [H]

Synonym: Fjoh_2556

Alternate gene names: 146300311

Gene position: 3039258-3041318 (Clockwise)

Preceding gene: 146300309

Following gene: 146300312

Centisome position: 49.85

GC content: 33.82

Gene sequence:

>2061_bases
ATGCAGAACGATATACTGGCTCCAAAGGCTAAAGAAATTCCAAAATCATTAAAGAAACATAAAGAAACAAGAATCGATAA
TTATTTTTGGCTGAATGACAGAGAAAATCCAGAAGTTATCGATTATCTGAATAAAGAAAACGAATACTACCAAAAATCGA
CCGCTCATACAAAAGGTTTACAAGAATCTTTATATGAGGAAATGAAAGGAAGAATTAAAGAAGACGATTCGTCTGTTCCT
TATTTCTACAACGGTTATTTCTACATTACACGATTTGAAACGGGACAGGATTACCCTATTTTCGCCAGAAAAAAAGGAAG
CCTTTCGGCAGATGAAGAAATTCTTTTTAATTGCAATGAATTAGCAAAAGGCCACGCGTATTTTAAATTAGGAGGTTTAA
GCATAAGTCCGGATAACAAATTTGCGACTTTTGGAACCGATATTGTAGGAAGAAGAATTTATACAATTCAAATTAAAAAC
CTCGAAACAGGAGAAATTCTGGCAGATAAAATCGAAAATGCTACAGGAGGATCAGTTTGGGCCAATGATAACAACACTAT
TTTTTATACCAAACAGGACGAAGTTACTTTAAGAGCTGATAAAATTTTCAGACATAAATTAAATACAGATTCAGCTTCTG
ACGTTTTGGTTTATAATGAAACCGACGATACTTTTAATGTTTCGGTAAACAAAGAAAAATCAAGAAAATATATTGTAATT
AGTTCAGGAAGTACTTTAACGACTGAATATAGAATTCTGAATTCTGATAATCCAGATGGAGAGTTTGAGGTATTTCAGCC
TCGTGTACGCGGTTTAGAATACAGTATTTCTCATTACGAAGATTCATTTTATATCTTAACGAATAAAGATAAAGCGACCA
ATTTTAAGCTGATGAAAACGCCTGAAAATAAAACAGGCAAAAAAAATTGGGTTGATGTGATTCCGCATAGAGAAGATGTT
TTATTAGAAGATATTGAGATCTTTAAAAACTATTTAGTGGTAGAGGAGCGTTCTAATGGTTTAAACCATATTAGAATTAT
GCCCTGGAATGACGAACCAGATTATTATCTGCCATTTGGAAGTGAAACTTATAGTGCTTTCACTACTACAAATATTGATT
TTGATACCGATATTCTGCGTTACAGTTATCAGTCGCTGGCAACACCTTCTTCGGTAATTGATTTTAATATGAAAACTAAA
ACCAAAGAGATCTTAAAAGAGCAGCAGGTTTTAGGCGGAAAATTTGATAAAGAAAATTATGTAGAAGAACGTGTTTGGGC
AACTGCCAGAGATGGCGTAAAAGTGCCAATTTCGATGATTTACCGAAAAGGGTTACAGAAAAACGGTAAAAATCCGTTAC
TTCTTTATGCTTACGGTTCATACGGAATTACAATGGATACTTATTTCTCATCAACTAGACTTTCTTTATTAGACCGCGGA
TTTGTTTATGCAATCGCGCATATTAGAGGAGGAGAGGACTTAGGAAGACAATGGTATGAGGATGGAAAACTGTTAAAAAA
GAAAAATACCTTTACAGATTTCATCGATTGCTCTAAATTTGTAATAGACGAGAAATATACTTCGCCAGAACATCTTTATG
CTGAAGGTGGATCTGCAGGAGGACTTTTAATGGGTGTTATTGTAAATGAAGCACCAGAATTATACAACGGCGTTATTGCT
CAGGTACCTTTTGTAGATGTTATTACAACAATGCTGGATGACAGTATTCCGCTTACAACAGGAGAATATGACGAATGGGG
AAACCCAAATAATAAAAAGTATTATGATTATATGTTGTCGTATTCACCTTACGACAATGTAAAAGCGCAAAATTATCCTA
ATATGTATGTGTCTACAGGATTACATGATTCGCAGGTACAATATTGGGAGCCAGCTAAATGGGTGGCCAAATTGAGAATT
TTAAAAACAAATAATAATCAATTGTTTTTAGATACTAATATGGATGCCGGACATGGCGGGGCTTCAGGACGTTTTGAGGC
TTTAAAAGACTTAGCAAAAGAATTTAGTTTTTTATTAGATTTAGAAAAAATTAAAAGCTAA

Upstream 100 bases:

>100_bases
GATTACAATAGAATATTTTATGAAAAATTTAATTTCGTTCTATATGTGATTGTAGTATTTTTGCGTCTCCGAATTAAAAA
CCTAATGCTTAATTAAATCA

Downstream 100 bases:

>100_bases
TTAGAAATTTTTTGTTAAATTTGCAACCTATCAAGGTTATTTAAAAATACCTTCGATTAACTATTTTTTTATGAAAGAAG
AAATAAACGCTTATAATAAT

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MQNDILAPKAKEIPKSLKKHKETRIDNYFWLNDRENPEVIDYLNKENEYYQKSTAHTKGLQESLYEEMKGRIKEDDSSVP
YFYNGYFYITRFETGQDYPIFARKKGSLSADEEILFNCNELAKGHAYFKLGGLSISPDNKFATFGTDIVGRRIYTIQIKN
LETGEILADKIENATGGSVWANDNNTIFYTKQDEVTLRADKIFRHKLNTDSASDVLVYNETDDTFNVSVNKEKSRKYIVI
SSGSTLTTEYRILNSDNPDGEFEVFQPRVRGLEYSISHYEDSFYILTNKDKATNFKLMKTPENKTGKKNWVDVIPHREDV
LLEDIEIFKNYLVVEERSNGLNHIRIMPWNDEPDYYLPFGSETYSAFTTTNIDFDTDILRYSYQSLATPSSVIDFNMKTK
TKEILKEQQVLGGKFDKENYVEERVWATARDGVKVPISMIYRKGLQKNGKNPLLLYAYGSYGITMDTYFSSTRLSLLDRG
FVYAIAHIRGGEDLGRQWYEDGKLLKKKNTFTDFIDCSKFVIDEKYTSPEHLYAEGGSAGGLLMGVIVNEAPELYNGVIA
QVPFVDVITTMLDDSIPLTTGEYDEWGNPNNKKYYDYMLSYSPYDNVKAQNYPNMYVSTGLHDSQVQYWEPAKWVAKLRI
LKTNNNQLFLDTNMDAGHGGASGRFEALKDLAKEFSFLLDLEKIKS

Sequences:

>Translated_686_residues
MQNDILAPKAKEIPKSLKKHKETRIDNYFWLNDRENPEVIDYLNKENEYYQKSTAHTKGLQESLYEEMKGRIKEDDSSVP
YFYNGYFYITRFETGQDYPIFARKKGSLSADEEILFNCNELAKGHAYFKLGGLSISPDNKFATFGTDIVGRRIYTIQIKN
LETGEILADKIENATGGSVWANDNNTIFYTKQDEVTLRADKIFRHKLNTDSASDVLVYNETDDTFNVSVNKEKSRKYIVI
SSGSTLTTEYRILNSDNPDGEFEVFQPRVRGLEYSISHYEDSFYILTNKDKATNFKLMKTPENKTGKKNWVDVIPHREDV
LLEDIEIFKNYLVVEERSNGLNHIRIMPWNDEPDYYLPFGSETYSAFTTTNIDFDTDILRYSYQSLATPSSVIDFNMKTK
TKEILKEQQVLGGKFDKENYVEERVWATARDGVKVPISMIYRKGLQKNGKNPLLLYAYGSYGITMDTYFSSTRLSLLDRG
FVYAIAHIRGGEDLGRQWYEDGKLLKKKNTFTDFIDCSKFVIDEKYTSPEHLYAEGGSAGGLLMGVIVNEAPELYNGVIA
QVPFVDVITTMLDDSIPLTTGEYDEWGNPNNKKYYDYMLSYSPYDNVKAQNYPNMYVSTGLHDSQVQYWEPAKWVAKLRI
LKTNNNQLFLDTNMDAGHGGASGRFEALKDLAKEFSFLLDLEKIKS
>Mature_686_residues
MQNDILAPKAKEIPKSLKKHKETRIDNYFWLNDRENPEVIDYLNKENEYYQKSTAHTKGLQESLYEEMKGRIKEDDSSVP
YFYNGYFYITRFETGQDYPIFARKKGSLSADEEILFNCNELAKGHAYFKLGGLSISPDNKFATFGTDIVGRRIYTIQIKN
LETGEILADKIENATGGSVWANDNNTIFYTKQDEVTLRADKIFRHKLNTDSASDVLVYNETDDTFNVSVNKEKSRKYIVI
SSGSTLTTEYRILNSDNPDGEFEVFQPRVRGLEYSISHYEDSFYILTNKDKATNFKLMKTPENKTGKKNWVDVIPHREDV
LLEDIEIFKNYLVVEERSNGLNHIRIMPWNDEPDYYLPFGSETYSAFTTTNIDFDTDILRYSYQSLATPSSVIDFNMKTK
TKEILKEQQVLGGKFDKENYVEERVWATARDGVKVPISMIYRKGLQKNGKNPLLLYAYGSYGITMDTYFSSTRLSLLDRG
FVYAIAHIRGGEDLGRQWYEDGKLLKKKNTFTDFIDCSKFVIDEKYTSPEHLYAEGGSAGGLLMGVIVNEAPELYNGVIA
QVPFVDVITTMLDDSIPLTTGEYDEWGNPNNKKYYDYMLSYSPYDNVKAQNYPNMYVSTGLHDSQVQYWEPAKWVAKLRI
LKTNNNQLFLDTNMDAGHGGASGRFEALKDLAKEFSFLLDLEKIKS

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172420, Length=538, Percent_Identity=27.3234200743494, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI284172413, Length=538, Percent_Identity=27.3234200743494, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI70778815, Length=538, Percent_Identity=27.3234200743494, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI284172438, Length=538, Percent_Identity=27.3234200743494, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI284172431, Length=538, Percent_Identity=27.3234200743494, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI41349456, Length=701, Percent_Identity=22.9671897289586, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI108860686, Length=217, Percent_Identity=36.405529953917, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI108860692, Length=255, Percent_Identity=34.9019607843137, Blast_Score=152, Evalue=9e-37,
Organism=Escherichia coli, GI1788150, Length=682, Percent_Identity=46.9208211143695, Blast_Score=654, Evalue=0.0,
Organism=Drosophila melanogaster, GI221510989, Length=669, Percent_Identity=24.2152466367713, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24583414, Length=705, Percent_Identity=23.9716312056738, Blast_Score=171, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78922; Mature: 78922

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNDILAPKAKEIPKSLKKHKETRIDNYFWLNDRENPEVIDYLNKENEYYQKSTAHTKGL
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHH
QESLYEEMKGRIKEDDSSVPYFYNGYFYITRFETGQDYPIFARKKGSLSADEEILFNCNE
HHHHHHHHHCCCCCCCCCCCEEECCEEEEEEECCCCCCCEEEECCCCCCCCHHHEEECHH
LAKGHAYFKLGGLSISPDNKFATFGTDIVGRRIYTIQIKNLETGEILADKIENATGGSVW
HCCCCEEEEECCEEECCCCCEEECCCHHHCCEEEEEEEECCCCCHHHHHHHCCCCCCEEE
ANDNNTIFYTKQDEVTLRADKIFRHKLNTDSASDVLVYNETDDTFNVSVNKEKSRKYIVI
ECCCCEEEEEECCCEEEEHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCCEEEEE
SSGSTLTTEYRILNSDNPDGEFEVFQPRVRGLEYSISHYEDSFYILTNKDKATNFKLMKT
ECCCEEEEEEEEECCCCCCCCEEEECHHHCCEEEEEEECCCEEEEEECCCCCCCEEEEEC
PENKTGKKNWVDVIPHREDVLLEDIEIFKNYLVVEERSNGLNHIRIMPWNDEPDYYLPFG
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHEEEEEECCCCCCEEEEEECCCCCCEEECCC
SETYSAFTTTNIDFDTDILRYSYQSLATPSSVIDFNMKTKTKEILKEQQVLGGKFDKENY
CCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHH
VEERVWATARDGVKVPISMIYRKGLQKNGKNPLLLYAYGSYGITMDTYFSSTRLSLLDRG
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCHHHHHHHCC
FVYAIAHIRGGEDLGRQWYEDGKLLKKKNTFTDFIDCSKFVIDEKYTSPEHLYAEGGSAG
EEEEEEEECCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHEEECCCCCCCCEEECCCCCC
GLLMGVIVNEAPELYNGVIAQVPFVDVITTMLDDSIPLTTGEYDEWGNPNNKKYYDYMLS
CEEEEEEHHCCCHHHCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEE
YSPYDNVKAQNYPNMYVSTGLHDSQVQYWEPAKWVAKLRILKTNNNQLFLDTNMDAGHGG
ECCCCCCCCCCCCCEEEECCCCCCCCCEECCHHHEEEEEEEEECCCEEEEECCCCCCCCC
ASGRFEALKDLAKEFSFLLDLEKIKS
CCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQNDILAPKAKEIPKSLKKHKETRIDNYFWLNDRENPEVIDYLNKENEYYQKSTAHTKGL
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHH
QESLYEEMKGRIKEDDSSVPYFYNGYFYITRFETGQDYPIFARKKGSLSADEEILFNCNE
HHHHHHHHHCCCCCCCCCCCEEECCEEEEEEECCCCCCCEEEECCCCCCCCHHHEEECHH
LAKGHAYFKLGGLSISPDNKFATFGTDIVGRRIYTIQIKNLETGEILADKIENATGGSVW
HCCCCEEEEECCEEECCCCCEEECCCHHHCCEEEEEEEECCCCCHHHHHHHCCCCCCEEE
ANDNNTIFYTKQDEVTLRADKIFRHKLNTDSASDVLVYNETDDTFNVSVNKEKSRKYIVI
ECCCCEEEEEECCCEEEEHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCCEEEEE
SSGSTLTTEYRILNSDNPDGEFEVFQPRVRGLEYSISHYEDSFYILTNKDKATNFKLMKT
ECCCEEEEEEEEECCCCCCCCEEEECHHHCCEEEEEEECCCEEEEEECCCCCCCEEEEEC
PENKTGKKNWVDVIPHREDVLLEDIEIFKNYLVVEERSNGLNHIRIMPWNDEPDYYLPFG
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHEEEEEECCCCCCEEEEEECCCCCCEEECCC
SETYSAFTTTNIDFDTDILRYSYQSLATPSSVIDFNMKTKTKEILKEQQVLGGKFDKENY
CCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHH
VEERVWATARDGVKVPISMIYRKGLQKNGKNPLLLYAYGSYGITMDTYFSSTRLSLLDRG
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCHHHHHHHCC
FVYAIAHIRGGEDLGRQWYEDGKLLKKKNTFTDFIDCSKFVIDEKYTSPEHLYAEGGSAG
EEEEEEEECCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHEEECCCCCCCCEEECCCCCC
GLLMGVIVNEAPELYNGVIAQVPFVDVITTMLDDSIPLTTGEYDEWGNPNNKKYYDYMLS
CEEEEEEHHCCCHHHCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEE
YSPYDNVKAQNYPNMYVSTGLHDSQVQYWEPAKWVAKLRILKTNNNQLFLDTNMDAGHGG
ECCCCCCCCCCCCCEEEECCCCCCCCCEECCHHHEEEEEEEEECCCEEEEECCCCCCCCC
ASGRFEALKDLAKEFSFLLDLEKIKS
CCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]