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The map label for this gene is pncB [H]

Identifier: 146300227

GI number: 146300227

Start: 2958902

End: 2960077

Strand: Direct

Name: pncB [H]

Synonym: Fjoh_2472

Alternate gene names: 146300227

Gene position: 2958902-2960077 (Clockwise)

Preceding gene: 146300226

Following gene: 146300228

Centisome position: 48.53

GC content: 33.08

Gene sequence:

>1176_bases
ATGGAAGCGACTTTTCTGAAATCGATCTTAGATAATGATTTCTATAAATTTACGATGCAGCATGCTGTAATTAAACTTTT
TCCAAAAGCAAAAGTTCGTTACGGATTTATAAATCGTGGTAAACATATCTTTCCTGAAGGATTTGCAGATTTACTTCGAC
GTTCAGTTGATGCATTGTCTGAACTTCGTTTAACAAAAGAAGAAAAAAGTTATTTAGCTCATTATTGTCCTTATCTCGAC
CCAACCTATTTAGATTTTCTGCAAGGATATAGTTTTGATCCATCTGAAGTTCAAATTAGTCAGGAAGGTTCAGAAATTTC
AGTAACCGTAGAAGGTTATTGGTACAGAACTATTTTATGGGAAGTTCCTTTAATGGCTTTGATTTCGGAACTTTTTTATA
AATCAAATCATTTAATTCGTTTAAATGATGAAGCCATAAAAGAGCTGACAAAAGAGAAAATTGATAATTATAATAAATTA
GGAGTTTCGATTTTAGAATTTGGAACAAGAAGACGTCATTCTTACGATGTTCATGATTTAGTAAATGAAACTTTAAGAAC
CTACGGAGGAAACAGTTTTATTGGAACCAGCAACGTACACTTTGCAATGGTTAACAATAGAAGGCCTTTGGGAACTCACG
CTCATGAATGGTTTATGTTTCATGCTGCTCAATATGGTTTTCAGGTAGCGAATTTTATAAGTCTCGAAAACTGGACAAAA
GTCTACGGAGGTGATCTCGGAATTGCTTTAACAGATACTTATACTACAGAAATATTTTTCAACCAATTCGATAAAAAATA
TTCCAAACTTTTTGACGGCGTTCGACATGACAGCGGTGATCCAATTGAGTTTGCCCAAAAAGTAATTTCTCATTATACCA
AAATGGGAATTGATCCAAAATCAAAAGTTATTGTTTTTTCAGATTCACTCAATTACGATAAAGTAAAAAAGATTGTTGAT
TTCTGTCAGGACAAAATAAAAATGTCATTTGGAATCGGGACAAATTTCACCAACGATGTTGGACTTCCAGCTATGAATAT
GGTTATAAAATTAACGGATACAAAACCTGATAATATACATTGGCAAGGTGTAGTTAAACTTTCTGACGAGAAAAATAAAA
ACACAGGAACGCCCGAAATGATTGCTTTGGCAAAAGAAGTACTGGGAATCAAATAG

Upstream 100 bases:

>100_bases
TTTTAAAGTAGTTTCAAAATAATTTATTTAAGGATTATACAAATTTTAATCTTTTCTGAAATTGCCGTATCTTAGCAAGA
ATGATTCGAATTTGAACACT

Downstream 100 bases:

>100_bases
TATTTTTTTTGACAAAAAAGCAGTTTTTTATAATTTTACCGCCCATTTTATTTTAAAATCAATTTAAATAGATTTTAAAC
TGTTATTATTCATAACAAAA

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MEATFLKSILDNDFYKFTMQHAVIKLFPKAKVRYGFINRGKHIFPEGFADLLRRSVDALSELRLTKEEKSYLAHYCPYLD
PTYLDFLQGYSFDPSEVQISQEGSEISVTVEGYWYRTILWEVPLMALISELFYKSNHLIRLNDEAIKELTKEKIDNYNKL
GVSILEFGTRRRHSYDVHDLVNETLRTYGGNSFIGTSNVHFAMVNNRRPLGTHAHEWFMFHAAQYGFQVANFISLENWTK
VYGGDLGIALTDTYTTEIFFNQFDKKYSKLFDGVRHDSGDPIEFAQKVISHYTKMGIDPKSKVIVFSDSLNYDKVKKIVD
FCQDKIKMSFGIGTNFTNDVGLPAMNMVIKLTDTKPDNIHWQGVVKLSDEKNKNTGTPEMIALAKEVLGIK

Sequences:

>Translated_391_residues
MEATFLKSILDNDFYKFTMQHAVIKLFPKAKVRYGFINRGKHIFPEGFADLLRRSVDALSELRLTKEEKSYLAHYCPYLD
PTYLDFLQGYSFDPSEVQISQEGSEISVTVEGYWYRTILWEVPLMALISELFYKSNHLIRLNDEAIKELTKEKIDNYNKL
GVSILEFGTRRRHSYDVHDLVNETLRTYGGNSFIGTSNVHFAMVNNRRPLGTHAHEWFMFHAAQYGFQVANFISLENWTK
VYGGDLGIALTDTYTTEIFFNQFDKKYSKLFDGVRHDSGDPIEFAQKVISHYTKMGIDPKSKVIVFSDSLNYDKVKKIVD
FCQDKIKMSFGIGTNFTNDVGLPAMNMVIKLTDTKPDNIHWQGVVKLSDEKNKNTGTPEMIALAKEVLGIK
>Mature_391_residues
MEATFLKSILDNDFYKFTMQHAVIKLFPKAKVRYGFINRGKHIFPEGFADLLRRSVDALSELRLTKEEKSYLAHYCPYLD
PTYLDFLQGYSFDPSEVQISQEGSEISVTVEGYWYRTILWEVPLMALISELFYKSNHLIRLNDEAIKELTKEKIDNYNKL
GVSILEFGTRRRHSYDVHDLVNETLRTYGGNSFIGTSNVHFAMVNNRRPLGTHAHEWFMFHAAQYGFQVANFISLENWTK
VYGGDLGIALTDTYTTEIFFNQFDKKYSKLFDGVRHDSGDPIEFAQKVISHYTKMGIDPKSKVIVFSDSLNYDKVKKIVD
FCQDKIKMSFGIGTNFTNDVGLPAMNMVIKLTDTKPDNIHWQGVVKLSDEKNKNTGTPEMIALAKEVLGIK

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=381, Percent_Identity=35.9580052493438, Blast_Score=230, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6324783, Length=423, Percent_Identity=35.9338061465721, Blast_Score=218, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45002; Mature: 45002

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEATFLKSILDNDFYKFTMQHAVIKLFPKAKVRYGFINRGKHIFPEGFADLLRRSVDALS
CCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCCHHHHHHHHHHHHHHH
ELRLTKEEKSYLAHYCPYLDPTYLDFLQGYSFDPSEVQISQEGSEISVTVEGYWYRTILW
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECEEEEHHHH
EVPLMALISELFYKSNHLIRLNDEAIKELTKEKIDNYNKLGVSILEFGTRRRHSYDVHDL
HHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHH
VNETLRTYGGNSFIGTSNVHFAMVNNRRPLGTHAHEWFMFHAAQYGFQVANFISLENWTK
HHHHHHHCCCCCEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYGGDLGIALTDTYTTEIFFNQFDKKYSKLFDGVRHDSGDPIEFAQKVISHYTKMGIDPK
HHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
SKVIVFSDSLNYDKVKKIVDFCQDKIKMSFGIGTNFTNDVGLPAMNMVIKLTDTKPDNIH
CEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCEE
WQGVVKLSDEKNKNTGTPEMIALAKEVLGIK
EEEEEEECCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MEATFLKSILDNDFYKFTMQHAVIKLFPKAKVRYGFINRGKHIFPEGFADLLRRSVDALS
CCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCCHHHHHHHHHHHHHHH
ELRLTKEEKSYLAHYCPYLDPTYLDFLQGYSFDPSEVQISQEGSEISVTVEGYWYRTILW
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECEEEEHHHH
EVPLMALISELFYKSNHLIRLNDEAIKELTKEKIDNYNKLGVSILEFGTRRRHSYDVHDL
HHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHH
VNETLRTYGGNSFIGTSNVHFAMVNNRRPLGTHAHEWFMFHAAQYGFQVANFISLENWTK
HHHHHHHCCCCCEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYGGDLGIALTDTYTTEIFFNQFDKKYSKLFDGVRHDSGDPIEFAQKVISHYTKMGIDPK
HHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
SKVIVFSDSLNYDKVKKIVDFCQDKIKMSFGIGTNFTNDVGLPAMNMVIKLTDTKPDNIH
CEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCEE
WQGVVKLSDEKNKNTGTPEMIALAKEVLGIK
EEEEEEECCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA