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The map label for this gene is pqqL [C]

Identifier: 146300009

GI number: 146300009

Start: 2712737

End: 2715475

Strand: Direct

Name: pqqL [C]

Synonym: Fjoh_2253

Alternate gene names: 146300009

Gene position: 2712737-2715475 (Clockwise)

Preceding gene: 146300008

Following gene: 146300010

Centisome position: 44.49

GC content: 33.3

Gene sequence:

>2739_bases
ATGAAAAACGTATTACTAGGTGGAATTTTATGCTGTACATTAATTTCATTGAGTCCTGTTTATGCCCAAAAAAAGGTCGA
AGTGCCTAAATACATTACCAATATTGAAGGTGTAAAAGAATATTCTTTAAACAACGGATTAAAAATTCTTTTAATTCCAG
ATGCTTCTCAGAGCAATATGATAGTTAATATCGTTTATAATGTAGGTTCCAGAAATGAAGGCTATGGTGAAAAAGGAATG
GCGCATTTGCTGGAACACATGCTTTTTAAGAGTACTAAGAATTTAGGCGATATTAAAAAAATGTTGTCAGACAAAGGAGG
AAATGCAAACGGAACCACCTGGTTAGACAGAACAAACTATTACGAGATTTTTCCATCAAGCGATGAAAACTTAAAATGGA
GCATCGAAATGGAAGCCGACAGAATGATTCATGCTACCATTTTACAGTCAGACCTTGACAAAGAATTCTCTGTAGTTAGA
AATGAGTTTGAAATAGGAGAAAATAATCCTGATGGAGTGTTGCAGGAAAGAATTCTTTCTGCAGCTTATTTGTGGCATAA
TTACGGAAACAGTACCATAGGAAGTAAAGAAGATATTGAAAGAGTAAAAGCAAATACGCTGCGAGTTTTTTATGAAAAAT
ACTATCAGCCGGATAACGCAACTCTTATAATTGCAGGAAAATTTGATGAAAAGAAAGCGCTGCAGTATGCAGGTCAGTAT
TTTGGAGCAATCCCTCGACCAAAAAGAGTTTTAGATAAAACCTATACAATTGAGCCGGCTCAGGATGGAGAAAAATATGT
TGAGCTTAAAAGAGCCGGAGACAGCAAAAATGTTGGAGCTTTGTACCACACAGCATCTTATGCAGATAAAGATTACGCAG
CAATTGATGCGTTAGGCGAAATTTTAACAGCAGATCCATCAGGTTATTTGTATAAATCTTTAGTCGAAACACAAAAAATA
TCCAGTATTTATTTTTGGCAGCCTACAGTAAGAGATGCCGGATTTATTTATTTTGGAGCTGCATTGCCGAATGATAAAGA
TGTAAAAGAAACGAAAGAACTTATTAGAACTGAGCTGGATAAAATTGCATCAACAAAATATACAGATCAGGATATTAGCA
GAGCAAAAGCTAAAATTATTAAGCAGATTGAGGCAGTAAAAAACAATACAATTTCGTATGCTGTAAACATGACAGAAATT
GTTGGAGCCGGAGATTACAGACTTGGTTTTTTATATAGAGATGCAATTGAAAACCTTACAAAAGAAGATGTTCAAAGAGT
AGCCGAGAAATATTTTAAAGCAAATAACAGAACAGTTGGTATTTTTATTCCGTCAAAAGATGAAGTAAGAGTAAAACCAA
ACGAATATACTGATGAGCAATTATCAGCATTAATTAAAGATTACAAAGGAAAAGCACTTGAAAAAGAAGCTGCGCCGTTT
GAAGCCTCTATTAAAAATTTAAAACAAAATTTTGCCGAAGGCAAATTAAGCAACGGCATTAAATACGGATTAATTAAAAA
AGAAATCAAAGGCGGAAAAGTTCAGGCAAGTTTTAGATTTCCGGTGAGCAACGAAAAAGATTTAACAGATAAAAGCGATA
TTGCCGGTATTCTTGCTCAGTTATTAAAAACAGGAACAAAAACACAATCTAAAGAGCAGATCCAGGATCGATTAGATCAA
TTGAAATCTTCAATTAATTTTAATTTTTCGAGACAAACTTTAACTGTCAATATCAATACTTATAAAGAAAATTTTAAGGA
AGTAATGGGAATTTTAGCAGACTTGCTGGCTAATTCAACTTTTCCTGAAAATGAACTTACCAAAACAATCAGTGAGTATA
ATACTTATTTAGAGTCTAGTTTAAACGATCCGCAGGCTGTGGCATTTACTGAAATTACAAGGTCAACAACAAAATATCCA
AAAGGAAATATGTTTTATACACCAACGATTCAGGAACAGATAGATGCTTTCAAAAAAATAAAACAATCAGAAATTGTTGA
TTTTTATAAAAATGTTTTGGGCGGAAATAATGGTGTAGGAAGTGTAGTAGGAGATTTAGATGCTAAAACTACAGGAGAAA
TTTTAGAAAGCACATTTGGAAAATGGAATTCTAAGGCGAAATATGAACTTGCTTTGCCAACTTATTTTGAAACACAAAAA
TTAGACAAAGACATTATTACTCCAGACAAAGAAAATGCGGTTGCTTTAGGAAGAATCAGTTTTAAGATGGATAGAAACAG
TGCTGATTATCCTGCATTTGTTATGGCAAATGAGATGTTAGGAAGCGGTGGTTTCTTAAGTGCCAGAATTCCGATGAGAT
TAAGAGAAAAAGAAGGAATCAGCTATGGTGCAGGCTCTTTTGCAGATATTCCAATTACAAACAATGCGGCTTCATGGAGT
TATTATGCTTTTTTAAATCCAACGAAAAAAGGCGCTGTTGAAACTGCAGCAAAAGAAGAAATTGCAAAAGCAATAAAAGA
TGGATTTACAGCAGAAGAACTAAAATCTAATCTAACCAGCTGGCAAAACGAAAGAAAAACAAGATTAGGAGTTGACGGTA
CATTAATGGAACTGTCAAATAATTATTTACAATACGGAGTGCCTTTAGAAGATTATGATACTTTGGAAACAAAAATCAAA
GCTTTAAAAGTTGAAGATGTAAATAGTGTTTTGAAGAAATATCTTTCATTAGATAAAATGACTTCAGTGTATGCTGGAGA
TTTTAATAAGAAAAACTAA

Upstream 100 bases:

>100_bases
TTTTGTAATTCCTAAATCTTAGTTAATGTAGGTTTTTACTTTAGGAAAAATATTATATTTGGTTATCATTAACAAATTAA
TAACCAATCCATCACAACCT

Downstream 100 bases:

>100_bases
AGAAGGAAAATTTCAATGTAAAAAAAACGAAATGCATTTCACAATGTCATTTCGGTTTTTTTATGCTGTTATTAGGATTT
GAATTTGGGATTTCAAAATT

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 912; Mature: 912

Protein sequence:

>912_residues
MKNVLLGGILCCTLISLSPVYAQKKVEVPKYITNIEGVKEYSLNNGLKILLIPDASQSNMIVNIVYNVGSRNEGYGEKGM
AHLLEHMLFKSTKNLGDIKKMLSDKGGNANGTTWLDRTNYYEIFPSSDENLKWSIEMEADRMIHATILQSDLDKEFSVVR
NEFEIGENNPDGVLQERILSAAYLWHNYGNSTIGSKEDIERVKANTLRVFYEKYYQPDNATLIIAGKFDEKKALQYAGQY
FGAIPRPKRVLDKTYTIEPAQDGEKYVELKRAGDSKNVGALYHTASYADKDYAAIDALGEILTADPSGYLYKSLVETQKI
SSIYFWQPTVRDAGFIYFGAALPNDKDVKETKELIRTELDKIASTKYTDQDISRAKAKIIKQIEAVKNNTISYAVNMTEI
VGAGDYRLGFLYRDAIENLTKEDVQRVAEKYFKANNRTVGIFIPSKDEVRVKPNEYTDEQLSALIKDYKGKALEKEAAPF
EASIKNLKQNFAEGKLSNGIKYGLIKKEIKGGKVQASFRFPVSNEKDLTDKSDIAGILAQLLKTGTKTQSKEQIQDRLDQ
LKSSINFNFSRQTLTVNINTYKENFKEVMGILADLLANSTFPENELTKTISEYNTYLESSLNDPQAVAFTEITRSTTKYP
KGNMFYTPTIQEQIDAFKKIKQSEIVDFYKNVLGGNNGVGSVVGDLDAKTTGEILESTFGKWNSKAKYELALPTYFETQK
LDKDIITPDKENAVALGRISFKMDRNSADYPAFVMANEMLGSGGFLSARIPMRLREKEGISYGAGSFADIPITNNAASWS
YYAFLNPTKKGAVETAAKEEIAKAIKDGFTAEELKSNLTSWQNERKTRLGVDGTLMELSNNYLQYGVPLEDYDTLETKIK
ALKVEDVNSVLKKYLSLDKMTSVYAGDFNKKN

Sequences:

>Translated_912_residues
MKNVLLGGILCCTLISLSPVYAQKKVEVPKYITNIEGVKEYSLNNGLKILLIPDASQSNMIVNIVYNVGSRNEGYGEKGM
AHLLEHMLFKSTKNLGDIKKMLSDKGGNANGTTWLDRTNYYEIFPSSDENLKWSIEMEADRMIHATILQSDLDKEFSVVR
NEFEIGENNPDGVLQERILSAAYLWHNYGNSTIGSKEDIERVKANTLRVFYEKYYQPDNATLIIAGKFDEKKALQYAGQY
FGAIPRPKRVLDKTYTIEPAQDGEKYVELKRAGDSKNVGALYHTASYADKDYAAIDALGEILTADPSGYLYKSLVETQKI
SSIYFWQPTVRDAGFIYFGAALPNDKDVKETKELIRTELDKIASTKYTDQDISRAKAKIIKQIEAVKNNTISYAVNMTEI
VGAGDYRLGFLYRDAIENLTKEDVQRVAEKYFKANNRTVGIFIPSKDEVRVKPNEYTDEQLSALIKDYKGKALEKEAAPF
EASIKNLKQNFAEGKLSNGIKYGLIKKEIKGGKVQASFRFPVSNEKDLTDKSDIAGILAQLLKTGTKTQSKEQIQDRLDQ
LKSSINFNFSRQTLTVNINTYKENFKEVMGILADLLANSTFPENELTKTISEYNTYLESSLNDPQAVAFTEITRSTTKYP
KGNMFYTPTIQEQIDAFKKIKQSEIVDFYKNVLGGNNGVGSVVGDLDAKTTGEILESTFGKWNSKAKYELALPTYFETQK
LDKDIITPDKENAVALGRISFKMDRNSADYPAFVMANEMLGSGGFLSARIPMRLREKEGISYGAGSFADIPITNNAASWS
YYAFLNPTKKGAVETAAKEEIAKAIKDGFTAEELKSNLTSWQNERKTRLGVDGTLMELSNNYLQYGVPLEDYDTLETKIK
ALKVEDVNSVLKKYLSLDKMTSVYAGDFNKKN
>Mature_912_residues
MKNVLLGGILCCTLISLSPVYAQKKVEVPKYITNIEGVKEYSLNNGLKILLIPDASQSNMIVNIVYNVGSRNEGYGEKGM
AHLLEHMLFKSTKNLGDIKKMLSDKGGNANGTTWLDRTNYYEIFPSSDENLKWSIEMEADRMIHATILQSDLDKEFSVVR
NEFEIGENNPDGVLQERILSAAYLWHNYGNSTIGSKEDIERVKANTLRVFYEKYYQPDNATLIIAGKFDEKKALQYAGQY
FGAIPRPKRVLDKTYTIEPAQDGEKYVELKRAGDSKNVGALYHTASYADKDYAAIDALGEILTADPSGYLYKSLVETQKI
SSIYFWQPTVRDAGFIYFGAALPNDKDVKETKELIRTELDKIASTKYTDQDISRAKAKIIKQIEAVKNNTISYAVNMTEI
VGAGDYRLGFLYRDAIENLTKEDVQRVAEKYFKANNRTVGIFIPSKDEVRVKPNEYTDEQLSALIKDYKGKALEKEAAPF
EASIKNLKQNFAEGKLSNGIKYGLIKKEIKGGKVQASFRFPVSNEKDLTDKSDIAGILAQLLKTGTKTQSKEQIQDRLDQ
LKSSINFNFSRQTLTVNINTYKENFKEVMGILADLLANSTFPENELTKTISEYNTYLESSLNDPQAVAFTEITRSTTKYP
KGNMFYTPTIQEQIDAFKKIKQSEIVDFYKNVLGGNNGVGSVVGDLDAKTTGEILESTFGKWNSKAKYELALPTYFETQK
LDKDIITPDKENAVALGRISFKMDRNSADYPAFVMANEMLGSGGFLSARIPMRLREKEGISYGAGSFADIPITNNAASWS
YYAFLNPTKKGAVETAAKEEIAKAIKDGFTAEELKSNLTSWQNERKTRLGVDGTLMELSNNYLQYGVPLEDYDTLETKIK
ALKVEDVNSVLKKYLSLDKMTSVYAGDFNKKN

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=215, Percent_Identity=26.5116279069767, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1787770, Length=223, Percent_Identity=27.3542600896861, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI72001443, Length=236, Percent_Identity=27.1186440677966, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=365, Percent_Identity=24.3835616438356, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21357875, Length=217, Percent_Identity=24.8847926267281, Blast_Score=74, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24646943, Length=217, Percent_Identity=24.8847926267281, Blast_Score=74, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 102349; Mature: 102349

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVLLGGILCCTLISLSPVYAQKKVEVPKYITNIEGVKEYSLNNGLKILLIPDASQSNM
CCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHCCCCHHHHHCCCCCEEEEECCCCCCCE
IVNIVYNVGSRNEGYGEKGMAHLLEHMLFKSTKNLGDIKKMLSDKGGNANGTTWLDRTNY
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEECCCE
YEIFPSSDENLKWSIEMEADRMIHATILQSDLDKEFSVVRNEFEIGENNPDGVLQERILS
EEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AAYLWHNYGNSTIGSKEDIERVKANTLRVFYEKYYQPDNATLIIAGKFDEKKALQYAGQY
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
FGAIPRPKRVLDKTYTIEPAQDGEKYVELKRAGDSKNVGALYHTASYADKDYAAIDALGE
HCCCCCCHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHH
ILTADPSGYLYKSLVETQKISSIYFWQPTVRDAGFIYFGAALPNDKDVKETKELIRTELD
HHCCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
KIASTKYTDQDISRAKAKIIKQIEAVKNNTISYAVNMTEIVGAGDYRLGFLYRDAIENLT
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCEEHHHHHHHHHHHH
KEDVQRVAEKYFKANNRTVGIFIPSKDEVRVKPNEYTDEQLSALIKDYKGKALEKEAAPF
HHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHCCCH
EASIKNLKQNFAEGKLSNGIKYGLIKKEIKGGKVQASFRFPVSNEKDLTDKSDIAGILAQ
HHHHHHHHHHHHCCHHCCCCEEEEEHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
LLKTGTKTQSKEQIQDRLDQLKSSINFNFSRQTLTVNINTYKENFKEVMGILADLLANST
HHHCCCCCCHHHHHHHHHHHHHHHCCCCEECEEEEEEEHHHHHHHHHHHHHHHHHHHCCC
FPENELTKTISEYNTYLESSLNDPQAVAFTEITRSTTKYPKGNMFYTPTIQEQIDAFKKI
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHH
KQSEIVDFYKNVLGGNNGVGSVVGDLDAKTTGEILESTFGKWNSKAKYELALPTYFETQK
HHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHH
LDKDIITPDKENAVALGRISFKMDRNSADYPAFVMANEMLGSGGFLSARIPMRLREKEGI
CCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEHHHHCCCCEEEEECCHHHHHHCCC
SYGAGSFADIPITNNAASWSYYAFLNPTKKGAVETAAKEEIAKAIKDGFTAEELKSNLTS
CCCCCCCEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
WQNERKTRLGVDGTLMELSNNYLQYGVPLEDYDTLETKIKALKVEDVNSVLKKYLSLDKM
HHHHHHHCCCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSVYAGDFNKKN
HHHHCCCCCCCC
>Mature Secondary Structure
MKNVLLGGILCCTLISLSPVYAQKKVEVPKYITNIEGVKEYSLNNGLKILLIPDASQSNM
CCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHCCCCHHHHHCCCCCEEEEECCCCCCCE
IVNIVYNVGSRNEGYGEKGMAHLLEHMLFKSTKNLGDIKKMLSDKGGNANGTTWLDRTNY
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEECCCE
YEIFPSSDENLKWSIEMEADRMIHATILQSDLDKEFSVVRNEFEIGENNPDGVLQERILS
EEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AAYLWHNYGNSTIGSKEDIERVKANTLRVFYEKYYQPDNATLIIAGKFDEKKALQYAGQY
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
FGAIPRPKRVLDKTYTIEPAQDGEKYVELKRAGDSKNVGALYHTASYADKDYAAIDALGE
HCCCCCCHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHH
ILTADPSGYLYKSLVETQKISSIYFWQPTVRDAGFIYFGAALPNDKDVKETKELIRTELD
HHCCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
KIASTKYTDQDISRAKAKIIKQIEAVKNNTISYAVNMTEIVGAGDYRLGFLYRDAIENLT
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCEEHHHHHHHHHHHH
KEDVQRVAEKYFKANNRTVGIFIPSKDEVRVKPNEYTDEQLSALIKDYKGKALEKEAAPF
HHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHCCCH
EASIKNLKQNFAEGKLSNGIKYGLIKKEIKGGKVQASFRFPVSNEKDLTDKSDIAGILAQ
HHHHHHHHHHHHCCHHCCCCEEEEEHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
LLKTGTKTQSKEQIQDRLDQLKSSINFNFSRQTLTVNINTYKENFKEVMGILADLLANST
HHHCCCCCCHHHHHHHHHHHHHHHCCCCEECEEEEEEEHHHHHHHHHHHHHHHHHHHCCC
FPENELTKTISEYNTYLESSLNDPQAVAFTEITRSTTKYPKGNMFYTPTIQEQIDAFKKI
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHH
KQSEIVDFYKNVLGGNNGVGSVVGDLDAKTTGEILESTFGKWNSKAKYELALPTYFETQK
HHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHH
LDKDIITPDKENAVALGRISFKMDRNSADYPAFVMANEMLGSGGFLSARIPMRLREKEGI
CCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEHHHHCCCCEEEEECCHHHHHHCCC
SYGAGSFADIPITNNAASWSYYAFLNPTKKGAVETAAKEEIAKAIKDGFTAEELKSNLTS
CCCCCCCEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
WQNERKTRLGVDGTLMELSNNYLQYGVPLEDYDTLETKIKALKVEDVNSVLKKYLSLDKM
HHHHHHHCCCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSVYAGDFNKKN
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]