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The map label for this gene is engA

Identifier: 146299639

GI number: 146299639

Start: 2164771

End: 2166084

Strand: Direct

Name: engA

Synonym: Fjoh_1879

Alternate gene names: 146299639

Gene position: 2164771-2166084 (Clockwise)

Preceding gene: 146299638

Following gene: 146299640

Centisome position: 35.51

GC content: 37.14

Gene sequence:

>1314_bases
ATGAATAATAACATTGTTGCGATAGTAGGAAGACCTAATGTAGGGAAATCGACCCTTTTTAATAGGCTGATACAAAGAAG
AGAAGCTATTGTAGATTCAGTATCTGGGGTTACCCGTGATAGAAACTATGGTAAAAGCGAGTGGAACGGAAAAGAGTTTT
CTGTCATTGATACGGGAGGATACGTTCGCGGATCTGATGACGTATTTGAAGGTGAAATTCGTAAACAGGTAGAACTTGCT
ATCGACGAAGCCGATGTTATTATTTTTGTGGTTGATGTTGAAGAAGGTATTACACCAATGGATGAAACTGTTGCAAAGTT
ACTTCGTAAAGTAACAAAACCTGTTTTATTGGCTGTAAACAAAGTAGATAACGCTATGCGCGAAAAAGATGCTATAGAAT
TTTATAATCTTGGTTTAGGAGATTATTATACTTTCGCCAGTATCTCAGGAAGCGGAACTGGAGATTTATTAGATGCTTTA
ATTGATGCATTTCCAGAAAAACCAGAACCAGCAGAGGCAGCAGAAGAATTACCTCGTTTTGCTGTGGTAGGACGCCCAAA
TGCAGGAAAATCTAGTTTTATCAACGCCTTAATTGGTCAGGATCGTTATATAGTAACCGATATTGCCGGAACAACACGTG
ATGCGATTGATACAAAATTTGACCGTTTTGGTTTCGAATTCAACTTGGTTGATACTGCGGGAATCCGTCGTAAAGCAAAA
GTAAAAGAAGATTTAGAGTTTTATTCTGTAATGCGTTCTGTAAGAGCAATTGAGCATGCAGATGTTTGTATATTAGTAAT
CGATGCGACACGTGGTTTTGAAGGTCAGGACCAGAGTATTTTCTGGCTTGCAGAGAAAAACCGTAAAGGTGTTGTAATCT
TGGTAAACAAATGGGATTTAGTTGAAAAAGACACCATGTCAAGCCGTGATTACGAAGAGAAAATCCGCAAGGAATTAATG
CCTTTTACAGATGTGCCTATTTTATTCGTTTCGGCTTTAACGAAACAACGTTTATTAAAAGCATTAGAAGCTACGGTTCA
GGTTTTTGAAAACAGAAAGCAAAGAATTTCTACTTCAAAATTCAACGAATATATGCTGAAAGTTATCGAAGCATATCCGC
CGCCGGCAATGAAAGGAAAATATGTAAAAATTAAATATTGCATGCAATTGCCAACGCAGACTCCTCAGTTTGTATTTTTT
GCCAATCTGCCGCAATATGTAAAAGAACCATATAAGAGATATCTGGAAAATAAAATTCGTGATAATTGGGATTTTGCAGG
AGTGCCAATCGATATTTATATCAGAGAGAAATAA

Upstream 100 bases:

>100_bases
TTGCAAAAAATTTAAATAAGGCATTTAGGGTTTTAGTGATCCGGTTTTTAGGCAGCTAAAGATCTGAAATTTAAAGTCTA
AAGTCTAAAATTCAAAAAAA

Downstream 100 bases:

>100_bases
TAAAAAAGAGTCCCCAAAAAAGGGGACTTTTTTTATATGATAATTTTAATGGCACGTTATTTGAATAAATGTAAAAACTA
CAATTAAAAAATAAAATTTT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MNNNIVAIVGRPNVGKSTLFNRLIQRREAIVDSVSGVTRDRNYGKSEWNGKEFSVIDTGGYVRGSDDVFEGEIRKQVELA
IDEADVIIFVVDVEEGITPMDETVAKLLRKVTKPVLLAVNKVDNAMREKDAIEFYNLGLGDYYTFASISGSGTGDLLDAL
IDAFPEKPEPAEAAEELPRFAVVGRPNAGKSSFINALIGQDRYIVTDIAGTTRDAIDTKFDRFGFEFNLVDTAGIRRKAK
VKEDLEFYSVMRSVRAIEHADVCILVIDATRGFEGQDQSIFWLAEKNRKGVVILVNKWDLVEKDTMSSRDYEEKIRKELM
PFTDVPILFVSALTKQRLLKALEATVQVFENRKQRISTSKFNEYMLKVIEAYPPPAMKGKYVKIKYCMQLPTQTPQFVFF
ANLPQYVKEPYKRYLENKIRDNWDFAGVPIDIYIREK

Sequences:

>Translated_437_residues
MNNNIVAIVGRPNVGKSTLFNRLIQRREAIVDSVSGVTRDRNYGKSEWNGKEFSVIDTGGYVRGSDDVFEGEIRKQVELA
IDEADVIIFVVDVEEGITPMDETVAKLLRKVTKPVLLAVNKVDNAMREKDAIEFYNLGLGDYYTFASISGSGTGDLLDAL
IDAFPEKPEPAEAAEELPRFAVVGRPNAGKSSFINALIGQDRYIVTDIAGTTRDAIDTKFDRFGFEFNLVDTAGIRRKAK
VKEDLEFYSVMRSVRAIEHADVCILVIDATRGFEGQDQSIFWLAEKNRKGVVILVNKWDLVEKDTMSSRDYEEKIRKELM
PFTDVPILFVSALTKQRLLKALEATVQVFENRKQRISTSKFNEYMLKVIEAYPPPAMKGKYVKIKYCMQLPTQTPQFVFF
ANLPQYVKEPYKRYLENKIRDNWDFAGVPIDIYIREK
>Mature_437_residues
MNNNIVAIVGRPNVGKSTLFNRLIQRREAIVDSVSGVTRDRNYGKSEWNGKEFSVIDTGGYVRGSDDVFEGEIRKQVELA
IDEADVIIFVVDVEEGITPMDETVAKLLRKVTKPVLLAVNKVDNAMREKDAIEFYNLGLGDYYTFASISGSGTGDLLDAL
IDAFPEKPEPAEAAEELPRFAVVGRPNAGKSSFINALIGQDRYIVTDIAGTTRDAIDTKFDRFGFEFNLVDTAGIRRKAK
VKEDLEFYSVMRSVRAIEHADVCILVIDATRGFEGQDQSIFWLAEKNRKGVVILVNKWDLVEKDTMSSRDYEEKIRKELM
PFTDVPILFVSALTKQRLLKALEATVQVFENRKQRISTSKFNEYMLKVIEAYPPPAMKGKYVKIKYCMQLPTQTPQFVFF
ANLPQYVKEPYKRYLENKIRDNWDFAGVPIDIYIREK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=463, Percent_Identity=37.5809935205184, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=41.304347826087, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788919, Length=129, Percent_Identity=37.984496124031, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=133, Percent_Identity=36.8421052631579, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=197, Percent_Identity=32.994923857868, Blast_Score=93, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_FLAJ1 (A5FIR0)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001194230.1
- ProteinModelPortal:   A5FIR0
- SMR:   A5FIR0
- STRING:   A5FIR0
- GeneID:   5090406
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_1879
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   KCEKAFD
- ProtClustDB:   PRK00093
- BioCyc:   FJOH376686:FJOH_1879-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49688; Mature: 49688

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNIVAIVGRPNVGKSTLFNRLIQRREAIVDSVSGVTRDRNYGKSEWNGKEFSVIDTGG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCC
YVRGSDDVFEGEIRKQVELAIDEADVIIFVVDVEEGITPMDETVAKLLRKVTKPVLLAVN
EECCCCCHHHHHHHHHHHHEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEHHH
KVDNAMREKDAIEFYNLGLGDYYTFASISGSGTGDLLDALIDAFPEKPEPAEAAEELPRF
HHHHHHHHHHCHHHEECCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCE
AVVGRPNAGKSSFINALIGQDRYIVTDIAGTTRDAIDTKFDRFGFEFNLVDTAGIRRKAK
EEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHH
VKEDLEFYSVMRSVRAIEHADVCILVIDATRGFEGQDQSIFWLAEKNRKGVVILVNKWDL
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCEEEEEECCCC
VEKDTMSSRDYEEKIRKELMPFTDVPILFVSALTKQRLLKALEATVQVFENRKQRISTSK
CCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNEYMLKVIEAYPPPAMKGKYVKIKYCMQLPTQTPQFVFFANLPQYVKEPYKRYLENKIR
HHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHC
DNWDFAGVPIDIYIREK
CCCCCCCCEEEEEEECC
>Mature Secondary Structure
MNNNIVAIVGRPNVGKSTLFNRLIQRREAIVDSVSGVTRDRNYGKSEWNGKEFSVIDTGG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCC
YVRGSDDVFEGEIRKQVELAIDEADVIIFVVDVEEGITPMDETVAKLLRKVTKPVLLAVN
EECCCCCHHHHHHHHHHHHEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEHHH
KVDNAMREKDAIEFYNLGLGDYYTFASISGSGTGDLLDALIDAFPEKPEPAEAAEELPRF
HHHHHHHHHHCHHHEECCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCE
AVVGRPNAGKSSFINALIGQDRYIVTDIAGTTRDAIDTKFDRFGFEFNLVDTAGIRRKAK
EEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHH
VKEDLEFYSVMRSVRAIEHADVCILVIDATRGFEGQDQSIFWLAEKNRKGVVILVNKWDL
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCEEEEEECCCC
VEKDTMSSRDYEEKIRKELMPFTDVPILFVSALTKQRLLKALEATVQVFENRKQRISTSK
CCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNEYMLKVIEAYPPPAMKGKYVKIKYCMQLPTQTPQFVFFANLPQYVKEPYKRYLENKIR
HHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHC
DNWDFAGVPIDIYIREK
CCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA