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The map label for this gene is era [H]

Identifier: 146299638

GI number: 146299638

Start: 2163558

End: 2164445

Strand: Direct

Name: era [H]

Synonym: Fjoh_1878

Alternate gene names: 146299638

Gene position: 2163558-2164445 (Clockwise)

Preceding gene: 146299637

Following gene: 146299639

Centisome position: 35.49

GC content: 35.36

Gene sequence:

>888_bases
ATGCAAATGTCACATAAAGCAGGTTTTGTAAACATCATCGGAAATCCAAATGTTGGAAAATCGACACTAATGAACGCCTT
TGTTGGAGAAAGATTATCAATCATAACTTCAAAAGCACAAACAACACGCCATAGAATCTTAGGAATCGTAAATGGCGAAG
ATTTTCAAATAGTACTTTCAGATACTCCCGGAATTATAAAACCGGCTTATGAAATGCAGGAGTCGATGATGAACTTCGTA
AAGTCGGCTTTTGAAGATGCTGATATTTTAGTTTACATGGTCGAAATAGGGGAGCAGAATTTAAAAGACGAAGATTTCTT
TAAAAAAATCTTTTATGCTAAAATCCCGGTTTTACTATTATTAAACAAAATCGACAACTCAAATCAGGAACAATTAGAAG
AGCAGGTTGCTTTTTGGAAAGAAAAAGTGCCAAATGCTGAAATTTTCCCAATTTCGGCACTTCAAAATTTTAATGTCCCG
GAAGTTTTTGAGAGAATTATTCAATTACTGCCAGAATCTCCGGCATATTACCCTAAAGATCAGTTAACAGACAAACCAGA
GCGTTTCTTTGTAAACGAAACGATTCGTGAAAAAATCTTGTTGAATTACGCTAAAGAAATTCCATACGCAGTAGAAATAG
TAACAGAAGAATTTCATGAAACCGATACGATTATCAGAATCCGTTCTGTAATTATGGTAGAACGCGATACGCAAAAAGGA
ATCATTATTGGGCATAAGGGCGCAGCTTTGAAAAAAGTAGGAACAGATGCCCGCGTTGATTTAGAGAAATTCTTCGGAAA
ACAAATTCACATTGAACTTTACGTAAAAGTGAACAAAAACTGGAGAAGCAACGCCAATATGCTGAAACGATTTGGGTATA
ATCAATAG

Upstream 100 bases:

>100_bases
TGCAAAGATACGCCGATTTTTGTGAAATCCAACGAAAACTTTAAAAAATGTTTTATTTTCTGTATTAACTTGATATGACT
ACCTTTGCAAAATAAATAAT

Downstream 100 bases:

>100_bases
GCTTTTGTTTAATCGGTTAATCGTTAATTTGTTTAATCGTTAAATGAAAGTTCTTTTTGAAAATAGGTGCCTTAGCCCTG
ATAGAAGTGGAAATCCTTTT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MQMSHKAGFVNIIGNPNVGKSTLMNAFVGERLSIITSKAQTTRHRILGIVNGEDFQIVLSDTPGIIKPAYEMQESMMNFV
KSAFEDADILVYMVEIGEQNLKDEDFFKKIFYAKIPVLLLLNKIDNSNQEQLEEQVAFWKEKVPNAEIFPISALQNFNVP
EVFERIIQLLPESPAYYPKDQLTDKPERFFVNETIREKILLNYAKEIPYAVEIVTEEFHETDTIIRIRSVIMVERDTQKG
IIIGHKGAALKKVGTDARVDLEKFFGKQIHIELYVKVNKNWRSNANMLKRFGYNQ

Sequences:

>Translated_295_residues
MQMSHKAGFVNIIGNPNVGKSTLMNAFVGERLSIITSKAQTTRHRILGIVNGEDFQIVLSDTPGIIKPAYEMQESMMNFV
KSAFEDADILVYMVEIGEQNLKDEDFFKKIFYAKIPVLLLLNKIDNSNQEQLEEQVAFWKEKVPNAEIFPISALQNFNVP
EVFERIIQLLPESPAYYPKDQLTDKPERFFVNETIREKILLNYAKEIPYAVEIVTEEFHETDTIIRIRSVIMVERDTQKG
IIIGHKGAALKKVGTDARVDLEKFFGKQIHIELYVKVNKNWRSNANMLKRFGYNQ
>Mature_295_residues
MQMSHKAGFVNIIGNPNVGKSTLMNAFVGERLSIITSKAQTTRHRILGIVNGEDFQIVLSDTPGIIKPAYEMQESMMNFV
KSAFEDADILVYMVEIGEQNLKDEDFFKKIFYAKIPVLLLLNKIDNSNQEQLEEQVAFWKEKVPNAEIFPISALQNFNVP
EVFERIIQLLPESPAYYPKDQLTDKPERFFVNETIREKILLNYAKEIPYAVEIVTEEFHETDTIIRIRSVIMVERDTQKG
IIIGHKGAALKKVGTDARVDLEKFFGKQIHIELYVKVNKNWRSNANMLKRFGYNQ

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=323, Percent_Identity=26.625386996904, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1788919, Length=290, Percent_Identity=36.551724137931, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI87082120, Length=179, Percent_Identity=28.4916201117318, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34008; Mature: 34008

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMSHKAGFVNIIGNPNVGKSTLMNAFVGERLSIITSKAQTTRHRILGIVNGEDFQIVLS
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEE
DTPGIIKPAYEMQESMMNFVKSAFEDADILVYMVEIGEQNLKDEDFFKKIFYAKIPVLLL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
LNKIDNSNQEQLEEQVAFWKEKVPNAEIFPISALQNFNVPEVFERIIQLLPESPAYYPKD
HHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHHHHCCCCCCCCCCH
QLTDKPERFFVNETIREKILLNYAKEIPYAVEIVTEEFHETDTIIRIRSVIMVERDTQKG
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHEEECCCCCC
IIIGHKGAALKKVGTDARVDLEKFFGKQIHIELYVKVNKNWRSNANMLKRFGYNQ
EEEECCCCHHHHCCCCCEEEHHHHCCCEEEEEEEEEECCCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MQMSHKAGFVNIIGNPNVGKSTLMNAFVGERLSIITSKAQTTRHRILGIVNGEDFQIVLS
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEE
DTPGIIKPAYEMQESMMNFVKSAFEDADILVYMVEIGEQNLKDEDFFKKIFYAKIPVLLL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
LNKIDNSNQEQLEEQVAFWKEKVPNAEIFPISALQNFNVPEVFERIIQLLPESPAYYPKD
HHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHHHHCCCCCCCCCCH
QLTDKPERFFVNETIREKILLNYAKEIPYAVEIVTEEFHETDTIIRIRSVIMVERDTQKG
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHEEECCCCCC
IIIGHKGAALKKVGTDARVDLEKFFGKQIHIELYVKVNKNWRSNANMLKRFGYNQ
EEEECCCCHHHHCCCCCEEEHHHHCCCEEEEEEEEEECCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA