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The map label for this gene is idnT [H]

Identifier: 146298430

GI number: 146298430

Start: 730272

End: 731591

Strand: Direct

Name: idnT [H]

Synonym: Fjoh_0667

Alternate gene names: 146298430

Gene position: 730272-731591 (Clockwise)

Preceding gene: 146298429

Following gene: 146298431

Centisome position: 11.98

GC content: 37.73

Gene sequence:

>1320_bases
ATGAGCATTTTAATTCTTACGGCATGCATTGCGTTTTTAATCATTCAAATAGCTTGGCTTAAAATCAATCCGTTTATTGC
CTTTATCATAACAGCTTTATTAGCAGGCCTGTTTTTAGGCCTGCCAATAAACACTTTGTCGCAAACTGTTCAAAAAGGTT
TGGGCGAAATGTTAGGATCTATTACGCTGATTATTGTTTTTGGAACCTGTATTGGCAAACTTACCGTTTCATCAGGCGCC
GCCAATGTCATTGCCAAAACAGTTATGGGATGGACGGGCAGAAAATACGTTCGACTCGGCTTAATGATCACCGGATTTAT
TGTTGGGATACCTCTATTTTATAGTGTTGGATTTGTTTTGTTAGTACCACTAATCTTCTCAGTAGCCCATCAGTTCAAAC
TTTCAAAAGTATATCTGGGAATTCCAATGCTGGCGTCGCTTTCAGTAGCACACGGTTTTTTGCCCCCACATCCGTCACCA
ATGGCTTTGAGCAGTATTTTAAATGCTGATATTGGACTTGTTCTGGTTTACGGAATTATAATCGCAGTCCCAACGATTTT
TATTGCCGGTTTATTGTTTTCAAATCTGCTTAAAAACATCAAAACCGAATCAGATCATGAAATTTTAAATGTTGAAGAAG
TAGTAAACCAAGGTAAACTCCCGAGTTTTTCACTTAGTTTATTCTCTGCTTTATTTCCCGTTTTTGGATTAACGCTCACT
TCAATATTACCCATTTACATAAAAAATGAAACGGTAGAAAATATTTGCAAAACGGTAGGAGAACCAAGTATGATTATGCT
GATTTCTTTACTTATCTGTACGTATACTTTAGGACTCAGAATGAACCGAAGCATTACCTCTGTTATGGATGATTATGCAA
CCGCTATAAAAGATGTTGCATTAATTGTTCTAATTGTGGGCGGAGCCGGAGGTTTAAAAGAAGTTATGATTGTAAGCGGA
GTAAACGAAACTATAGTTGGAGCCTTAACACAAATAAACATTCATCCTTATTTATTGGCATGGATAATGGCAGCGATTAT
TCGCGTTTGTGTGGGCTCTGCTACAGCCGCCGGATTAATGACCGCCAGCGTTCTGCTTCCTTTACTGCAAACCACAGGAC
TCGATCCTAACTTATTGGTTTTATCTGTTGGCGCCGGAAGTTTAATGTGCTCACACGTAAACGACCCAAGCTTCTGGATG
TTCAAAGAATATTTTAATATCAGCCTAAAAGACACTTTTAAATCCTGGACCGTCATGGAATCTTTAGTATCTGTTTTAGG
CATCATTTTCGTTTTTATTTTAAACTCTATAATACATTAA

Upstream 100 bases:

>100_bases
GGCTTTTTTAAACTCCTGCTTCAAGTAAAGAAATCTATGTTACTATGTGTTCAATAAAATTTTCACGAATTACTCTCAAC
GGGTTAATAATAAAAGATAA

Downstream 100 bases:

>100_bases
TATCATGAATTTATTACCTCAAGAAAAATTTGAAACTCTTGGTTTGTCTTTACCGCCGGCGCCTCAGCCTCTGGGCATAT
ACAAACCCTATTTAGTTGAT

Product: gluconate transporter

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: L-Ido transporter; 5-keto-D-gluconate transporter [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSILILTACIAFLIIQIAWLKINPFIAFIITALLAGLFLGLPINTLSQTVQKGLGEMLGSITLIIVFGTCIGKLTVSSGA
ANVIAKTVMGWTGRKYVRLGLMITGFIVGIPLFYSVGFVLLVPLIFSVAHQFKLSKVYLGIPMLASLSVAHGFLPPHPSP
MALSSILNADIGLVLVYGIIIAVPTIFIAGLLFSNLLKNIKTESDHEILNVEEVVNQGKLPSFSLSLFSALFPVFGLTLT
SILPIYIKNETVENICKTVGEPSMIMLISLLICTYTLGLRMNRSITSVMDDYATAIKDVALIVLIVGGAGGLKEVMIVSG
VNETIVGALTQINIHPYLLAWIMAAIIRVCVGSATAAGLMTASVLLPLLQTTGLDPNLLVLSVGAGSLMCSHVNDPSFWM
FKEYFNISLKDTFKSWTVMESLVSVLGIIFVFILNSIIH

Sequences:

>Translated_439_residues
MSILILTACIAFLIIQIAWLKINPFIAFIITALLAGLFLGLPINTLSQTVQKGLGEMLGSITLIIVFGTCIGKLTVSSGA
ANVIAKTVMGWTGRKYVRLGLMITGFIVGIPLFYSVGFVLLVPLIFSVAHQFKLSKVYLGIPMLASLSVAHGFLPPHPSP
MALSSILNADIGLVLVYGIIIAVPTIFIAGLLFSNLLKNIKTESDHEILNVEEVVNQGKLPSFSLSLFSALFPVFGLTLT
SILPIYIKNETVENICKTVGEPSMIMLISLLICTYTLGLRMNRSITSVMDDYATAIKDVALIVLIVGGAGGLKEVMIVSG
VNETIVGALTQINIHPYLLAWIMAAIIRVCVGSATAAGLMTASVLLPLLQTTGLDPNLLVLSVGAGSLMCSHVNDPSFWM
FKEYFNISLKDTFKSWTVMESLVSVLGIIFVFILNSIIH
>Mature_438_residues
SILILTACIAFLIIQIAWLKINPFIAFIITALLAGLFLGLPINTLSQTVQKGLGEMLGSITLIIVFGTCIGKLTVSSGAA
NVIAKTVMGWTGRKYVRLGLMITGFIVGIPLFYSVGFVLLVPLIFSVAHQFKLSKVYLGIPMLASLSVAHGFLPPHPSPM
ALSSILNADIGLVLVYGIIIAVPTIFIAGLLFSNLLKNIKTESDHEILNVEEVVNQGKLPSFSLSLFSALFPVFGLTLTS
ILPIYIKNETVENICKTVGEPSMIMLISLLICTYTLGLRMNRSITSVMDDYATAIKDVALIVLIVGGAGGLKEVMIVSGV
NETIVGALTQINIHPYLLAWIMAAIIRVCVGSATAAGLMTASVLLPLLQTTGLDPNLLVLSVGAGSLMCSHVNDPSFWMF
KEYFNISLKDTFKSWTVMESLVSVLGIIFVFILNSIIH

Specific function: Transports L-idonate, D-gluconate and 5-keto-D- gluconate, from the periplasm across the inner membrane [H]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI1790716, Length=440, Percent_Identity=40, Blast_Score=354, Evalue=7e-99,
Organism=Escherichia coli, GI48994935, Length=439, Percent_Identity=39.4077448747153, Blast_Score=351, Evalue=6e-98,
Organism=Escherichia coli, GI1790776, Length=424, Percent_Identity=35.8490566037736, Blast_Score=295, Evalue=5e-81,
Organism=Escherichia coli, GI2367370, Length=447, Percent_Identity=37.3601789709172, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1788707, Length=440, Percent_Identity=30.2272727272727, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI48994939, Length=433, Percent_Identity=30.0230946882217, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1789097, Length=435, Percent_Identity=28.0459770114943, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47136; Mature: 47004

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILILTACIAFLIIQIAWLKINPFIAFIITALLAGLFLGLPINTLSQTVQKGLGEMLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]