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The map label for this gene is wzb [H]

Identifier: 146282833

GI number: 146282833

Start: 2718068

End: 2718433

Strand: Direct

Name: wzb [H]

Synonym: PST_2492

Alternate gene names: 146282833

Gene position: 2718068-2718433 (Clockwise)

Preceding gene: 146282832

Following gene: 146282834

Centisome position: 59.51

GC content: 59.29

Gene sequence:

>366_bases
TTGATCGTCTGTGTCGGGAACATCTGCCGGAGCCCAACCGCCGAAGCGTTGTTCGCGCACAGACTCAGCGGCCAGGGCCT
GACGATCAGTTCGGCGGGCATTGGCGCACTAGTAGGTAACCCCATGGACAAAACCGCCCATGAAGTACTGCAGGACCACG
GGCTGGAACTCCCCGCCCACTGTGCGCGCCAGGTCGACAGTCACATGCTGCACCAGGCCGACCTGATCCTGGCGATGGAG
AACAGCCACATTCAACACATTCGCCAGATTGCACCCGAGGTCCACGGCAAGACGTTTTTTCATCGGCAAATGGCAGGACA
ACCTGGAAATTCCGGACCCCTACCGCCAATCCAAACCCGCTTTTGA

Upstream 100 bases:

>100_bases
CTAATGACACTGCCCAAAATCTCACATTCGTTCATCACGGGCCGAATCCCGGCGGCTGCGACCTTGCAGCCACGAGGTTG
AACCCATGTTCAAGAACATT

Downstream 100 bases:

>100_bases
ACATGTCCACAATCTCCTGACGAAATCCGTCGAGAGCTGGCTTCCTTACCTGAAATGAAGAAGGAACTTCGATGACAACC
ATGCCCCGCCCAATCTATGA

Product: low molecular weight phosphotyrosine protein phosphatase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MIVCVGNICRSPTAEALFAHRLSGQGLTISSAGIGALVGNPMDKTAHEVLQDHGLELPAHCARQVDSHMLHQADLILAME
NSHIQHIRQIAPEVHGKTFFHRQMAGQPGNSGPLPPIQTRF

Sequences:

>Translated_121_residues
MIVCVGNICRSPTAEALFAHRLSGQGLTISSAGIGALVGNPMDKTAHEVLQDHGLELPAHCARQVDSHMLHQADLILAME
NSHIQHIRQIAPEVHGKTFFHRQMAGQPGNSGPLPPIQTRF
>Mature_121_residues
MIVCVGNICRSPTAEALFAHRLSGQGLTISSAGIGALVGNPMDKTAHEVLQDHGLELPAHCARQVDSHMLHQADLILAME
NSHIQHIRQIAPEVHGKTFFHRQMAGQPGNSGPLPPIQTRF

Specific function: Dephosphorylates wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788375, Length=100, Percent_Identity=49, Blast_Score=96, Evalue=9e-22,
Organism=Escherichia coli, GI87081812, Length=121, Percent_Identity=42.9752066115703, Blast_Score=90, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 13083; Mature: 13083

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVCVGNICRSPTAEALFAHRLSGQGLTISSAGIGALVGNPMDKTAHEVLQDHGLELPAH
CEEEECCCCCCCHHHHHHHHHCCCCCEEECCCCCHHHHCCCCCHHHHHHHHHCCCCCHHH
CARQVDSHMLHQADLILAMENSHIQHIRQIAPEVHGKTFFHRQMAGQPGNSGPLPPIQTR
HHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCC
F
C
>Mature Secondary Structure
MIVCVGNICRSPTAEALFAHRLSGQGLTISSAGIGALVGNPMDKTAHEVLQDHGLELPAH
CEEEECCCCCCCHHHHHHHHHCCCCCEEECCCCCHHHHCCCCCHHHHHHHHHCCCCCHHH
CARQVDSHMLHQADLILAMENSHIQHIRQIAPEVHGKTFFHRQMAGQPGNSGPLPPIQTR
HHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]