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The map label for this gene is 146282565

Identifier: 146282565

GI number: 146282565

Start: 2417756

End: 2419141

Strand: Direct

Name: 146282565

Synonym: PST_2217

Alternate gene names: NA

Gene position: 2417756-2419141 (Clockwise)

Preceding gene: 146282564

Following gene: 146282571

Centisome position: 52.93

GC content: 64.0

Gene sequence:

>1386_bases
TTGATAGAGGCGGTTCGCGTCCATGCGCGACGCCGGCTACCTTCCCGATCAACAGCAGGAGCAGACCATGCTTGGCGACT
ACTCATCGATCAACGATCACCTCGAAACCGCGCGCAAGCACGCCGACCAGGCGGAGACCGAAGCGAAGCCCGAACTCTAT
CGCGAGGCCGTCGACGAACTTGTCGCGGCAATTCGCCTGTTGATGCGCAACAGTACAGAAAAGGACAACTGAGCCCATTC
CATCGCCTCGCCAGCTCCCTGGCGAGGCCTAGCGGGGACCCGCCATCCATGCGCCACGACACTGCGACGGAACCGCCACC
CCTGGCCGAGGGCACCCGCCCTGTCCCGCTGGACGAAACCGCCGACACCGGCACGCTGCTTTGCCCTACCCTGCCACCCG
ACCTGCATTATGTGGACGATGCGCAGCCAGGCATCCGCCGCCGACAGCTGCGTGGAAAGTTCGCCTATTTCGCTCCGAGC
GGCGAGCGCATCCGTGACGAAGAAGAGATTCGCCGGATCAACAAACTGGCGATCCCCCCGGCCTATCGGGACGTCTGGAT
CTGCCCCGACCCGCAAGGGCATCTCCAGGCCACGGGACGCGATGCCCGCGGACGCAAGCAGTATCGTTACCATCCGCGCT
GGCGGGAAATCCGCGACAGCGACAAGTACGAGCGCATGCTGGAGTTCGGCGAAGCCCTGCCCAAGCTGCGCCGCGATCTG
GAAAAGCACCTGGCCCTGCCTGGCATGCCGCGCGACAAGGTCATGGCGCTGGTGGTCACGTTGCTCGAATCGACCCTGAT
TCGCATAGGCAATTCCCGCTACGTCAGGGACAACCGGTCCTACGGTCTGACCACACTGCGCACGCGCCACGTGAACGTTA
GCAGCACCGCGGTCCGCTTCCATTTCCGCGGCAAGAGTGGCGTGGAGCACGAGGTGACGCTGCGCGACCGGCGCCTGGCC
AGGCTCATGCGCCGCTGCATGGAGCTACCGGGCCAGCAGTTGTTCCAGTATCTGGATGAGGATGGCCAACGCCGTGCGGT
CAGCTCCAACGACGTGAATCTCTATTTACGGGAAATGACCGGCCGCGATTTCACCGCCAAGGACTATCGGACCTGGGCCG
GCAGCGCGTTGGCGCTGGAACGGTTGCGCAAGCTCGACGCATCCTCGGCAAGCGTCGCGCGGCAGAACCTGGTGGAAACC
GTCAAGCAGGTCGCGAGCCAGCTGGGCAATACTCCGGCGGTCTGTCGCCAGTGCTATATCCATCCGGCGATTCTGCAAGC
CTTCAGCGATGGGGAGCTGGTCAAGCTACGGGCAGCGCGCAAGCGCAAATGGCTGAGCGCCGAGGAAGTCGCCCTGCTTG
CCTTTCTGCGCAAAGCGGCCGATTGA

Upstream 100 bases:

>100_bases
GCGATGCCCGCGGTGCTCCAATCCGACCTGGTCGAAGGCGCTTTCCACCCGCCGCTCGCGCTGATGCACGGTACGAACCG
CCAGTGCTCCTGCCGGTCAG

Downstream 100 bases:

>100_bases
GCGTCAACTTCGACGCGGTCAGTGCTGATGCAGGGTGACGCGATTGCGCCCTGCCGCCTTGGAGGCATAGAGCGCGGAGT
CCGCCCACTCGATCAGCTGT

Product: DNA topoisomerase, type I, putative

Products: NA

Alternate protein names: DNA poisomerase I; DNA poisomerase Type I; DNA poisomerase IB; Type I poisomerase; DNA poisomerase I Protein; Poisomerase IB; Poisomerase IB-Like Protein; DNA poisomerase I-Like Protein; Viral-Like DNA poisomerase; DNA poisomerase ; Eukaryotic-Like DNA poisomerase I; DNA poisomerasei; -Like DNA poisomerase I; Type I DNA poisomerase

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MIEAVRVHARRRLPSRSTAGADHAWRLLIDQRSPRNRAQARRPGGDRSEARTLSRGRRRTCRGNSPVDAQQYRKGQLSPF
HRLASSLARPSGDPPSMRHDTATEPPPLAEGTRPVPLDETADTGTLLCPTLPPDLHYVDDAQPGIRRRQLRGKFAYFAPS
GERIRDEEEIRRINKLAIPPAYRDVWICPDPQGHLQATGRDARGRKQYRYHPRWREIRDSDKYERMLEFGEALPKLRRDL
EKHLALPGMPRDKVMALVVTLLESTLIRIGNSRYVRDNRSYGLTTLRTRHVNVSSTAVRFHFRGKSGVEHEVTLRDRRLA
RLMRRCMELPGQQLFQYLDEDGQRRAVSSNDVNLYLREMTGRDFTAKDYRTWAGSALALERLRKLDASSASVARQNLVET
VKQVASQLGNTPAVCRQCYIHPAILQAFSDGELVKLRAARKRKWLSAEEVALLAFLRKAAD

Sequences:

>Translated_461_residues
MIEAVRVHARRRLPSRSTAGADHAWRLLIDQRSPRNRAQARRPGGDRSEARTLSRGRRRTCRGNSPVDAQQYRKGQLSPF
HRLASSLARPSGDPPSMRHDTATEPPPLAEGTRPVPLDETADTGTLLCPTLPPDLHYVDDAQPGIRRRQLRGKFAYFAPS
GERIRDEEEIRRINKLAIPPAYRDVWICPDPQGHLQATGRDARGRKQYRYHPRWREIRDSDKYERMLEFGEALPKLRRDL
EKHLALPGMPRDKVMALVVTLLESTLIRIGNSRYVRDNRSYGLTTLRTRHVNVSSTAVRFHFRGKSGVEHEVTLRDRRLA
RLMRRCMELPGQQLFQYLDEDGQRRAVSSNDVNLYLREMTGRDFTAKDYRTWAGSALALERLRKLDASSASVARQNLVET
VKQVASQLGNTPAVCRQCYIHPAILQAFSDGELVKLRAARKRKWLSAEEVALLAFLRKAAD
>Mature_461_residues
MIEAVRVHARRRLPSRSTAGADHAWRLLIDQRSPRNRAQARRPGGDRSEARTLSRGRRRTCRGNSPVDAQQYRKGQLSPF
HRLASSLARPSGDPPSMRHDTATEPPPLAEGTRPVPLDETADTGTLLCPTLPPDLHYVDDAQPGIRRRQLRGKFAYFAPS
GERIRDEEEIRRINKLAIPPAYRDVWICPDPQGHLQATGRDARGRKQYRYHPRWREIRDSDKYERMLEFGEALPKLRRDL
EKHLALPGMPRDKVMALVVTLLESTLIRIGNSRYVRDNRSYGLTTLRTRHVNVSSTAVRFHFRGKSGVEHEVTLRDRRLA
RLMRRCMELPGQQLFQYLDEDGQRRAVSSNDVNLYLREMTGRDFTAKDYRTWAGSALALERLRKLDASSASVARQNLVET
VKQVASQLGNTPAVCRQCYIHPAILQAFSDGELVKLRAARKRKWLSAEEVALLAFLRKAAD

Specific function: Unknown

COG id: COG3569

COG function: function code L; Topoisomerase IB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52696; Mature: 52696

Theoretical pI: Translated: 11.09; Mature: 11.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEAVRVHARRRLPSRSTAGADHAWRLLIDQRSPRNRAQARRPGGDRSEARTLSRGRRRT
CCCHHHHHHHHCCCCCCCCCCCHHEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHC
CRGNSPVDAQQYRKGQLSPFHRLASSLARPSGDPPSMRHDTATEPPPLAEGTRPVPLDET
CCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ADTGTLLCPTLPPDLHYVDDAQPGIRRRQLRGKFAYFAPSGERIRDEEEIRRINKLAIPP
CCCCEEECCCCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCCC
AYRDVWICPDPQGHLQATGRDARGRKQYRYHPRWREIRDSDKYERMLEFGEALPKLRRDL
CCCCEEECCCCCCCCEECCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EKHLALPGMPRDKVMALVVTLLESTLIRIGNSRYVRDNRSYGLTTLRTRHVNVSSTAVRF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEECCCCEEEEE
HFRGKSGVEHEVTLRDRRLARLMRRCMELPGQQLFQYLDEDGQRRAVSSNDVNLYLREMT
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECC
GRDFTAKDYRTWAGSALALERLRKLDASSASVARQNLVETVKQVASQLGNTPAVCRQCYI
CCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
HPAILQAFSDGELVKLRAARKRKWLSAEEVALLAFLRKAAD
CHHHHHHCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIEAVRVHARRRLPSRSTAGADHAWRLLIDQRSPRNRAQARRPGGDRSEARTLSRGRRRT
CCCHHHHHHHHCCCCCCCCCCCHHEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHC
CRGNSPVDAQQYRKGQLSPFHRLASSLARPSGDPPSMRHDTATEPPPLAEGTRPVPLDET
CCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ADTGTLLCPTLPPDLHYVDDAQPGIRRRQLRGKFAYFAPSGERIRDEEEIRRINKLAIPP
CCCCEEECCCCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCCC
AYRDVWICPDPQGHLQATGRDARGRKQYRYHPRWREIRDSDKYERMLEFGEALPKLRRDL
CCCCEEECCCCCCCCEECCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EKHLALPGMPRDKVMALVVTLLESTLIRIGNSRYVRDNRSYGLTTLRTRHVNVSSTAVRF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEECCCCEEEEE
HFRGKSGVEHEVTLRDRRLARLMRRCMELPGQQLFQYLDEDGQRRAVSSNDVNLYLREMT
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECC
GRDFTAKDYRTWAGSALALERLRKLDASSASVARQNLVETVKQVASQLGNTPAVCRQCYI
CCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
HPAILQAFSDGELVKLRAARKRKWLSAEEVALLAFLRKAAD
CHHHHHHCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA