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The map label for this gene is metH [H]

Identifier: 146282571

GI number: 146282571

Start: 2425739

End: 2429431

Strand: Direct

Name: metH [H]

Synonym: PST_2223

Alternate gene names: 146282571

Gene position: 2425739-2429431 (Clockwise)

Preceding gene: 146282565

Following gene: 146282572

Centisome position: 53.11

GC content: 63.88

Gene sequence:

>3693_bases
ATGTCCGCTCGCAACGCCCGACTTCAGGCCCTCCAGCACGCGCTCAGCCAGCGCATCCTGATTCTCGACGGTGGTATGGG
AACCATGATCCAGAGCTACAAGCTGGAGGAGTCCGACTACCGGGGCGAGCGATTCACCGATTGGCCGAGCGACGTGAAGG
GCAATAACGACCTGTTGCTGCTCTCCCGCCCCGACGTCATCCAGGCCATCGAGAAGGCCTATCTCGATGCCGGCGCCGAC
ATACTGGAAACCAACACCTTCAATGCCACTCGGGTCTCCCAGGCCGACTACGGCATGGAAGAACTGGTCTACGAGCTGAA
CGTGGAAGGTGCGCGCCTGGCCCGGGAAGTGGCCGATGCCAAGACCGCCGAGACGCCGGATCGCCCGCGTTTCGTCGCCG
GCGTGCTCGGCCCGACCAGCCGCACCTGCTCCATCTCGCCGGACGTCAATAACCCCGGCTACCGCAACGTCACCTTCGAC
CTGCTGGTGGAGAACTACACCGAAGCCACCCGTGGCCTGATCGAGGGCGGCGCTGACCTGATTCTGATCGAAACGATCTT
CGACACGCTGAACGCCAAGGCGGCGATCTTCGCCGTGCAGCAGGTATTCGAGGAAGATGGCGTCGAGCTGCCGATCATGA
TCTCCGGCACCATCACCGATGCCTCCGGCCGCACGCTGTCAGGCCAGACCACCGAGGCGTTCTGGAACTCGGTGCGCCAT
GCCAAGCCGATCTCCGTAGGTCTGAACTGCGCCCTGGGCGCCAAGGACCTGCGCCCTTATCTGGAAGAGCTGGCCAACAA
GGCCGACACCCACGTGTCCGCCCACCCCAACGCCGGCCTGCCCAATGCCTTCGGCGAGTACGACGAAACGCCGGCAGAAA
TGGCCGCGGTGGTCGAGGAGTTCGCCGCCAGCGGTTTCCTCAACATCATCGGCGGCTGCTGCGGCACCACGCCGGCACAC
ATCCAGGCGATTGCAGAGGCGGTGGCCAAGTACCCGCCGCGCGTGATTCCGGACATTCCCAAGGCCTGCCGCCTGTCGGG
CCTGGAGCCCTTCACCATCGACCGCAGCTCGCTGTTCGTCAACGTCGGCGAGCGCACCAACATCACCGGTTCGGCCAAGT
TCGCCCGTCTGATCCGCGAGGAGAACTACACCGAGGCGCTGGAAGTGGCCCTGCAGCAGGTGGAAGCCGGCGCCCAGGTG
ATCGACATCAACATGGACGAGGGCATGCTGGATTCGAAGGCGGCCATGGTCACCTTCCTCAACCTGATCGCCGGCGAGCC
GGACATCTCCCGCGTGCCGATCATGATCGACTCCTCCAAGTGGGAAGTGATCGAGGCGGGCCTCAAGTGCATCCAGGGCA
AGGGCATCGTCAACTCCATCTCCATGAAGGAAGGTGTCGAGCAGTTCAAGCACCACGCCCACCTGTGCAAGCGCTACGGC
GCCGCGGTGGTGGTGATGGCCTTCGACGAAGCCGGCCAGGCCGATACCGCTGCACGCAAGCGCGAAATCTGCCAGCGCAG
CTACGACATCCTGGTCAACGAGGTGGGCTTCCCGCCGGAAGACATCATCTTCGACCCGAACATCTTCGCCATCGCCACCG
GCATCGAAGAGCACAACAACTACGCCGTCGACTTCATCGAAGCCTGCGCCTTCATTCGCGACAACCTGCCCTATGCCCTG
ACCTCGGGCGGCGTGTCCAACGTGTCCTTCTCCTTCCGCGGCAACAACCCGGTGCGCGAAGCGATCCACTCGGTGTTCCT
GTTCCATGCGATCAAGGCGGGCCTGACCATGGGCATCGTCAACGCCGGCCAATTGGAGATCTACGACGAGATCCCGAAGG
AGCTGCGCGACGCGGTCGAGGACGTGGTGCTCAACCGCTGCGCCGGCGGCACCGAGGCGCTGCTTGAGATCGCCGACAAG
TACAAGGGCGATGGCTCGGTCAAGGAAGCCGAGACCGAGGAATGGCGCAATCTGCCGGTGGACAAGCGCCTCGAGCACGC
GCTGGTCAAGGGCATCACCGCCTTCATCGTGGAGGACACCGAGGAGTGCCGCCAGCAGTGCGCACGCCCCATCGAGGTGA
TCGAAGGCCCGCTGATGAGCGGCATGAACGTGGTGGGCGATCTGTTCGGCGCGGGCAAGATGTTCCTGCCCCAGGTGGTC
AAGTCCGCCCGCGTGATGAAGCAGGCCGTGGCACACCTGATCCCCTTCATCGAGGCGGAAAAGGGCGGCAAGCCGGAAGC
CAAGGGCAAGATCCTCATGGCGACCGTCAAGGGCGACGTACACGACATCGGCAAGAACATCGTCGGCGTGGTGCTGGGCT
GCAACGGCTACGACGTGGTGGACATGGGCGTGATGGTGCCGGCGGAAAAGATCCTGCAGACCGCCATCGCCGAGAAGTGC
GACATCATCGGCCTCTCCGGGCTGATCACCCCCTCCTTGGACGAAATGGTTCATGTGGCCAAGGAAATGCAGCGCCAGGG
CTTCAGCCTGCCGCTGATGATCGGCGGCGCCACCACCTCCAAGGCGCACACCGCGGTGAAGATCGACCCGCAGTACAGCA
ACGATGCAGTGGTCTATGTCACCGATGCATCGCGTGCAGTCGGCGTGGCCACCACCCTGCTGTCCAAGGAACTCAAGCCG
GCGTTCGTCGACAAGACCCGCGAAGAGTACGCGATGATCCGCGAGCGCACCGCCAACCGCAGTGCGCGCACCGAACGCCT
GAGCTACCTCGATGCCATCGCCAACAAGCCGCCGTTCGACTGGAGCGGCTACGCCCCGGTCAAACCGAGCTTCACCGGCC
GCCAGGTGCTGGAAGACATCGATCTGCGCACCCTGGTCGACTACATCGACTGGACGCCTTTCTTCATCGCCTGGGACCTG
GCCGGCAAGTATCCGCGCATCCTCGAAGACGAGGTGGTTGGCGAAGCGGCCACCTCGCTGTTCAACGATGCCCAGGCCAT
GCTGAAAAAGCTGGTCGACGAGAAGCTGATCCGCGCACGTGCGGTGTTCGGCTTCTGGCCGGCCAACCAGGTCCAGGACG
ATGACCTGGAAGTGTACGGTGACAACGGCGAGAAGCTGGCCACCCTGCATCACCTGCGCCAGCAGACCATCAAGGCGGAC
GCCAAGCCGAACCTGTCGCTGGCCGACTTCGTGGCACCCAAGAGCACCGGCATCACCGACTACGTGGGCGGTTTCATCTG
CACCGCTGGCATCGGTGCCGAGGAACTGGCCAAGGCCTATCAGGACAAGGGCGACGACTACAACTCGATCATGGTCAAGG
CATTGGCCGACCGCCTCGCCGAGGCCTGTGCCGAATGGCTGCACGAGCAGGTGCGCAAGCACTACTGGGGCTATGCGCCT
GACGAGCGGCTGAGTAACGAGGAACTGATCCGCGAGCAGTACAAGGGCATCCGCCCTGCCCCCGGTTACCCGGCCTGCCC
GGACCACACCGAGAAGGGCACGCTGTTCCAGCTGCTGGATGCCGACGGCATCAGCCAGGTCACCCTCACCGAGCACTACG
CCATGCTGCCCACCGCGGCGGTCAGCGGCTGGTACTTCGCCCATCCCGAGGCGCAGTATTTCGCCGTCGGCAAGATCGAC
AAGGATCAGGTGGAAAGCTACAGCCAGCGCAAGGGCCAGGAATTGGCCATCAGTGAGCGCTGGCTGATGCCGAACCTGGG
CTACGACAACTGA

Upstream 100 bases:

>100_bases
CCAACCTGAATAATCTTCATGCAAATGCGCGACAGCTAAAAAAGCATGCAGCTTTGCTATCATTCGCGCTCTTTTCGTTC
CCGCTTTTCAGGTAGTTCCC

Downstream 100 bases:

>100_bases
TCTCGACGCGGGCGTCTCCCGACGCCTGCGTTCGATCCACGGAGCAAGTGCACCATGTCATCGGAAACACCCTGGCTGAT
CGACGAACTCGAAAATGCCG

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1230; Mature: 1229

Protein sequence:

>1230_residues
MSARNARLQALQHALSQRILILDGGMGTMIQSYKLEESDYRGERFTDWPSDVKGNNDLLLLSRPDVIQAIEKAYLDAGAD
ILETNTFNATRVSQADYGMEELVYELNVEGARLAREVADAKTAETPDRPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFD
LLVENYTEATRGLIEGGADLILIETIFDTLNAKAAIFAVQQVFEEDGVELPIMISGTITDASGRTLSGQTTEAFWNSVRH
AKPISVGLNCALGAKDLRPYLEELANKADTHVSAHPNAGLPNAFGEYDETPAEMAAVVEEFAASGFLNIIGGCCGTTPAH
IQAIAEAVAKYPPRVIPDIPKACRLSGLEPFTIDRSSLFVNVGERTNITGSAKFARLIREENYTEALEVALQQVEAGAQV
IDINMDEGMLDSKAAMVTFLNLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFKHHAHLCKRYG
AAVVVMAFDEAGQADTAARKREICQRSYDILVNEVGFPPEDIIFDPNIFAIATGIEEHNNYAVDFIEACAFIRDNLPYAL
TSGGVSNVSFSFRGNNPVREAIHSVFLFHAIKAGLTMGIVNAGQLEIYDEIPKELRDAVEDVVLNRCAGGTEALLEIADK
YKGDGSVKEAETEEWRNLPVDKRLEHALVKGITAFIVEDTEECRQQCARPIEVIEGPLMSGMNVVGDLFGAGKMFLPQVV
KSARVMKQAVAHLIPFIEAEKGGKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDVVDMGVMVPAEKILQTAIAEKC
DIIGLSGLITPSLDEMVHVAKEMQRQGFSLPLMIGGATTSKAHTAVKIDPQYSNDAVVYVTDASRAVGVATTLLSKELKP
AFVDKTREEYAMIRERTANRSARTERLSYLDAIANKPPFDWSGYAPVKPSFTGRQVLEDIDLRTLVDYIDWTPFFIAWDL
AGKYPRILEDEVVGEAATSLFNDAQAMLKKLVDEKLIRARAVFGFWPANQVQDDDLEVYGDNGEKLATLHHLRQQTIKAD
AKPNLSLADFVAPKSTGITDYVGGFICTAGIGAEELAKAYQDKGDDYNSIMVKALADRLAEACAEWLHEQVRKHYWGYAP
DERLSNEELIREQYKGIRPAPGYPACPDHTEKGTLFQLLDADGISQVTLTEHYAMLPTAAVSGWYFAHPEAQYFAVGKID
KDQVESYSQRKGQELAISERWLMPNLGYDN

Sequences:

>Translated_1230_residues
MSARNARLQALQHALSQRILILDGGMGTMIQSYKLEESDYRGERFTDWPSDVKGNNDLLLLSRPDVIQAIEKAYLDAGAD
ILETNTFNATRVSQADYGMEELVYELNVEGARLAREVADAKTAETPDRPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFD
LLVENYTEATRGLIEGGADLILIETIFDTLNAKAAIFAVQQVFEEDGVELPIMISGTITDASGRTLSGQTTEAFWNSVRH
AKPISVGLNCALGAKDLRPYLEELANKADTHVSAHPNAGLPNAFGEYDETPAEMAAVVEEFAASGFLNIIGGCCGTTPAH
IQAIAEAVAKYPPRVIPDIPKACRLSGLEPFTIDRSSLFVNVGERTNITGSAKFARLIREENYTEALEVALQQVEAGAQV
IDINMDEGMLDSKAAMVTFLNLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFKHHAHLCKRYG
AAVVVMAFDEAGQADTAARKREICQRSYDILVNEVGFPPEDIIFDPNIFAIATGIEEHNNYAVDFIEACAFIRDNLPYAL
TSGGVSNVSFSFRGNNPVREAIHSVFLFHAIKAGLTMGIVNAGQLEIYDEIPKELRDAVEDVVLNRCAGGTEALLEIADK
YKGDGSVKEAETEEWRNLPVDKRLEHALVKGITAFIVEDTEECRQQCARPIEVIEGPLMSGMNVVGDLFGAGKMFLPQVV
KSARVMKQAVAHLIPFIEAEKGGKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDVVDMGVMVPAEKILQTAIAEKC
DIIGLSGLITPSLDEMVHVAKEMQRQGFSLPLMIGGATTSKAHTAVKIDPQYSNDAVVYVTDASRAVGVATTLLSKELKP
AFVDKTREEYAMIRERTANRSARTERLSYLDAIANKPPFDWSGYAPVKPSFTGRQVLEDIDLRTLVDYIDWTPFFIAWDL
AGKYPRILEDEVVGEAATSLFNDAQAMLKKLVDEKLIRARAVFGFWPANQVQDDDLEVYGDNGEKLATLHHLRQQTIKAD
AKPNLSLADFVAPKSTGITDYVGGFICTAGIGAEELAKAYQDKGDDYNSIMVKALADRLAEACAEWLHEQVRKHYWGYAP
DERLSNEELIREQYKGIRPAPGYPACPDHTEKGTLFQLLDADGISQVTLTEHYAMLPTAAVSGWYFAHPEAQYFAVGKID
KDQVESYSQRKGQELAISERWLMPNLGYDN
>Mature_1229_residues
SARNARLQALQHALSQRILILDGGMGTMIQSYKLEESDYRGERFTDWPSDVKGNNDLLLLSRPDVIQAIEKAYLDAGADI
LETNTFNATRVSQADYGMEELVYELNVEGARLAREVADAKTAETPDRPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFDL
LVENYTEATRGLIEGGADLILIETIFDTLNAKAAIFAVQQVFEEDGVELPIMISGTITDASGRTLSGQTTEAFWNSVRHA
KPISVGLNCALGAKDLRPYLEELANKADTHVSAHPNAGLPNAFGEYDETPAEMAAVVEEFAASGFLNIIGGCCGTTPAHI
QAIAEAVAKYPPRVIPDIPKACRLSGLEPFTIDRSSLFVNVGERTNITGSAKFARLIREENYTEALEVALQQVEAGAQVI
DINMDEGMLDSKAAMVTFLNLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFKHHAHLCKRYGA
AVVVMAFDEAGQADTAARKREICQRSYDILVNEVGFPPEDIIFDPNIFAIATGIEEHNNYAVDFIEACAFIRDNLPYALT
SGGVSNVSFSFRGNNPVREAIHSVFLFHAIKAGLTMGIVNAGQLEIYDEIPKELRDAVEDVVLNRCAGGTEALLEIADKY
KGDGSVKEAETEEWRNLPVDKRLEHALVKGITAFIVEDTEECRQQCARPIEVIEGPLMSGMNVVGDLFGAGKMFLPQVVK
SARVMKQAVAHLIPFIEAEKGGKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDVVDMGVMVPAEKILQTAIAEKCD
IIGLSGLITPSLDEMVHVAKEMQRQGFSLPLMIGGATTSKAHTAVKIDPQYSNDAVVYVTDASRAVGVATTLLSKELKPA
FVDKTREEYAMIRERTANRSARTERLSYLDAIANKPPFDWSGYAPVKPSFTGRQVLEDIDLRTLVDYIDWTPFFIAWDLA
GKYPRILEDEVVGEAATSLFNDAQAMLKKLVDEKLIRARAVFGFWPANQVQDDDLEVYGDNGEKLATLHHLRQQTIKADA
KPNLSLADFVAPKSTGITDYVGGFICTAGIGAEELAKAYQDKGDDYNSIMVKALADRLAEACAEWLHEQVRKHYWGYAPD
ERLSNEELIREQYKGIRPAPGYPACPDHTEKGTLFQLLDADGISQVTLTEHYAMLPTAAVSGWYFAHPEAQYFAVGKIDK
DQVESYSQRKGQELAISERWLMPNLGYDN

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1244, Percent_Identity=55.7877813504823, Blast_Score=1350, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1229, Percent_Identity=66.4768104149715, Blast_Score=1653, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535405, Length=1250, Percent_Identity=54.72, Blast_Score=1336, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 134794; Mature: 134663

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARNARLQALQHALSQRILILDGGMGTMIQSYKLEESDYRGERFTDWPSDVKGNNDLLL
CCCCHHHHHHHHHHHHCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEE
LSRPDVIQAIEKAYLDAGADILETNTFNATRVSQADYGMEELVYELNVEGARLAREVADA
EECCHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHC
KTAETPDRPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFDLLVENYTEATRGLIEGGADL
CCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCE
ILIETIFDTLNAKAAIFAVQQVFEEDGVELPIMISGTITDASGRTLSGQTTEAFWNSVRH
EEHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCEECCCHHHHHHHHHHC
AKPISVGLNCALGAKDLRPYLEELANKADTHVSAHPNAGLPNAFGEYDETPAEMAAVVEE
CCCCEECCEEECCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHH
FAASGFLNIIGGCCGTTPAHIQAIAEAVAKYPPRVIPDIPKACRLSGLEPFTIDRSSLFV
HHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEECCCEEEE
NVGERTNITGSAKFARLIREENYTEALEVALQQVEAGAQVIDINMDEGMLDSKAAMVTFL
ECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHH
NLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFKHHAHLCKRYG
HHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AAVVVMAFDEAGQADTAARKREICQRSYDILVNEVGFPPEDIIFDPNIFAIATGIEEHNN
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCEEEEEECHHHCCC
YAVDFIEACAFIRDNLPYALTSGGVSNVSFSFRGNNPVREAIHSVFLFHAIKAGLTMGIV
HHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEC
NAGQLEIYDEIPKELRDAVEDVVLNRCAGGTEALLEIADKYKGDGSVKEAETEEWRNLPV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCH
DKRLEHALVKGITAFIVEDTEECRQQCARPIEVIEGPLMSGMNVVGDLFGAGKMFLPQVV
HHHHHHHHHHHHHHHEECCHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHH
KSARVMKQAVAHLIPFIEAEKGGKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDVV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHCCHHEEEEECCCCCCEE
DMGVMVPAEKILQTAIAEKCDIIGLSGLITPSLDEMVHVAKEMQRQGFSLPLMIGGATTS
CCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
KAHTAVKIDPQYSNDAVVYVTDASRAVGVATTLLSKELKPAFVDKTREEYAMIRERTANR
CCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
SARTERLSYLDAIANKPPFDWSGYAPVKPSFTGRQVLEDIDLRTLVDYIDWTPFFIAWDL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
AGKYPRILEDEVVGEAATSLFNDAQAMLKKLVDEKLIRARAVFGFWPANQVQDDDLEVYG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEC
DNGEKLATLHHLRQQTIKADAKPNLSLADFVAPKSTGITDYVGGFICTAGIGAEELAKAY
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
QDKGDDYNSIMVKALADRLAEACAEWLHEQVRKHYWGYAPDERLSNEELIREQYKGIRPA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHCCCCCC
PGYPACPDHTEKGTLFQLLDADGISQVTLTEHYAMLPTAAVSGWYFAHPEAQYFAVGKID
CCCCCCCCCCCCCCEEEEECCCCCCEEEHHHHHHHCCHHHHCCEEEECCCCCEEEECCCC
KDQVESYSQRKGQELAISERWLMPNLGYDN
HHHHHHHHHHCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SARNARLQALQHALSQRILILDGGMGTMIQSYKLEESDYRGERFTDWPSDVKGNNDLLL
CCCHHHHHHHHHHHHCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEE
LSRPDVIQAIEKAYLDAGADILETNTFNATRVSQADYGMEELVYELNVEGARLAREVADA
EECCHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHC
KTAETPDRPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFDLLVENYTEATRGLIEGGADL
CCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCE
ILIETIFDTLNAKAAIFAVQQVFEEDGVELPIMISGTITDASGRTLSGQTTEAFWNSVRH
EEHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCEECCCHHHHHHHHHHC
AKPISVGLNCALGAKDLRPYLEELANKADTHVSAHPNAGLPNAFGEYDETPAEMAAVVEE
CCCCEECCEEECCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHH
FAASGFLNIIGGCCGTTPAHIQAIAEAVAKYPPRVIPDIPKACRLSGLEPFTIDRSSLFV
HHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEECCCEEEE
NVGERTNITGSAKFARLIREENYTEALEVALQQVEAGAQVIDINMDEGMLDSKAAMVTFL
ECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHH
NLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFKHHAHLCKRYG
HHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AAVVVMAFDEAGQADTAARKREICQRSYDILVNEVGFPPEDIIFDPNIFAIATGIEEHNN
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCEEEEEECHHHCCC
YAVDFIEACAFIRDNLPYALTSGGVSNVSFSFRGNNPVREAIHSVFLFHAIKAGLTMGIV
HHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEC
NAGQLEIYDEIPKELRDAVEDVVLNRCAGGTEALLEIADKYKGDGSVKEAETEEWRNLPV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCH
DKRLEHALVKGITAFIVEDTEECRQQCARPIEVIEGPLMSGMNVVGDLFGAGKMFLPQVV
HHHHHHHHHHHHHHHEECCHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHH
KSARVMKQAVAHLIPFIEAEKGGKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDVV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHCCHHEEEEECCCCCCEE
DMGVMVPAEKILQTAIAEKCDIIGLSGLITPSLDEMVHVAKEMQRQGFSLPLMIGGATTS
CCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
KAHTAVKIDPQYSNDAVVYVTDASRAVGVATTLLSKELKPAFVDKTREEYAMIRERTANR
CCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
SARTERLSYLDAIANKPPFDWSGYAPVKPSFTGRQVLEDIDLRTLVDYIDWTPFFIAWDL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
AGKYPRILEDEVVGEAATSLFNDAQAMLKKLVDEKLIRARAVFGFWPANQVQDDDLEVYG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEC
DNGEKLATLHHLRQQTIKADAKPNLSLADFVAPKSTGITDYVGGFICTAGIGAEELAKAY
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
QDKGDDYNSIMVKALADRLAEACAEWLHEQVRKHYWGYAPDERLSNEELIREQYKGIRPA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHCCCCCC
PGYPACPDHTEKGTLFQLLDADGISQVTLTEHYAMLPTAAVSGWYFAHPEAQYFAVGKID
CCCCCCCCCCCCCCEEEEECCCCCCEEEHHHHHHHCCHHHHCCEEEECCCCCEEEECCCC
KDQVESYSQRKGQELAISERWLMPNLGYDN
HHHHHHHHHHCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]