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The map label for this gene is gpmI

Identifier: 145300952

GI number: 145300952

Start: 4391237

End: 4392766

Strand: Direct

Name: gpmI

Synonym: ASA_4104

Alternate gene names: 145300952

Gene position: 4391237-4392766 (Clockwise)

Preceding gene: 145300948

Following gene: 145300953

Centisome position: 93.38

GC content: 60.98

Gene sequence:

>1530_bases
ATGTCAACAGCTAAGAAACCTTTGGTTCTGGTCATCATGGACGGTTGGGGCTACAGCACCAAGCAAGAGCACAACGCCGT
CGCTGCCGCCAAAACTCCCAACCTCGACCGTCTCGCCCGTGACTACACCAGCACCCTGATCTCCGGCTCCGGCCTGGATG
TGGGTCTGCCGGATGGTCAGATGGGTAACTCCGAAGTGGGCCACGTCAACATAGGTGCCGGTCGCATCGTCTATCAGGAG
CTGACCCGTATCTCCAAAGAGATCAAGGACGGCGACTTCTTCCAGAACGTCGAACTGGCCAAGGCTCTCGATTCTGCCGT
GACCAAGGGCAAAGCCGTTCACATCATGGGTCTGATGTCCCCGGGTGGCGTACACAGCCACGAAGAGCACATCATGGGCA
TGATCGAGATGGCCGCCAAGCGTGGCGCCGAGCAGATCTACTTCCACGCCTTCCTGGATGGCCGCGACGTTCCGCCGCGC
TCCGCCCAGTCCTCCATCGAACAGTTCGATGCCCTGTTTGCCCGTCTGGGCAAGGGTCGTTTCGCCTCCATGATCGGCCG
CTACTTCGCCATGGATCGTGACAACCGCTGGGATCGCGTGCAGCAAGCTTATGACCTGATGACTCAGGGCAAGGGCGAGT
TCACCGCCGACAGCGCCAGCGAAGCCCTGGCCGCCGCCTATGCCCGCGACGAGAACGACGAGTTCGTCAAGGCCACCCGC
ATCGGTGCTGCCGCCCCCATGCAGGATGGCGATGCCCTGATCTTCATGAACTTCCGTGCCGACCGCGCCCGTGAAATCAC
CCGCGCCTTCGTTGACAGTGACTTCACCGGCTTTGCCCGTGCCGCCACCCCTGCGCTGAACTTCGTGATGCTGACCGAAT
ACGCGGCCGACATCAAAACTGCCTGTGCCTACCCGCCGACTGCCCTGGTGAACACCCTGGGTGAGTGGCTGGCCAAGCAG
GGCAAGACCCAGCTGCGCATCTCCGAAACCGAGAAGTACGCCCACGTCACCTTCTTCTTCAACGGTGGCGAAGAGTCCTG
CTTCACCGGTGAAGACCGCGAGATCGTTGCCAGCCCGAAAGTGGCGACTTATGACCTGCAGCCGGAAATGAGCTCCGAAG
AGCTGACCGACAAGCTGGTCGCTGCCATCAAGAGTGGCAAGTACGACACCATCATCTGCAACTACCCGAACGGCGACATG
GTCGGCCACACCGGCGTATTCGATGCGGCCGTCAAAGCCTGTGAAGCCGTTGACCACTGCGTCGGTCGCGTCACCGAGGC
CCTGGCCGAAGTAGGCGGCGAATGCCTGATCACCGCCGACCACGGCAACGCCGAGAAGATGCTGGACGAAGAGACCGGTC
AGGCTCACACAGCCCACACCAACCTGCCGGTTCCCCTCATCTATTTCGGTCGCAAGGCCGAGGTGCTTGAAGGTGGCAAA
CTGTCCGATCTGGCCCCGACCATGCTGACCCTGATGGGTCTTCCTGTGCCGCCGGAAATGACTGGCAAGCCCCTGATGAT
TCTGAAATAA

Upstream 100 bases:

>100_bases
GGCAAGGGCTTGGCTATCAGGTGACTATTTCGGCAGATGTAGTAATATTACGCTAGTTTCACTTCCCGCAATTCATTCCT
ATCCGAGAGGACATAGCCTT

Downstream 100 bases:

>100_bases
TCCTTCCCCATGCGGGGATGCGAAGTTATTTCAAACAAAACCAGTCGCGTCGGCCTGTTGGCCGGCGCGCTGTTTTTTTG
CCTGTCGTTTATCGCGGGCA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MSTAKKPLVLVIMDGWGYSTKQEHNAVAAAKTPNLDRLARDYTSTLISGSGLDVGLPDGQMGNSEVGHVNIGAGRIVYQE
LTRISKEIKDGDFFQNVELAKALDSAVTKGKAVHIMGLMSPGGVHSHEEHIMGMIEMAAKRGAEQIYFHAFLDGRDVPPR
SAQSSIEQFDALFARLGKGRFASMIGRYFAMDRDNRWDRVQQAYDLMTQGKGEFTADSASEALAAAYARDENDEFVKATR
IGAAAPMQDGDALIFMNFRADRAREITRAFVDSDFTGFARAATPALNFVMLTEYAADIKTACAYPPTALVNTLGEWLAKQ
GKTQLRISETEKYAHVTFFFNGGEESCFTGEDREIVASPKVATYDLQPEMSSEELTDKLVAAIKSGKYDTIICNYPNGDM
VGHTGVFDAAVKACEAVDHCVGRVTEALAEVGGECLITADHGNAEKMLDEETGQAHTAHTNLPVPLIYFGRKAEVLEGGK
LSDLAPTMLTLMGLPVPPEMTGKPLMILK

Sequences:

>Translated_509_residues
MSTAKKPLVLVIMDGWGYSTKQEHNAVAAAKTPNLDRLARDYTSTLISGSGLDVGLPDGQMGNSEVGHVNIGAGRIVYQE
LTRISKEIKDGDFFQNVELAKALDSAVTKGKAVHIMGLMSPGGVHSHEEHIMGMIEMAAKRGAEQIYFHAFLDGRDVPPR
SAQSSIEQFDALFARLGKGRFASMIGRYFAMDRDNRWDRVQQAYDLMTQGKGEFTADSASEALAAAYARDENDEFVKATR
IGAAAPMQDGDALIFMNFRADRAREITRAFVDSDFTGFARAATPALNFVMLTEYAADIKTACAYPPTALVNTLGEWLAKQ
GKTQLRISETEKYAHVTFFFNGGEESCFTGEDREIVASPKVATYDLQPEMSSEELTDKLVAAIKSGKYDTIICNYPNGDM
VGHTGVFDAAVKACEAVDHCVGRVTEALAEVGGECLITADHGNAEKMLDEETGQAHTAHTNLPVPLIYFGRKAEVLEGGK
LSDLAPTMLTLMGLPVPPEMTGKPLMILK
>Mature_508_residues
STAKKPLVLVIMDGWGYSTKQEHNAVAAAKTPNLDRLARDYTSTLISGSGLDVGLPDGQMGNSEVGHVNIGAGRIVYQEL
TRISKEIKDGDFFQNVELAKALDSAVTKGKAVHIMGLMSPGGVHSHEEHIMGMIEMAAKRGAEQIYFHAFLDGRDVPPRS
AQSSIEQFDALFARLGKGRFASMIGRYFAMDRDNRWDRVQQAYDLMTQGKGEFTADSASEALAAAYARDENDEFVKATRI
GAAAPMQDGDALIFMNFRADRAREITRAFVDSDFTGFARAATPALNFVMLTEYAADIKTACAYPPTALVNTLGEWLAKQG
KTQLRISETEKYAHVTFFFNGGEESCFTGEDREIVASPKVATYDLQPEMSSEELTDKLVAAIKSGKYDTIICNYPNGDMV
GHTGVFDAAVKACEAVDHCVGRVTEALAEVGGECLITADHGNAEKMLDEETGQAHTAHTNLPVPLIYFGRKAEVLEGGKL
SDLAPTMLTLMGLPVPPEMTGKPLMILK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=514, Percent_Identity=71.5953307392996, Blast_Score=761, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17507741, Length=511, Percent_Identity=45.0097847358121, Blast_Score=430, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI32564249, Length=511, Percent_Identity=45.0097847358121, Blast_Score=430, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_AERS4 (A4ST23)

Other databases:

- EMBL:   CP000644
- RefSeq:   YP_001143793.1
- ProteinModelPortal:   A4ST23
- SMR:   A4ST23
- STRING:   A4ST23
- GeneID:   4997160
- GenomeReviews:   CP000644_GR
- KEGG:   asa:ASA_4104
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DNKTDEF
- PhylomeDB:   A4ST23
- ProtClustDB:   PRK05434
- BioCyc:   ASAL382245:ASA_4104-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 55276; Mature: 55145

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: ACT_SITE 64-64

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAKKPLVLVIMDGWGYSTKQEHNAVAAAKTPNLDRLARDYTSTLISGSGLDVGLPDGQ
CCCCCCCEEEEEECCCCCCCCHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
MGNSEVGHVNIGAGRIVYQELTRISKEIKDGDFFQNVELAKALDSAVTKGKAVHIMGLMS
CCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECC
PGGVHSHEEHIMGMIEMAAKRGAEQIYFHAFLDGRDVPPRSAQSSIEQFDALFARLGKGR
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCH
FASMIGRYFAMDRDNRWDRVQQAYDLMTQGKGEFTADSASEALAAAYARDENDEFVKATR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
IGAAAPMQDGDALIFMNFRADRAREITRAFVDSDFTGFARAATPALNFVMLTEYAADIKT
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ACAYPPTALVNTLGEWLAKQGKTQLRISETEKYAHVTFFFNGGEESCFTGEDREIVASPK
HCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEECCC
VATYDLQPEMSSEELTDKLVAAIKSGKYDTIICNYPNGDMVGHTGVFDAAVKACEAVDHC
EEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
VGRVTEALAEVGGECLITADHGNAEKMLDEETGQAHTAHTNLPVPLIYFGRKAEVLEGGK
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCEEECCCCCEEEEEECCCHHHCCCCC
LSDLAPTMLTLMGLPVPPEMTGKPLMILK
CCHHHHHHHHHHCCCCCCCCCCCCEEEEC
>Mature Secondary Structure 
STAKKPLVLVIMDGWGYSTKQEHNAVAAAKTPNLDRLARDYTSTLISGSGLDVGLPDGQ
CCCCCCEEEEEECCCCCCCCHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
MGNSEVGHVNIGAGRIVYQELTRISKEIKDGDFFQNVELAKALDSAVTKGKAVHIMGLMS
CCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECC
PGGVHSHEEHIMGMIEMAAKRGAEQIYFHAFLDGRDVPPRSAQSSIEQFDALFARLGKGR
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCH
FASMIGRYFAMDRDNRWDRVQQAYDLMTQGKGEFTADSASEALAAAYARDENDEFVKATR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
IGAAAPMQDGDALIFMNFRADRAREITRAFVDSDFTGFARAATPALNFVMLTEYAADIKT
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ACAYPPTALVNTLGEWLAKQGKTQLRISETEKYAHVTFFFNGGEESCFTGEDREIVASPK
HCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEECCC
VATYDLQPEMSSEELTDKLVAAIKSGKYDTIICNYPNGDMVGHTGVFDAAVKACEAVDHC
EEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
VGRVTEALAEVGGECLITADHGNAEKMLDEETGQAHTAHTNLPVPLIYFGRKAEVLEGGK
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCEEECCCCCEEEEEECCCHHHCCCCC
LSDLAPTMLTLMGLPVPPEMTGKPLMILK
CCHHHHHHHHHHCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA