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The map label for this gene is nfuA [H]

Identifier: 145300948

GI number: 145300948

Start: 4388269

End: 4388847

Strand: Direct

Name: nfuA [H]

Synonym: ASA_4100

Alternate gene names: 145300948

Gene position: 4388269-4388847 (Clockwise)

Preceding gene: 145300947

Following gene: 145300952

Centisome position: 93.32

GC content: 56.82

Gene sequence:

>579_bases
ATGATCAGCATTTCCGACACCGCCCAGGCCCATTTCCGTAAACTGCTGAAAAAACAGCCTGATGGCACCAATATCCGGGT
GTTTGTGGTCAATCCGGGAACCCAGAATGCCGAGTGCGGCGTATCATATTGCCCGCCCGATGCGGTGGATCCGGAAGATC
AACACCTGCCTTTCAGCGGATTCGACTGCCTAGTTGATCCTCTGAGCGCCCCTTACCTGGTCGATGCCACCATCGACTTC
GTCACCGACCAGATGGGCTCCCAGCTCACCCTCAAAGCACCAAACGCCAAGATGCGCAAAGTAGCCGACGATGCACCGCT
GATCGACCGCATTGAATATGTGCTGATGTCCGAGGTCAACCCCATGCTGGCCGGTCACGGTGGCAAGGTAACTCTGGTCG
AGCTGACCGAAGACAAGCTGGCCATCCTGCAGTTTGGCGGCGGTTGCAACGGTTGCTCCATGGTCGATTACACCCTGAAA
GAGGGGATCGAGAAGCAGCTGCTGGAAAAATTCCCTGGCGAGCTCAACGGCGTCAAAGATGCCACCGAGCACCAGCGCGG
CGATCACTCCTACTATTGA

Upstream 100 bases:

>100_bases
TATTTGACATATGTTAAGCGCCATCTGCATGCTACCCAAGCACTGCCAAGCGAGTTATCATGAATACCCTAGTCGTACAC
TCAGGTTTATGAGGATAGTG

Downstream 100 bases:

>100_bases
TCCCGTGCCAGTGGCGATCATCCATCAGGGTTGATCCCCTCTGACCGCACATGAAAAGGCCCCGCCAATCTGGCAGGGCC
TTTTGCTATCCGGCAAACGG

Product: DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MISISDTAQAHFRKLLKKQPDGTNIRVFVVNPGTQNAECGVSYCPPDAVDPEDQHLPFSGFDCLVDPLSAPYLVDATIDF
VTDQMGSQLTLKAPNAKMRKVADDAPLIDRIEYVLMSEVNPMLAGHGGKVTLVELTEDKLAILQFGGGCNGCSMVDYTLK
EGIEKQLLEKFPGELNGVKDATEHQRGDHSYY

Sequences:

>Translated_192_residues
MISISDTAQAHFRKLLKKQPDGTNIRVFVVNPGTQNAECGVSYCPPDAVDPEDQHLPFSGFDCLVDPLSAPYLVDATIDF
VTDQMGSQLTLKAPNAKMRKVADDAPLIDRIEYVLMSEVNPMLAGHGGKVTLVELTEDKLAILQFGGGCNGCSMVDYTLK
EGIEKQLLEKFPGELNGVKDATEHQRGDHSYY
>Mature_192_residues
MISISDTAQAHFRKLLKKQPDGTNIRVFVVNPGTQNAECGVSYCPPDAVDPEDQHLPFSGFDCLVDPLSAPYLVDATIDF
VTDQMGSQLTLKAPNAKMRKVADDAPLIDRIEYVLMSEVNPMLAGHGGKVTLVELTEDKLAILQFGGGCNGCSMVDYTLK
EGIEKQLLEKFPGELNGVKDATEHQRGDHSYY

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins [H]

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family [H]

Homologues:

Organism=Escherichia coli, GI1789819, Length=192, Percent_Identity=75, Blast_Score=300, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- ProDom:   PD002830 [H]

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU [H]

EC number: NA

Molecular weight: Translated: 21003; Mature: 21003

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISISDTAQAHFRKLLKKQPDGTNIRVFVVNPGTQNAECGVSYCPPDAVDPEDQHLPFSG
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCC
FDCLVDPLSAPYLVDATIDFVTDQMGSQLTLKAPNAKMRKVADDAPLIDRIEYVLMSEVN
CHHHHCCCCCCEEEEHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHCC
PMLAGHGGKVTLVELTEDKLAILQFGGGCNGCSMVDYTLKEGIEKQLLEKFPGELNGVKD
HHHCCCCCEEEEEEECCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCC
ATEHQRGDHSYY
HHHHCCCCCCCC
>Mature Secondary Structure
MISISDTAQAHFRKLLKKQPDGTNIRVFVVNPGTQNAECGVSYCPPDAVDPEDQHLPFSG
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCC
FDCLVDPLSAPYLVDATIDFVTDQMGSQLTLKAPNAKMRKVADDAPLIDRIEYVLMSEVN
CHHHHCCCCCCEEEEHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHCC
PMLAGHGGKVTLVELTEDKLAILQFGGGCNGCSMVDYTLKEGIEKQLLEKFPGELNGVKD
HHHCCCCCEEEEEEECCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCC
ATEHQRGDHSYY
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA