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The map label for this gene is qmcA [H]

Identifier: 145300400

GI number: 145300400

Start: 3817252

End: 3818175

Strand: Direct

Name: qmcA [H]

Synonym: ASA_3525

Alternate gene names: 145300400

Gene position: 3817252-3818175 (Clockwise)

Preceding gene: 145300394

Following gene: 145300401

Centisome position: 81.18

GC content: 59.52

Gene sequence:

>924_bases
ATGAATGAGTCATTGATTGTGCTAGGGATCTTCGTGTTCCTGGTGATCGTCACCCTGGGTGCCGGCATCAAGATAGTGCC
GCAAGGCTACAACTGGACAGTGGAGCGCTTCGGCCGCTACACCCGCACTCTCTCCCCCGGCCTCAACCTGCTTATCCCCT
ATGTGGATAGAGTCGGTCACAAGATCATCATGATGGAGCAGGTGCTGGACATACCGGCGCAAGAGGTGATCTCCCGCGAC
AACGCCAACGTCACCATAGACGCCATCAGCTTCGTGCAGGTGGTGGATGCCCGCAAAGCCGCCTACGAGGTCAACGATCT
CACCAGCGCCATTCGCAATCTCACCATGACCAATATGCGGACAGTGCTGGGCGCCATGGAGCTGGACGAGATGCTCTCCC
AGCGTGACACCATCAACGAGAAGCTGCTGCGCACCATGGATGCCGCCACCGCCCCCTGGGGCATCAAGGTGACCCGGATC
GAGATCAAGGATGTACGTCCGCCGCTGGCGCTGGTGGAAGCCATGAACGCCCAGATGAAGGCCGAGCGCCAGAAACGGGC
CGAAGTACTGGAAGCCGAAGGGGTGCGCCAGTCCAAGATCCTGAAAGCGGAAGGCGAAAAGCAGTCCCAGATCCTCAAGG
CCGAGGGTGAGCGTCAGGCCGCCTTCCTCGCCGCCGAAGCGCGGGAGCGGGCTGCCGAGGCGGAAGCCAAGGCGACTCAT
ATGGTCTCAAAAGCTATAGCGGAAGGGGATATGCAGGCCATCAACTACTTCGTGGCCCAGAAGTACACGGAAGCACTGGC
CCGTATCGGCGAAGGCCCCAACAGCAAGATCATCATGATGCCGCTGGAAGCGGGCAGCTTGATCGGCTCGATAGCCGGCA
TGGCCGAGATGTTCAACAAAGATGGCAAGGGTAACAAGTCATGA

Upstream 100 bases:

>100_bases
TAATTAGCAAAGCCATATGATGACAAAGGCGGACGATCATCCTTGTGGTGCTCGGCGCAAGGCCATAGGCTAGTGAATGT
GTTTCATAAGGAGCTAGATA

Downstream 100 bases:

>100_bases
CAGCCCTGCTCGAGGGGCTGACCCACTGGCACTGGCTGGGGCTGGGTTTCATCCTCTTGGCCATAGAAGTGCTGGGGTCG
GTAGGCTTTTTGCTCTGGAC

Product: membrane protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNESLIVLGIFVFLVIVTLGAGIKIVPQGYNWTVERFGRYTRTLSPGLNLLIPYVDRVGHKIIMMEQVLDIPAQEVISRD
NANVTIDAISFVQVVDARKAAYEVNDLTSAIRNLTMTNMRTVLGAMELDEMLSQRDTINEKLLRTMDAATAPWGIKVTRI
EIKDVRPPLALVEAMNAQMKAERQKRAEVLEAEGVRQSKILKAEGEKQSQILKAEGERQAAFLAAEARERAAEAEAKATH
MVSKAIAEGDMQAINYFVAQKYTEALARIGEGPNSKIIMMPLEAGSLIGSIAGMAEMFNKDGKGNKS

Sequences:

>Translated_307_residues
MNESLIVLGIFVFLVIVTLGAGIKIVPQGYNWTVERFGRYTRTLSPGLNLLIPYVDRVGHKIIMMEQVLDIPAQEVISRD
NANVTIDAISFVQVVDARKAAYEVNDLTSAIRNLTMTNMRTVLGAMELDEMLSQRDTINEKLLRTMDAATAPWGIKVTRI
EIKDVRPPLALVEAMNAQMKAERQKRAEVLEAEGVRQSKILKAEGEKQSQILKAEGERQAAFLAAEARERAAEAEAKATH
MVSKAIAEGDMQAINYFVAQKYTEALARIGEGPNSKIIMMPLEAGSLIGSIAGMAEMFNKDGKGNKS
>Mature_307_residues
MNESLIVLGIFVFLVIVTLGAGIKIVPQGYNWTVERFGRYTRTLSPGLNLLIPYVDRVGHKIIMMEQVLDIPAQEVISRD
NANVTIDAISFVQVVDARKAAYEVNDLTSAIRNLTMTNMRTVLGAMELDEMLSQRDTINEKLLRTMDAATAPWGIKVTRI
EIKDVRPPLALVEAMNAQMKAERQKRAEVLEAEGVRQSKILKAEGEKQSQILKAEGERQAAFLAAEARERAAEAEAKATH
MVSKAIAEGDMQAINYFVAQKYTEALARIGEGPNSKIIMMPLEAGSLIGSIAGMAEMFNKDGKGNKS

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=273, Percent_Identity=36.6300366300366, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI21686995, Length=214, Percent_Identity=36.4485981308411, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI221316744, Length=214, Percent_Identity=36.4485981308411, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI38016911, Length=189, Percent_Identity=36.5079365079365, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI7657615, Length=193, Percent_Identity=30.0518134715026, Blast_Score=95, Evalue=9e-20,
Organism=Escherichia coli, GI1786697, Length=303, Percent_Identity=72.2772277227723, Blast_Score=464, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI32564147, Length=282, Percent_Identity=35.1063829787234, Blast_Score=173, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17569493, Length=216, Percent_Identity=34.2592592592593, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI193209764, Length=216, Percent_Identity=34.2592592592593, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17569497, Length=195, Percent_Identity=32.3076923076923, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71987612, Length=208, Percent_Identity=33.6538461538462, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI25153583, Length=208, Percent_Identity=33.6538461538462, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71989948, Length=161, Percent_Identity=36.0248447204969, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71989955, Length=161, Percent_Identity=36.0248447204969, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71987621, Length=208, Percent_Identity=33.6538461538462, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17569499, Length=194, Percent_Identity=34.020618556701, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17570459, Length=206, Percent_Identity=33.9805825242718, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32566490, Length=195, Percent_Identity=31.7948717948718, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210507, Length=187, Percent_Identity=32.620320855615, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17570161, Length=187, Percent_Identity=32.620320855615, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71989963, Length=124, Percent_Identity=33.8709677419355, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17542664, Length=169, Percent_Identity=27.2189349112426, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45550506, Length=290, Percent_Identity=34.8275862068965, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI45556022, Length=200, Percent_Identity=35, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI18860517, Length=196, Percent_Identity=31.6326530612245, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281361633, Length=231, Percent_Identity=25.974025974026, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281361631, Length=231, Percent_Identity=25.974025974026, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24657857, Length=195, Percent_Identity=34.3589743589744, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI62484448, Length=195, Percent_Identity=34.3589743589744, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281365664, Length=195, Percent_Identity=34.3589743589744, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI62484274, Length=195, Percent_Identity=34.3589743589744, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356845, Length=238, Percent_Identity=24.7899159663866, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28573263, Length=200, Percent_Identity=26, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281361635, Length=140, Percent_Identity=24.2857142857143, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 33794; Mature: 33794

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESLIVLGIFVFLVIVTLGAGIKIVPQGYNWTVERFGRYTRTLSPGLNLLIPYVDRVGH
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KIIMMEQVLDIPAQEVISRDNANVTIDAISFVQVVDARKAAYEVNDLTSAIRNLTMTNMR
HHHHHHHHHCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVLGAMELDEMLSQRDTINEKLLRTMDAATAPWGIKVTRIEIKDVRPPLALVEAMNAQMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
AERQKRAEVLEAEGVRQSKILKAEGEKQSQILKAEGERQAAFLAAEARERAAEAEAKATH
HHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
MVSKAIAEGDMQAINYFVAQKYTEALARIGEGPNSKIIMMPLEAGSLIGSIAGMAEMFNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCC
DGKGNKS
CCCCCCC
>Mature Secondary Structure
MNESLIVLGIFVFLVIVTLGAGIKIVPQGYNWTVERFGRYTRTLSPGLNLLIPYVDRVGH
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KIIMMEQVLDIPAQEVISRDNANVTIDAISFVQVVDARKAAYEVNDLTSAIRNLTMTNMR
HHHHHHHHHCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVLGAMELDEMLSQRDTINEKLLRTMDAATAPWGIKVTRIEIKDVRPPLALVEAMNAQMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
AERQKRAEVLEAEGVRQSKILKAEGEKQSQILKAEGERQAAFLAAEARERAAEAEAKATH
HHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
MVSKAIAEGDMQAINYFVAQKYTEALARIGEGPNSKIIMMPLEAGSLIGSIAGMAEMFNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCC
DGKGNKS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]