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The map label for this gene is ftsW [C]

Identifier: 145296121

GI number: 145296121

Start: 2247771

End: 2249423

Strand: Reverse

Name: ftsW [C]

Synonym: cgR_2041

Alternate gene names: 145296121

Gene position: 2249423-2247771 (Counterclockwise)

Preceding gene: 145296122

Following gene: 145296120

Centisome position: 67.87

GC content: 55.78

Gene sequence:

>1653_bases
ATGACCACCGGAGCCTCAAAAAAACCCGCACGTCCGAACACTGGCGCTAAAACCAGAACGGGGCTGGGAATTAGGGAGCG
TATTTCCGGTGCATGGAATGATCTTCTCGCGCGCCCTTTAACTGACTACATCATGATCTTGTGCATCGTGGTCATTTTGT
CGTGCCTCGGTGTAGTCATGGTGTATTCCTCCTCAATGACATGGTCGTTGAGGGAAGGTGGCTCCGTGTGGGCTACTGCC
GTGCGCCAGGGCATCATGATCGTGTTGGGTTTCTTTGCCATGTGGGTGGCGTTGATGACGCGCCCGCAAACCATTAGAAA
CCTATCCAACCTGATATTGATTGTGTCTATTGTCTTGCTGCTTGCCGTGCAGATTCCTGGCATTGGTACAGGTAAAGAAG
AGGTCGGGTCGCAGTCGTGGATTGCTCTTGGACCTATTCAGTTTCAGCCTTCGGAGATCGCCAAAGTGGCCATTGCCGTG
TGGGGAGCGCACTACCTCGCAGGCAAGGGCCCTGTGCAGCACTGGTTCAATAACCACTTGATGCGTTTTGGTGGCGTCGG
TGCATTCATGGCGTTTTTGATCTTCATGGAAGGCGACGCCGGCATGGCGATGTCTTTCGTGCTGGTTGTATTGTTCATGC
TGTTTTTTGCGGGCATCGCCATGGGTTGGATCGCGATTGCCGGCGTACTGATTATCGCAGCCCTCGCAGTCCTGGCATTG
GGCGGAGGCTTCCGTTCAAGCCGATTCGAGGTGTATTTCGATGCGCTGTTTGGCAATTTTCACGATGTGCGAGGCATTGC
CTTCCAGTCCTATCAGGGCTTCCTCTCTCTTGCAGATGGTTCCGGCTTGGGAGTTGGTTTGGGCCAATCAAGGGCGAAGT
GGTTCTACCTGCCCGAAGCTAAAAATGACTTCATCTTTGCCATCATTGGTGAGGAGCTGGGGCTGTGGGGTGGCGCTCTG
GTCATCGCACTTTTCGCGGGGCTGCTGTACTTCGGTCTGCGCACAGCTAAGAAGAGCCACGATCCATTCTTGGGCTTGAT
GGCTGCAACCTTGACGGCATCCGTGGTGTCGCAGGCGTTCATCAACATTGGCTACGTGGTTGGTCTGCTGCCAGTTACCG
GTATTCAGCTGCCCATGATTTCCGCCGGTGGTACCTCCGCGATCATTACCTTGGCTTCCATGGGCTTGCTCATTAGCTGT
GCACGCCACGAACCAGAGACAGTTTCTGCGATGGCTTCCTATGGACGCCCCGCAATCGATCGACTTCTGGGATTGCGTGA
GCCTTCAAGTACTTTGACCGCCAGTAATGCATCCTTGCGTTCCAACAAAACCAAGGCCGCTAGACAAAAGCCGAGTCCTC
AGAAAGAGTCTCGGGACCGCTTCGGCGAGCCTGTGACCGCACGCCGAGCGCAGGCGCCACGAAGTGGGCGAGCTGGAGTA
CAATCGGAAGCTCCGCGACGCTCGACTGGTAGCGTCAAAGGTCGAAGCAGTGGTCAGGACAACGGTCGAGGCAACGAAGG
TACGGCGCGTAGCCAATCAACTACTGGTGGGCGCGCAGCCGATCGCAGCGTTGATCGAAGTCGTCAAAGCAGGCCTACCG
AGCGCCGTTCCGAGTCGCGCGATGATTGGCGTGACAACCGCAACCGCAGATAA

Upstream 100 bases:

>100_bases
CGTCTTTGGACATGTTCAAAGGCATGGGCCAGCGTGGCGACCTCTTTGCACACAACATCATTGGCACAATCAAAGGATTA
ACGGAAGAGAAAGGCTGATC

Downstream 100 bases:

>100_bases
ATGTGAAATCAGGAGAACTACGAATAAAGATGGCTAACTCCCCAAAACCCATGCGGGTTGTCGTTGCTGGTGGCGGTACC
GCAGGACATATTGAGCCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTTGASKKPARPNTGAKTRTGLGIRERISGAWNDLLARPLTDYIMILCIVVILSCLGVVMVYSSSMTWSLREGGSVWATA
VRQGIMIVLGFFAMWVALMTRPQTIRNLSNLILIVSIVLLLAVQIPGIGTGKEEVGSQSWIALGPIQFQPSEIAKVAIAV
WGAHYLAGKGPVQHWFNNHLMRFGGVGAFMAFLIFMEGDAGMAMSFVLVVLFMLFFAGIAMGWIAIAGVLIIAALAVLAL
GGGFRSSRFEVYFDALFGNFHDVRGIAFQSYQGFLSLADGSGLGVGLGQSRAKWFYLPEAKNDFIFAIIGEELGLWGGAL
VIALFAGLLYFGLRTAKKSHDPFLGLMAATLTASVVSQAFINIGYVVGLLPVTGIQLPMISAGGTSAIITLASMGLLISC
ARHEPETVSAMASYGRPAIDRLLGLREPSSTLTASNASLRSNKTKAARQKPSPQKESRDRFGEPVTARRAQAPRSGRAGV
QSEAPRRSTGSVKGRSSGQDNGRGNEGTARSQSTTGGRAADRSVDRSRQSRPTERRSESRDDWRDNRNRR

Sequences:

>Translated_550_residues
MTTGASKKPARPNTGAKTRTGLGIRERISGAWNDLLARPLTDYIMILCIVVILSCLGVVMVYSSSMTWSLREGGSVWATA
VRQGIMIVLGFFAMWVALMTRPQTIRNLSNLILIVSIVLLLAVQIPGIGTGKEEVGSQSWIALGPIQFQPSEIAKVAIAV
WGAHYLAGKGPVQHWFNNHLMRFGGVGAFMAFLIFMEGDAGMAMSFVLVVLFMLFFAGIAMGWIAIAGVLIIAALAVLAL
GGGFRSSRFEVYFDALFGNFHDVRGIAFQSYQGFLSLADGSGLGVGLGQSRAKWFYLPEAKNDFIFAIIGEELGLWGGAL
VIALFAGLLYFGLRTAKKSHDPFLGLMAATLTASVVSQAFINIGYVVGLLPVTGIQLPMISAGGTSAIITLASMGLLISC
ARHEPETVSAMASYGRPAIDRLLGLREPSSTLTASNASLRSNKTKAARQKPSPQKESRDRFGEPVTARRAQAPRSGRAGV
QSEAPRRSTGSVKGRSSGQDNGRGNEGTARSQSTTGGRAADRSVDRSRQSRPTERRSESRDDWRDNRNRR
>Mature_549_residues
TTGASKKPARPNTGAKTRTGLGIRERISGAWNDLLARPLTDYIMILCIVVILSCLGVVMVYSSSMTWSLREGGSVWATAV
RQGIMIVLGFFAMWVALMTRPQTIRNLSNLILIVSIVLLLAVQIPGIGTGKEEVGSQSWIALGPIQFQPSEIAKVAIAVW
GAHYLAGKGPVQHWFNNHLMRFGGVGAFMAFLIFMEGDAGMAMSFVLVVLFMLFFAGIAMGWIAIAGVLIIAALAVLALG
GGFRSSRFEVYFDALFGNFHDVRGIAFQSYQGFLSLADGSGLGVGLGQSRAKWFYLPEAKNDFIFAIIGEELGLWGGALV
IALFAGLLYFGLRTAKKSHDPFLGLMAATLTASVVSQAFINIGYVVGLLPVTGIQLPMISAGGTSAIITLASMGLLISCA
RHEPETVSAMASYGRPAIDRLLGLREPSSTLTASNASLRSNKTKAARQKPSPQKESRDRFGEPVTARRAQAPRSGRAGVQ
SEAPRRSTGSVKGRSSGQDNGRGNEGTARSQSTTGGRAADRSVDRSRQSRPTERRSESRDDWRDNRNRR

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=361, Percent_Identity=32.409972299169, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1786853, Length=350, Percent_Identity=30.2857142857143, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 59071; Mature: 58940

Theoretical pI: Translated: 11.11; Mature: 11.11

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGASKKPARPNTGAKTRTGLGIRERISGAWNDLLARPLTDYIMILCIVVILSCLGVVM
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYSSSMTWSLREGGSVWATAVRQGIMIVLGFFAMWVALMTRPQTIRNLSNLILIVSIVLL
HHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LAVQIPGIGTGKEEVGSQSWIALGPIQFQPSEIAKVAIAVWGAHYLAGKGPVQHWFNNHL
HHHHCCCCCCCHHHHCCCCEEEECCCEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MRFGGVGAFMAFLIFMEGDAGMAMSFVLVVLFMLFFAGIAMGWIAIAGVLIIAALAVLAL
HHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGGFRSSRFEVYFDALFGNFHDVRGIAFQSYQGFLSLADGSGLGVGLGQSRAKWFYLPEA
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCEEECCCCCCEECCCCCCCEEEECCCC
KNDFIFAIIGEELGLWGGALVIALFAGLLYFGLRTAKKSHDPFLGLMAATLTASVVSQAF
CCCEEEEEECCHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
INIGYVVGLLPVTGIQLPMISAGGTSAIITLASMGLLISCARHEPETVSAMASYGRPAID
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHH
RLLGLREPSSTLTASNASLRSNKTKAARQKPSPQKESRDRFGEPVTARRAQAPRSGRAGV
HHHCCCCCCCCEECCCCHHHCCCHHHHHCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCC
QSEAPRRSTGSVKGRSSGQDNGRGNEGTARSQSTTGGRAADRSVDRSRQSRPTERRSESR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCH
DDWRDNRNRR
HHHHHCCCCC
>Mature Secondary Structure 
TTGASKKPARPNTGAKTRTGLGIRERISGAWNDLLARPLTDYIMILCIVVILSCLGVVM
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYSSSMTWSLREGGSVWATAVRQGIMIVLGFFAMWVALMTRPQTIRNLSNLILIVSIVLL
HHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LAVQIPGIGTGKEEVGSQSWIALGPIQFQPSEIAKVAIAVWGAHYLAGKGPVQHWFNNHL
HHHHCCCCCCCHHHHCCCCEEEECCCEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MRFGGVGAFMAFLIFMEGDAGMAMSFVLVVLFMLFFAGIAMGWIAIAGVLIIAALAVLAL
HHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGGFRSSRFEVYFDALFGNFHDVRGIAFQSYQGFLSLADGSGLGVGLGQSRAKWFYLPEA
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCEEECCCCCCEECCCCCCCEEEECCCC
KNDFIFAIIGEELGLWGGALVIALFAGLLYFGLRTAKKSHDPFLGLMAATLTASVVSQAF
CCCEEEEEECCHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
INIGYVVGLLPVTGIQLPMISAGGTSAIITLASMGLLISCARHEPETVSAMASYGRPAID
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHH
RLLGLREPSSTLTASNASLRSNKTKAARQKPSPQKESRDRFGEPVTARRAQAPRSGRAGV
HHHCCCCCCCCEECCCCHHHCCCHHHHHCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCC
QSEAPRRSTGSVKGRSSGQDNGRGNEGTARSQSTTGGRAADRSVDRSRQSRPTERRSESR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCH
DDWRDNRNRR
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]